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B-UNAWARE Trial

Aviden et al
NEJM 2008

RCT – NOT MULTICENTRE

Population
2000 patients
Very broad criteria for patients – NOT STRICTLY high risk groups as compared to B-
AWARE

Intervention
Standard monitoring – BP, HR, ET gas analysis + MAC
Above + BIS

Outcome
Episodes of awareness

Message

Showed NO difference between the two groups with respect to awareness

Issues
- Hawthorne effect as in B-AWARE
- Not multicentre
- Much looser criteria for enrollment

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