Schematic Diagram of Pathophysiology

Modifiable Factors: Non-Modifiable Factors:

-stress -decreased level of progesterone
-fatigue caused -aging pf placenta
overworking -oxytocin release
-strenuous works -prostaglandin cascade
-fetal adrenal maturation
-engagement of the presenting part

Onset of
Labor

Uterine contractions that result

to cervical dilatation

decidua produces prostaglandin

E2 and interleukin-8

increase in decrease increase in

uterine activity synthesis of production of
collagen MMP

PRETERM PREMATURE
RUPTURE OF MEMBRANES

Second Stage of Labor

(cardinal movements of the fetus)

 Third Stage
of Labor

active bleeding
Birth of infant separation and
expulsion of placenta

Postpartum

episiotomy level of hormones

uterus back
to pre- back to normal
pregnant
state
wound
healing systems back
mediate to normal
d by the
clotting
factors

Mother back to
pre-pregnant
state