Nucleic Acids 85

A. DNA: structure
5' 3'

H
H
N H

3.4 nm
C C O O P O
H
O C N
C C O
N H C C H
N C N G CH2 C G
C N O
O C N
O H A T
H2 C N

O H
H O

0.34 nm
O P O O CH3 O
H N N H P O
O C C C
C C O
N C A N H N T C H
CH 2
N C C N O
O H O
H2 C
Minor Major
O OH CH2OH groove groove
O O
O P O
2'-deoxy- H H
D-ribose 5' 3'
H 2 H
H OH
1. Formula 2. Double strand

B. Coding of genetic information

3' 5' 3' 3' C

C
Codon
(triplet) T Phe
T
Sense strand C
(+) strand, A Tyr
“coding strand” T
T
C Ala
G
T
C Thr
A
A
Template A Glu
strand G
(–) strand, A
“codogenic A Glu
strand”
G
G
T Met
A
5' N
1. 2. 3.

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme

All rights reserved. Usage subject to terms and conditions of license.