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Intensive and Critical Care Nursing (2013) 29, 310—316

Available online at www.sciencedirect.com

journal homepage: www.elsevier.com/iccn

The experience of sleep deprivation in


intensive care patients: Findings from a
larger hermeneutic phenomenological study
Agness C. Tembo a,b,∗, Vicki Parker c,d, Isabel Higgins e,d

a
Casual Academic University of Newcastle, Newcastle, Australia
b
Registered Nurse Newcastle Private Hospital, New Lambton Heights, Australia
c
University of New England, Armidale, Australia
d
John Hunter Hospital, New Lambton Heights, Australia
e
University of Newcastle, Newcastle, Australia

Accepted 29 May 2013

KEYWORDS Summary Sleep deprivation in critically ill patients has been well documented for more than
Daily sedation 30 years. Despite the large body of literature, sleep deprivation remains a significant concern
interruption; in critically ill patients in intensive care unit (ICU). This paper discusses sleep deprivation in
Intensive care; critically ill patients as one of the main findings from a study that explored the lived experi-
Critical illness; ences of critically ill patients in ICU with daily sedation interruption (DSI). Twelve participants
Sleep; aged between 20 and 76 years with an ICU stay ranging from three to 36 days were recruited
Sleep deprivation from a 16 bed ICU in a large regional referral hospital in New South Wales (NSW), Australia. Par-
ticipants were intubated, mechanically ventilated and subjected to daily sedation interruption
during their critical illness in ICU. In-depth face to face interviews with the participants were
conducted at two weeks after discharge from ICU. A second interview was conducted with eight
participants six to eleven months later. Interviews were audio taped and transcribed. Data were
analysed thematically. ‘‘Longing for sleep’’ and ‘‘being tormented by nightmares’’ capture the
experiences and concerns of some of the participants. The findings suggest a need for models
of care that seek to support restful sleep and prevent or alleviate sleep deprivation and night-
mares. These models of care need to promote both quality and quantity of sleep in and beyond
ICU and identify patients suffering from sleep deprivation to make appropriate referrals for
treatment and support.
© 2013 Elsevier Ltd. All rights reserved.

∗ Corresponding author. Tel.: +61 4 03 5644125; fax: +61 2 49511592.


E-mail addresses: Agness.Tembo@gmail.com, Agness.Tembo@newcastle.edu.au (A.C. Tembo).

0964-3397/$ — see front matter © 2013 Elsevier Ltd. All rights reserved.
http://dx.doi.org/10.1016/j.iccn.2013.05.003
The experience of sleep deprivation in intensive care patients 311

Implications for Clinical Practice

• Clinicians need to recognise and promote the importance of sleep for patients in ICU.
• Practices that shield patients from witnessing death in ICU are needed.
• Models of care that seek to prevent and alleviate sleep disturbances in and beyond ICU are needed to promote both
quality and quantity of sleep in and beyond ICU.

Introduction also found that the intervention group had a shorter length
of stay (LOS) in ICU as compared to the control group.
However, there was no significant difference in the health
Sleep deprivation is characterised by continued lack of
related quality of life between the two groups. This study
restorative sleep over time that results in physical and cog-
however, was a single centre study with a small number of
nitive sequlae (Fulke and Vauqhan, 2009). Sleep deprivation
patients. The impact of DSI on sleep however, was also not
in critically ill patients has been well documented for more
established.
than 30 years (Hardin, 2009) and contributing factors and
Sleep deprivation is renowned for causing disorders
therapeutic approaches to alleviate sleep deprivation have
of the mind (Germain and Zadra, 2009; Ramful, 2006;
been researched extensively (Friese, 2008; Hardin, 2009;
Simon, 2009), including delirium (Friese, 2008; Tembo
Tembo and Parker, 2009).
and Parker, 2009). The consequences of sleep depri-
Noise, pain and discomfort (Hardin, 2009; Pandharipande
vation include impaired immunity, protein catabolism,
and Ely, 2006; Reishtein, 2005) as well as modes of ventila-
deranged host defenses and death (Friese et al.,
tion, and many drugs used in ICU are among the possible
2009; Pandharipande and Ely, 2006; Parthasarathy and
causes of sleep deprivation in critically ill patients (Friese,
Tobin, 2004). Of concern in ICU is that sleep depriva-
2008; Parthasarathy and Tobin, 2004; Tembo and Parker,
tion weakens upper airway muscles causing respiratory
2009). The administration of sedatives and analgesics by a
problems including a prolonged need for ventilator
continuous infusion has been the mainstay of drug treat-
support, ICU stay and it complicates the post extu-
ment for managing patients requiring mechanical ventilation
bation period (Friese, 2008; Parthasarathy and Tobin,
in ICU for many years (Kress et al., 2002; Ogundele and
2004).
Yende, 2010). Continuous sedation and analgesia are used
Unfortunately, the many causes of sleep deprivation
largely for the patient’s comfort, to improve patient and
pose a challenge to its treatment, prevention and allevi-
ventilator interactions, decrease pain and anxiety, and
ation (Tembo and Parker, 2009). Whilst measures such as
self-injury (Ogundele and Yende, 2010). The cumulative
diurnal lighting (Honkus, 2003), noise reduction (Stracham
effects of sedation and analgesia however, may delay the
and Brown, 2004), careful choice of mechanical ventilation
patient’s withdrawal from mechanical ventilation support
modes (Friese, 2008; Tembo and Parker, 2009) and clus-
(Kress et al., 2002). The effects of continuous sedation for
tering of nursing care (Tamburi, 2004; Tembo and Parker,
ventilation is known to extend ICU stay, and increase the risk
2009), have been recommended to prevent and/or allevi-
of complications associated with ventilation, delirium and
ate sleep deprivation in ICU, patients continue to suffer.
post-traumatic stress disorder (PTSD) (Ogundele and Yende,
It is argued that the causes may be the critical illness
2010). Daily sedation interruption (DSI), whereby patients
itself (Tembo and Parker, 2009) and/or the medications
are administered intermittent boluses of sedatives, seeks to
used for sedation and analgesia (Pandharipande and Ely,
alleviate these problems (Kress et al., 2003), however its
2006).
long term effects and the impact on the patient are largely
Whilst it is well known that sleep is essential for
unexplored. Debate over the use of one mode over the other
healing, recovery and surviving critical illness (Richardson
in terms of the benefits to patients, is unresolved (Kress
et al., 2007; Stracham and Brown, 2004; Tamburri et al.,
et al., 2002).
2004) sleep deprivation in critical illness survivors contin-
A study by Kress et al. (2003) however, provides some
ues to be a problem. Of concern, is that the experiences
insight. Kress et al. (2003) conducted a comparative study
of sleep deprivation for the sufferers have not been
of DSI and continuous infusion in order to establish whether
explored. This paper shares the experiences of people with
DSI was associated with long term psychological harm and
sleep deprivation who were participants in a study that
to measure outcomes such as post traumatic stress disorder
explored the experiences of being critically ill in ICU with
(PTSD). The researchers compared psychological outcomes
DSI.
of ICU patients (n = 13) undergoing DSI (intervention) to
those (n = 19) who underwent continuous sedation infusion
(controls). Participants included patients who were admit-
ted to ICU for sedation and mechanical ventilation. A range
of measures were used including those for PTSD, health sta-
tus, anxiety, depression and psychological adjustment to Aim of the study
illness. Participants were interviewed at least six months
after discharge from ICU. Findings suggested that DSI did The aim of the study was to describe the experience of
not result in psychological harm. Patients in the interven- critical illness in ICU with DSI and how this impacted the
tion group fared better for PTSD than the controls. They participants’ continued existence.
312 A.C. Tembo et al.

Research question Setting description

The research question was: What is the experience of critical The study was conducted in a 22 bed ICU of a tertiary refer-
illness in the context of DSI and how does it affect people’s ral teaching hospital in the state of New South Wales (NSW)
lives after discharge? in Australia, which treats a variety of patients ranging from
The following questions guided the inquiry; what does it infants to older people. It is a multidisciplinary unit that
mean to have been critically ill in ICU with DSI, what is it treats all types of injuries and illnesses, and provides post-
like to be critically ill and mechanically ventilated with DSI, operative care to patients following major surgery including
what is it like to wake up from a state of unconsciousness head and neurosurgery. It has a helicopter retrieval service
in ICU and what is the impact of critical illness and ICU on that transports critically ill patients from smaller hospitals
continued existence? within the radius of 500Km and also transports patients
to specialist treatment in the metropolitan hospitals of
Sydney. Mechanically ventilated patients are nursed on a
ratio of one to one with other less critical patients nursed
Methods on a one to two ratio.

Research design Recruitment of participants


This study used a qualitative design guided by phenomen- Participants were purposively recruited on the basis of hav-
ology as the research methodology. Phenomenology aims ing had the experience of being critically ill in ICU. To be
to gain deep understanding of the meaning of everyday eligible to participate in the study participants had to have
experiences (Van Manen, 1990). Unlike other sciences, phen- been ventilated for at least 48 hours and to have undergone
omenology seeks to garner insightful descriptions of the DSI. They had to be 18 years and over, English speaking,
way the world is experienced pre-reflectively without tax- without any cognitive impairment and able to give informed
onomising, abstracting or classifying it (Van Manen, 1990). consent. Participants were initially approached by a third
Phenomenological research aims at describing and under- party who informed them of the study and gave them the
standing human experience (Van Manen, 1990) and allows researcher’s contact details. Twelve people agreed to be
researchers to explore the depths of experience and the interviewed. Table 1 below shows the description and demo-
associated meanings. graphic data of the participants. Pseudonyms were used to
protect the participants’ identity.
To understand people’s experience we . . . need to get
really close to them so that their hopes become our Data collection
hopes, their pain becomes our pain—we . . . need to
listen and speak, read and write in a manner that is
Data collection included in-depth face to face interviews
attentive to the things of the world that are ultimately
with participants. An interview guide was used with open
unnamable.
ended questions designed to explore experiences. For exam-
ple, participants were asked ‘‘Can you tell me about what
Manen (1999, p. 19) it was like for you when you were in ICU’’? Participants

Table 1 Summary of demographic and other relevant data.

Participant Age Reason for admission LOS in ICU (days) Period of


mechanical
ventilation (Days)

Keith 76 Cardiac event 36 27


Jason 69 Haemothorax 4 3
George 58 Chest infection 4 3
Rosie 34 severe metabolic 3 2
acidosis
Ian 56 Metabolic diabetic keto 6 5
acidosis
Moira 76 Triple Vessel CABG 10 8
Alex 65 Aortic bifemoral bypass 9 5
Kate 60 Cardiac arrest. 13 11
Aspiration pneumonitis
Eric 20 Traumatic chest injury 6 5
Maggie 23 Status epilepticus 6 4
Liam 71 Major abdominal surgery 3 2
Monika 41 Motor vehicle accident 6 4
The experience of sleep deprivation in intensive care patients 313

were interviewed two weeks after they had been discharged along with the process of recruitment. The experiences,
from ICU and again six to eleven months later. A total opinions and perspectives of participants in this study
of 24 interviews were conducted. Four participants were are represented by the exemplars provided to support
interviewed once; two of them declined the subsequent their descriptions of disturbed sleep. Only people who had
interview, one could not be interviewed because of ill health experienced critical illness with DSI were approached to par-
and one could not be contacted. The remaining partici- ticipate in the study. Purposive sampling ensured there was
pants were interviewed twice. Interviews were conducted representation of the experience under study. In depth face
in participants’ homes or place of preference where pri- to face interviews were held with all of the participants in
vacy, safety and comfort were ensured. Interviews were order to ensure thick description of experiences. Preliminary
between 30 to an hour and 45 minutes. During interviews the data analysis was conducted by the lead author and verified
researcher recorded notes of the participants’ non-verbal by authors one and two who have experience in ICU and
cues observed. Data saturation was deemed when no new qualitative research. Consistent with qualitative research,
information was obtained from interviews. All interviews the researchers used a process of reflexivity throughout;
were audio recorded and later transcribed for analysis. assumptions, preconceptions, and beliefs relating to the
study were identified, monitored throughout, recorded and
discussed as the data were analysed. Sleep deprivation was
Data analysis
a major concern of 8 of the 12 participants in this study
A selective highlighting approach was used to analyse the
transcribed interviews (Van Manen, 1990). This approach Ethical Considerations
meant that the researcher looked for phrases and sentences
that were exemplars of the lived experience of critical ill- Ethical approval was sought and granted in December, 2007
ness in ICU. Data analysis began as soon as data collection by the Research Ethics Committee where the study was
commenced. The process of analysing individual transcripts undertaken. Potential participants were given both written
helped the researcher to guide the subsequent interviews and verbal information about the study. Written consent was
while keeping in mind the original research questions. obtained from participants.
Significant phrases and sentences relating to the study ques-
tions were highlighted, clustered, categorised and emergent Findings
themes identified. Having conducted the interviews and the
preliminary data analysis of each transcript, the researcher The experience of being critically ill in ICU in the context of
then used a ‘‘parts and whole’’ process whereby highlighted DSI was depicted in this study as ‘‘being in limbo’’. Being
phrases and sentences were compared and contrasted across in limbo, the essential feature of the experience of the
all of the transcripts and identifying recurrent ideas and participants in this study, exemplifies the uncertainties the
themes from individual transcripts. Emergent themes and participants faced during this time. In this paper we present
subthemes allowed the researcher to demonstrate and bring selected findings from the study to highlight the concerns
to light the various differences, contradictions and tensions of participants in relation to sleep captured in the themes
that characterised the participants’ experiences. Linguistic ‘‘Longing for normal sleep’’ and ‘Being tormented by night-
data was then transformed into phenomenological sensitive mares’. Here they described not being able to sleep and
text through the process of writing, reflection and rewriting. having nightmares reminiscent of their stay in ICU and that
Constructing linguistic transformation of data is a challeng- kept them awake throughout the night. They longed for
ing creative hermeneutic process (Van Manen, 1990) that the return of peaceful sleep. The findings relating to other
involved generating text and forming paragraphs from the themes in this study will be reported elsewhere.
data and the researcher’s notes of non-verbal cues obser-
vations of the participants. During the analysis, consistent
with the study aims and research questions, attention was
Longing for normal sleep
given not only to the participants’ experiences more broadly
within the context of ICU, DSI and beyond but also to the ‘‘You just doze on and off if you’re lucky. And back then
impact on the participants lives. Sleep deprivations emerged ah I’d sleep for a couple of hours and wake up. Once I
as a major concern for many (n = 8) of the participants as woke up, I knew that was the end of the night’s sleep.
described in the findings below. It might be 11 o’clock, 12 o’clock or whatever, I knew
I wasn’t going to get anymore sleep that night. And you
Credibility and rigour just lay there all night—for the rest of the night. You knew
what was going on around you all the time and think ‘oh
Phenomenology attends to matters of credibility by 1 o’clock, 2 o’clock, 3 o’clock, 4 o’clock all awake, all
describing the study population, selection procedures for the time I just couldn’t sleep of a night time. I lay awake
participants and ensuring an accurate representation of all night—hour after hour. Ah, it was—oh, I was getting
the participants’ experiences, opinions and perspectives desperate to get a night’s sleep. I don’t know why. I’m
(Gerrish and Lacey, 2010; Moustakas, 1994). Phenomeno- still the same here. I wake up at 11 or 12 o’clock, that’s
logical research is also judged by the evocativeness and it.’’
transferability of the experience, and the accuracy of rep- (Keith 1st Int.)
resentation (Van Manen, 1990). In relation to the findings Participants were desperate for sleep. So desperate were
reported here the study population has been described they that some took sleeping tablets against advice. The
314 A.C. Tembo et al.

sleeping tablets proved to be futile in achieving a good ‘‘I wake up distressed in the middle of the night and a lot
night’s sleep. Most of the participants attributed their of that’s got to do with, I don’t know what’s real and what
inability to sleep to the medications they had in ICU and the isn’t. So I have to ask Joseph, did that really happen? Did
medications they were using at home. Participants searched they really do those things to me or am I imagining it? And
for reasons for their inability to sleep. he’ll either confirm or deny what actually happened to
me because I’m not sure. So, it is left you know, I don’t
‘‘No reason why [the lack of sleep] whether it was the
sleep well yet.//. I expect that it will get better.’’
medication or the surroundings or what it was, I just
(Rosie 1st Int.)
couldn’t get back to sleep. I just couldn’t.//. Like last
night I think I woke up about half past 12 or something like Six months after ICU, Eric was still traumatised by his
that.//. Same thing, even when I took sleeping tablets. . . ICU experiences relived every night through nightmares Eric,
I was told I shouldn’t be taking them.//. I so desperately like Rosie, hovered between the world of ICU and the famil-
want to sleep. It becomes annoying. And you don’t know iar world of home and mainstream life. Eric also depended
why. You can’t understand it..//. One day I’ll get back to on his wife to put things in perspective — regaining his orien-
a normal nice sleep.’’ tation to the real world of that time. The silence of the night
(Keith 1st Int.) was relentless and frightening for Eric. It took him back to
Jason reasoned that he ‘‘had his eyes closed for five the sounds of the monitors he endured when he was in ICU.
days’’. For Eric there may be no moving on from ICU:

‘‘I can’t sleep.’.//. I don’t know why? I just can’t go to ‘‘They come in the dreams and I’m waking up with the
sleep. I don’t know whether it was that I probably did tubes and being tied to the bed. That’s lack of sleep, I
close my eyes and I had my eyes closed for five days.’’ don’t sleep much, I keep waking up, tossing and turning
(Jason, 1st Int.) and getting up through the night.//. I’ll feel like I’m tied
George said: down and they’ve got tubes in my mouth and just could
be waking up out of a dream and it just freaks me out. I
‘‘I can’t sleep. I don’t know why I just can’t go to sleep. I still remember hearing noises. I’ll be asleep and when it’s
want to but I don’t know whether it is that I did close my real quiet I can hear the sounds of the monitors going off,
eyes and I had my eyes closed for five days..but I hope I beep and beep beep. That sort of starts to freak me out a
will be able to sleep like I used to again.’’ bit, ‘because I have the feeling of back in hospital.//. My
Mrs. being next to me, she’s had to calm me down saying,
Some participants could not sleep because people were
‘You’re right. You’re at home. You’re not in hospital.’ I
dying and they thought they were also at risk. They were
just freak right out.//. I don’t know when all this will
frightened to go to sleep in a place where death was per-
end.’’
vasive, as Ian said; ‘‘I couldn’t sleep because the people
(Eric 2nd Int.)
around me were basically dying’’. For Ian sleeping reminded
him of being ‘‘blacked out’’ with DSI in ICU and where death As the experiences of sleep deprivation continued the
may have taken him. Seeing others dying made him sense his participants became desperate for sleep as Keith said:
own death more profoundly. Yet when he thought he had left
death behind in ICU and he was in the comfort of his own ‘‘I am so desperately wanting to sleep and you can’t and
home and bed, he found that he still could not sleep. The the more you try, the less chance you’ve got. It becomes
only means of survival was to stay awake and keep vigil so annoying. Ah, you’d be dead tired but you can’t get to
that death did not claim them. This was also described by sleep. And you don’t know why. You can’t understand it.’’
Kate: (Keith, 1st Int.)
‘‘There was one night a doctor’s husband died. He had a
Moira could not sleep because she continued to experi-
heart attack, they rushed him in. The whole place was
ence nightmares;
erratic, you know and I hardly slept at all that night. I
slept for a few hours and then I’d wake up.//. I couldn’t
‘‘I still can’t sleep because I still have bad nightmares
sleep in that place because everybody around me was
after all this time and I don’t think I should.’’
dying.’’
(Kate, 1st Int.) The participants in this study described living without
sleep as punctuated with nightmares and the troubling expe-
Being tormented by nightmares riences of their critical illness and ICU stay. Life in ICU was
characterised by the expectation that one day, they would
Rosie’s sleep times were filled with nightmares about her be able to sleep restfully. As Kate said;
ICU experience and often she would wake up with beads
of perspiration, unsure where she was. She would ask her ‘‘So, it is left you know, I don’t sleep well yet.//. I expect
partner to clarify the nightmares as to whether or not they that it will get better. But at the moment, I don’t sleep
really happened. Rosie’s world changed between night and very well. I have a lot of night sweats and wake up not
day. At night during sleep, nightmares returned her to the quite sure where I am.’ One day I’ll get back to a normal
dark and horrifying world of ICU. During the day she was nice sleep..//.Till then I remain in limbo not knowing
safe and in control with a hold on the world and things that when all this will end.’’
mattered to her. Rosie explains: (Kate, 1st Int.)
The experience of sleep deprivation in intensive care patients 315

Discussion collection and it analysis. The findings, therefore, represent


the researcher’s account and interpretation of the raw data.
For the participants in this study there were some who There may be other interpretations that are equally valid.
did not report concerns about sleep, however there were The themes identified are the researchers’ interpretation
several others who were clearly troubled by their inability of the participants’ experiences and guided by their under-
to sleep. They could not understand why sleep eluded them standing of phenomenology. Therefore throughout the study,
and were desperate to overcome this. Others experienced the researchers endeavoured to maintain trustworthiness
disrupted sleep with terrifying dreams and nightmares. of the findings by emphasising the individuality of the par-
These participants shared a longing for peaceful sleep. ticipants’ situation through which they revealed the varied
Sleep was seen to some extent as both a means to and a experiences of each one of them. Emphasising the individu-
symbol of their recovery. Without sleep they were unable ality and situations resonate with Merleau-Ponty’s argument
to resume their lives. Some were afraid to sleep because that man is ‘always situated and individuated’ (Merleau-
of recurring nightmares; they were constantly tired, often Ponty, 1964, p. 51). It is also a limitation in that what is
depressed and unable to feel safe in the world. That they understood is based only on the individual’s perception at
could not sleep and experienced ongoing nightmares that that particular time. Whatever follows is not known.
depicted scenes of their ICU experiences disallowed their
ability to move on with their lives. In the absence of Conclusion
peaceful sleep they were living life in limbo.
The participants’ descriptions of sleep deprivation have The study demonstrates patients continue to experience
revealed the negative effects of critical illness in ICU with sleep deprivation at various stages of their trajectory of crit-
DSI and the struggle participants engaged in to regain ical illness in and beyond ICU. The findings suggest a need for
restorative sleep. The findings presented here show that the models of care that seek to support restful sleep and pre-
absence of sleep was distressing for participants and that vent or alleviate sleep deprivation and nightmares. These
nightmares impacted the ability and quality of their sleep. models of care need to promote both quality and quantity
Some participants described a heightened sense of death as of sleep in and beyond ICU and identify patients suffering
a reason not to sleep in ICU and on return to home: they felt from sleep deprivation. Clinicians need to be mindful of
the proximity of their own death, they feared not waking the role of comfort in promoting sleep, including the use
from sleep, and they were witness to the death of others in of comfortable beds, judicious repositioning procedures and
ICU. This finding has been reported by others (Parker, 1997; communicating with patients regarding their comfort needs
Rattray et al., 2004; Zeilani and Seymour, 2010). That night- and preferences for sleep and rest. Practices that shield
mares constantly took participants back to their ICU expe- patients from witnessing death in ICU are needed.
riences has also been found in other studies (Ringdal et al., Both nurses and students need to be educated about the
2006; Roberts et al., 2006; Roberts and Chaboyer, 2004). importance of sleep, factors that impact on it and the com-
Although other studies have described the effects of criti- plications that arise from sleep deprivation in ICU patients
cal illness and ICU hospitalisation for patients, these descrip- with the aim that they can observe policies that could sup-
tions have been interpreted largely as PTSD arising from the port and improve patients’ sleep in and beyond ICU. In
trauma associated with being ventilated and receiving seda- service for new nursing staff and other medical personnel
tion. Accounts of nightmares and sleepless nights after ICU could shed insight and understanding that would result in
have been described since the early days of ICU (Blachly and better sleep patterns for the patients.
Starr, 1964; Kornfeld et al., 1969). The findings of this study, Future research needs to address ways of promoting rest-
however, provide insight into the impact of the experience ful sleep amongst critically ill patients. A range of strategies
for survivors highlighting both uncertainty and vulnerability need to be explored with a particular focus on those that
and the need to reconsider models of care that address the promote quality/depth and length of sleep both during and
problem of sleep across the critical illness trajectory. after ICU. Research into drugs that that do not interfere with
Models of care might include follow-up pathways with patients’ quality and quantity of sleep and those that help
attention to psychological support for nightmares, promot- patients to sleep as naturally as possible could be helpful.
ing sleep hygiene or rehabilitation and sleep clinics. These
models of care need to promote both quality and quantity
of sleep in and beyond ICU and might be achieved through
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