RYREY A.

PACAMANA BSN 3C DRUG STUDY

DRUG CLASSIFICATI DOSE, MECHANISM OF INDICATION CONTRAINDI SIDE EFFECTS/ NURSING

ON FREQUENC ACTION CATION ADVERSE EFFECTS RESPONSIBILITIES
Y, ROUTE
Acetaminoph Antipyretics, 250 mg Antipyretics: Common cold, Contraindicated CNS: Headache Advise relatives or
en analgesics (non- PRN Reduces fever by flu, other viral with allergy to caregivers to check
opioid) Per Orem acting directly on the and bacterial acetaminophen CV: Chest pain, concentrations of liquid
hypothalamic heat- infections with dyspnea, myocardial preparations. Errors have
regulating center to pain and fever damage when doses of resulted in serious liver
cause vasodilation 5-8g/day are ingested damage.
and sweating, which daily for several weeks
helps dissipate heat. or when doses of Assess fever, note
4g/day are ingested for presence of associated
Analgesics: 1 year. signs (diaphoresis,
Site and mechanism tachycardia, and
of action unclear Hematologic: malaise).
hematuria, anuria,
neutropenia, Take the drug only for
leukopenia, complaints indicated: it
thrombocytopenia is not an anti-
inflammatory agent
Metabolic:
Hypoglycemia

GI: Hepatic failure,

hepatotoxicity
(overdose), jaundice
 RYREY A. PACAMANA BSN 3C DRUG STUDY

DRUG CLASSIFICATI DOSE, MECHANISM OF INDICATION CONTRAINDI SIDE EFFECTS/ NURSING

ON FREQUENC ACTION CATION ADVERSE EFFECTS RESPONSIBILITIES
Y, ROUTE
Fondaparinu Anticoagulants, 2.5 cc A synthetic activated Prevention of Hypersensitivity Fever, headache, Know the 10 Rights in
x (Arixtra) antiplatelet and OD factor X inhibitor thromboembol . Patient with insomnia, confusion, drug administration
fibrinolytic SQ that binds to ic phenomena active major pain, dizziness
antithrombin including DVT bleeding. Severe Monitor any signs of
and pulmonary renal bleeding and
embolism impairment hemorrhage. Withhold
medication and notify
physician if noted

Administer by SC
injection only. Don’t mix
with other injections or
infusions.

To avoid loss of drug, do

not expel air bubbles
from the syringe
 RYREY A. PACAMANA BSN 3C DRUG STUDY

DRUG CLASSIFICATI DOSE, MECHANISM OF INDICATION CONTRAINDI SIDE EFFECTS/ NURSING

ON FREQUENC ACTION CATION ADVERSE EFFECTS RESPONSIBILITIES
Y, ROUTE
Docusate Laxative 200 mg Promotes Used to Hypersensitivity EENT: throat irritation Assess: cause of
sodium BID incorporation of prevent , abdominal constipation - is fluid,
PO water into stools, constipation or pain, nausea, GI: mild cramps and fibre or exercise missing
promotes to soften fecal vomiting (with diarrhea from lifestyle; fluid
electrolyte/water impaction fever or other balance
secretion in colon signs of acute DERM: Skin
abdomen) Drug should be
discontinued if cramping,
rectal bleeding, nausea or
vomiting occur. 

Inform that normal

bowel movements do not
always occur daily.

Notify clinician if
constipation is
unrelieved or symptoms
of electrolyte imbalance
occur (muscle cramps,
pain, weakness,
dizziness).
 RYREY A. PACAMANA BSN 3C DRUG STUDY

DRUG CLASSIFICATI DOSE, MECHANISM OF INDICATION CONTRAINDI SIDE EFFECTS/ NURSING

ON FREQUENC ACTION CATION ADVERSE EFFECTS RESPONSIBILITIES
Y, ROUTE
Linezolid Anti-ineffective, 600 mg a synthetic antibiotic It is indicated Hypersensitivity Body as a Monitor for S&S of:
oxazolidinone BID belonging to a new for gram- to linezolid, Whole: Fever.  Bleeding; hypertension;
PO class of positive infecti pregnancy or pseudomembranous
antimicrobials called ons and (category C), GI: Diarrhea, nausea, colitis that begins with
the oxazolidinones. approved for lactation, vomiting, constipation, diarrhea.
Linezolid disrupts the treatment neonates. Safety taste alteration,
bacterial growth by of and abnormal LFTs, tongue Report any of the
inhibiting the bacterial pneu effectiveness in discoloration.  following to physician
initiation process in monia, skin children <2 y promptly: Onset of
protein synthesis. and skin not established. Hematologic: Thrombo diarrhea; easy bruising or
This site of inhibition structure cytopenia, leukopenia.  bleeding of any type; or
occurs earlier in the infections, and S&S of superinfection
initiation process vancomycin- CNS: Headache,
than other protein resistant insomnia, dizziness.  Avoid foods and
synthesis inhibitors  enterococcal beverages high in
(VRE) infectio Skin: Rash.  tyramine (e.g., aged,
ns, fermented, pickled, or
including infec Urogenital: Vaginal smoked foods, and
tions complica moniliasis. beverages).
ted by
bacteremia.
 RYREY A. PACAMANA BSN 3C DRUG STUDY

DRUG CLASSIFICATI DOSE, MECHANISM OF INDICATION CONTRAINDI SIDE EFFECTS/ NURSING

ON FREQUENC ACTION CATION ADVERSE EFFECTS RESPONSIBILITIES
Y, ROUTE
Ketorolac anti-pyretic, 30 mg Anti-inflammatory Short term Contraindicated Headache, dizziness, Be aware that patient
NSAID Q6 and analgesic management with significant somnolence, insomnia, may be at risk for CV
IV activity, inhibits of pain (up to renal fatigue, tinnitus, events, GI bleeding,
prostaglandins and 5 days) impairment, ophthalmologic effects renal toxicity, monitor
leukotriene synthesis aspirin allergy, accordingly
recent GI bleed
or perforation. Keep emergency
equipment readily
available at time of
initial dose, in case of
severe hypersensitivity
reaction

Protect drug vials from

light
 RYREY A. PACAMANA BSN 3C DRUG STUDY

DRUG CLASSIFICATI DOSE, MECHANISM OF INDICATION CONTRAINDI SIDE EFFECTS/ NURSING

ON FREQUENC ACTION CATION ADVERSE EFFECTS RESPONSIBILITIES
Y, ROUTE
Omeprazole Proton pump 40g Gastric acid pump Short-term Contraindicated CNS: Headache, Advise patient to
inhibitor OD inhibitor: suppresses treatment of with dizziness, asthenia, swallow capsules whole-
IVTT gastric acid secretion active hypersensitivity vertigo, insomnia, not to open, chew or
by specific inhibition duodenal to omeprazole apathy, anxiety, crush them.
of the hydrogen ulcer; first line or its paresthesia, dream
potassium ATPase therapy in components abnormalities Arrange for further
enzyme system at the treatment of evaluation of patient
secretory surface of heartburn or DERM: Rash, after 8 weeks of therapy
the gastric parietal symptoms of inflammation, for gastro reflux
cells; blocks the final gastroesophag urticarial, pruritus, disorders; not intended
step of acid eal reflux alopecia, dry skin for maintenance therapy
production disease
(GERD). GI: Diarrhea, Advise patient to take the
Short-term abdominal pain, nausea, drug before meals
treatment of vomiting, constipation,
active benign dry mouth, tongue Report severe headaches,
gastric ulcer atrophy worsening of symptoms,
fever, chills
RESPIRATORY: URI
symptoms, cough,
epistaxis

Other: Cancer in
preclinical studies, back
pain, fever
 RYREY A. PACAMANA BSN 3C DRUG STUDY

DRUG CLASSIFICATI DOSE, MECHANISM INDICATION CONTRAINDIC SIDE EFFECTS/ ADVERSE NURSING
ON FREQUENC OF ACTION ATION EFFECTS RESPONSIBILITIE
Y, ROUTE S
Hydrocodone  Opioid Hydrocodone is a indicated for  should not be CNS: Drowsiness, mental Monitor for
bitartrate analgesic full opioid agonist the administered to clouding, lethargy, effectiveness of drug
that interacts with management patients who have impairment of mental and for pain relief.
the mu-receptors of pain severe previously physical performance,
and, to a lesser enough to exhibited anxiety, fear, dysphoria, Monitor for nausea
extent, with delta require hypersensitivity psychological dependence, and vomiting,
receptors in the an opioid anal to hydrocodone or mood changes. especially in
body. Activated gesic and for acetaminophen. ambulatory patients.
mu-opioid which Patients known to GS: Constipation.
receptors lead to alternative be hypersensitive Monitor respiratory
inhibition of treatments are to other opioids Genitourinary status and bowel
nociceptive pain inadequate. may exhibit cross- System: Ureteral spasm, elimination.
reflexes and sensitivity to spasm of vesical sphincters,
induce profound hydrocodone. and urinary retention. Avoid hazardous
analgesia without activities until
affecting other Special Senses: Cases of response to drug is
sensory hearing impairment or determined.
modalities such as permanent loss have been
touch.  reported predominately in Drink plenty of
patients with chronic liquids for adequate
overdose. hydration.
Dermatological: Skin rash,
Do not take larger
pruritus, Stevens-Johnson
doses than prescribed
syndrome, toxic epidermal
since abuse potential
necrolysis, allergic reactions.
is high
Hematological: Thrombocyto
penia, agranulocytosis.

DRUG CLASSIFICATION DOSE, MECHANISM INDICATION CONTRAINDICATION SIDE NURSING

 RYREY A. PACAMANA BSN 3C DRUG STUDY

FREQUENCY, EFFECTS/ADVERSE
OF ACTION RESPONSIBILITIES
ROUTE EFFECTS
Aspirin Analgesia/Anti- 80 mg Anti- Mild to Contraindicated with Dizziness, tinnitus, Know the 10 Rights in
inflammatory inflammatory moderate pain, allergy to NSAIDs, difficulty hearing, drug administration
OD
and analgesic Inflammatory allergy to atrazine. nausea, vomiting,
Give drug with food or
PO activity; effects conditions. Hemophilia, bleeding diarrhea, mental
after meals if GI upset
are attributable Reduction of ulcers. Hemorrhagic confusion, lassitude
occurs
to aspirin’s risk of states, blood coagulation
ability to inhibit recurrent TIA defects Don’t crush, and
the synthesis of or stroke in ensure that patient
prostaglandins. male w/ does not chew SR
history of TIA preparations
due to fibrin
platelet emboli Monitor for loss of
tolerance to aspirin.
The reaction is
nonimmunologic;
symptoms usually
occur 15 min to 3 h
after ingestion:
profuse rhinorrhea,
erythema, nausea,
vomiting, intestinal
cramps, diarrhea.