Nama : Siti Maisaroh

NIM :20170310158
Tutorial : 6

Tugas PICO

Judul Jurnal : A randomised double blind trial to compare the efficacy and tolerability of

itopride hydrochloride versus domperidone in patients with non- ulcer dyspepsia: bloating

predominant type.

Penulis : Gopesh Valoth, Sabeena Kizhedath

Tahun Terbit : 2017

P I C O
The efficacy and Patients with 50mg Patients with 10mg Both the drugs
safety of Itopride of Itopride three of Domperidone significantly
and Domperidone in three times daily.
times daily. produced
bloating
predominant non symptomatic relief.
ulcer dyspepsia Though
patients. Domperidone is
marginally
beneficial
compared to
Itopride after 4
weeks treatment in
terms of
improvement in
symptom scores,
the Subjective
Global Assessment
of relief did not
show any
significant
improvement
between the two
drugs.