Flexibility in Fixation An Update On Femur Fractures in Children

You might also like

Download as pdf or txt
Download as pdf or txt
You are on page 1of 8

TRAUMA SUPPLEMENT

Flexibility in Fixation: An Update on Femur


Fractures in Children
Unni G. Narayanan, MBBS, MSc, FRCS(C)* and Jonathan H. Phillips, BSc, MBBSw

provide adequate stabilization to maximize comfort and


Abstract: Although non-operative strategies remain a viable permit early mobilization, minimize caregiving needs,
option for the management of some children’s femur fractures, avoid or minimize scarring, avoid serious complications,
surgical management has become more popular and predictable, and achieve these goals conveniently and cost effectively.
with potential complications better recognized and thus more There is no single classification system of femur
easily avoided. This paper addresses the operative management fractures that has shown to have clinical utility. Prog-
of children’s femur fractures highlighting the multiple techni- nostic factors that will influence decision making include
ques available to treat the spectrum of pediatric femur fractures. the age and weight of the child, the level of the fracture
We present the applications of Elastic Stable Intramedullary (proximal, middle, or distal), the fracture pattern (trans-
Nailing and Locked intramedullary nailing, sub-muscular or verse, oblique, spiral), magnitude of displacement, extent
open plating, and external fixation, and discuss the relative ad- of comminution, soft tissue injury including open frac-
vantages and shortcomings of each technique. Cases are pre- tures, and the presence of other significant injuries.
sented for illustration.
Key Words: femur fracture, pediatric, children, operative NONOPERATIVE MANAGEMENT
management, fixation No discussion of the operative management of fe-
mur fractures in children would be complete without a
(J Pediatr Orthop 2012;32:S32–S39) brief note on the nonoperative methods, the mainstay of
which is the spica cast. Early application of spica cast
after a closed reduction, typically under a general anes-
F ractures of the femur account for the most common
major orthopaedic injury in children.1 Femoral frac-
tures in children are generally perceived to heal satisfac-
thetic, remains an effective method of treatment for most
femur fractures in younger children.4–6 The optimal limit
for age, weight, or size has not been well studied, but most
torily irrespective of the form of treatment. Unlike adult believe that a spica cast is a viable treatment option for
femoral fractures that are almost universally treated with children up to 60 pounds. This method has the advantage
locked intramedullary nails, femoral fractures in children of avoiding any scarring or risk of infection, requires
are treated by a variety of methods including immediate minimal hospitalization, and, if unsuccessful in maintain-
spica cast or traction followed by spica cast, internal ing an adequate reduction, does not preclude switching to
fixation with compression or bridge plating, external fix- an alternate method of treatment. It has the disadvantage
ation, and flexible or rigid intramedullary nailing. Indeed, of being associated with a more frequent loss of reduction,
a systematic review of the literature provides little evi- malunion, and shortening.7–10 The spica cast might be less
dence to support one method of treatment over another.2 comfortable to endure especially in summer months and
The choice of treatment may be influenced by the age and imposes a greater burden on parents or caregivers for the
weight of the child, the level and pattern of the fracture, duration of the casting.11
and to a great extent, by regional, institutional, or sur-
geons’ preferences.3 The ideal treatment method should METHODS OF FIXATION

From the *Divisions of Orthopaedic Surgery & Child Health Evaluative


Elastic Stable Intramedullary Nailing
Sciences, The Hospital for Sick Children, University of Toronto, The concept of “elastic stability” was popularized in
Toronto, ON, Canada; and wArnold Palmer Hospital Pediatric Nancy, France.12,13 Ligier et al14 reported the results of
Specialty Practice, Orlando, FL. the Nancy experience followed by others who have also
J.H.P. has received royalties and consultancy fees from Biomet for his
design of a flexible locked intramedullary nail for pediatric femur
reported excellent clinical results with this technique,
fractures. which has been variously called “elastic stable intra-
The authors declare no conflict of interest. medullary nail” fixation, “flexible intramedullary nail”
Reprints: Unni G. Narayanan, MBBS, MSc, FRCS(C), Divisions of fixation, or “Nancy nail” fixation.15,16 Although other
Orthopaedic Surgery & Child Health Evaluative Sciences, The flexible nails preceded the introduction of elastic nails, the
Hospital for Sick Children, 555 University Avenue, S-107, University
of Toronto, Toronto, ON, Canada M5G 1X8. E-mail: unni. use of titanium and its superior elasticity distinguishes the
narayanan@sickkids.ca. technique of elastic intramedullary nailing from previous
Copyright r 2012 by Lippincott Williams & Wilkins flexible nails such as Ender rods, which were made of

S32 | www.pedorthopaedics.com J Pediatr Orthop  Volume 32, Number 1 Supplement, June 2012
J Pediatr Orthop  Volume 32, Number 1 Supplement, June 2012 Femur Fracture Fixation in Children

stainless steel. The flexibility of these, narrower and


therefore less rigid, rods facilitated easier introduction of
the nails into the medullary canal. The stability of the
fixation of Enders rods was derived from filling the me-
dullary canal with 2 or more rods to enhance cortical
contact. In contrast, elastic nails create stability when a
pair of prebent nails, of matched diameter and curvature,
generates an equal and opposite pair of 3-point bending
moments that counteract and balance each other. How-
ever, any significant imbalance in the magnitude or the
direction of the moment created by the 2 nails will result
in angulation of the fracture in the direction of the
stronger nail. Hence, it is important to use nails of the
same diameter, contour them to the same extent and in-
sert them so that the curves of both nails lie in the same
plane. The balanced construct provides elastic stability to
angular, translational, and torsional forces. An external
force applied to the fracture will cause the fracture to
bend, translate, or rotate, but when the force is removed,
the elastic nails will return (elastic recoil) the fracture to
its stable reduced position, as long as any external force
applied to the fracture (including body weight or weight
bearing) does not exceed the elastic limit of the nails. The
fixation is not rigid but sufficiently stable so that no
additional external immobilization is required.13
The ideal indication for elastic nails is a minimally
FIGURE 1. Transverse mid-diaphyseal fracture in a 10-year-old comminuted transverse (or short oblique) mid-diaphyseal
child, who weighs 40 kg (88 lbs).

FIGURE 2. A, Advance the nails so that the tips lie along the supracondylar flare of the distal femur, approximately 1.0 to 1.5 cm
outside of the actual bone entry site. B, Five years after insertion, the distal femur has grown away from ends of nails to become
prominent.

r 2012 Lippincott Williams & Wilkins www.pedorthopaedics.com | S33


Narayanan and Phillips J Pediatr Orthop  Volume 32, Number 1 Supplement, June 2012

femur fracture in a 6- to 12-year-old child who weighs removal of these nails will necessitate a second set of more
<60 kg (Fig. 1). proximal incisions and extraction can be difficult. Nails
The most frequent complication associated with should not be removed until the fracture has consolidated
elastic nails is pain and irritation noted at the nail in- and remodeled. In older children, it is unclear whether
sertion site.16,17 For this reason, the developers of this nails should be routinely removed.
technique recommended routine removal of the elastic Loss of reduction and or malunion has been asso-
nails after fracture healing and advocated leaving the nail ciated with the severity of comminution (> 25%)17 and
ends prominent to facilitate subsequent removal. How- length unstable fractures,18 which remain relative con-
ever, this probably contributed to the irritation over the traindications for elastic nailing. However, the use of
prominent nail ends, making removal necessary. It has elastic nails can be extended to more proximal including
been shown that cutting short the ends of the nails and subtrochanteric fractures and some multifragmentary
allowing them to lie against the supracondylar flare of the fractures by modifying the technique to take advantage of
distal femur minimizes their prominence and reduces the the principles of elastic stability outlined above.19 As the
rate of nail-site irritation17 (Fig. 2A). Nails should body weight of older children and adolescents approaches
probably be removed when used in young children, be- that of adults, there is a concern that elastic nails may not
cause the growth of the distal femur away from the ends provide sufficient stability to prevent loss of reduction.
of the rods leaves the ends lying much more proximal in Moroz et al20 found a 5 times higher risk of poor outcome
the diaphysis where they become prominent and become a in children whose weight was >49 kg. In contrast, in a
source of pain and irritation (Fig. 2B). If left in situ, late more recent study comparing different methods of fixation

FIGURE 3. A 13-year-old boy (skeletally immature) who weighs 65 kg (143 lbs), with isolated closed femoral fracture from a
skiing injury. A and B, Radiographs demonstrate a long spiral, comminuted ( > 75%) fracture of the proximal and mid-diaphysis.
C and D, Postoperative radiographs following antegrade intramedullary nail through trochanteric entry point. E and F, Twelve
months after injury.

S34 | www.pedorthopaedics.com r 2012 Lippincott Williams & Wilkins


J Pediatr Orthop  Volume 32, Number 1 Supplement, June 2012 Femur Fracture Fixation in Children

of femur fractures in adolescents (n = 194) that included adjusting for other risk factors.19 In response to these
105 adolescents treated with elastic nails (12 to 18 y) who concerns, some use stainless-steel rods for more rigidity.
had a mean weight of 47.6 kg (up to a maximum 80 kg),
there was no significant association between age and/or Locked Intramedullary Nails
body weight and the rate of complications in the entire Rigid (locked) intramedullary nailing is the stand-
cohort or as well as within the elastic nail group, even after ard treatment for adult femoral fractures. Conventional

FIGURE 4. A and B, Same fracture as given case example, 1 week after retrograde elastic stable intramedullary nailing. C and D,
Eighteen months after injury with solid healing, before implant removal.

r 2012 Lippincott Williams & Wilkins www.pedorthopaedics.com | S35


Narayanan and Phillips J Pediatr Orthop  Volume 32, Number 1 Supplement, June 2012

adult nail systems adopted the pirifomis fossa as the in- can achieve fixation of adequate stability using closed
sertion site, which has been shown in skeletally immature techniques, plating for femoral fractures has generally
children to be associated with a small but devastating risk fallen out of favor. More recently, the concept of sub-
of avascular necrosis (AVN).21 This has prompted the muscular plating has reintroduced plating into the ar-
introduction of rigid nails through the tip of the greater mamentarium of femoral fixation techniques. Advances
trochanter that does not entirely eliminate the risk. Newer in the design, instrumentation, and anatomic fit of inter-
nails have been designed for antegrade introduction nal fixation plates allows for the percutaneous insertion of
through a lateral aspect of the greater trochanter. Some of plates deep to the vastus lateralis and extraperiosteally
these have been designed to retain some flexibility al- to bridge the fracture, which can be reduced by indirect
lowing for custom contouring to facilitate insertion and techniques and stabilized with percutaneous screws. Typi-
reduction, while allowing for interlocking of the nails to cally locking screws are used, which allows the submuscular
confer rotational stability.22 These locked nails are ideally plate to facilitate biological fixation using minimally in-
indicated in heavier children and adolescents and those vasive techniques.23 This technique is especially useful in
with comminuted and length unstable fractures who are length stable diaphyseal or distal metaphyseal fractures of
not optimal candidates for elastic nailing. In the absence the femur.24 In the absence of any symptoms, there is little
of any symptoms, there is little evidence to recommend evidence to recommend that plates should be removed
that locked intramedullary nails should be removed after after the fracture has healed. Removal of plates may
the fracture has healed. expose the child to the risk of refracture.

Plate Fixation External Fixation


Rigid internal fixation of femoral fractures in chil- External fixation was once the most popular method
dren with compression plating necessitates a relatively of fixation for children’s femoral fractures.25 In a multi-
large incision to achieve the open reduction and appli- centre randomized trial of isolated diaphyseal femur
cation of the plate.21 With the advent of alternatives that fractures in children between 6 and 10 years old, external

FIGURE 5. A and B, Similar fracture as given case example, after submuscular plating.

S36 | www.pedorthopaedics.com r 2012 Lippincott Williams & Wilkins


J Pediatr Orthop  Volume 32, Number 1 Supplement, June 2012 Femur Fracture Fixation in Children

FIGURE 6. A, B, and C, Similar fracture treated with monolateral external fixator.

fixation was found to be superior to early spica cast ap- rigid nail (Figs. 4A–D) Consider using elastic nails with
plication in terms of preventing malunion but was end caps to prevent shortening.
equivalent in terms of physical function and patient sat- Submuscular plating is another option for treating
isfaction.7 Relative to other methods of fixation, however, femoral shaft fractures. Although it can be performed
external fixation has been associated with a higher risk of using a minimally invasive technique, submuscular plat-
complications including refracture (at the pin sites or ing usually requires multiple incisions and can be ex-
fracture), pin-site infections, delayed union, and unsightly pensive if locked screws are used (Figs. 5A, B).
scars at the pin sites.26 In a comparative cohort study of External fixation can also be used to treat
different methods of fixation of femur fractures in ado- length unstable fractures. It has the advantages of being
lescents, external fixation had the worst record for loss of quick and easy to apply with extensive dissection
reduction and malunion, even after adjusting for prog- (Figs. 6A–C).
nostic patient and fracture characteristics.19 In younger Healing times, however, are longer, and the fixator
children, with stable fracture patterns, it has been re- should not be removed until the fracture consolidates that
placed by elastic nails, and in older children and those may be at least 4 months. Other disadvantages are more
with unstable fracture patterns, it has been replaced by frequent loss of reduction compared with other methods,
locked intramedullary nailing and submuscular plating. pin-site infections, scarring, knee stiffness, and increased
Nevertheless, there remains a role for external fixation risk of refracture, either at the fracture site or through a
of the femur in cases of polytrauma and severe open pin tract.
fractures.
Case 2
Case 1 The second case is that of a 9-year-old boy, who is
The first case was a 13-year-old boy (skeletally im- 40 kg (88 lbs), with an isolated closed femur fracture from
mature) who was 65 kg (143 lbs), with an isolated closed a low-energy injury (fall playing soccer). Radiographs
femoral fracture from a skiing injury. Radiographs show a long oblique/spiral fracture that is shortened 2 to
demonstrate a long spiral, comminuted (> 75%) fracture 3 cm and is rotated B90 degrees (Figs. 7A, B).
of the proximal and mid-diaphysis (Fig. 3). This case Many would recommend treatment with elastic
illustrates many treatment options that can be considered nails. The patient was treated with a rigid trochanteric
with a length unstable femoral shaft fracture in an entry nail locked proximally and distally. He was fully
adolescent. weight bearing by 7 weeks postoperatively and had a
The most popular option currently is an antegrade good result without evidence of proximal femoral growth
rigid locked intramedullary nail, using a (lateral) tro- disturbance or (AVN) (Fig. 7C).
chanteric entry point to avoid the piriformis fossa and the
risk of AVN of his femoral head (Figs. 3A–D). SUMMARY
Elastic nailing is an option for length unstable In 2009, the American Academy of Orthopaedic
fractures, but outcomes are less predictable than with a Surgeons published their guideline and evidence report

r 2012 Lippincott Williams & Wilkins www.pedorthopaedics.com | S37


Narayanan and Phillips J Pediatr Orthop  Volume 32, Number 1 Supplement, June 2012

FIGURE 7. A and B, Nine-year-boy old who weighs 40 kg (88 lbs), with closed isolated low-energy injury. Long oblique fracture
shortened 3 cm and rotated. C, The patient was treated with a rigid trochanteric entry nail locked proximally and distally. He was
fully weight bearing by 7 weeks postoperatively and had a good result without evidence of proximal femoral growth disturbance
or avascular necrosis.

for the treatment of pediatric diaphyseal fractures.27 The 8. Irani RN, Nicholson JT, Chung SM. Long-term results in the
quality of the evidence available in current literature treatment of femoral-shaft fractures in young children by immediate
made it impossible to make strong recommendations spica immobilization. J Bone Joint Surg Am. 1976;58:945–951.
9. Buehler KC, Thompson JD, Sponseller PD, et al. A prospective
about any specific treatment. There is no single technique study of early spica casting outcomes in the treatment of femoral
that can be universally applied to all femoral shaft frac- shaft fractures in children. J Pediatr Orthop. 1995;15:30–35.
tures in children. Each of these methods has its own set of 10. Pollak AN, Cooperman DR, Thompson GH. Spica cast treatment
advantages and disadvantages and unique risk of com- of femoral shaft fractures in children—the prognostic value of the
mechanism of injury. J Trauma. 1994;37:223–229.
plications. Treatment strategy should be individualized to 11. Hughes BF, Sponseller PD, Thompson JD. Pediatric femur
the child with particular attention to the femur age and fractures: effects of spica cast treatment on family and community.
weight, his/her fracture characteristics, and the experience J Pediatr Orthop. 1995;15:457–460.
of the surgeon with a particular method. When >1 viable 12. Ligier JN, Metaizeau JP, Prévot J. Closed flexible medullary nailing
in pediatric traumatology. Chir Pediatr. 1983;24:383–385.
solution is available, it is important to include the parents 13. Metaizeau JP. Osteosynthesis of Children’s Fractures With Elastic
and child (when possible) in the decision-making process Stable Intramedullary Nailing. Montpellier: Sauramps Medical; 1988.
to take into consideration their preferences based on their 14. Ligier JN, Metaizeau JP, Prévot J, et al. Elastic stable intra-
individual judgments of the relative pros and cons of each medullary nailing of femoral shaft fractures in children. J Bone Joint
option. Surg Br. 1988;70-B:74–77.
15. Bar-On E, Sagiv S, Porat S. External fixation or flexible intra-
medullary nailing for femoral shaft fractures in children. J Bone
REFERENCES Joint Surg Br. 1997;79-B:975–978.
1. Hinton RY, Lincoln A, Crockett MM, et al. Fractures of the 16. Flynn JM, Hresko T, Reynolds RAK, et al. Titanium elastic nails
femoral shaft in children. Incidence, mechanisms, and sociodemo- for pediatric femur fractures: a multicenter study of early results
graphic risk factors. J Bone Joint Surg Am. 1999;81:500–509. with analysis of complications. J Pediatr Orthop. 2001;21:4–8.
2. Sanders JO, Browne RH, Mooney JF, et al. Treatment of femoral 17. Narayanan UG, Hyman JE, Wainwright AM, et al. The complica-
fractures in children by pediatric orthopedists: results of a 1998 tions of elastic stable intramedullary nail fixation of pediatric
survey. J Pediatr Orthop. 2001;21:436–441. femoral fractures, and how to avoid them. J Pediatr Orthop.
3. Wright JG. The treatment of femoral shaft fractures in children: a 2004;24:363–369.
systematic overview and critical appraisal of the literature. Can J 18. Sink EL, Gralla J, Repine M. Complications of pediatric femur
Surg. 2000;43:180–189. fractures treated with titanium elastic nails. J Pediatr Orthop.
4. Ferguson J, Nicol RO. Early spica treatment of pediatric femoral 2005;25:577–580.
shaft fractures. J Pediatr Orthop. 2000;20:189–192. 19. Ramseier LE, Janicki JA, Weir S, et al. Femoral fractures in
5. Czertak DJ, Hennrikus WL. The treatment of pediatric femur adolescents: a comparison of four methods of fixation. J Bone Joint
fractures with early 90-90 spica casting. J Pediatr Orthop. 1999; Surg Am. 2010;92:1122–1129.
19:229–232. 20. Moroz LA, Launay F, Kocher MS, et al. Titanium elastic nailing of
6. Sugi M, Cole WG. Early plaster treatment for fractures of fractures of the femur in children. Predictors of complications and
the femoral shaft in childhood. J Bone Joint Surg Br. 1987;69: poor outcome. J Bone Joint Surg Br. 2006;88:1361–1366.
743–745. 21. Caird MS, Mueller KA, Puryear A, et al. Compression plating of
7. Wright JG, Wang EEL, Owen JL, et al. Treatments for paedia- pediatric femoral shaft fractures. J Pediatr Orthop. 2003;23:448–452.
tric femoral fractures: a randomized trial. Lancet. 2005;365: 22. Jencikova-Celerin L, Phillips JH, Werk LN, et al. Flexible
1153–1158. interlocked nailing of paediatric femoral fractures: experience with

S38 | www.pedorthopaedics.com r 2012 Lippincott Williams & Wilkins


J Pediatr Orthop  Volume 32, Number 1 Supplement, June 2012 Femur Fracture Fixation in Children

a new interlocking intramedullary nail compared with other fixation 25. Blasier RD, Aronson J, Tursky EA. External fixation of pediatric
procedures. J Pediatr Orthop. 2008;28:864–873. femur fractures. J Pediatr Orthop. 1997;17:342–346.
23. Ağus¸ H, Kalenderer O, Eryanilmaz G, et al. Biological internal 26. Skaggs DL, Leet AI, Money MD, et al. Secondary fractures
fixation of comminuted femur shaft fractures by bridge plating in associated with external fixation in pediatric femur fractures.
children. J Pediatr Orthop. 2003;23:184–189. J Pediatr Orthop. 1999;19:582–586.
24. Sink EL, Hedequist D, Morgan SJ, et al. Results and technique of 27. Treatment of pediatric diaphyseal femur fractures: AAOS Guideline
unstable pediatric femoral fractures treated with submuscular bridge and evidence report. www.aaos.org/research/guidelines/PDFF
plating. J Pediatr Orthop. 2006;26:177–181. guideline.pdf. Accessed April 13, 2012.

r 2012 Lippincott Williams & Wilkins www.pedorthopaedics.com | S39

You might also like