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= ltSele Dae Syndrom,
* Down Syadrom 2 Known as alrisemy a;
3 is
a genetic lis orccer Caused by presence cf al or put
oF a third copy oF chromesome dl. Tt5 typically ameinhe
With physical quwt elays ; Characteristic Facial
Pemtitves , cele mill to moermte intellectual os ability.
The incidence in. lite ~ bern. infints Is about =p[t
* Types of Doun Synctom e-
fer otis Junction CHE AD = FRR CE) Chasnames.
a Trans location CL-3 %) _ Perk of Ci") chrmosemes
brecKs clown Goff} and attaches fo another chyomeremes,
3- Mo saicism C2%) _ Up even balance of chiemorones
Ma cells C46 ve. YF)-
Pil ikea ow tapes.
@ Typicel cranio facial appearance »
— Round Pace ancl fat Nasal brielge anal Up slanted palpebral tien
— Brush. field spots in iris 7, anol Small Mouth and Prot riding.
bengue
= Smell ears, Epicanthic flats ; That occiput ond fantanelle.
@ Obie stninn ling
—lthorE WEEK, single palmar create, atl incuves HiPth fiqe
= Hypo tenia ; ane congenital heart Lefeets CYen%)
— Duc dent atresia.
-Velatively late Levelopment of seciclucus and Pema
teeth as “Compared with the chileen ,
= Teeth could apper in ach fferent Seyuence and positions.
- Teeth ave often youncled, fever teeth, and Maxilla is nen
- The Zonque appears tx big for the month.
- Habit of ‘breathing thyow the mouth,# Cadsese
Q The cause of extra tell or por tiad chrems some is stil
Un Known .
@ Aaternel age is the only factor that has been
linKeeé te en fncvenseeC chance of having a baby with
Des: ye sulting trom Non — Lis junction o¥ Mosaicisnr,
Bop of chiletren with DS, ate. hyn te women
under (35) yrs of age
@ 5%. ef He cases have been traces’ é the Ather,
. Dies ghesing Dewn. Syneteem e
oO 5 crecning cleaving Pregremeys-
(cold) es [BLE (pucchel Banco sind
betreen [IN ant [H) weeks of pregnancy,
Q Diag resis cleving preg pamey t S
FEV S|—e usutly Lone fom week (P of fteghancy
[Amniocentesis 0 Wally Cupiet out from weels (6) of pregnaney
» Masagement s-
There. ave ne meclicn| treatments fy intellectual
Ais atiltty associated with Down Synclrem, but imeroved
Mediat cave has greatly chhanece’ gpten lity of life amet
“Incveatad lite expectancy.
plies ae
(65)) eo) eee