NAME:ID NO:

  THE UNIVERSITY OF LAHORE

  University Institute of Radiological Sciences And Medical
Imaging Technology
Fall Semester 2020

1 : An infant presents with an enlarged heart, muscle weakness, and

hypoventilation. She is diagnosed with glycogen storage disease type II, a
disease-causing, abnormal glycogen storage in the heart, skeletal muscle and
respiratory  muscles. Glycogen synthase is the regulatory enzyme for glycogen
synthesis. It adds glucose residues to the nonreducing ends of a glycogen primer
from:
A. Glucose-1-P
B. Glucose-6-P
C. UDP- Glucose
D. UTP
E. ATP

Answer: A (Glucose-1-p)

2: The steps of Glycolysis between glyceraldehyde 3phosphate and

3phosphoglycerate involve all of the following except:
A. ATP synthesis
B. Catalysis by phosphoglycerate kinase
C. Oxidation of NADH to NAD+
D. The formation of 1, 3- bisphosphoglycerate

Answer: C(oxidation of NADH to NAD+)

3: A 30- year-old male presents with severe muscle cramps. He is found to have
muscle glycogen phosphorylase deficiency(Mc Ardle’s disease, Glycogen
storage type 5).Glycogen phosphorylase degrades glycogen to produce:
A. Glucose
B. Glucose-1-P
C. Glucose-6-P
D. UDP Glucose
E. Glycogen Primer

Answer: B( Glucose-1-P)

4: Carbohydrates are organic compounds made up of:

 A. Carbon and hydrogen
B. Carbon hydrogen oxygen
C. Carbon hydrogen oxygen nitrogen
D. Carbon and oxygen
Answer: B carbon , hydrogen , oxygen

5: All of the following are monosaccharides except:

A. Glucose
B. Fructose
C. Maltose
D. Galactose

Answer: C (Maltose)

6: A 15-year-old  type 1 diabetic faints after injecting himself  with insulin. He
is administered Glucagon  and rapidly recovers consciousness. Glucagon
induces activity of:
A. Glycogen synthase
B. Glycogen phosphorylase
C. Glucokinase
D. Hexokinase
E. UDP Glucose pyrophosphorylase

Answer: B(glycogen phosphorylase)

7: After addition of pancreatic extract into a test tube with starch solution
disapperance of blue color in iodine test was observed. Under the action of
which pancreatic enzyme the starch is copletely hydrolyzed? 
A. Alpha Amylase
B. Chymotrypsin 
C. Lipase
D. Aldolase
E. Trypsin

Answer: A: alpha amylase

8: Two monosaccharides are joined by -------  bond:

A. Peptide
B. Phosphodiester
C. Glycosidic
D. Hydrogen

Answer:C (Glycosidic)
 9: Sucrose is a disaccharide made up of:
A. Glucose fructose
B. Glucose lactose
C. Glucose glucose
D. Glucose galactose

Answer: A glucose fructose

10: Unknown enzyme was added into two test tubes. The first tube contained
starch, the second one sucrose. After 10 min. incubation the solution in the first
tube gives the positive result for glucose, in the second one – negative. What
enzyme was added? 
A. lipase 
B. sucrose
C. amylase 
D. nuclease 
E. lactase

Answer: C (Amylase)

11: A newborn child had dyspepsia phenomena (diarrhea, vomiting) detected

after feeding with milk. After additional feeding with glucose the morbid
symptoms disappeared. The insufficient activity of what enzyme that takes part
in the carbohydrates breakdown causes the indicated disorders?
A. Saccharase
B. Amylase
C. Lactase
D. Isomaltase 
E. Maltase

Answer: c (Lactase)

12: Compounds with carbohydrates along with fatty acids are called:

A. Simple lipids
B. Waxes
C. Glycolipids
D. Phospholipids

Answer: C ( Glycolipids)

13: Dihyroxy acetone is a:
A. triose
 B. tetrose
C. pentose
D. hexose

Answer: A (triose)

14: Ptyalin breaks which of the following bonds:

A. alpha 1-2 bonds
B. beta 1-2 bonds
C. alpha 1-4 bonds
D. none of these
Answer: C (alpha-1-4 )

15: --------- endoglycosidase is absent in humans:

A. alpha1-4
B. beta1-4
C. alpha1-2
D. Beta1-2
Answer: B ( beta 1-4)
16: If carbohydrates are mirror images of each other they are:
A. Enantiomers 
B. Anomers 
C. Isomers 
D. epimers 

Answer: A(Enantiomers)

17: A 24year woman is getting training for her first marathon. Her coach
instructed her to keep a pace that allows her to stay below her anaerobic
threshold. Under such conditions pyruvate does not accumulate as it is
converted to:
A. Ethanol
B. Lactic acid
C. Acetyl co A
D. Alanine
E. Oxaloacetate

Answer: C (Acetyl co A)

18: A patient comes into clinic suffering from lack of energy and very low
hemoglobin levels. You run some tests and determine his red blood cells have a
high level of phosphoenolpyruvate with little pyruvate produced and decreased
 ATP levels. You quickly deduce that he has a mutation in which glycolytic
enzymes? 
A. Glyceraldehyde 3-phosphate dehydrogenase
B. Glucokinase 
C. Phosphofructokinase
D. Enolase
E. Pyruvate kinase

Answer: E (Pyruvate kinase)

19: If the ------ on anomeric carbon of a sugar is not attached to any other
structure the sugar is called reducing sugar:
A. Oxygen
B. Hydrogen
C. Hydroxyl
D. carbonyl

Answer: A (Oxygen)

20: A newborn is found to have fasting hypoglycemia. The nursery staff begins
overnight feeds by nasogastric tube because they find that the child consistently
has low blood glucose. A liver biopsy and molecular studies demonstrate an
absence of Glycogen synthetase.The normal function of this enzyme is to do
which of the followings ?
A. Remove glucose residues one at a time from glycogen in liver
B. Remove glucose residues one at a time from glycogen in muscles
C. Transfer UDP glucose to the non reducing end of glycogen primer
D. Hydrolyze Alpha 1,6 bonds of glycogen
E. Function as a glucosyl  transferase

Answer: C ( transfer UDP glucose to the non reducing end of glycogen

primer)

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