PENGGUNAAN OBAT PADA

PASIEN HAMIL DAN MENYUSUI

(CQ DAN HCQ)
KELOMPOK 8 – KELAS A:

EVA WIDYASARI (2020404476)

FAISAL NUR ARIB (2020404477)
FATIKA SURYANDARI (2020404478)
FAUZAH LAMH WAHIDAH (2020404479)
LITERATUR TERSIER
1. IS THE JOURNAL CONSIDERED REPUTABLE? IS THE JOURNAL APPROPRIATE TO
FIND AN ARTICLE RELATING TO THIS PARTICULAR SUBJECT? THE LANCET
INFECTIOUS DISEASE IS APPROPRIATE TO FIND ABOUT INFECTIOUS DISEASE AND
OTHER RELATED PROBLEMS.
2. DO THE RESEARCHERS APPEAR TO HAVE THE APPROPRIATE QUALIFICATIONS
FOR UNDERTAKING THE STUDY? WAS THE RESEARCH PERFORMED IN AN
APPROPRIATE MEDICAL FACILITY? YES, THEY ARE FORM REPUTABLE MEDICINAL
UNIVERSITY.
3. WHAT WAS THE SOURCE OF FINANCIAL SUPPORT FOR THE STUDY? U.S.
NATIONAL INSTITUTE OF HEALTH.
 4. DO THE AUTHORS GIVE SUFFICIENT BACKGROUND INFORMATION FOR THE
STUDY? DID THEY DEMONSTRATE THAT THE STUDY WAS IMPORTANT AND
ETHICAL? YES, THEY WROTE IN BACKGROUND THAT MALARIA DURING PREGNANCY
CAN HAVE SIGNIFICANTLY IMPACT THE HEALTH OF PREGNANT WOMEN, AND THEIR
NEWBORNS.
5. Are the purpose and the objectives clearly stated and free from bias? The
purpose of the study is objectives clearly state and free from bias,
6. WAS THE STUDY APPROVED BY AN INVESTIGATIONAL REVIEW BOARD?
7. DOES THE INVESTIGATOR STATE THE NULL HYPOTHESIS? IS THE ALTERNATIVE
HYPOTHESIS STATED?
8. IS THE SAMPLE SIZE LARGE ENOUGH? IS THE SAMPLE REPRESENTATIVE OF THE
POPULATION? YES, THE SAMPLE SIZA IS 1209 WOMEN.
 10. WAS THE STUDY RANDOMIZED CORRECTLY? EVEN IF THE STUDY IS
ADEQUATELY RANDOMIZED, ARE THE GROUPS (TREATMENT AND CONTROL)
EQUIVALENT? YES.
11. What is the study design? Is it appropriate? Yes, it is appropriate. The
study design is Randomized Controlled Clinical Trial.
12. WAS THE STUDY ADEQUATELY CONTROLLED? WERE THE CONTROLS ADEQUATE
AND APPROPRIATE?
 13. WAS THE STUDY
ADEQUATELY BLINDED?
14. WERE APPROPRIATE DOSES AND REGIMENS USED FOR THE DISEASE STATE
UNDER STUDY? YES.
18. Were appropriate statistical tests chosen to assess the data?
27. ARE ADVERSE REACTIONS
REPORTED IN SUFFICIENT
DETAIL?
28. ARE THE CONCLUSIONS SUPPORTED BY THE DATA? IS SOME FACTOR OTHER
THAN THE STUDY TREATMENT RESPONSIBLE FOR THE OUTCOMES? YES.
29. ARE THE RESULTS BOTH STATISTICALLY AND
CLINICALLY SIGNIFICANT?
30. DO THE AUTHORS DISCUSS
STUDY LIMITATIONS IN THEIR
CONCLUSIONS?
31. WERE APPROPRIATE REFERENCES USED? ARE REFERENCES TIMELY AND
REPUTABLE? HAVE ANY OF THE STUDIES BEEN DISPROVEN OR UPDATED? DO
REFERENCES CITED REPRESENT A COMPLETE BACKGROUND? YES, THE
REFERENCES ARE FROM REPUTABLE JOURNAL AND AUTHORS.