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  • Pathophysiology: Incubation Stage

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    William Soneja Calapini
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    The document discusses the pathophysiology of measles. It begins by listing precipitating and predisposing factors such as travel to areas where measles is endemic, age, pregnancy, and vitamin A deficiency. It then describes the modes of transmission as droplets of saliva, touching contaminated surfaces, skin to skin contact, and from mother to baby during pregnancy. The mechanism of measles is then outlined in stages: incubation, primary and secondary viremia, prodromal stage with symptoms like fever and Koplik's spots, exanthem stage with rash progression, and recovery stage with lasting immunity.

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    Measles Pathophysiology

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    The document discusses the pathophysiology of measles. It begins by listing precipitating and predisposing factors such as travel to areas where measles is endemic, age, pregnancy, and vitamin A deficiency. It then describes the modes of transmission as droplets of saliva, touching contaminated surfaces, skin to skin contact, and from mother to baby during pregnancy. The mechanism of measles is then outlined in stages: incubation, primary and secondary viremia, prodromal stage with symptoms like fever and Koplik's spots, exanthem stage with rash progression, and recovery stage with lasting immunity.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    209 views3 pages

    Pathophysiology: Incubation Stage

    Uploaded by

    William Soneja Calapini
    The document discusses the pathophysiology of measles. It begins by listing precipitating and predisposing factors such as travel to areas where measles is endemic, age, pregnancy, and vitamin A deficiency. It then describes the modes of transmission as droplets of saliva, touching contaminated surfaces, skin to skin contact, and from mother to baby during pregnancy. The mechanism of measles is then outlined in stages: incubation, primary and secondary viremia, prodromal stage with symptoms like fever and Koplik's spots, exanthem stage with rash progression, and recovery stage with lasting immunity.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 3

    PATHOPHYSIOLOGY

    (Measles)

    Precipitating Factors:
    Travel to a place where measles is endemic
    Predisposing Factors: Visit’s areas where measles is occurring
    Age
    Contacts with someone who has measles.
    People with compromised immune systems
    Not receiving a measles vaccine.
    Pregnant Women
    Vitamin A deficiency

    Mode of Transmission
    Droplets of saliva
    By touching contaminated surface
    Skin to skin
    Mother to baby though pregnancy.

    Port of Entry
     Nose
     Eyes
     Mouth

    Mechanism of Measles

    Incubation Stage
    (10-14 days)

    Virus multiplies in the epithelial cells


    Primary Viremia

    The virus continues to replicate in the epithelial


    cells and Reticuloendothelial system

    Secondary Viremia

    Symptoms Appear

    Prodromal Stage
    (2-4 days) Fever, Malaise, Anorexia
    Along w/: Cough, Conjunctivitis, Coryza

    Koplik's spots
    Erythematous, maculopapular, blanching rash

    Exanthem Stage
    (2-4 days after fever)

    Cephalocaudal progression

    Persistent Cough

    Recovery Stage
    (7-14 days)
    Skin rashes will fade

    Lifelong immunity

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