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B-UNAWARE Trial
B-UNAWARE Trial
Aviden et al
NEJM 2008
Population
2000 patients
Very broad criteria for patients – NOT STRICTLY high risk groups as compared to B-
AWARE
Intervention
Standard monitoring – BP, HR, ET gas analysis + MAC
Above + BIS
Outcome
Episodes of awareness
Message
Issues
- Hawthorne effect as in B-AWARE
- Not multicentre
- Much looser criteria for enrollment