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The Use and Abuse of Drugs Notes - Biology - 5090 Notes - O Level Academy
The Use and Abuse of Drugs Notes - Biology - 5090 Notes - O Level Academy
Medicinal drugs, like antibiotics, are taken in to correct the body’s metabolism. Antibiotics only cure
bacterial infections, as they are made from fungi that produce chemicals that kill the bacteria. When they
are taken in, they puncture the cell wall of the bacteria causing them to burst. At times, they even stop the
enzyme production or protein synthesis of the bacteria.
Some bacteria are resistant to antibiotics which reduces the effectiveness of the antibiotic. Those bacteria
have an extra coat, known as the resistant coat. If the medicine is stopped before the resistant bacteria are
dead, the bacteria will reproduce. MRSA is an extremely dangerous bacteria as it is resistant to most
antibiotics. To slow down and stop the development of other strains of resistant bacteria, we should:
Antibiotics only kill bacteria, and they do not affect other cells, like viruses. This is because antibiotics kill the
bacteria by damaging their cell walls. Viruses don’t have cell walls, so they remain unharmed by antibiotics.
Viruses are not living cells; They are simple protein structures with no metabolism so antibiotics have no
effect on them. The chemical properties of antibiotics are specific to the bacterial cell whereas viruses are
much smaller in different shapes.
Heroin
Heroin is a powerful depressant drug obtained from opium. It increases reaction time e.g. thinking and
blinking. When a person stops the intake of heroin, they suffer from severe physiological and physical
symptoms like severe body pain, nausea, headache etc. It reduces pain and slows down breathing.
Effects
● Increases reaction time.
● Causes inflammation of the gums
● Weakens the immune system
● Can lead to depression
● Can cause insomnia
Abuse
● Heroin abuse may increase criminal activity as addicts turn to crime, like robbery, to finance their
addiction, so more opportunity to become drug dealers.
● Injecting heroin can cause infections, such as HIV since a lot of these needles are not sterile and are
shared amongst many people. This causes widespread disease.
Withdrawal Symptoms
● Sleeplessness
● Hallucinations
● Muscle cramps
● Nausea
● Vomiting
● Headaches
● Sweating
● Aggression
● Diarrhea
● It affects the medulla of the brain which is the life-support center of the body. It can cause a halt in
breathing, causing brain damage and death. Its consumption in excess decreases a person’s self-control,
nervous control, and muscular control. It also affects the brain by reducing the levels of ‘calming agents’ in
the brain, therefore disturbing the sleep pattern.
● Alcohol is addictive, so when you once start taking it, your body starts being dependent on it. The natural
chemicals get replaced by the drugs. If you don’t take the same amount from time to time, you will suffer
from severe body pain, nausea, vomiting, blurred vision, headaches etc. It will lead to the body being unfit. It
can even lead to financial problems, and higher chances of the addict committing crimes.
● Excessive alcohol consumption leads to liver cirrhosis. The main function of the liver is to detoxify drugs, so
when it becomes overloaded with alcohol, it will definitely get damaged. The normal liver cells which line
blood vessels change to fibrous mass of cells, causing the malfunctioning of the liver.
Carbon monoxide
● Due to the burning of tobacco, carbon monoxide is obtained. This is a highly toxic gas. When it enters the
body, it combines with hemoglobin as the hemoglobin has more affinity for carbon monoxide than oxygen.
As a result of this, carboxyhemoglobin is formed. This will cause a decrease in oxygen levels of our bodies.
The carboxyhemoglobin will lead to anaerobic respiration as it does not allow oxygen to reach our body
cells. Therefore, more levels of lactic acid will be formed in the body causing the cells to become fatigued,
leading to myocardial infarction.
Nicotine
● It is a stimulant and an addictive drug. It mimics the natural neurotransmitters in the brain which are
concerned with heartbeat and blood pressure. Nicotine causes an increase in the heartbeat rate, narrowing
the blood vessels which causes an increase in blood pressure. Due to the increased heartbeat, there is a
higher demand for oxygen, but the presence of carbon monoxide reduces its availability, causing damage
to the heart muscles.
● Due to nicotine, the body fats are accumulated and deposited in the coronary arteries. This makes the
lumen shorter, and oxygen will not be able to reach the heart, causing the heart muscles to be fatigued.
Another effect of the fat deposition is that the coronary artery wall will break, becoming uneven. This causes
blood clots to accumulate which results in cardiac arrest.
Tar/Carcinogens
● Tar is the black, sticky substance present in tobacco smoke. It is a carcinogen which mutates the cells of
the respiratory tract, causing cancer. The most common ones are lung cancer, mouth cancer, and throat
cancer.
● As it enters the trachea, it sticks the cilia together. This blocks the air passages and prevents mucus,
secreted from the goblet cells, to enter the esophagus. Thus, the mucus will stay in the respiratory tract. This
will increase the chances of bacterial infection as the bacteria are trapped in the mucus. Due to throat
inflammation, the gaseous exchange passage will be narrow, and the person will face difficulties while
breathing. This leads to spontaneous coughing and inflammation of the trachea. A lot of carbon dioxide will
accumulate in the cells, blocking the small bronchioles with mucus. The alveoli will eventually burst, and the
surface area for gas exchange decreases. This is known as Chronic Obstructive Pulmonary Disease (COPD).
It includes chronic bronchitis and emphysema. Chronic bronchitis refers to spontaneous coughing, while
emphysema refers to the bursting of alveoli.
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