Abstracts / Journal of the Neurological Sciences 405S (2019) 116541 131
Parametric survival analysis is one of the survival analysis that WCN19-1766
has a distribution of survival data that follows a certain distribution. Weibull distribution is a distribution that is often used in parametric Journal of the Neurological Sciences 405S (2019) 104348 survival analysis. The purpose of this study is to determine parametric survival models using the Weibull distribution and to determine the factors that can influence the recovery of stroke Poster Session 1 patients. This study uses data on stroke patients in the Sultan Daeng Raja Hospital, Bulukumba, Sulawesi Selatan, Indonesia in 2018. The High frequency RTMS on cortical reorganization of chronic stroke best model obtained in this study is a model that consists of two predictor variables, namely the age and the body mass index (BMI). N. Kuthiala, P. Srivastava MV, R. Sharma, S. Sharma Therefore the factors that can influence the recovery of stroke All India Institute of Medical Sciences, Neurology, New Delhi, India patients are age and BMI. Background doi:10.1016/j.jns.2019.10.684 The purpose of the study was to investigate the effect of high frequency rTMS with Rehabilitation on cortical reorgani- zation of chronic stroke patients with upper extremity motor deficits. fMRI as a technique provides a window into functional WCN19-1759 activity in multiple brain areas, and has good accessibility, safety, and spatial resolution. The evidence of cortical reorga- nization was used to assess in response to intensive physio- Journal of the Neurological Sciences 405S (2019) 104347 therapy treatment with rTMS using blood oxygenation-level dependent (BOLD) Poster Session 1 Methodology The complex approach to the rehabilitation of patients with This study is a RCT. This included (N=60) chronic stroke motor deficit in the early recovery period of ischemic stroke patients from 3 to 18 months of index event. Patients were randomized to CIMT alone (Group A n=30) & rTMS with CIMT F. Devlikamovaa, F. Khabirova, T. Khaibullina, E. Granatovb (Group B n=30). rTMS (10 Hz, 750 pulses with 110%RMT) was a Kazan State Medical Academy, Department of Neurology, Kazan, Russia administered for 3 weeks (5days/week). Radiological Assessment b Republican Clinical Neurological Center, Department of Neurophysiol- of the patients was done with fMRI (BOLD) along with assessment ogy, Kazan, Russia of Fugl Meyer (FM), Barthel Index, and modified Rankin Scales, at baseline, 15th & 90th day We aimed to evaluate the efficacy of complex rehabilitation: kinesiotherapy, navigation TCMS (nTCMC), and Cerebrolysin (neu- Results ropeptide preparation drug proved to contain fragments of neuro- The mean FMA score at baseline, 15th and 90th day in Group A trophic factors), in patients with ischemic stroke (IS). was 34.53+6.02, 42.47+6.1, 42.50+6.0 in comparison to Group B 110 patients (34–71 years) with IS and motor deficit (at least 2 34.07+6.4, 51.47+7.7&52.07+7.6 showing the significant im- points on motor functions of the NIHSS) were randomized into 4 provement (pb.000) in Group B. there was no statistical significant groups (G): G1 (n = 33) only kinesiotherapy (PNF, 1 session/day, 14 improvement seen in other two scales. The BOLD cluster activation days); G2 (n = 32) kinesiotherapy and cerebrolysin (20.0 ml IV was compared between two groups. daily, 14 days); G3 (n = 25) kinesiotherapy and nTCMS (precentral gyrus, 5 Hz, 5 sec., 20 sec. rest, 500 pulses, 1 session/day, 14 days); Conclusion G4 (n = 20) kinesiotherapy, cerebrolysin, nTCMS. Indicators (EEG, Alterations in cortical activations (fMRI-BOLD) was observed after STREAM, Bartel Index) were evaluated at the beginning of treatment intensive rehabilitation with rTMS (Group B) in patients with and after 6 months. chronic stroke. Activation and functional changes in fMRI and TMS The nonparametric Kruskal-Wallis ANOVA statistics showed most correlated significantly with the degree of clinical improvement in pronounced recovery in G4 (p b0.05): STREAMS (Me [LQ; UQ] - 17 upper extremity function. [12,5; 22], 19 [14; 24], 23 [18; 25,5], 29 [26; 31] points in G1-4) and the Bartel Index (Me [LQ; UQ] - 75 [60; 80], 75 [65; 80], 80 [70; 85], 90 [85; 95] points in G1-4). Most pronounced decrease in the doi:10.1016/j.jns.2019.10.686 spectral power of the delta rhythm and the increase in the spectral power of the alpha rhythm in the affected hemisphere were observed in G4 (391, 355, 394, 234 and 101, 111, 96, 131 μV2/ Hz in G1-4 (p b0.05). WCN19-1777 The complex combination therapy including kinesiotherapy, nTCMS, and cerebrolysin proved to be most effective in restoring motor Journal of the Neurological Sciences 405S (2019) 104349 disorders and normalizing the functional state of the brain
Poster Session 1
doi:10.1016/j.jns.2019.10.685 ‘Prehospital’ delay in acute stroke reperfusion therapy in Delhi: