This document provides an algorithm for investigating unilateral pleural effusions. The algorithm involves:
1) Determining if the clinical picture suggests a transudate or exudate.
2) Performing pleural aspiration with ultrasound guidance and analyzing the fluid.
3) If not a transudate, considering whether the fluid analysis and clinical features provide a diagnosis. If not, further imaging or procedures may be required.
This document provides an algorithm for investigating unilateral pleural effusions. The algorithm involves:
1) Determining if the clinical picture suggests a transudate or exudate.
2) Performing pleural aspiration with ultrasound guidance and analyzing the fluid.
3) If not a transudate, considering whether the fluid analysis and clinical features provide a diagnosis. If not, further imaging or procedures may be required.
This document provides an algorithm for investigating unilateral pleural effusions. The algorithm involves:
1) Determining if the clinical picture suggests a transudate or exudate.
2) Performing pleural aspiration with ultrasound guidance and analyzing the fluid.
3) If not a transudate, considering whether the fluid analysis and clinical features provide a diagnosis. If not, further imaging or procedures may be required.
Algorithm adapted by permission from BMJ Publishing
Group Limited. Thorax, Hooper C, Lee YCG, Maskell N on behalf of the BTS Pleural Disease Guideline Group, 65 (Suppl 2): ii14-ii7, 2010). *Record initial appearance of fluid (e.g. straw coloured, turbid, blood History, clinical examination and CXR stained).
Does the clinical picture suggest a transudate? E.g. LVF, YES
hypoalbuminaemia, dialysis
NO Treat the cause
Refer to chest physician Resolved?
* Pleural aspiration (with ultrasound guidance). NO YES
Send for cytology, protein, LDH, pH, Gram stain, culture and sensitivity. STOP
Is it a transudate? YES
NO Treat the cause
Has the fluid analysis and clinical features given a
YES diagnosis?
NO Treat appropriately
Request contrast enhanced CT thorax
Consider LA thorascopy or surgical Consider radiological guided pleural biopsy +/-
VATS chest tube drainage if symptomatic
Cause found? YES
NO
Re-consider treatable conditions such as PE, TB, Treat appropriately
chronic heart failure and lymphoma. Watchful waiting often appropriate.