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Facial Resur facing

of the Male Patient


Samuel O. Poore, MD, PhDa, Liat Shama, MDb,
Benjamin Marcus, MDb,*

KEYWORDS
 Facial aging  Ablative skin resurfacing
 Nonablative skin resurfacing

The most common cosmetic facial plastic proce- present to a cosmetic surgeon, they are usually
dures sought by men include Botox injections, less familiar with the medical system and therefore
hair transplants, filler injections, chemical peels, less comfortable discussing procedures. Addition-
rhinoplasty, and microdermabrasion (Fig. 1). The ally, having spent less time in the medical system,
American Society of Plastic Surgeons (ASPS) they may not be aware of the downtime that is
recently reported a 43% increase in nonsurgical associated with the procedure that best
procedures in men over the past 5 years. From addresses their concerns. Men generally present
2002 to 2003 the number of minimally invasive for cosmetic procedures at a later age than women
procedures performed on men jumped 41%. The and have usually engaged in behaviors that pre-
dramatic increase in the number of nonsurgical dispose them to seeking cosmetic surgery, such
procedures per year, which continues to surpass as not wearing sunscreen and smoking.3
surgical procedures, is likely attributable to an Men do not usually wear cosmetics, and there-
increase in disposable income in the baby-boomer fore are more concerned about the postprocedure
generation and the increased acceptability of cos- downtime, as they may prefer not to have recog-
metic procedures that has led to an increase in nizable sequela of healing from a cosmetic proce-
male patients seeking cosmetic procedures. dure.4 This may explain why cosmetic nonsurgical
These statistics clearly reflect that what was procedures, including Botox and microdermabra-
once a field embraced primarily by females has sion, have increased among the male demo-
now become accepted and firmly rooted in the graphic by more than 300% and 400%,
male demographic.1,2 respectively, since 2000. These nonsurgical
procedures have minimal downtime and are
OVERVIEW OF THE MALE PATIENT more acceptable to the male demographic.1,3
Despite this greater acceptance of men seeking Additional data from the American Academy of
and obtaining cosmetic surgery, a desire for Facial Plastic and Reconstructive Surgery and
discretion plays a significant part in the type of American Society of Aesthetic Plastic Surgery
cosmetic enhancement or surgery that men select. show an upward trend for men in Botox and hair
Men come to cosmetic surgeons and dermatolo- restoration with respect to other procedures,
gists for many of the same issues, concerns, and which have remained relatively stable or
problems as women, but cite different reasons. decreased. These data indicate that the largely
Women want to ‘‘look less tired’’ or ‘‘look better,’’ untapped and growing market for cosmetic
whereas men indicate work-related reasons for enhancement for men lies in the realm of nonsurgi-
seeking cosmetic surgery; they want to ‘‘increase cal procedures. Skin resurfacing encompasses
competitiveness’’ in the workplace.2 When men most nonsurgical procedures.
facialplastic.theclinics.com

a
Division of Plastic and Reconstructive Surgery, University of Wisconsin, 600 Highland Avenue, CSC G5/361,
Madison, Wisconsin, USA
b
Division of Otolaryngology—Head and Neck Surgery, University of Wisconsin, 600 Highland Avenue,
CSC K4/720, Madison, Wisconsin, USA
* Corresponding author.
E-mail address: marcus@surgery.wisc.edu (B. Marcus).

Facial Plast Surg Clin N Am 16 (2008) 357–369


doi:10.1016/j.fsc.2008.04.001
1064-7406/08/$ – see front matter ª 2008 Elsevier Inc. All rights reserved.
358 Poore et al

Top Nonsurgical Cosmetic Procedures Fig. 1. Top nonsurgical cosmetic pro-


cedures performed in 2003 in the
In 2003, 78% of the nearly 8.3 million cosmetic procedures performed in the
United States. (Courtesy of The
USA were nonsurgical. Most popular nonsurgical procedures:
American Society of Aesthetic Plastic
2,272,080 Botox Injection Surgeons, Los Alamitos, CA.)

923,200 Laser Hair Removal

858,312 Microdermabrasion

722,248 Chemical Peel

620,476 Collagen Injection

Source: American Society for Aesthetic Plastic Surgery

THE AGING FACE analysis before any resurfacing procedure should


follow similar partitioning (Box 2). Included in this
A man finds room in a few square inches of his is determining each patient’s Fitzpatrick classifica-
face for traits of all his ancestors; for the tion, which helps guide treatment, predicts side
expression of all his history, and his wants. effects, and helps identify individuals who should
—Ralph Waldo Emerson not receive resurfacing at all (Box 3). There are
The aging face presents a complex picture to additional characteristic soft tissue changes in
facial plastic surgeons because it reflects multifac- the face as described by Patipa.8 According to
torial and additive causes, including sun exposure, this author the face should be analyzed by subdi-
tobacco use, and a lifetime of facial expression. viding the face into thirds and noting changes in
There are two types of skin aging. The first is chro- each subdivision accordingly (Fig. 2). Complete
nologic aging (intrinsic aging), which occurs in all facial rejuvenation requires improving volumetric
areas of the skin. The second is photoaging and cutaneous age-related changes. Skin resur-
(extrinsic), which occurs in skin areas including facing therefore plays a key role in the facial plastic
the neck, face, and hands. Photoaging results in surgeon’s armamentarium for male rejuvenation.
rough skin, sallow color, uneven pigmentation,
and fine and course wrinkling.5 These intrinsic
Box 1
and extrinsic factors leads to dyschromias of the Clinical and histologic effects of aging
skin, fine wrinkles, loss of collagen, and thinning
of the skin.6 Rhytidosis and skin laxity are the Clinical appearance of photoaging
primary issues surrounding the aging face. Rhyti- Fine and coarse wrinkling
dosis, including fine lines and wrinkles, may be ad-
Rough texture
dressed by several nonsurgical modalities,
including fractional skin resurfacing, plasma skin Sallowness or yellow color
resurfacing (PSR), Coblation, dermabrasion, and Uneven pigmentation (lentigines, melasma,
chemical peels. ephelides)
The pathogenesis of the aging face includes loss Leathery appearance
of the reticular dermis and reduction of overall der-
mal organization. Specifically, Type I collagen, the Laxity
most abundant type in the non-aged face, is Histologic effects of photoaging
replaced with Type III collagen as the dominant
type.7 The hallmark of actinically damaged skin Epidermal atrophy
(damage caused by UVB and UVA rays) consists Decreased collagen content
of thickened, degraded elastic fibers. Based on Elastosis
multiple studies there seem to be three types of
Cellular atypia
wrinkles: (1) animation creases from mimetic mus-
cle insertions, (2) fine, shallow wrinkles caused by Preneoplastic dysplasia (actinic keratoses)
disruption of the elastic structural network, and (3) Decreased microcirculation
coarse, deep, solar wrinkles.5 The clinical and
Data from Boswell CB. Skincare science: update on
histologic effects of aging are summarized in topical retinoids. Aesthetic Surgery Journal
Box 1. Changes in the aging face can be catego- 2006;26:233–9.
rized into specific anatomic subunits and facial
Facial Resurfacing of the Male Patient 359

Box 2
Skin and soft tissue changes of the face associated
with aging

Perioral changes
Vertical rhytides
Decreased fullness and flattening of the up-
per lip
Downturning of the oral commissures
Deepening of the nasolabial creases (mario-
nette lines)

Cervical changes
Skin laxity and wrinkling
Vertical platysmal bands
More obtuse cervicomental angle
Ptosis of the submandibular glands

Periocular changes
Fig. 2. The three zones of facial aging.
Dermatochalasis: laxity of the skin of the
eyelids
ABLATIVE AND NONABLATIVE SKIN RESURFACING
Excessive eyelid edema and pigmentation
Protrusion of the periorbital fat Techniques in skin resurfacing that address the
aging face, acne, and disorders of vascularity
Ptosis of the lacrimal glands
and pigmentation include ablative and nonablative
Facial skeletal changes modalities. Methods of ablative skin resurfacing
involve superficial penetration of skin with necrosis
Decreased mid and lower facial height of the epidermis leading to removal of the epider-
Laxity of support ligaments mis and superficial thermal damage within the
Increased chin prominence dermis. This dermal damage leads to collagen
denaturation and contraction of the tissue and as
Increased prominence of the supraorbital
rim the entire epidermis is vaporized, there is resulting
erythema, which can last several months.6 Hypo-
Increased prominence of the zygomatic arch pigmentation may also occur. Despite the drastic
outcomes of ablative skin resurfacing, its longer
healing process makes it less desirable than non-
ablative skin resurfacing, particularly in patients
Box 3 who desire improved cosmesis while maintaining
Fitzpatrick skin types discretion and anonymity. The unwanted side
Type I: White, always burns and never tans effects of ablative procedures ultimately lead to
a longer downtime and healing process, and
Type II: White, always burns and sometimes tans when the pressures of quickly returning to work
Type III: White, sometimes burns and sometimes and the desired anonymity of having a cosmetic
tans procedure are taken into account, ablative tech-
Type IV: Light brown, minimal burns and gradu- nologies have decreased in popularity among
ally tans both male and female patients. This shift in popu-
Type V: Brown, never burns and tans to deep larity is exemplified by the once gold standard
brown carbon dioxide laser modality.9
Nonablative skin resurfacing involves deeper
Type VI: Black, never burns and deeply tans
skin penetration with selective thermal damage
All patients should receive posttreatment sunscreen. to the dermis, effectively sparing the epidermis
Type IV requires pre- and posttreatment with retinoic with some laser models and minimally affecting
acid, hydroquinone, and sunscreens to decrease risk
for pigmentary changes. TCA better for types IV and
the epidermis with other models.10 Methods of
above. Types V and VI, avoid resurfacing if possible. nonablative skin resurfacing include mid-infrared
lasers, radiofrequency devices, pulsed dye lasers,
360 Poore et al

intense pulsed light, photodynamic therapy, Ultrapulse CO2 laser (UPCO2, Coherent) is the
fractionated laser modalities, and plasma skin most commonly used of the ultrapulse CO2
regeneration. There is significant overlap between lasers.18 It maximizes the benefits of CO2 lasers
indications for these various applications, includ- while minimizing damage to the surrounding struc-
ing rhytidosis, actinic keratosis, telangiectasias, tures. As with other methods of facial resurfacing,
and hyperpigmentation (Fig. 3).11 Some of the patients are carefully selected for CO2 laser resur-
side effects of nonablative resurfacing include facing; the ideal candidates for CO2 laser resurfac-
discomfort, sunburnlike erythema, edema, and ing are those who have Fitzpatrick I to II skin types
flaking. The erythema and flaking may last up to and realistic expectations of the procedure.19,20
one week.12 Patients who have Fitzpatrick skin types III and
above are at higher risk for pigmentation-related
ABLATIVE SKIN RESURFACING complications from ablative procedures.19,21,22
Carbon Dioxide Laser CO2 laser resurfacing is performed as an outpa-
tient procedure. Local anesthetic, either topically
CO2 laser resurfacing, developed in 1964, has until or by direct infiltration and nerve blocks, is
recently been regarded as the gold standard of commonly used. For full face resurfacing, intrave-
ablative facial resurfacing.13 Initially used in nous sedation is often used also.13,19 The number
a continuous wave, it produces a beam with of passes performed depends on the desired out-
a wavelength of 10,600 nm. Water, present mostly come. The first pass ablates the epidermis, leading
in the epidermis, is its primary chromophore.13 The to an effect profile and recovery period similar to
first pass ablates the epidermis; subsequent treatment with multiple passes with the erbium:-
passes ablate the dermis, which is limited by the yttrium-aluminum-garnet (erbium:YAG) laser.23
lower water content of the dermis. These subse- Subsequent passes are carefully applied, with
quent passes lead to collagen shrinkage and skin removal of débrided skin between passes, until
tightening immediately and over time.14 Clinically, the desired effect is achieved, usually evident
CO2 laser resurfacing is used to treat photodam- with color changes.13 The resurfacing may be per-
aged and aging skin and scars. It produces formed in a segmental fashion or over the entire
dramatic and significant changes for photodam- face. The results from full facial resurfacing have
aged, wrinkled, and scarred skin.15–17 generally been believed to be more beneficial,
The CO2 laser technology has evolved to an because lines of demarcation with respect to
ultrapulse method, which limits thermal damage erythema and texture may be observed with seg-
and leads to decreased scar formation. The mental resurfacing. This effect may be especially
prominent in dark-skinned patients.18 Should seg-
Actinic keratosis mental resurfacing be the best choice for a given
patient, however, feathering techniques may be
Wrinkles
applied, either with the laser or with dermabrasion,
to prevent demarcation.13,24 Because men do not
IR, RF devices generally use cosmetics to camouflage the skin,
PDT
full-face resurfacing is preferable to segmental fa-
cial resurfacing for the male demographic (Fig. 4).
Q-switch The risks and complications of CO2 laser resur-
PDL IPL Fraxel facing include edema, erythema, contact dermati-
tis, reactivation of herpetic lesions, infection,
KTP PSR hyperpigmentation, hypopigmentation, and scar-
ring.13,14,19,22 Edema and erythema generally
resolve within a few months. Erythema occurs in
nearly all patients.22 Prophylactic treatment and
early treatment once identified leads to prompt
Telangiectasis Hyperpigmentation
resolution of contact dermatitis, herpetic infec-
Fig. 3. Treatment applications for multiple nonabla- tions, and bacterial infections. Complications
tive facial resurfacing modalities. IPL, intense pulsed related to pigmentation are more frequent in
light; IR, mid-infrared lasers; KTP, potassium titanyl
patients who have darker skin. Hyperpigmenta-
phosphate vascular laser; PDL, pulsed dye lasers; PDT,
photodynamic therapy; PSR, portrait plasma skin
tion, which is usually temporary, is seen in up to
regeneration; RF, radiofrequency devices. (From 37% of patients; once recognized, it is effectively
Ruiz-Rodriguez R, Lopez-Rodriguez L. Non-ablative treated with topical bleaching creams and, if an
skin resurfacing: the role of PDT. J Drugs Dermatol inflammatory component is present, with steroids
2006;5:756–62; with permission.) also19,22 Hypopigmentation, observed in less
Facial Resurfacing of the Male Patient 361

Fig. 4. Algorithm for the treatment of rosacea and rhinophyma. (From Rohrich RJ, Griffin JR, Adams WP Jr.
Rhinophyma: review and update. Plast Reconstr Surg 2002;110:860–69 [quiz: 870]; with permission.)

than 1% of patients in a large retrospective study, 16 times greater than the CO2 laser.27 Because
is a delayed complication that becomes apparent of this, when compared with CO2 it is particularly
12 to 18 months after the procedure. It is generally effective in superficial tissue ablation while limiting
permanent and occurs more commonly in patients adjacent thermal injury. Given the ablative nature
who have dark skin.19,22 Unfortunately, there is no of CO2 and erbium:YAG resurfacing and potential
effective treatment of this hypopigmentation.19 of postoperative pigment changes, most authors
Scarring is a severe complication of CO2 laser re- recommend these modes of therapy for lighter-
surfacing. Patients who have risk factors, such as skinned individuals (Fitzpatrick I–IV) but agree
prior cosmetic procedures and isotretinoin use, that if darker-skinned individuals are to be treated
are predisposed to scarring. Ectropion has been erbium:YAG is a more appropriate choice than
reported also.22 These risks and complications CO2.28–30 There are short-pulsed and modulated
highlight the limitations of CO2 laser resurfacing. (short- and long-pulsed) erbium:YAG lasers. Treat-
Despite the risks, complications, and limitations, ments result in less erythema, decreased side
CO2 laser resurfacing remains an excellent treat- effects, and rapid healing when compared with
ment choice for photodamaged, aging, or scarred CO2 resurfacing, which can result in an extended
skin, provided that the patient is carefully selected period (months) of re-epithelialization with as
and has reasonable expectations, including many as 20% of patients developing delayed-
a thorough understanding of the treatment course onset permanent hypopigmentation.29
and recovery period. Given the decreased amount of thermal injury
seen with the erbium:YAG laser, for some patients
topical anesthesia might be adequate; however,
Erbium
most authors recommend local infiltration with
Along with CO2 laser, the erbium:YAG laser lidocaine with epinephrine for small cosmetic
system is one of the most frequently used lasers units, although for larger areas regional nerve
in skin resurfacing.26 Although CO2 and erbium: blocks with our without intravenous sedation
YAG lasers share the same chromophore, water, should be used.29 Postoperatively, the laser-
the absorption by water of the erbium laser is treated skin must be kept clean and moist using
362 Poore et al

Aquaphor or a petroleum dressing until re-epithe- each anatomic unit to avoid potential lines of
lialization occurs, which typically takes 5.5 days for demarcation.
erbium:YAG and 8.5 days for CO2.31 There is Although the skin re-epithelializes in 5 to 7 days,
a reduced incidence of hypopigmentation com- some erythema may persist for up to 4 weeks.
pared with CO2 laser and shorter recovery times. Adverse effects associated with dermabrasion
For superficial resurfacing 3 to 4 days are usually include postinflammatory hyper- and hypopig-
required, whereas with deeper resurfacing, 6 to mentation, persistent erythema, hypertrophic
10 days are usually required. In male patients, in scarring, herpes simplex virus, and bacterial skin
whom increased autonomy and less downtime infection. Postoperatively, most authors advocate
are particularly important factors when consider- keeping the wound moist using an antibiotic oint-
ing resurfacing, the erbium:YAG laser holds a dis- ment, Vaseline gauze, or another type of hydrocol-
tinct advantage over CO2 resurfacing. loid dressing. These should be changed daily for at
least 5 days.
One particular area in which dermabrasion is
Dermabrasion
effective is in the treatment of perioral rhytides.
Dermabrasion, a technique of skin resurfacing that Although dermabrasion was once one of the
involves mechanical removal of the epidermis and first-line treatments, and is a relatively inexpensive
parts of the dermis, has a longer history in facial mode of therapy, it is technically difficult to master
resurfacing than most other modalities. The first and in the hands of an inexperienced user the re-
use of controlled abrasion of the skin using rasps sults can be varied. Because lasers are easier to
and burrs with rotation to treat acne scars, kerato- technically master concerning depth of tissue
sis, and areas of hyperpigmentation was reported injury, modalities such as CO2 resurfacing have
by Kromeyer in 1905. More contemporary equip- largely supplanted dermabrasion. Dermabrasion
ment, such as a wire-brush dermabrasion and laser resurfacing have specific advantages
machine, were used in the 1950s.9 The equipment and disadvantages. There are several controlled
and techniques have been refined over the years. studies directly comparing the efficacy of derm-
Small, portable dermabraders are most popular abrasion and CO2 lasers for the treatment of perio-
today and use various end pieces, including wire ral rhytides. Holmkvist and Rogers32 compared
brushes, diamond fraises, and serrated wheels. dermabrasion to CO2 laser by treating one half of
These tools mechanically abrade the epidermis the perioral area with dermabrasion and the other
and dermis in succession, leading to the regener- half with superpulsed CO2 laser. They found no
ation of the epidermis. Postoperative wound care statistical differences between the two groups.
involves either an open or a closed dressing sys- In a similar study, Gin and colleagues33 compared
tem. Moist wounds allow for faster healing. Re-ep- the 950-millisecond dwell time CO2 laser to man-
ithelialization takes approximately 1 week, with up ual tumescent dermabrasion and found both
to 4 weeks of residual erythema. modalities equally effective. Kitzmiller and col-
The goal of dermabrasion is to rejuvenate the leagues 34–37 compared the effectiveness of derm-
skin by removing a controlled thickness of dam- abrasion and CO2 laser and found that there was
aged skin, thereby stimulating normal wound slightly better outcome in those treated with CO2
healing and skin rejuvenation. Dermabrasion me- laser. Despite the slight clinical difference patients
chanically removes the epidermis and parts of were evenly split in which technique they would
the dermis while leaving the deep epidermal recommend to a friend. The authors argue that
appendages located deep in the dermis. It is both techniques are essentially equally effective
from these appendages that the epidermis regen- in the treatment of perioral rhytides.
erates. Unlike laser resurfacing, dermabrasion
does not affect melanocytes, so disorders of pig-
Chemical Peels
mentation following treatment are less of a prob-
lem than in laser resurfacing. Clinical indications Chemical peels, also known as chemexfoliation or
for dermabrasion include: surgical and traumatic dermapeeling, have been used for more than 100
scarring, acne pits and scars, rhinophyma, and years. They are used to target the signs of photo-
facial rhytides. Typically, this is performed using aging and acne scars and precancerous lesions.
local blocks in combination with refrigerant topical They are made up of superficial, medium-depth,
anesthesia, which helps freeze and stiffen the skin and deep chemical peels. Medium-depth and
before dermabrading. Several authors advocate deep chemical peels are the types used to target
dermabrading the forehead first followed by the the photdamaged skin and rhytides.38 The best
cheeks, chin, upper lip, and then the nose, while results are observed with deep chemical peels,
being particularly careful to feather the edges of which also have the longest recovery time and
Facial Resurfacing of the Male Patient 363

a higher risk for adverse effects, including cardiac NONABLATIVE RESURFACING


and renal complications. Skin Care and Retinoids
Medium-depth peels use trichloroacetic acid
Retinoids, which include retinol, retinal, retinyl
35% to 50% alone or 35% combined with Jess-
palmitate, retinyl acetate, and retinoic acid, all
ner solution (resorcinol, salicylic acid, ethanol,
derivatives of Vitamin A, can be the most effective
and lactic acid), glycolic acid 70%, or solid car-
component to reverse photoaging. In fact, given
bon dioxide. Medium-depth peels combined
their effectiveness and simplicity of use, the lowest
with other agents use a lower concentration of
rungs of the facial plastic surgeon’s skin resurfac-
trichloroacetic acid and avoid complications
ing treatment ladder must be occupied by the use
associated with the higher concentrations, such
of retinoids. Of all the retinoids, trans-retinoic acid
as scarring. This technique penetrates to the
(tretinoin) is the most bioactive form. When applied
papillary dermis and upper reticular dermis. After
to the skin it primarily causes thinning of the stra-
approximately 1 week there is coagulative necro-
tum corneum, leading to a smoother skin texture.
sis of the epidermis and collagen necrosis of the
It has also been shown to disperse melanin gran-
papillary and upper reticular dermis, which leads
ules leading to the reduction of hyperpigmentation
to edema of the dermis and homogenization of
in treated areas. It also treats fine lines and rhyti-
the mid-reticular dermis.38
des by increasing glycosaminoglycan deposition
The complications associated with medium-
in the dermis and increases collagen production.
depth chemical peels include hypopigmentation,
The use of tretinoin is not without side effects
hyperpigmentation, erythema, hypertrophic and
and retinoid dermatitis, characterized by dry skin,
keloid scars, and infections. These reflect the
burning sensations, peeling, and itching, is
normal wound healing process. Hyperpigmenta-
a well-documented sequela of tretinoin use. Also,
tion is usually temporary and resolves with
because tretinoin thins the stratum corneum, its
wound care. Hypopigmentation, observed more
use makes the skin much more sensitive to
frequently with deep chemical peels, does not
sunlight and sun block should be used at all times.
have a good solution, aside from cosmetics,
Tretinoin is available in multiple formulations and
which would not be well-received among the
concentrations, including a cream, solution,
male demographic. Erythema is observed 1 to
microspheres, and an emollient (eg, Renova).
2 weeks after treatment and may persist for up
Tretinoin is most commonly applied at night be-
to several months. Scars are observed with high-
cause it is degraded by sunlight and patients are
er concentration in medium-depth peels and
usually started on a low concentration (0.025%)
deep chemical peels. Infections result from
on an every-other-day schedule. Once tolerated,
poor wound care and are easily treatable with
daily application a higher doses can be used.
topical antibiotics.
Tretinoin should not be used in isolation but should
Deep chemical peels use phenol 50% to 88% in
rather be incorporated into a consistent and com-
combination with distilled water, hexachlorophene
prehensive skin care regimen, such as the one
soap, and croton oil, known as Baker and Gor-
described by Boswell.5
don’s formula. Diluting the phenol and combining
it with water allows for deeper skin penetration.
The soap reduces surface tension and the croton
Fractional Skin Resurfacing
oil acts a vesicant, allowing the phenol to reach
a deeper layer of the skin. This peel reaches the Fractional resurfacing, fractional technology, or
mid-reticular dermis, leading to epidermal necro- fractional thermolysis involves skin rejuvenation
sis and dermal edema and homogenization of in a specific thermal damage pattern. It produces
the dermis. This mechanism is the same as seen microthermal treatment zones, which are discrete
in medium-depth peels.38 Given the deep penetra- columns of thermal damage at specific depths in
tion of the agents, however, there is a higher a repeated skip pattern.10,12 The surrounding tis-
potential for adverse events and toxicity. These sue is spared, which leads to rapid epidermal
adverse events include cardiac arrhythmias, regeneration and repair. Because the process of
hypertrophic scars, prolonged erythema, pigment collagen remodeling and new collagen formation
changes, atrophy, laryngeal edema, and toxic occurs in the dermis and affects the epidermis
shock syndrome. These can be avoided with care- also, fractional resurfacing is ideal for the improve-
ful application and methodology with deep chem- ment of rhytides and scars.12 The result is
ical peels. Hypertrophic scars result from smoother skin with improved tone and texture.10
penetration of the deeper layers of the dermis. Fractional resurfacing may be ablative or nonabla-
They can be treated with steroids if recognized tive, targeting deep or superficial wrinkles,
early.38,39 respectively.
364 Poore et al

Fractional resurfacing has been shown clinically delayed healing and scarring and delayed
and histologically to require less time for healing hypopigmentation.10,41
than ablative technologies, such as CO2 lasers.12
Nonablative fractional resurfacing has predictable
Plasma Skin Resurfacing
side effects, including edema and erythema, that
last up to 1 week, which is far less than the PSR uses radiofrequency energy to convert nitro-
reported downtime with CO2 lasers.40 Generally, gen gas into plasma, which leads to rapid and pre-
three to five treatments are administered 1 to cise heating of the skin tissue with minimal thermal
4 weeks apart. Because darker-skinned patients injury to the surrounding tissues.42 Unlike carbon
are at a higher risk for postinflammatory hyperpig- dioxide lasers, PSR is not chromophore depen-
mentation, longer intervals between treatments dent, allowing for even delivery of energy to the
are recommended.12 skin.42 PSR leads to zones of effect. The zone of
Because fractional thermolysis is relatively new, thermal damage is characterized by nonviable
the most commonly studied system is the first one cells as a consequence of vaporization of the
introduced, the Fraxel SR laser (Reliant Technolo- tissue. A new epidermal layer forms 2 to 3 days
gies).12 It is an erbium-based system and is gener- after treatment. The zone of thermal modification
ally used in a nonablative manner. This technique contains viable, although modified, tissue. Fibro-
usually requires local anesthesia applied approxi- blast activity in this zone leads to new collagen
mately 1 hour before the procedure, because and elastin formation.42 The stratum corneum
discomfort during the procedure is common. and the epidermis are left intact.
A cooling device is generally applied. Benzodiaze- PSR is performed at an energy setting adjusted
pines and narcotics may be used to relieve anxiety for the target tissue, ranging from 1 to 4 J with non-
and pain in sensitive patients.6 The number of overlapping pulses, with the effects dependent on
passes is tailored to the treatment level for each the energy level. Fitzpatrick and colleagues (2005)
patient. The treatment energies range from 6 mJ found that collagen remodeling depended on the
to 12 mJ for superficial lesions including melasma energy setting used in a study examining the
and dyschromasia. Higher energy levels from effects of PSR on rhytides.
10 mJ to 20 mJ target wrinkles. Deep wrinkles Histologic evaluation of the effect of PSR on
and scar may require 25 mJ to 40 mJ, used with collagen regeneration was performed as part of
great care. Each treatment usually involves 8 to a clinical study by Kilmer and colleagues.42 Skin
10 passes.6,41 samples, taken pretreatment and 90 days after
Postoperative care is similar to other laser pro- treatment, were sent for histologic evaluation
cedures and includes careful hygiene and the examining markers of collagen formation and elas-
use of sun protection. Patients may return to tic properties of skin. The investigation showed
work the day after surgery. They can expect complete, intact epidermis in all specimens. The
some erythema and edema, which usually resolve dermis showed normal architecture and de-
in less than 1 week, so downtime is minimal. The creased solar elastosis. Scarring and incomplete
main risks include laser nicks, blistering and crust- healing with disorganized dermal architecture
ing, reactivation of herpes infection, postinflam- were not observed. Neocollagenesis was ob-
matory hyperpigmentation, and hypertrophic served with variability.42 Other studies have
scarring.12,39 Postinflammatory hyperpigmenta- included histologic evaluation and have shown
tion is more common in darker-skinned patients collagen remodeling with less variability.43 Scar-
and may be transient.6 ring and dyspigmentation resulting from PSR
Fractional thermolysis has been shown to treat were not observed at the histologic level.42
melasma with good efficacy and a low incidence Clinical studies on PSR have not shown scarring
of side effects, such as postinflammatory hyper- or dyspigmentation after the procedures. Mild
pigmentation and hypopigmentation.39 Compari- erythema and desquamation were noted at low
son with the gold standard of CO2 lasers is settings and increased at higher settings. Hyper-
limited to comparisons rather than head-to-head pigmentation resulting from PSR was not ob-
studies. The available data demonstrate that frac- served. Patients who had hyperpigmentation
tional thermolysis works well for some lesions with before treatment had improvement in hyperpig-
decreased side effects, but does not provide the mentation after treatment with single-pass, high-
dramatic, reliable results seen with CO2 energy (3–4 J) PSR.42 The lack of posttreatment
lasers.10,41 CO2 lasers have approximately 4 hyperpigmentation and scarring makes PSR ideal
weeks of downtime, as compared with 1 week for patients who are more likely to develop these
for fractional thermolysis.10 CO2 lasers carry sequelae, such as dark-skinned patients.22 Dys-
a higher risk than fractional thermolysis, including chromias and scarring are the primary reasons
Facial Resurfacing of the Male Patient 365

for which treatment is sought in dark-skinned been performed examining the clinical and histo-
patients. (Jackson 2003/Jackson 2003) It is the logic effects of Coblation. Histologic evaluation
melanin content of dark skin that makes it resistant of 15 subjects in one study revealed new upper
to many of the signs of photoaging and makes it papillary dermis collagen formation after cobla-
more susceptible to dyschromia secondary to tion.46 The clinical results in the study, decreased
trauma and inflammation. (Jackson 2003/grimes perioral and periorbital rhytides with complete re-
2000) Although most studies examining PSR and epithelialization within 7 days, reinforced the histo-
other skin resurfacing modalities have few partici- logic finding.46 Scarring has also been shown to be
pants who are Fitzpatrick skin types IV through VI, safely treated with the Visage system.47
the lack of side effects, which are more prevalent A prospective, multicenter study demonstrated
in this demographic, make PSR a natural and ideal efficacy of Coblation for periorbital and perioral
choice for dark-skinned patients. rhytides in patients who have Fitzpatrick type I to
Generally, this type of nonsurgical cosmetic III skin.48 This study, as with most studies of
enhancement is well tolerated by patients and Coblation, focused on patients who had Fitzpa-
results in improved skin texture, tone, fine lines, trick type I to III skin, because hyperpigmentation
dyschromia, and rhytides with minimal side is a known side effect of many ablative skin resur-
effects.42 These characteristics make PSR a likely facing modalities. The number of passes and volt-
choice for men who desire subtle enhancement of age correlated positively with improvement in
their appearance with minimal side effects. The rhytides in 95 patients. Transient hypopigmenta-
effects of PSR on the skin of the neck have been tion and scarring have been observed, but are
examined and shown to reduce the signs of photo- rarely permanent, usually resolving within
damage with the similar low side-effect profile 6 months.47,48
seen in the use of PSR on facial skin. Although fur- Overall, bipolar radiofrequency has been shown
ther studies are needed to elucidate the most to be efficacious for rhytides with several weeks of
effective treatment protocol, the use of PSR on posttreatment erythema and edema. Although this
the skin of the neck is promising.44 is less than other ablative methods of skin resur-
facing, it is longer than with some of the newer
nonablative methods of skin resurfacing.
Coblation
As such, bipolar radiofrequency has been com-
Coblation, or cool ablation, is a bipolar radiofre- bined with nonablative optical technologies to
quency technology that uses two electrodes set achieve the benefits of each type of technology
close to each other, with a gap filled by tissue while maximizing the limited side effects. The
and fluid, usually saline. When voltage is applied Aurora applicator combines the radiofrequency
to the electrodes, tissue is vaporized that ulti- and intense pulsed light. ReFirme ST combines
mately leads to tissue exfoliation with subsequent radiofrequency and infrared light. Polaris WR com-
re-epithelialization. This technology prevents col- bines radiofrequency and diode laser. The Aurora
lateral damage to surrounding tissues, because SR is recommended for treatment of telangiecta-
the ions lose energy quickly. Each pass achieves sias, rosacea, and other lesions with symptom-
more ablation, beginning with the dermis and atology in the epidermis and superficial dermis.
extending to the epidermis with subsequent Polaris WR and ReFirme ST target rhytides and
passes. Although re-epithelialization is achieved skin laxity. A study of 100 patients using the Aurora
in approximately 1 week, leading to less downtime SR used three to five treatments of one to three
than traditional carbon dioxide laser resurfacing, passes with optical fluencies ranging from 28 to
the dermal damage leads to a mild erythema that 34 J/cm2 and a radiofrequency of 20 J/cm2 to
lasts for several weeks.45 For the male demo- examine its efficacy on dyschromias and rhytides.
graphic, this would likely be preferable to ablative The Aurora SR reduced dyschromias, telangiecta-
carbon dioxide and erbium:YAG laser resurfacing sias, and rhytides with minimal side effects.49,50
with improvement in fine and deep wrinkles and
lentiginies.29 As with other forms of ablative tech-
Acne
nology, the potential for deep thermal penetration
and the damage to melanocytes is high and the Puberty, and the concomitant increase in the con-
resultant hypopigmentation can be significant. centration of circulating androgens, is the herald-
Coblation is not recommended for individuals ing event in the development of acne vulgaris
who have Fitzpatrick skin types IV and higher. and therefore its development is universally
The most commonly studied electrosurgical unavoidable. In fact 95% to 100% of 16- to
system is the Visage Cosmetic Surgery System 17-year-old boys and 83% to 85% of 16- to 17-
(ArthroCare Corporation). Several studies have year-old girls develop acne vulgaris.51 Although
366 Poore et al

the condition usually remits spontaneously by age used a 1550-nm erbium-doped fiber laser (Fraxel,
25, approximately 95% of individuals display Reliant) applied to the scarred regions in 8 to
some degree of post-acne scarring. The develop- 10 passes after the application of 30% lidocaine
ment of post-acne scarring is a complex interplay solution for 60 minutes. This treatment was per-
of the inhibited outflow of sebum from sebaceous formed on all patients at monthly intervals for
glands to the skin surface followed by the develop- 3 months with the ultimate conclusion that when
ment of either open or closed comedones and the compared with CO2 resurfacing there were similar
possible differentiation into an inflamed acne clinical improvements with less downtime and
lesion caused primarily by the obligate anaerobe fewer side effects.
Propionibacterium acnes in the context of the Microdermabrasion was originally used as
anaerobic conditions of a closed comedo.52,53 a treatment of acne and scarring and remains pop-
Although techniques in facial resurfacing have ular despite the arrival of newer treatments.
proved beneficial in the treatment of post-acne Limited evidence investigating the use of micro-
scarring, including chemical peels, microdermab- dermabrasion for acne demonstrates good effi-
rasion, dermabrasion, plasma, and multiple laser cacy.60 It is well-tolerated by patients, with few
and light treatments, there is now an increasing side effects. Erythema is the main side effect,
body of literature on the treatment of active acne which resolves within 24 hours. Investigation of
vulgaris with various light and laser therapies, the clinical histologic effects of microdermabra-
including blue/blue red light combinations, sion demonstrates moderate improvement with
1450-nm diode laser, and intense pulsed light acne scarring, usually requiring deeper treatment.
(IPL) with or without aminolevulinic acid (Levulan) The usefulness of microdermabrasion for acne is
enhancement. Although a full description of these as an adjunct to other procedures, such as photo-
therapies is beyond the scope of this article, one dynamic therapy.56 Removal of acne scars
emerging and promising technology worthy of dis- requires penetration to the superficial papillary
cussion is Levulan-enhanced IPL. In a split-face dermis. Of note, microdermabrasion may exacer-
study, Alster and colleagues53 evaluated the effec- bate telangiectasia and erythema so patients
tiveness of Levulan-enhanced IPL therapy com- who have acne rosacea should not be offered
pared with IPL alone. They demonstrated higher microdermabrasion.61 Superficial chemical peels,
clinical improvement scores on the side of the including alpha-hydroxy acids, such as glycolic
face treated with a combination of Levulan and acid, and salicylic acid, have shown efficacy pri-
IPL compared with IPL alone. A similar split-face marily in the treatment of acne. The glycolic peels
study was conducted by Santos and colleagues,54 led to improvement in active acne and in the post-
who demonstrated similar conclusions. For a thor- inflammatory changes observed with acne
ough review of the other techniques the reader is scarring. Salicylic acid peels have shown improve-
referred to reviews by Ortiz and colleagues, ment in acne in several studies. There were few
Taub, and Goodman and Baron.55–57 side effects, including erythema, dryness, and
Acne scars occur as a function of the extent of crusting. Superficial chemical peels work well as
inflammation, abscess formation, and fistulous an adjunct to systemic and topical therapies for
tract development. Overall, acne scars are most the inflammatory stages of acne.56
often atrophic resulting from inflammation deep
in the tissues and subsequent scarring with ulti-
mate contracture resulting in indentation and atro- Rhinophyma
phy. In certain individuals acne scars become ‘‘I take inordinate pride in my nose. Indeed,
thickened, resulting in hypertrophic or keloid scar- I have treatment done on it every day.’’ (At
ring. This scarring usually occurs in those who this point, Fields is handed a glass and lifts
have a family history of hypertrophic or keloid it.) ‘‘My daily treatment.’’
scarring. —From W.C. Fields: A Life on Film
Ablative and nonablative technologies have
been used for the treatment of atrophic scars. Contrary to popular belief, rhinophyma, charac-
Although ablative technologies, including CO2 terized by an erythematous, discolored, hypertro-
and erbium lasers, have proved effective in the phied, and inflamed nose, is not the result of
treatment of atrophic scars, the collateral thermal chronic alcoholism; it is the fourth and most severe
damage can lead to significant downtime and stage of rosacea. The first three stages are classi-
potential side effects.28,58,59 Recently, Alster and fied as prerosacea (frequent facial flushing), vas-
colleagues59 reported success with fractional pho- cular rosacea (thickened skin, telangiectasis,
tothermolysis in a group of 53 patients who had facial erythema, and erythrosis), and inflammatory
mild to moderate atrophic facial acne scars. They rosacea (erythematous pustules and papules of
Facial Resurfacing of the Male Patient 367

the face, forehead and nose). Although rosacea is Rohrich and colleagues25 use a combination of
more common in women, the progression to full- cold excision with a scalpel followed by dermabra-
blown rhinophyma is more common in men, which sion for fine sculpting. They also use electrocau-
may be attributable to androgenic influence. An in- tery for hemostasis and either erbium or CO2
fectious cause has also been postulated because laser for hemostasis only when electrocautery is
plugged sebaceous glands are typically colonized not sufficient. Postoperatively they use a combina-
with bacteria. It remains unclear, however, if bac- tion of Xeroform gauze antibiotics for 4 days twice
terial colonization is a primary or secondary com- daily starting on postoperative day one. They do
ponent of the disease process. Rhinophyma is not use ointment for more than 3 days to prevent
classified on severity of the deformity and maceration but do continue with Xeroform gauze
includes: until re-epithelialization occurs and the nose is
healed (usually 4 weeks).
Early vascular type Fincher and Gladstone64 described the tech-
Diffuse enlargement (moderate) nique of dual-mode erbium:YAG laser for correc-
Localized tumor (early) tion of rhinophyma in six patients with excellent
Diffuse enlargement (extensive) results. The authors use a dual-mode erbium:YAG
Diffuse enlargement (extensive and localized laser with a scanning laser hand piece set of 3 mm
tumor) spot, 100 mm of ablation, and 50 of coagulation.
A full exploration in the treatment of rosacea They perform an average of four passes. Postop-
and rhinophyma is beyond the scope of this article eratively they use an occlusive dressing for
and for a full analysis the reader is referred to Roh- 3 days and the Aquaphor for 2 weeks. They con-
rich and colleagues.25 Various skin resurfacing clude that using this technique provides excellent
modalities play a significant role in treatment. hemostasis and less nonspecific thermal damage,
For simple rosacea, topical and oral antibiotics and anecdotally report more rapid re-epitheliza-
are the mainstay of treatment. For more advanced tion than with CO2 laser even though there are
forms surgical therapy includes dermabrasion, no specific studies comparing the two
cryosurgery, loop cautery, and CO2 lasers. An modalities.64
algorithm from Rohrich and colleagues25 is pre-
sented in Fig. 4.
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