DRUG DOSAGE ACTION OF DRUG INDICATION AND SIDE EFFECT NURSING CONSIDERATION

CONTRAINDICATION
Generic name: epoetin alfa injectable solution Erythropoietin is one factor Anemia cause by reduction CNS: Siezures, coldness, Monitor renal studies,
2000 units/mL (Epogen, controlling rate of red cell endogenous erythropoietin sweating urinalysis, protein, blood, BUN,
Brand name: Eprex Procrit, Retacrit) production; drug is production primarily end creatinine, I&O; report drop in
3000 units/mL (Epogen, developed by recombinant stage renal disease; to CV: Hypertension, output <50 ml/hr
Classification: colony- Procrit, Retacrit) DNA technology correct hemostatic defect in hypertensive encephalopathy
stimulating factors 4000 units/mL (Epogen, uremia Monitor blood studies;
Procrit, Retacrit) MS: Bone pain reticulocyte count weekly:
10,000 units/mL (Epogen, Contraindications: check for symptoms of anemia,
Procrit, Retacrit) Hypersensitivity to albumin, fatigue, pallor, dyspnea
20,000 units/mL (Epogen, hypertension, erythropoietin
Procrit) levels of >200 Mu/ML Assess CNS symptoms; coldness,
40,000 units/mL (Retacrit) sweating
Precautions:
Pregnancy class C Assess CV status: BP before and
during tx; Htn may occur rapidly
leading to Htn encephalopathy

Assess patient during

hemodialysis for bruits, thrills of
shunts; drug prevent severe
anemia in chronic renal failure;
clotting may need to be treated
with increase anticoagulant.

Monitor serum iron levels,

ferritin, transferring levels; iron
therapy may needed to prevent
recurring anemia

Monitor blood studies; BUN,

WBC, phosphorus, potassium,
bleeding time. Hct should be
check in chronic renal failure
Generic name: anti-tetanus booster dose of 0.5 mL of Tetanus Toxoid, for INDICATIONS Adverse reactions may be Shake well the vial before
serum Tetanus Toxoid (tetanus intramuscular or local and include redness, withdrawing each dose
(tetanus toxoid) toxoid) subcutaneous use, is a sterile Tetanus (tetanus toxoid) warmth, edema, induration
Brand name: tetanus toxoid should be given solution of toxoid in isotonic Toxoid is indicated for with or without tenderness Special care should be taken to
intramuscularly every 10 sodium chloride solution. The as well as urticaria, and rash. ensure the injection dose not
General classification: EP
vaccine, anti-tetanus
years to maintain adequate
immunity.
vaccine is clear or slightly
turbid in appearance.
Malaise, transient fever, enter the blood vessel
booster injection only for pain, hypotension, nausea
persons 7 years of age or and arthralgia
older against tetanus
(tetanus toxoid) . This
vaccine is NOT indicated
for primary immunization.

CONTRAINDICATIONS

HYPERSENSITIVITY TO ANY
COMPONENT OF THE
VACCINE, INCLUDING
THIMEROSAL, A MERCURY
DERIVATIVE, IS A
CONTRAINDICATION FOR
FURTHER USE OF THIS
VACCINE.

It is a contraindication to use
this or any other related
vaccine after a serious
adverse event temporally
associated with a previous
dose including an
anaphylactic reaction.

Brand name: Fluimucil.
Generic name:
Acetylcysteine.
Classification: mucolytics.
Adults:
1 sachet of FLUIMUCIL 200
mg or 2 sachets of
FLUIMUCIL 100 mg 2-3 times
a day.
1 FLUIMUCIL 600 mg
effervescent tablet daily
(preferably in the evening)
reduces mucus viscosity
in non-purulent and purulent
lung secretions. The mucolytic
effect of acetylcysteine is
based on hydrolyzing disulfide
bonds in mucus, which break
down the mucus into thinner
units, which are easier to get
out of the body.
INDICATIONS
Treatment of respiratory
affections characterized by
thick and viscous
hypersecretions due to acute
bronchitis, chronic bronchitis
and its exacerbation,
pulmonary emphysema,
mucoviscidosis and
Nausea Before using this medication,
Vomiting ask the patient for any
Urticaria breathing problems (such as
Bronchospasm emphysema, chronic bronchitis,
(difficulty breathing) asthma, smoker's cough), cough
Tightness in chest with blood or large amounts of
Flu-like symptoms mucus, liver problems.
(runny nose and fever)
Rapid heart rate
Monitor for allergic reaction

For the prevention of
exacerbation, the use of
FLUIMUCIL 200 mg sachet is
recommended.
Children:
1 sachet of FLUIMUCIL 100
mg, 2 to 4 times a day,
according to age
Generic Name: atenolol  Blocks beta-
 Available forms:
Brand Name: Apo-Atenolol Tablets—25, 50, 100
(CAN), Gen-Atenolol (CAN), mg; injection—5 mg/10
Novo-Atenol (CAN), mL
Tenormin  Hypertension:
Classification: Beta1- Initially, 50 mg PO once
selective adrenergic a day; after 1–2 wk,
blocker, Antianginal, dose may be increased
to 100 mg/day.
Antihypertensive
 Angina pectoris:
Initially, 50 mg PO daily.
Pregnancy Category D
If optimal response is
not achieved in 1 wk,
increase to 100 mg
daily; up to 200 mg/day
may be needed.
 Acute MI: Initially, 5
mg IV given over 5 min
as soon as possible after
diagnosis; follow with IV
injection of 5 mg 10 min
later. Switch to 50 mg
PO 10 min after the last
IV dose; follow with 50
mg PO 12 hr later.
Thereafter, administer
100 mg PO daily or 50
bronchiectasis. (tachycardia)
Low blood pressure Discuss the risks and benefits
and high blood pressure with your doctor before breast-
CONTRAINDICATIONS Low potassium level feeding.
Known hypersensitivity to Joint pain
acetylcysteine. Fluimucil Blurred vision
granules and tablets are
contraindicated in patients
suffering from
phenylketonuria due to the
aspartame content.
 Allergic reactions: Assessment
adrenergic receptors of
Indications Pharyngitis,
the sympathetic erythematous rash,  History: Sinus
 Treatment of angina
nervous system in the fever, sore throat, bradycardia, second- or
pectoris due to coronary
heart and laryngospasm, third-degree heart block,
atherosclerosis
juxtaglomerular respiratory distress cardiogenic shock, CHF,
 Hypertension, as a
apparatus (kidney), thus  CNS: Dizziness, renal failure, diabetes or
step 1 agent, alone or
decreasing the vertigo, tinnitus, fatigue, thyrotoxicosis, lactation,
with other drugs,
excitability of the heart, emotional depression, pregnancy
especially diuretics
decreasing cardiac paresthesias, sleep  Physical: Baseline
 Treatment of MI
output and oxygen disturbances, weight, skin condition,
 Unlabeled uses:
consumption, hallucinations, neurologic status, P, BP,
Prevention of migraine
decreasing the release disorientation, memory ECG, respiratory status,
headaches; alcohol
of renin from the loss, slurred speech renal and thyroid function
withdrawal syndrome,
kidney, and lowering BP.  CV: Bradycardia, CHF, tests, blood and urine
treatment of ventricular
cardiac arrhythmias, glucose, cholesterol,
and supraventricular
sinoatrial or AV nodal triglycerides
arrhythmias
block, tachycardia, Interventions
 Other: Decreased
peripheral vascular
exercise tolerance,  WARNING: Do not
insufficiency, discontinue drug abruptly
development of
claudication, CVA,
antinuclear antibodies, after long-term therapy
pulmonary edema, (hypersensitivity to
hyperglycemia or
hypotension
hypoglycemia, elevated catecholamines may have
 Dermatologic: Rash, developed, causing
serum transaminase,
pruritus, sweating, dry
alkaline phosphatase, exacerbation of angina, MI,
skin and ventricular
and LDH
 EENT: Eye irritation, arrhythmias). Taper drug
dry eyes, conjunctivitis,
 mg PO bid for 6–9 days
or until discharge from
Contraindications
the hospital
 Contraindicated with
sinus bradycardia,
second- or third-degree
heart block, cardiogenic
shock, CHF, pregnancy.
 Use cautiously with
renal failure, diabetes or
thyrotoxicosis (atenolol
can mask the usual
cardiac signs of
hypoglycemia and
thyrotoxicosis),
lactation, respiratory
disease.
Generic Name: Bactericidal: Inhibits INDICATION
Cefuroxime Actual: 750mg q8⁰ ANST synthesis of bacterial cell For treatment of many
wall, causing cell death. different types of bacterial
infections such as bronchitis,
blurred vision
 GI: Gastric pain,
flatulence, constipation,
diarrhea, nausea,
vomiting, anorexia,
ischemic colitis, renal
and mesenteric arterial
thrombosis,
retroperitoneal fibrosis,
hepatomegaly, acute
pancreatitis
 GU: Impotence,
decreased libido,
Peyronie’s disease,
dysuria, nocturia,
frequent urination
 Musculoskeletal:
Joint pain, arthralgia,
muscle cramps
 Respiratory:
Bronchospasm,
dyspnea, cough,
bronchial obstruction,
nasal stuffiness, rhinitis,
pharyngitis (less likely
than with propranolol)
 Other: Decreased
exercise tolerance,
development of
antinuclear antibodies,
hyperglycemia or
hypoglycemia, elevated
serum transaminase,
alkaline phosphatase,
and LDH
 Mucus rush
 Rash
 Difficulty in
gradually over 2 wk with
monitoring.
 Consult physician about
withdrawing drug if patient
is to undergo surgery
(withdrawal is
controversial).
Teaching points
 Take drug with meals if
GI upset occurs.
 Do not stop taking this
drug unless told to do so
by a health care provider.
 Avoid driving or
dangerous activities if
dizziness or weakness
occurs.
 You may experience
these side effects:
Dizziness, light-
headedness, loss of
appetite, nightmares,
depression, sexual
impotence.
 Report difficulty
breathing, night cough,
swelling of extremities,
slow pulse, confusion,
depression, rash, fever,
sore throat.
Assess any history of allergy
with this drug.
Culture infection, and arrange
Brand Name: Ideal: PO: 250mg BID 7-10 sinusitis, tonsillitis, ear
Ceftin days or infection, skin infections,
gonorrhea, and urinary tract
Classification: Antibiotic IV: 750mg BID infection.
,Cephalosporin
CONTRAINDICATION
Contraindicated with allergy
cephalosporin or penicillins.
Use cautiously with renal
failure, lactation, pregnancy.
breathing for sensitivity tests before and
 Unusual tiredness during therapy if expected
 Fatigue response is not seen.
 Itching or irritation
Give oral drug with food to
decrease GI upset and enhance
absorption.
Have vit. K available in case
hypoprothrombinemia occurs.
Instruct the pt to report any
unusualities.