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HR VISION BOARD

& EXECUTION PLAN


Slidexpress Conference Document
April 2021

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AGENDA
1. Koka Closure/Sell-out 3. TPO Savings
• Stock building • TRIM
• Product transfer • Insourcing
• Market Value Koka Properties
• Sellout Koka 4. Quality write off and Yield

2. Procurement Savings
• 2019 Execution Update
• API&Excipients
• Package
• 2020 Readiness
• API&Excipients
• Package

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cGAS/STING in Preclinical Inflammatory Models
Disease Animal model Proposed trigger Improved in STING KO?

Acute pancreatitis Cerulein model Unknown

Age-dependent macular degeneration Alu transcript induced RPE death Mitochondiral DNA

Alcoholic liver disease Chronic ALD model Unknown

Cancer DMBA-induced skin Nuclear DNA

- cancer model -

Liver fibrosis CCl4 administration -

Metastasis Distinct metastatic models Nuclear DNA

Myocardial infarction Permanent ligation model Extracellular DNA

Nonalcoholic MCD, HFD Mitochondrial DNA

steatohepatitis (NASH) - -

Parkinson’s disease Prkn–/–, Pink1–/– Mitochondrial DNA

- upon exercise and -

- Prkn–/–;mutator mice - -

Polyarthritis/fetal and Dnase2a–/– model Extracellular and nuclear DNA

neonatal anemia - -

Sepsis LPS shock model, cecal ligation Unknown

and puncture (CLP) model -


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Geographic prioritization

Key indicator 2018 2025 CAGR Indonesia-2018; Population: 266,357,297


10.0%
9.0%
Economy GDP (USD bn) 1,100 1,610 5.6% 8.0%
7.0%
6.0%
Population, m 266.4 284.5 0.8% 5.0%
4.0%
3.0%
2.0%
Urbanization 54% 60% 1.8% 1.0%
0.0%
0-4 5-9 10-14 15-19 20-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85-89 90-94 95-99 100+
Smartphone penetration 67% 89% 4.9% Male Female

Indonesia-2025; Population: 284,504,973


10.0%
 Very active demographics (vast majority of 9.0%
Indonesia’s population is young and strong 8.0%
KEY economic growth predicted) 7.0%

TAKEAWAYS 6.0%
5.0%
 Steady population growth and increased 4.0%
urbanization to drive consumer spending 3.0%
2.0%
1.0%
0.0%
0-4 5-9 10-14 15-19 20-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85-89 90-94 95-99 100+

Male Female

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Funnel approach for new businesses

Identify Incubate/Launch
• Research and explore • Discuss / negotiate with Grow & scale
specific opportunities relevant partner(s), • Develop strong
within key sectors including developing market position
across our Asian strategy, business plan,
markets financials, team, etc.
• Go to market with
consumers

Examples

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Who we are

100,000 + Ha
Farming land across
the world

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Institutional capital private equity

Impact of private equity on private company values Impact of private equity on private company values
Transaction Enterprise Value / EBITDA Billions of USD
For the years ended December 31, 2002-2018 For the period December 31, 2002-2018

Recessionary period Recessionary period


’02-’18 CAGR: 3.6% ’02-’18 CAGR: 11.6%
12.0x $4,000
$3,500
10.0x
$3,000
8.0x
$2,500
6.0x $2,000
$1,500
4.0x
$1,000
2.0x
$500
0.0x $0
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018

2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
Source: Standard and Poor’s Source: McKinsey & Co

Since 2002,private company valuations have increased substantially, primarily attributable to


fund managers driving competition, sophistication, organization and access to the asset class
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Three Pillars
Arterial Access Sampling Prep
Nurse

HCP in the specific workflow

Strategic partnership
Bard Vascular Access Collaboration
Physicians Co-marketing

HCP in their daily routine


HCP in their interaction with peers Sample Collection Sample Analysis

Respiratory Therapist

HCP in their interaction with other HCP roles Strategic partnership


In-house innovation
Co-marketing

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Indonesia supplier map

Zenlayer NDC Mitrakom Telkom Indonesia Biznet Salim Group/Keppel

Nex NTT Communications PT DCI Mitsui/Multipolar Technology JV ‹#›


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This industry shift to electric vehicles (EV) entails
opportunities and challenges for Canada to
navigate the rapidly evolving battery supply chain

Canada

Lots of relevant natural resources


Highly skilled workforce
for battery manufacturing

Strong international connections


Strong rule of law
and partnerships

Relatively low-cost input resources


(land, power, water)

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There is a higher-level perspective: An ecosystem […] this reaches SDS: a first
step from HW- provider to service provider
Emprises are transitioning from ‘Own & Operate’ to managed services

Past End state


Today: Transition phase
1. Buy HW/SW  Public, private, Hybrid Cloud
1. Buy managed services
2. Operate data […]  Energy aas/PATG offering 2. Everything automated
KPI: Price performance/ […] KPI: Price service need

Enterprises are moving toward


Everyone will move away from buy HW
managed, service offerings.
and licenses to paying bared on usage.
subscription bared whether you are in At the movement, CSP are the […] with […], The transition will take quite some time,
the cloud or on - premise - you don't and ISV realizing need to transform but that will be the end state
want to deal with IT operations anymore
CSPs Buy HW → sell service → highly profitable
Trust client enterprise architect , AT&T OERs Sell HW → moving toward service model […] VP/CTO cloud Oracle/CTO sales
Sell SW → moving toward service model leader, […]
ISV

In line with more trends,  needs to start  transformation with service provider

Past Transition – Step 1:SDS: End state

 Explore and understand customer needs(e.g. Use cases pricing)


 Explore and develop partnerships (e.g. OEMs, ISV, MSPs) Sell CPU times performance, […] […]
Sell CPU → one time revenue Successively transform into service provider
 revenue

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Overall transformation landscape: Key objectives of SDS needs to enter trial &
acceptance plan
Conceptual for
discussions

[…] and will always


Monitoring Market Standard Beginning Decommissioning
tell you that ‘aas’ is
growing the fastest
Accelerated Decommissioning what they often fail
to mention is that in
most cases at least
75-80% is still on-
a-a-s pricing hybrid
(Cloud
storage)
Concept introduction Trial & Acceptance Ma`rket
Growth → Market
Standard

Focus of SDSi […], VP cloud GE


Concept Trial & Market Health care, CPO
a-a-s Architecture,
Introduction Acceptance Growth
Other than IBM/CTO/CPO Vcloud
(Storage Air, […]
cloud)

2000 2010 2020 2030

Expect turnover Today NB: Transformation landscape will look


S: […] analysis different […] different market segments
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Solution proses

Accelerate Revenue/Profit
Modernise Our Core Scale New Business
Growth with digital

SG&A Efficiency Revenue/OI Increase Long Term Revenue/OI

Finance Customer Experience New Digital Businesses


 Eliminate/Standarise  eCommerce  JVs
 Shared Services  Digital Marketing  Livi
 ZBB  Analytics  Investments (M&A)
 RPA/NPL/ML/AI  Design thinking  Go Jek
HR  Mobile  Organically build
 Employee portal/experience  Mobile payment  Astra Digital
Procurement  Facial recognition  Digital G
 SS to optimise purchasing power  Loyalty  Speedworks
Revenue generation
IT
 BIM
 Cloud
 Modular Construction (DfMA)
 SaaS
 IOT
 Cyber
 Agile
 Mobile
 BYOD

Enablers Vision & Purpose Culture/Talent Capital Allocation KPIS

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THANK YOU

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