Download as pdf or txt
Download as pdf or txt
You are on page 1of 14

International Journal of Nursing Studies 51 (2014) 136–149

Contents lists available at SciVerse ScienceDirect

International Journal of Nursing Studies


journal homepage: www.elsevier.com/ijns

Review

Impact of e-learning on nurses’ and student nurses knowledge, skills, and


satisfaction: A systematic review and meta-analysis
Mari Lahti a,*, Heli Hätönen a, Maritta Välimäki b
a
University of Turku, Faculty of Medicine, Department of Nursing Science, Turku, Finland
b
Southwest Hospital District, Turku, Finland

A R T I C L E I N F O A B S T R A C T

Article history: Objective: To review the impact of e-learning on nurses’ and nursing student’s knowledge,
Received 5 February 2012 skills and satisfaction related to e-learning.
Received in revised form 18 November 2012 Design: We conducted a systematic review and meta-analysis of randomized controlled
Accepted 19 December 2012 trials (RCT) to assess the impact of e-learning on nurses’ and nursing student’s knowledge,
skills and satisfaction. Electronic databases including MEDLINE (1948–2010), CINAHL
Keywords: (1981–2010), Psychinfo (1967–2010) and Eric (1966–2010) were searched in May 2010 and
e-Learning again in December 2010. All RCT studies evaluating the effectiveness of e-learning and
Nurse
differentiating between traditional learning methods among nurses were included.
RCT
Data extraction and quality assessment: Data was extracted related to the purpose of the trial,
Traditional learning
sample, measurements used, index test results and reference standard. An extraction tool
developed for Cochrane reviews was used. Methodological quality of eligible trials was
assessed.
Data synthesis: 11 trials were eligible for inclusion in the analysis.
Results: We identified 11 randomized controlled trials including a total of 2491 nurses and
student nurses’. First, the random effect size for four studies showed some improvement
associated with e-learning compared to traditional techniques on knowledge. However,
the difference was not statistically significant (p = 0.39, MD 0.44, 95% CI 0.57 to 1.46).
Second, one study reported a slight impact on e-learning on skills, but the difference was
not statistically significant, either (p = 0.13, MD 0.03, 95% CI 0.09 to 0.69). And third, no
results on nurses or student nurses’ satisfaction could be reported as the statistical data
from three possible studies were not available.
Conclusion: Overall, there was no statistical difference between groups in e-learning and
traditional learning relating to nurses’ or student nurses’ knowledge, skills and
satisfaction. E-learning can, however, offer an alternative method of education. In future,
more studies following the CONSORT and QUOROM statements are needed to evaluate the
effects of these interventions.
ß 2013 Elsevier Ltd. All rights reserved.

What is already known about the topic?

 The use of e-learning and computer assisted methods is


* Corresponding author at: University of Turku, Department of Nursing rapidly increasing in medical and nursing education.
Science, Vartiovuorenkatu 3Ba22, 20700 Turku, Finland.  The use of innovative learning methods has been shown
Tel.: +358 41 458 14 55.
to be promising in medicine to improve knowledge
E-mail addresses: melaht@utu.fi, marielinalahti@gmail.com
(M. Lahti).
among learners.

0020-7489/$ – see front matter ß 2013 Elsevier Ltd. All rights reserved.
http://dx.doi.org/10.1016/j.ijnurstu.2012.12.017
M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149 137

 There is still a lack of evidence about the impact of interventions. They showed that interactivity, practice
computer assisted and e-learning methods in nursing exercises, repetition, and feedback improved learning
education. outcomes while using e-learning interventions (Cook
et al., 2010b).
However, reviews of the effectiveness of e-learning
What this paper adds
have focused mostly on professionals working in the field
of medicine or health care in general (Cook et al., 2008,
 There is a lack of systematically conducted RCT studies
2010a; Curran and Fleet, 2005; Cobb, 2004; Wutoh et al.,
comparing the effects of e-learning and traditional
2004). To the best of our knowledge only one review has
learning methods in nursing education.
been conducted on e-learning in general (Schittek et al.,
 In nursing education, e-learning is not superior to
2001). No systematic reviews of e-learning and its
traditional learning method but can be used as an
effectiveness have been done among nurses or student
alternative method in nursing education.
nurses by meta-analytic methods although nurses are one
 e-Learning should be used with a good understanding of
of the largest groups of professionals in health care
learners’ needs.
(Eurostat, 2011). Therefore it is important to focus on
the impacts of e-learning on this professional group. In
1. Introduction addition, as in the concern expressed by Curran and Fleet
(2005), Curran et al. (2010), too often evaluative education
Lifelong learning is one of the priorities in the European studies rely on participants’ satisfaction level while more
educational area (European Commission, 2010). Informa- energy should be put into knowledge transfer, skills
tion and communication technology (ICT) opens doors to improvement and the changes in practice after educational
new innovative methods to deliver education across the interventions. The importance of focusing on a variety of
lifespan (European Commission, 2011). The use of e- outcomes when evaluating educational training such as e-
learning is a rapidly growing form of education and a new learning is also noted in Kirkpatrick’s model of learning
way of delivering education in general (Digital Agenda outcome evaluation (Galloway, 2005). Kirkpatrick’s model
Assembly, 2011; Commission of the European Commu- has four levels to evaluate educational training: (1)
nities, 2000, 2001, 2003). This is also the case in health reaction, i.e. student satisfaction, (2) learning, i.e. knowl-
care, where the Internet and Worldwide Web (WWW) edge increase, (3) behavior, i.e. change in practice and (4)
have expanded the opportunities for flexible, convenient, results, i.e. final outcomes (Kirkpatrick, 1998; Galloway,
and interactive education (Cook et al., 2010a, 2008; Belcher 2005). Therefore the focus in this review was on the impact
and Vonderhaar, 2005; Wutoh et al., 2004) for educational of e-learning on knowledge, skills and satisfaction among
provision and health care professionals (Lowry and nurses and nursing students.
Johnson, 1999).
e-Learning has been described as a dynamic, innovative 2. Objective
and rich way to provide learning opportunities (Belcher
and Vonderhaar, 2005). Students can access a class through This systematic review aims to investigate the impact of
a website and participate in lectures and group discussion e-learning on knowledge, skills and satisfaction among
in real time. Materials may also be provided asynchro- nurses and nursing students compared to traditional
nously; students access the website, follow lectures or education methods.
complete assignments according to their own schedules
(Simpson, 2003.) In the recent literature there are a few 3. Methods
systematic reviews of research on e-learning (Cook et al.,
2008, 2010a,b; Curran and Fleet, 2005; Cobb, 2004; Wutoh The research consists of a systematic review (Higgins
et al., 2004; Schittek et al., 2001). In general, the benefits and Green, 2011).
reported for e-learning are flexibility, accessibility, satis-
faction and cost-effectiveness (Smith, 2005; Wutoh et al., 3.1. Data sources and searches
2004; Ward et al., 2008). A meta-analysis by Cook et al.
(2010a) showed that e-learning can increase students’ own We electronically searched MEDLINE (1948–2010),
control over the content, place and time of learning. CINAHL (1981–2010), PsychInfo (1967–2010), Eric
Furthermore, it can help students gain knowledge and (1966–2010) for publications in English in May 2010.
skills faster than traditional instructor-led methods (Cook The search was updated in December 2010. No restrictions
et al., 2008). were placed on date of publications and each database was
The review by Cook et al. (2008) and Wutoh et al. (2004) searched as far back as possible (Savoie et al., 2003). This is
focused on the effectiveness of e-learning. Cook et al. recommended method when search terms has varied in
(2008) reported positive results in their meta-analysis past history or showed a huge diversity which is the
comparing e-learning intervention to non-intervention. situation with the concept of the e-learning (Egger et al.,
Wutoh et al. (2004) also report in their review that e- 1997).
learning for delivering continuing medical education is as As each database has its own unique indexing terms,
good as other methods in transferring knowledge. In individual search strategies were developed for each
addition, Cook et al. (2010b) compared e-learning inter- database. Consideration was given to the diverse termi-
ventions to other types of computer based educational nology used for e-learning as this would influence the
138 M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149

identification of relevant trials. Focus was in finding a 3.4. Assessment of the methodological quality of the included
relevant MeSH terms or Subject Headings in different trials
databases related to this topic as e-learning is not a listed for
Subject Heading. Medical informatics was also consulted to The methodological quality of the included studies was
ensure that the right search terms were used. The search assessed using process and criteria based on those of the
strategy used in English was as follows: ‘‘(Computer- Cochrane Collaboration Handbook for Systematic Reviews
Assisted Instruction/or computer assisted.mp. or online.mp. of Interventions (Higgins and Green, 2011). This assesses the
or www.mp. or internet.mp. or Internet/or computer methodological quality in the following six domains: (1)
based.mp.) and (learning/or problem-based learning/or Sequence generation – was the allocation sequence
problem solving/or learn*.ti,ab. or cal.ti,ab. or Knowledge/ adequately generated? (2) Allocation concealment – was
or knowledge.ti,ab.) and (psychiatric nurs*.mp. or Psychia- allocation adequately concealed? (3) Blinding of partici-
tric Nursing/or Nurses/or nurse*1.ti,ab.) and (Random pants – was adequate knowledge of the allocated interven-
Allocation/or random*.mp. or randomized controlled tion adequately concealed from the outcome assessors? (4)
trial.pt.) limit to (abstracts and English language) (Savoie Incomplete outcome data – was this adequately addressed
et al., 2003; University of York, 2008). ‘‘Psychiatric’’ was for each outcome (this includes differential attrition
included as a search term to ensure that all relevant between groups)? (5) Selective outcome reporting – are
literature will be achieved. In addition, the reference lists the reports of the study free from suggestions of selective
and bibliographies of retrieved articles were reviewed to outcome reporting? 6) Other sources of bias – was the study
identify any additional items. To complement the search apparently free from other problems that could subject it to
strategies keyword searching of the World Wide Web and put it at a high risk of bias? The methodological quality of
Cochrane Library was also conducted (Khan et al., 2003). these domains was assessed by using following scoring: (1)
‘low risk of bias’, when plausible bias unlikely alter the
3.2. Inclusion criteria results, (2) ‘unclear risk of bias’ when plausible bias raises
some doubt about the results and (3) ‘high risk of bias’ when
We used pre-defined criteria to include studies in our plausible bias seriously weakens confidence in the results
review and studies fulfilling these criteria were included. (Higgins and Green, 2011).
We included studies with nurses or nursing students used To deal with publication bias the Cochrane Handbook
as a study population. The intervention used was e- for Systematic Reviews of Intervention (Higgins and Green,
learning. It was defined as computer assisted learning, use 2011) was used to guide the process. Attempts to locate the
of CD-ROM and online learning as these would refer to be protocols of the studies included were made, but none of
nuanced variations for e-learning, while traditional the studies included had a protocol. As no protocols were
education included contact teaching, classroom lecturing, used, lists of outcomes mentioned in the method section
and text-based learning. Outcomes listed were increase of were used in the study and compared to the results
knowledge and skills and satisfaction (Khan et al., 2003; actually reported. The methodological quality of eligible
University of York, 2008). trials was assessed independently by three reviewers (ML,
To be included, the studies had to be randomized HH, MV).
controlled trials (RCT), controlled clinical trials (CCT),
controlled before and after (CBA) studies using e-learning 3.5. Quantitative data synthesis
among nurses or nursing students. We excluded studies
using simulation, mobile phones and mannequins, like- The data from the studies included were entered into
wise studies not published in English (Khan et al., 2003). Review Manager 5.1 (RevMan), which is the software used
for preparing and maintaining Cochrane Reviews. The data
3.3. Data extraction analysis was divided into two phases. First, the analysis
explored the descriptive characteristics of the individual
The extraction tool developed for Cochrane reviews was studies included. Second, for continuous outcomes we
used. A reviewer (ML) independently extracted data estimated mean difference (MD) between groups (Moore
related to the following issues: purpose of the trial, and McCabe, 2003). When scales of very considerable
sample, details of the intervention, outcomes and mea- similarity such as knowledge tests were used, we
surements used, follow-up time, index test results and presumed there was a small difference in measurement
reference standard. If any data were missing from the and combined the measures. This decision was made to
report of the trial, attempts were made to obtain these by answer the overall question of whether there is evidence
contacting the authors. Each citation was then assessed that e-learning can work (Higgins and Green, 2011). In this
against the inclusion/exclusion criteria independently by approach standard deviations were used together with the
one reviewer (ML). The full texts of studies eligible for the sample sizes to compute the weight given to each study. In
review were then obtained. For studies with unclear titles general, studies with small standard deviations are given
and abstracts, the full text was also obtained. Decisions to relatively higher weight while studies with larger standard
include a publication in the review were made by the deviations are given relatively smaller weights. This is
reviewers (ML, MV, HH). This was followed by evaluation appropriate if the variation in standard deviations between
of the full text of all papers retrieved. In case of any studies reflects differences in the reliability of outcome
disagreement the paper was discussed with other member measurements (Higgins and Green, 2011). Then we
of research group (Khan et al., 2003). calculated effect sizes from mean differences of post test
M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149 139

scores (Ray and Shadish, 1996). Random effect was used 4. Results
instead of fixed effect because random effect allows the
outcomes of studies to vary more than fixed effects. In 4.1. Trial flow
other words, random effects can be seen to be a more
A meta-analysis profile summarizing the flow diagram
natural way of explaining outcome (Ades and Higgins,
is presented in Fig. 1.
2005). Heterogeneity was checked by calculating using I2 –
A total of 158 publications were identified from the
square statistics. This provides an estimate of the
databases. A review of the reference lists and bibliogra-
percentage of variability due to heterogeneity rather than
phies of the items retrieved identified 19 additional clinical
change alone. Where the I2 – square estimated was greater
trials relevant to the topic. Out of the 177 publications, 26
than or equal to 50%, it was interpreted as indicating the
were duplicates. All together from 151 publications, 132
presence of high levels of heterogeneity (Higgins and
publications were excluded because they did not meet the
Green, 2011; Higgins et al., 2003; Higgins and Thompson,
inclusion criteria. Thus, 19 studies were read in full. Eight
2002).
studies were excluded due to wrong population (n = 3) and
No assumptions about loss to follow-up were made for
a lack of randomized design (n = 5). Thus a total of 11
continuous data and the results were analyzed for those
studies were included in the quantitative data analysis
who completed the trial, since the use of methods such as
(Fig. 1).
the last observation carried forward (LOCF) introduce
uncertainty about the reliability of any result (Leucht et al., 4.2. Methodological quality of the included trials
2007). The high number of the loss to follow-up can be a
threat for the validity of the results. However, even The methodological quality of the 11 publications
relatively high rates of loss to follow-up will result bias included in the review varied. Incomplete details in
only if the number lost is imbalanced between groups reporting the sequence generation and allocation con-
(Guyatt et al., 2011). cealment were the main reasons for decreasing the
Idenficaon

Records idenfied through Addional records idenfied


database searching through other sources
(n = 158) (n = 19 )

Records all together


(n = 177)

Records aer duplicates removed


Screening

(n = 151)

Records screened by tle Records excluded by tle


(n = 151) (n = 89)

Records screened by Records excluded by abstract


abstract (n = 43)
Eligibility

(n = 62)

Full-text arcles assessed Full-text arcles excluded,


for eligibility with reasons
(n = 19) (n = 8)
Included

Studies included in
quantave synthesis
(meta-analysis)
(n = 11)

Fig. 1. Flow diagram (Moher et al., 2009).


140 M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149

studies used a parallel study design. However, one


employed a cross-over design (Cega et al., 2007)
(Table 1). Power calculations were conducted in two
studies (Cega et al., 2007; Paladino and Peres, 2007), and
one study (Horiuchi et al., 2009) reported some guidance
used to calculate adequate power for the sample size.
However, eight studies did not report any power calcula-
tion to estimate the adequate sample size. Nevertheless,
meta-analysis of individual studies used in this review
increases statistical power by reducing the standard error
of the weighted average effect size (Cohn and Becker,
2003).
Information about participants totaled 2491 nurses and
nursing students. Three of the studies included had
student nurses’ (n = 618) (Beeckman et al., 2008; Bloom-
field et al., 2010; Cega et al., 2007) and eight of them had
nursing staff (n = 1873) (Bloomfield et al., 2010; Harrington
and Walker, 2004, 2006; Hsiao Sheen et al., 2008; Irvine
et al., 2007; Mcvey et al., 2009; Paladino and Peres, 2007;
Tsai et al., 2004). Overall, the study size varied from 42
(Hsiao Sheen et al., 2008) to 1294 (Harrington and Walker,
2004) participants (Table 1).
Three studies used previously tested and validated
outcome measurements (Bloomfield et al., 2010; Cega
et al., 2007; Harrington and Walker, 2004) and one study
used partially validated measurement (Mcvey et al., 2009).
Seven studies used self-developed instrument, i.e. a
questionnaire developed for that particular study. Nine
studies had primary outcome measure as knowledge
(Bloomfield et al., 2010; Cega et al., 2007; Harrington and
Walker, 2004, 2006; Horiuchi et al., 2009, Irvine et al.,
2007, Mcvey et al., 2009; Paladino and Peres, 2007; Tsai
et al., 2004), while two studies had nursing skills as a
primary outcome (Beeckman et al., 2008; Hsiao Sheen
et al., 2008) (Table 1). All outcome measurements used the
same kind of scoring where higher score indicates better
knowledge or skills achieved.

4.4. Description of the interventions

Studies included in the review used variety of different


interventions. However, all interventions used either a
computer program (Bloomfield et al., 2010; Cega et al.,
Fig. 2. Risk of bias based on Cochrane Systematic Reviews of Interventions 2007; Harrington and Walker, 2004, 2006; Tsai et al., 2004)
(Higgins and Green, 2011). or e-learning (Beeckman et al., 2008; Horiuchi et al., 2009;
Hsiao Sheen et al., 2008; Irvine et al., 2007; Mcvey et al.,
methodological quality of included studies. None of the 2009; Paladino and Peres, 2007). The purpose for inter-
studies were blinded or no attempt was made at blinding. vention programs was to educate nurses and student
This may be due to the nature of the intervention, where nurses using different contents. Learning methods also
blinding would be difficult to achieve. In addition, varied regarding delivering the course, and in the text and
incomplete details in selective outcome reporting low- multimedia methods used, such as plain text, Power-
ered the quality as none of the studies reported the use of PointTM (a product by Microsoft1), video, film, graphics,
protocols. However, this was assessed as ‘low risk of bias’ pictures, or images. All interventions were relatively short
because it was assumed that the published reports between 40 min to 330 min. One study reported duration
included all outcomes (Higgins and Green, 2011) (Fig. 2). of 60 days for an intervention (Mcvey et al., 2009) (Table 2).
Eight studies out of 11 (Beeckman et al., 2008;
4.3. Study characteristics Bloomfield et al., 2010; Cega et al., 2007; Harrington and
Walker, 2004; Horiuchi et al., 2009; Hsiao Sheen et al.,
This review includes 11 studies published between 2008; Paladino and Peres, 2007; Tsai et al., 2004) used
2004 and 2010. All studies were reportedly randomized, traditional teaching as a comparison for e-learning
although the description of the allocation varied. All 11 intervention. Traditional teaching was mainly done using
Table 1
Characteristics of included studies (N = 11).

Authors Title Methods Participants Outcome

Beeckman et al. (2008) Pressure ulcer’s: e-Learning to improve Allocation: Randomized, computer Participants: Nursing students (final Data not able to use:
classification by nurses and nursing generated sequences year), qualified nurses 1. Classification skills for pressure
students Blindness: No N: 426, nurses 212, students 214 ulcers
Design: Parallel Age: 25–44
Location: Multicenter Gender: Female
Setting: Private computer classroom,
traditional classroom
Excluded: No further detail

Bloomfield et al. (2010) The effect of computer-assisted Allocation: Randomized, computer Participants: Nursing students (first Data not able to use:

M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149


learning versus conventional teaching generated sequences year) 1. Knowledge gain,
methods on the acquisition and Blindness: Assignment concealed until N: 231 2. Skill performance checklist
retention of hand washing theory and after all participants had been recruited Age: 17–15
skills in pre-qualification nursing Design: Parallel Gender: Female n = 193, Male n = 38
students: A randomized controlled trial Location: Single located Setting: Individual computer terminal
in an on-campus computer-room,
clinical skills room
Excluded: No further details

Cega et al. (2007) Computer-aided vs. tutor delivered Allocation: Randomized, allocated using Participants: Nursing students (third 1. Knowledge gain (MCQ1, MCQ2)
teaching of exposure therapy for computer-generated tables year and second year) 2. Skills application (two cases
phobia/panic: Randomised controlled Blindness: No N: 92 scenarios)
trial with pre-registration nursing Design: Parallel, cross over Age: Mixed age
students Location: Single located Gender: Mixed gender
Setting: Individual computer terminal
in a classroom, traditional classroom
Excluded: No further details

Harrington and The effects of computer-based training Allocation: Random assignment Participants: Staff of nursing facilities Data not able to use:
Walker (2004) on immediate and residual learning of Blindness: No N: 1294 1. Knowledge gain – Knowledge on fire
nursing staff Design: Parallel Age: Mean age 44 safety
Location: Multicentre Gender: Female n = 1109, Male n = 185 2. Attitudes towards fire safety
Setting: Nursing facilities 3. Prevention practices related to fire
Excluded: No further details safety
4. Usefulness of the program, content
and format

Harrington and Teaching ergonomics to nursing facility Allocation: Random assignment Participants: Nursing facility managers 1. Knowledge gain – staff knowledge
Walker (2006) managers using computer-based Blindness: No N: 45 related to ergonomics
instruction Design: Parallel Age: Mean age 45 2. Staff attitudes related to ergonomics
Location: Multicentre Gender: Female n = 33, Male n = 12 3. Staff practices related to ergonomics
Setting: Nursing facilities Data not able to use
Excluded: No further details 4. Usefulness of the program
5. Effectiveness of the user-interface

141
142
Table 1 (Continued )

Authors Title Methods Participants Outcome

Horiuchi et al. (2009) Evaluation of a web-based graduate Allocation: Randomized, computer Participants: Registered nurses or 1. Knowledge gain – knowledge test
continuing education program in generated sequences midwifes 2. Course evaluation Data not able to
Japan: a randomized controlled trial Blindness: No N: 70 use
Design: Parallel Age: Mean age 34 3. Satisfaction with learning modality
Location: Multicentre Gender: Female n = 69, Male n = 1
Setting: Web-based learning access on
the course at home or workplace, face-
to-face lectures in nursing school
Excluded: No further details

Hsiao Sheen et al. (2008) e-Learning education programme for Allocation: Randomly allocated by Participants: Registered nurses Data not able to use:
registered nurses: the experience of a flipping a coin N: 42 1. Nursing care skill test

M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149


teaching medical center Blindness: No Age: Mean age 31 2. Attitudes towards the programmed
Design: Parallel Gender: Females 42
Location: Single located Setting: Intervention in hospital
intranet, in computer class, comparison
no further details
Excluded: Nurses who did not complete
either ELEP or TICP during the study

Irvine et al. (2008) Internet training for nurse aides to Allocation: Random assignment Participants: Professional 1. Knowledge gain – VST responses to
prevent resident aggression Blindness: No caregivers = nurse aides videos of aggressive situations
Design: Parallel N: 72, 62 completed 2. Self-efficacy
Location: Single located Age: Over 18 3. Attitude
Gender: Female n = 53, Male n = 9 4. Behavioral intention
Setting: Internet
Excluded: No further detail

Mcvey et al. (2009) A controlled evaluation of web-based Allocation: Randomly allocated by coin Participants: Elementary school 1. Knowledge gain
training for teachers and public health Blindness: No teachers and public health practitioners 2. Efficacy to fight weight bias Data not
practitioners on the prevention of Design: Parallel N: 165 (teachers 78, health able to use
eating disorder Location: Multicentre practitioners 89) 3. Computer and internet use
Age: Not described 4. Satisfaction
Gender: Female n = 147, Male n = 30
Setting: Not described
Excluded: No further details

Paladino and Peres (2007) e-Learning: A comparative study for Allocation: Random assignment Participants: Registered nurses 1. Knowledge gain – Knowledge test
knowledge apprehension among Blindness: No N: 49 about quality tool
nurses Design: Parallel Age: Not described
Location: Single located Gender: Not described
Setting: Nursing management rooms
with computers, hospital training room
Excluded: No further details

Tsai et al. (2004) Evaluation of computer-assisted Allocation: Random assignment Participants: First year novice nurses 1. Knowledge gain – Intravenous
multimedia instruction in intravenous Blindness: No N: 81 injection knowledge test
injection Design: Parallel Age: Mean age 23 2. Self-perceived intravenous
Location: Single located Gender: Female n = 78, Male n = 3 performance questionnaire Data not
Setting: In hospital facilities able to use
Excluded: No further details 3. Satisfaction questionnaire for e-
learning
M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149 143

contact teaching such as face-to-face lecturing and instruc- learning methods. However, the data from these three
tor led modules. The time for control group education varied studies were not usable due to lack of numerical data.
between 60 min and 360 min and it took slightly longer than
intervention group education (Table 2). 5. Discussion

4.5. Quantitative data synthesis This systematic review aimed to investigate the impact
of e-learning on knowledge, skills and satisfaction among
4.5.1. Impact of e-learning on knowledge level nurses and nursing students compared to traditional
Eleven studies reported the outcomes of e-learning or education methods. The preliminary evidence suggests
computer assisted learning on participants’ knowledge. that individualized, tailored e-learning approaches are
Eight studies (Beeckman et al., 2008; Bloomfield et al., more effective than traditional interventions (Lancaster
2010; Cega et al., 2007; Harrington and Walker, 2004; and Stead, 2005). This finding gave a promising lead in
Horiuchi et al., 2009; Hsiao Sheen et al., 2008; Paladino and health education and also guides the assumptions in our
Peres, 2007; Tsai et al., 2004) compared e-learning to study. Keeping in this finding in mind we found only 11
traditional learning. Four of these studies (Cega et al., 2007; studies out of 177 reporting effectiveness of e-learning on
Horiuchi et al., 2009; Paladino and Peres, 2007; Tsai et al., participants’ knowledge level. The finding is surprising,
2004) were usable for meta-analysis; three studies had to although e-learning is one of the fastest growing methods
be excluded from the quantitative meta-analysis because in the education industry (European Commission, 2010;
the data were unusable due to lack of numerical data Digital Agenda Assembly, 2011). As has been found in an
(Beeckman et al., 2008; Bloomfield et al., 2010; Harrington earlier review (e.g. Cook et al., 2008) most of the reports
and Walker, 2004). described comparisons with no intervention and had
Meta-analysis of studies comparing e-learning to therefore to be excluded from the analysis.
traditional learning (Cega et al., 2007; Horiuchi et al., The results of this review showed that e-learning is not a
2009; Paladino and Peres, 2007; Tsai et al., 2004) showed superior learning method to traditional learning methods.
slight impact on e-learning and heterogeneity I2 = 27%, Concerning our primary outcome, i.e. knowledge level, no
meaning that these interventions were suitable for meta- statistical differences between learning outcomes were
analysis. Although the random effect size showed some found. The finding is in line with previous reviews (Curran
improvement associated with e-learning compared to and Fleet, 2005; Wutoh et al., 2004), although more positive
traditional techniques, this was not statistically significant results can also be found in earlier reviews (e.g. Cook et al.,
(p = 0.39, MD 0.44, 95% CI 0.57 to 1.46) (Fig. 3). 2008). The reasons for this may for example have to do with
the method itself or the content of the education
4.5.2. Impact of e-learning on skills investigated in the studies included. In general, interactivity,
Four studies reported the outcomes of e-learning or practice exercises, repetition, and feedback improved
computer assisted learning on participants’ skills level learning outcomes (Cook et al., 2010a) and e-learning offers
(Beeckman et al., 2008; Bloomfield et al., 2010; Cega et al., a flexible method to include these elements in education.
2007; Hsiao Sheen et al., 2008). However, only one study However, we do not have detailed information on how those
(Cega et al., 2007) reported the data in a form suitable for elements were used in the interventions under investiga-
meta-analysis. It showed a slight impact on e-learning. tion. Furthermore, there is also a need to explore more
However, this was not statistically significant (p = 0.13, MD carefully possible content related limitations on the use of e-
0.03, 95% CI 0.09 to 0.69). Three studies (Beeckman et al., learning. In other words, whether e-learning is a more
2008; Bloomfield et al., 2010; Hsiao Sheen et al., 2008) relevant method to provide education on certain topics.
reported the data in such a way that it was not usable due We were also interested in whether e-learning is more
to a lack of numerical data. effective in improving learners’ skills than traditional
methods. Our analysis yielded no evidence for our
4.5.3. Impact of e-learning on satisfaction assumption, while no statistical differences between e-
Three studies (Horiuchi et al., 2009; Mcvey et al., 2009; learning and traditional learning methods to improve
Tsai et al., 2004) reported participant satisfaction with participant’s skills were found. To improve learners’ skills

e-Learning Traditional learning Mean Difference Mean Difference


Study or Subgroup Mean SD Total Mean SD Total Weight IV, Random, 95% CI IV, Random, 95% CI
Cega 2007 71 10 83 73 10 78 9.3% -2.00 [-5.09, 1.09]
Horiuchi 2009 76.2 18.8 37 79.4 21.5 33 1.1% -3.20 [-12.71, 6.31]
Paladino 2007 1.7 2.8 24 1.3 3.8 25 20.9% 0.40 [-1.46, 2.26]
Tsai 2004 9.67 0.53 42 8.82 0.6 39 68.6% 0.85 [0.60, 1.10]

Total (95% CI) 186 175 100.0% 0.44 [-0.57, 1.46]


Heterogeneity: Tau² = 0.37; Chi² = 4.14, df = 3 (P = 0.25); I² = 27%
-4 -2 0 2 4
Test for overall effect: Z = 0.86 (P = 0.39)
Favours traditional learn Favours e-learning

Fig. 3. Forest plot of e-learning vs. traditional learning.


144
Table 2
Description of intervention and control learning methods.

Authors Method Description of intervention Time of Method Description of control Time of control
intervention

Beeckman et al. (2008) e-Learning Name: The Pressure Ulcer 60 min Lecture Name: Lecture related to 60 min
Classification (PUCLAS) pressure ulcers classification
Topic: Programme provides Topic: Lecture provides same
information about pressure content than e-Learning
ulcers and its classification programme
Phases: Exercises on different Phases: –
levels of difficulty Methods: Lecture using
Methods: Text, photographs PowerPoint
and video Time: 1 h

M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149


Time: 1 h Self-standing: –
Self-standing: Yes

Bloomfield et al. (2010) Computer programme Name: – 90 min Lecture Name: – 90 min
Topic: Programme related hand Topic: Lecture related hand
washing technique washing technique
Phases: Six steps for right hand Phases: Lecture and practice
washing Methods: Lecture, slides, video,
Methods: Text, interactive additional material and
activities: animated practice session
multimedia, photographs, Time: 90 min
video and links to website Self-standing: –
Time: 90 min
Self-standing: Yes

Cega et al. (2007) Compuer programme Name: ‘‘FearFighter’’ 60 min Lecture Name: – 60 min
Topic: Programme explains Topic: Experienced lecturer
how exposure therapy works gave a powerpoint presentation
with phobia/panic covering content like
Phases: 9 steps ‘‘FearFighter’’
Methods: – Phases: Lecture
Time: Each step takes 5–20 min Methods: Lecture using
Self-standing: Yes PowerPoints, discussion and
answering questions
Time: 60 min
Self-standing: –

Harrington and Walker (2004) Computer program Name: ‘‘Fire Safety in Nursing NA Instructor led Name: – NA
Facilities’’ modules Topic: Includes material related
Topic: Programme includes fire safety in nursing facilities
material related fire safety in Phases: 6 modules
nursing facilities Methods: Instructor led
Phases: 6 modules modules
Methods: Storyboard, videos, Time: One module, 34–43 min
questions, games, text and Self-standing: –
animation.
Time: One module, 26–41 min
Self-standing: Yes
Harrington and Walker (2006) Computer programme Name: ‘‘Ergonomics for Nursing NA – No training NA
Facility Mangers’’
Topics: Programme includes
information related to
ergonomics. Six main topics.
Phases: Programme have 54
separate screen and 44 photos
and also interactive exercises.
Methods: Text, graphics,
photographs, animation,
sounds, interactive questioning
and answering.
Time: NA
Self-standing: Yes

M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149


Horiuchi et al. (2009) e-Learning Name: ‘‘Evidence-Based 120 min, in 1 Lecture Name: – 360 min in 1 month period
Nursing’’ month period Topics: 4 lectures related to
Topics: Programme includes EBN
information related to EBN Phases: 4 parts
Phases: 4 parts Methods: Face-to-face lecture
Methods: NA Time: Each part took 90 min.
Time: Each part took 30 min. Programme completed in 1
Programme completed in 1 month.
month. Self-standing: –
Self-standing: Yes

Hsiao Sheen et al. (2008) e-Learning Name: ‘‘ELEP’’ 330 min, in a 3 Lecture Name: ‘‘TICP’’ 330 min, in a 3 month
Topics: Programme included month period. Topics: Lectures included case period
case study, career study, career development,
development, teaching and teaching and learning, nursing
learning, nursing and law and and law and communication
communication Phases: 5 lectures
Phases: 5 phases Methods: Presentations
Methods: Audio, video and Time: 330 min
PowerPoints. Self-standing: –
Time: 330 min
Self-standing: Yes

Irvine et al. (2008) e-Learning Name: ‘‘Professional dementia NA – No training NA


care: Managing Aggression’’
Topics: Programme included
information related to
approaching agitated resident
and safety de-escalating
techniques.
Phases: NA
Methods: Written text,
graphics, images, testimonials,
videos and voice over clips
Time: NA
Self-standing: Yes

145
146
Table 2 (Continued )

Authors Method Description of intervention Time of Method Description of control Time of control
intervention

Mcvey et al. (2009) e-Learning Name: ‘‘The Student Body: 60 Days access to – No training NA
Promoting Health at Any Size’’ online programme
Topics: Programme included
information related to health at

M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149


any size
Phases: Programme includes
six modules and each module
consist four steps
Methods: Written text,
animation, videos and links
Time: NA
Self-standing: Yes

Paladino and Peres (2007) e-Learning Name: ‘‘Quality tools’’ 40 min Lecture Name: – 120 min
Topics: Programme included Topics: Programme included
information related to hospital information related to hospital
quality quality
Phases: NA Phases: NA
Methods: Programme used Methods: Lecture used
powerpoint presentations powerpoint presentations
Time: 40 min Time: 120 min
Self-standing: Yes Self-standing: –

Tsai et al. (2004) Computer programme Name: ‘‘Intravenous injection’’ 90 min Lecture Name: – NA
Topics: Programme included Topics: Orientation lecture
information related to included information related to
intravenous injection and its intravenous injection and its
administration administration
Phases: Three 30 min sessions Phases: –
Methods: Programme Methods: Lecture
delivered via CD-ROM, Time: NA
programme using text, voice, Self-standing: –
film and pictures
Time: 120 min
Self-standing: Yes
M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149 147

there is a need to integrate the content of the education important to understand that assessing knowledge can
into clinical nursing practice (Morgan, 2006). On the other take many forms with a number of different conceptual
hand, e-learning methods are still fairly new in this field definitions. Therefore, one might question whether the
and this aspect may not be considered in existing data can be combined without manipulation, especially
educational interventions. Therefore it may be that when all the studies included used self-developed instru-
existing educational interventions cannot adequately ments. Moreover, overall results are much influenced by
respond to participants’ needs and experiences in clinical the Tsai et al. (2004) study due to its small standard
practice. Thus, to improve participants’ skills by using e- deviation. However, we considered the scales similar
learning this integration should be taken into account in enough to be combined in the analysis. The same approach
the development of e-learning interventions (Murdoch was used in a systematic review by Cook et al. (2008). Due
et al., 2012). to these limitations there is a risk of overestimating the
Lastly, we assumed that e-learning has a positive effects of the experimental interventions. Therefore there
impact on learners’ satisfaction with education. However, is still a need for further studies to assess the impacts of e-
from our data it was not possible to find answers to our learning in nursing education.
question due to missing statistical information. Earlier
studies (e.g. Wutoh et al., 2004) have reported participants’ 5.2. Implications for practice
satisfaction related to educational methods showing better
outcome for e-learning. In our review of qualitative Our review can inform educational policymakers and
analysis on satisfaction Tsai et al. (2004) showed that healthcare commissioners in deciding whether e-learning
students are more satisfied with e-learning. Also, Mcvey should be part of the nursing curriculum in basic education
et al. (2009) showed similar effects on satisfaction in their or on-the-job training in nursing education. According to
study on the use of e-learning (also Cook et al., 2008; our analysis none of the learning methods used, neither e-
Curran and Fleet, 2005). Whether this is true or not, more learning nor more traditional learning methods are
high quality RCT studies should be conducted. superior to increase students’ knowledge level, skills, or
satisfaction with the learning methods. However, the
5.1. Strengths and limitations of the review knowledge base is not strong due to the lack of high quality
research. It is therefore important to be aware that
This review has both strengths and limitation. First, the different educational methods including e-learning are
strengths of this review include a systematic approach to available as means of educating nurses and nursing
searching, screening and reviewing studies and extracting students.
data using standardized forms and duplicating all stages. Based on the results of this review we can agree with
Second, the search area was also large and the inclusion Cook et al. (2010a,b) who concluded in their review the
criteria broad enough to encompass the broadest range of educators and researchers cannot treat web-based learn-
interactive e-learning interventions. ing methods as a single entity. Educators should carefully
The review also has some limitations. Although every consider the needs of their learners and the learning
effort was made to locate published trials our findings may context in question when deciding whether to use this
still include selective reporting. The study also involves medium, other media or a combination. Those electing to
judgments made by the review authors, either of which use e-learning should consider a broad range of methods
may lead to bias. Also, the outcome data was sparsely before choosing a specific approach. Instead of concluding
reported and due to this we found that a large number of whether e-learning methods are good or bad based on the
the papers included did not report any numerical data. This authors’ best understanding, these methods should be
may cast doubt on the validity of the inclusion procedures. used with full awareness of participant groups and their
All studies included in this review were randomized. needs.
However, the details were not frequently provided. It is
therefore unclear in almost all studies whether randomi- 5.3. Implications for research
zation was really appropriately done. The interventions
were also rather heterogeneous which might raise the This review showed clearly the need to need to conduct
question about the meaningful use of the meta-analysis. studies in the field of e-learning. The evaluation of
However, all interventions used e-learning as a interven- educational interventions should focus on a variety of
tion and therefore the meta-analysis was considered useful outcomes as noted in Kirkpatrick’s model of learning
and suitable method (Higgins and Green, 2011). In outcome evaluation (Galloway, 2005). Future studies
addition, the research papers in this review used rather should use adequate power calculations to be properly
small samples and adequate power calculations to weight. Also, the randomization process should be
estimate sample sizes were not presented in the papers. conducted and reported in greater detail so that sufficient
Only two studies (Cega et al., 2007; Paladino and Peres, validity assessment is possible. Moreover, researchers
2007) showed that their studies were powered. need to pay attention to the reporting the numerical data.
Moreover we found considerable limitations regarding In general, the importance of the CONSORT and QUOROM
the tools for measuring study outcomes. In general they statements should be taken more seriously into account in
were only briefly described in the studies, so no appraisal future studies. Following these recommendations would
of measurement tools can be presented in this review. clearly improve the conduct and reporting of empirical
Especially regarding the measurements of knowledge it is research on certain topic following a methodological
148 M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149

protocol such as randomized controlled trials. These Commission of the European Communities, 2000. e-Learning – Designing
tomorrow’s education. Communication from the Commission. Brus-
recommendations would also facilitate critical appraisal. sels, 24.5.2000. COM (2000) 318 final.
The QUOROM statement and flow chart of the review aim Commission of the European Communities, 2003. e-Learning – Designing
to produce better quality reviews and provide evidence- tomorrow’s education. Commission staff working paper eLearning:
designing tomorrow’s Education A Mid-Term Report As requested by
based knowledge for practitioners (Turpin, 2005). the Council Resolution of 13 July 2001. Brussels, 30.7.2003 SEC (2003)
905.
6. Conclusion Cobb, S., 2004. Internet continuing education for health care profes-
sionals: an integrative review. The Journal of Continuing Education
in the Health Professionals 24, 171–180.
This systematic review of the impact of e-learning Curran, V., Fleet, L., 2005. A review of evaluation outcomes of web-based
compared to traditional education in the acquisition of continuing medical education. Medical Education 39, 561–567.
Curran, V., Fleet, L., Kirby, F., 2010. A comparative evaluation of the effect
knowledge, skills and satisfaction among nurses and
of internet-based CME delivery format on satisfaction, knowledge and
student nurses’ showed that there is no difference between confidence. Medical Education 10 (10), 1–7.
e-learning or traditional learning. Even the e-learning is Digital Agenda Assembly, 2011. Report from the workshop 08. ‘‘Main-
not superior to traditional learning it can, however, offer an streaming e-Learning in education and training’’ DAE action 6. Brus-
sels, 16–17.7.2011.
alternative method of education. In general, this review Egger, M., Davey-Smith, G., Schneider, M., Minder, C., 1997. Bias in meta-
offers important information to increase knowledge base analysis detected by a simple graphical test. BMJ 315, 629–634.
about effectiveness of different education methods. This European Commission, 2010. Communication from the Commission Eur-
ope 2020. A strategy for smart, sustainable and inclusive growth.
information can be used to support decision makers to Brussels, 3.3.2010. COM (2010) 2020 final.
choose those methods which have impacts on students’ European Commission, 2011. Communication from the Commission to
satisfaction and knowledge level as well support change in the European parliament, the Council, the European Economic and
social committee and committee of the regions. Supporting growth
practice. In future there is still need to develop and and jobs – an agenda for the modernisation of Europe’s higher
evaluate methods for education among nurses. It is education systems. Brussels, 20.9.2011. COM (2011) 567 final.
important that these studies are conducted to show Eurostat, 2011. Healthcare staff statistics at regional level – Statistics
Explained (2011/11/0), http://epp.eurostat.ec.europa.eu/statistic-
effectiveness and they should also focus on the variety
s_explained/index.php/Healthcare_staff_statistics_at_regional_level.
of different levels of outcomes. Galloway, D., 2005. Evaluating distance delivery and e-learning. Perfor-
mance Improvement 44 (4), 21–27.
Conflict of interest: None declared. Guyatt, G.H., Oxman, A.D., Vist, G., Kunz, R., Brozek, J., Alonso-Coello, P.,
Montori, V., Akl, E.A., Djulbegovic, B., Falck-Ytter, Y., Norris, S.L.,
Williams Jr., J.W., Atkins, D., Meerpohl, J., Schünemann, H.J., 2011.
Funding: Funding received for this study from Turku Uni- GRADE guidelines. 4. Rating the quality of evidence – study limita-
tions (risk of bias). Journal of Clinical Epidemiology 64 (4), 407–415.
versity Foundation and The Finnish Association of Nursing Harrington, S., Walker, B., 2004. The effects of computer-based training on
Research. Funders did not have any role in the study. immediate and residual learning of nursing facility staff. The Journal
of Continuing Education in Nursing 35 (4), 154–163.
Harrington, S., Walker, B., 2006. Teaching ergonomics to Nursing facility
managers using computer-based instruction. Journal for Nurses in
Ethical approval: No ethical permission was needed.
Staff Development 22 (5), 260–268.
Higgins, J.P.T., Green, S. (Eds.), 2011. Cochrane Handbook for Systematic
References Reviews of Interventions Version 5.1.0. The Cochrane Collaboration
Available at: www.cochrane-handbook.org (retrieved 24.1.2013).
Ades, A., Higgins, J., 2005. The interpretation of random-effects meta- Higgins, J., Thompson, S., 2002. Quantifying heterogeneity in meta-ana-
analysis in decision models. Medical Decision Making 25, 646–654. lysis. Statistics in Medicine 21, 1539–1558.
Beeckman, D., Scoonhoven, L., Boucque, H., Van Maele, G., Defloor, T., Higgins, J., Thompson, S., Deeks, J., Altman, D., 2003. Measuring incon-
2008. Pressure ulcers – e-learning to improve classification by nurses sistency in meta-analyses. British Medical Journal 327, 557–560.
and nursing students. Journal of Clinical Nursing 17, 1697–1707. Horiuchi, S., Yaju, Y., Koyo, M., Sakyo, Y., Nakayama, K., 2009. Evaluating of
Bloomfield, J., Roberts, J., While, A., 2010. The effects of computer assisted a web-based graduate continuing nursing education program in
learning versus conventional methods on the acquisition and reten- Japan: a randomized controlled trial. Nurse Education Today 29,
tion of handwashing theory and skills in pre-qualification nursing 140–149.
students: a randomized controlled trial. International Journal of Hsiao Sheen, S.-T., Chang, W.-Y., Chen, H.-L., Chao, H.-L., Tseng, C., 2008. E-
Nursing Studies 47, 287–294. learning education programme for registered nurses: the experience
Belcher, J., Vonderhaar, K., 2005. Web-delivered research-based staff of a teaching medical center. Journal of Nursing Research 16 (3), 195–
education for seeking magnet status. Journal of Nursing Administra- 200.
tion 35 (9), 382–386. Irvine, B., Bourgeois, M., Billow, M., Seeley, J., 2007. Internet training for
Cega, L., Norman, I., Marks, I., 2007. Computer-aided vs. tutorial-delivered nurse aides to prevent resident aggression. Journal of the American
teahing of exposure therapy for phobia/panic: randomized controlled Medical Directors Association 8 (8), 519–552.
trial with pre-registration nursing students. International Journal of Khan, K., Kunz, R., Kleijnen, J., Antes, G., 2003. Systematic Reviews to
Nursing Studies 44, 397–405. Support Evidence-Based Medicine. How to Review and Apply findings
Cohn, L.D., Becker, B.J., 2003. How metaanalysis increases statistical of Health Care Research. RSM Press, London.
power. Psychological Methods 8, 243–253. Kirkpatrick, D., 1998. Evaluating Training Programs. The Four Levels.
Cook, D., Levinson, A., Garside, S., 2008. Internet-based learning in the Berrett-Koehler Publishers, San Francisco.
health professions. Journal of American Medical Association 30 (10), Lancaster, T., Stead, L., 2005. Self-help interventions for smoking cessa-
1181–1196. tion. Cochrane Database of Systematic Reviews (3), http://dx.doi.org/
Cook, D., Levinson, A., Garside, S., 2010a. Instructional design variations in 10.1002/14651858.CD001118.pub2 Art. No.: CD001118.
internet-based learning for health profession education: a systematic Leucht, S., Engel, R.R., Bauml, J., Davis, J., 2007. Is the superior efficacy of
review and meta-analysis. Academic Medicine 85 (5), 909–922. new generation antipschotics an artifact of LOCCF? Schizophrenia
Cook, D., Garside, S., Levinson, A., Dupras, D., Montori, V., 2010b. What do Bulletin 33 (1), 183–191.
we mean by web-based learning? A systematic review of the varia- Lowry, M., Johnson, M., 1999. Computer assisted learning: the potential
bility of interventions. Medical Education 44, 765–774. for teaching and assessing in nursing. Nurse Education Today 19,
Commission of the European Communities, 2001. Communication from 521–526.
the Commission to the Council and the European Parliament. The Mcvey, G., Gusella, J., Tweed, S., Ferrari, M., 2009. A controlled evaluation
eLearning Action Plan. Designing tomorrow’s education. Brussels, of web-based training for teachers and public health practitioners on
28.3.2001. COM (2001)172 final. prevention of eating disorders. Eating Disorders 17, 1–26.
M. Lahti et al. / International Journal of Nursing Studies 51 (2014) 136–149 149

Moher, D., Liberati, A., Tetzlaff, J., Altman, D., The PRISMA Group, 2009. Schittek, M., Mattheos, N., Lyon, H., Attström, R., 2001. Computer assisted
Preferred reporting items for systematic reviews and meta-analyses: learning. A review. European Journal of Dental Education 5, 93–100.
the PRISMA statement. PLoS Medicine 6 (6), e1000097 http:// Simpson, B., 2003. Web-based and computer-assisted instruction in physical
dx.doi.org/10.1371/journal.pmed1000097 (retrieved 24.1.2013). therapy education. Journal of Physical Therapy Education 17, 45–49.
Morgan, R., 2006. Using clinical skills laboratories to promote theory- Smith, C., 2005. E-orientation: a cyber approach to orienting per diem and
practice integration during first practice placement: an Irish perspec- temporary nurses. Journal for Nurses in Staff Development 21 (5),
tive. Journal of Clinical Nursing 15 (2), 155–161. 204–212.
Moore, D., McCabe, G., 2003. Introduction to the Practice of Statistics, 4th Tsai, S.-L., Tsai, W.-W., Chai, S.-K., Sung, W.-H., Doong, J.-L., Fung, C.-P.,
ed. W.H. Freeman & Company. 2004. Evaluation of computer assisted multimedia instruction in
Murdoch, D., Bushell, C., Johnson, S., 2012. Designing simulations for intravenous injection. International Journal of Nursing Studies 41,
professional skill development in distance education: a holistic 191–198.
approach for blended learning. In: Holt, D., Segrave, S., Cybulski, J. Turpin, D., 2005. CONSORT and QUOROM guidelines for reporting ran-
(Eds.), Professional Education Using E-Simulations: Benefits of Blended domised clinical trials and systematic reviews. American Journal of
Learning Design. IGI Global, (10 January 2012), pp. 121–140. Orthodontics and Dentofacial Orthopedics 128 (6), 681–685.
Paladino, Y., Peres, H., 2007. E-learning: a comparative study for knowl- University of York, 2008. Systematic Reviews: CRD’s Guidance for Under-
edge apprehension among nurses. The Revista Latino-Americana de taking Reviews in Health Care. University of York, Centre for Reviews
Enfermagem 15 (3), 397–403. and DisseminationIn: http://www.york.ac.uk/inst/crd/pdf/Systema-
Ray, J., Shadish, W., 1996. How interchangeable are different estimators of tic_Reviews.pdf (retrieved 9.1.2012).
effect size? Journal of Consulting and Clinical Psychology 64 (6), Ward, R., Stevens, C., Brentnall, P., Briddon, J., 2008. The attitudes of health
1316–1325. care staff to information technology: a comprehensive review of the
Savoie, I., Helmer, D., Green, C., Kazanjian, A., 2003. Beyond Medline: literature. Health Information and Libraries Journal 25, 81–97.
reducing bias through extended systematic review search. Interna- Wutoh, R., Boren, S., Balas, A., 2004. eLearning: a review of internet-based
tional Journal of Technology Assessment in Health Care 19 (1), continuing medica education. The Journal of Continuing Education in
168–178. the Health Professions 24, 20–30.

You might also like