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Infertility and Mental Health
Infertility and Mental Health
P. Tracy Crudup-Arata
November 9, 2020
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The journey that an individual embarks upon when suffering from infertility can greatly
impact their life medically, financially, and personally. The struggle to conceive a child and the
impact it imparts on women is multi-faceted. Infertility affects females of child-bearing age and
current statistics illustrates that 48 million couples suffer from infertility whether it is primary or
secondary infertility (World Health Organization, 2020). Primary infertility is diagnosed when
no other biological children have resulted and secondary infertility is a minimum of one
Patients undergoing infertility treatment have a higher risk of being diagnosed with post-
traumatic stress disorder, depression, and anxiety (Rooney & Domar, 2018). The level of stress
will vary from woman to woman, based upon the mental and physical health of the individual.
There are many steps to the infertility process that women must navigate. This includes multiple
medical procedures, possible time away from their profession in order to recover, managing the
physiological and psychological changes, including disappointment and grief. Each experience is
personal and each must learn to effectively manage their expectations and their reality. As
clinicians become increasingly knowledgeable about the mental health effects of the infertility
journey, they are better able to evaluate, plan, and implement the most appropriate treatment and
care.
technology (ART) that women utilize to conceive. The procedure is costly, usually takes
multiple attempts, usually not covered by insurance, and offers no guarantees. According to the
Center for Disease Control and Prevention, approximately 1.7% of United States births are the
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result of utilizing ART (Center for Disease Control and Prevention [CDC], 2019). The mental
health status of a woman choosing in-vitro fertilization is vital. The individual needs to be
assessed in a variety of areas in order to determine the psychological stability that is needed to
undergo the fertility treatment (Lawson, Klock, Pavone, Hirshfeld-Cytron, Smith & Kazer,
2015). The Center for Disease Control and Prevention 2017 Fertility Clinic Success Rates Report
illustrated that 284,385 ART procedures were performed in United States in 2017. There are 448
fertility clinics that report their statistics to the CDC each year. Of the 284,385 ART procedures,
there were 68,908 live births in 2017 (Center for Disease and Prevention, 2020).
Trends
Infertility patients are in crisis (Peterson et al., 2012). The risk factors for stress during
infertility treatment can escalate due to several factors including accepting the state of being
childless, managing the depression, coping, and understanding the possible relationship
sacrifices that may present during the process (Wischmann et al., 2009). Based on CDC’s 2018
Fertility Clinic Success Rates Report, there were 306,197 ART procedures 456 reporting clinics.
This is eight additional clinics that have opened in one year to meet the demand for infertility
treatment. This demand increased the resulting births in 2018 to 73,831 (Center for Disease and
Prevention, 2020). This is an increase of 4,923 births which increases the number of women that
will possibly suffer from mental health effects from the stress of infertility.
The Center for Disease Control reports that women aged 15-49 with impaired fecundity
is 13.1%, with subgroups of married women aged 15-49 with impaired fecundity being 16.2%.
Married women in the same age range that are infertile are reported as 8.8% while only 12.7%
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utilize fertility treatments (Center for Disease Control and Prevention [CDC], 2020). One study
suggested that 56.5% of women in their research scored in the clinical significant range for
depression on multiple assessments and 75.9% of women scored in the clinically significant
range for anxiety. Symptoms for each were higher for women who remained infertile without
ever conceiving than those achieving a live birth (Pasch et al., 2016). It is reported that
Importance
The importance of studying this area of mental health is vital due to the enormous gaps in
literature, previous findings, current studies and the rising number of infertility cases each year.
Some studies point to increased stress and mental health effects but some studies are completed
early in pregnancy and may not take into account the journey to conceive or the stress or rate of
miscarriage. One study conducted in the United States, illustrated that infertility patients utilizing
in-vitro fertilization procedures had lower level of depressive symptoms than the general
population undergoing pregnancy-related procedures (Lewis, Liu, Stuart & Ryan, 2013).
A different study suggests infertile women were less likely to suffer from post-partum
depression after achieved live birth than other women (Raguz, McDonald, Metcalfe, O’Quinn, &
Tough, 2014). One association between stress and infertility has been linked to the personal view
of motherhood and how infertility patients view giving birth as being representative of defining
With the rising number of ART procedures annually, there are other factors to consider
such as deciding what to do with existing embryos that may not be utilized. Some opt to have
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these embryos adopted by other infertile couples and they agree to terminate their rights to the
embryo (Frith & Blyth, 2013). This can cause further distress for the patient. Understanding how
stress impacts the fertility is of vital importance. A study of salivary α-amylase levels which is a
biomarker for stress was conducted on 501 participating women in the United States. The results
indicated that females in the top 25% for clinically significant level were twice as likely to suffer
from infertility (Rooney & Domar, 2018). Being able to manage the level of stress before during
and after pregnancy plays an importance key role in the success of conception and pregnancy.
many patients over the years ranging from initial infertility diagnosis to termination of their
infertility treatment. Initial diagnosis usually presents as disbelief and self-doubt and termination
of infertility journey can range from lack of success with their journey to eventually delivering a
healthy baby. The range of mental health stress is varied and may affect several vital areas of
their life. Some struggle to afford the repeated treatments that may be necessary and some
The range of distress must be diagnostically assessed, a plan of treatment established, and
then implemented. Every woman undergoing infertility treatment has different goals, different
resources, and different perspectives about family. Every patient undergoing infertility treatment
has to be able to explore the risks associated with the medical procedures, the emotional stress,
social and moral dilemmas as well as the personal risks to self and family. Providers must be
able to implement their expertise by having a thorough understanding of the mental health
impact of infertility.
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Resource Sheet
financial impact, psychological and physiological trauma including PTSD and grief
Females experience greater mental health issues as a result of infertility than men.
infertility.
2. Academic Resources:
ISBN-13: 978-0521619493
b. The Boston IVF Handbook of Infertility: A Practical Guide for Practitioners Who
Care for Infertile Couples, 4th Edition (Reproductive Medicine and Assisted
ISBN-13: 978-1138633025
c. The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma by
ISBN-13: 978-0143127741
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d. Walking through Infertility: Biblical, Theological, and Moral Counsel for Those Who
ISBN-13: 978-1433559310
j. https://www.healthline.com/health/best-books-infertility#Unsung-Lullabies
thewholesomelotusfertility.com.+ Follow
h. https://www.healthline.com/health/best-infertility-blogs#4
i. https://www.mysurrogatemom.com/top-ten-infertility-blogs/
a. https://www.asrm.org/resources/patient-resources/
b. https://www.reproductivefacts.org/resources/educational-
videos/?_ga=2.112068876.928399747.1604276703-62133600.1604276703
c. https://www.reproductivefacts.org/resources/state-infertility-insurance-laws/
d. https://resolve.org/
e. https://www.reproductivefacts.org/faqs/faqs-about-the-psychological-component-of-
infertility/
f. https://www.fertilitymemphis.com/
g. https://psychologytoday.com
h. https://www.ihr.com/infertility/
i. https://www.sartcorsonline.com/rptCSR_PublicMultYear.aspx?ClinicPKID=2000
j. https://agcscholarships.org/about-agc/
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References
Center for Disease Control and Prevention (2019). Assisted reproductive technologies.
https://www.cdc.gov/art/artdata/index.html
https://www.cdc.gov/art/artdata/index.html
https://www.cdc.gov/nchs/fastats/infertility.htm
Frith, L., & Blyth, E. (2013). They can’t have my embryo: the ethics of conditional embryo
Lawson, A., Klock, S., Pavone, M., Hirshfeld-Cytron, J., Smith, K., & Kazer, R. (2015).
http://dx.doi.org/10.1080/07347332.2015.1045677
Lewis, A., Liu, D., Stuart, S., & Ryan, G. (2013). Less depressed or less forthcoming? Self-
Neter, E., & Goren, S. (2017). Infertility centrality in the woman’s identity and goal adjustment
http://dx.doi.org/10.1007/s12529-017-9693-9
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Pasch, L., Holley, S., Bleil, M., Shehab, D., Katz, P. & Alder, N. (2016). Addressing the needs of
fertility treatment patients and their partners: are they informed of and do they receive
https://doi.org/10.1016/j.fertnstert.2016.03.006
Peterson, B., Boivin, J., Norré, J., Smith, C., Thorn, P., & Wischmann, T. (2012). An
introduction to infertility counseling: a guide for mental health and medical professionals.
https://doi.org/10.1007/s10815-011-9701-y
Raguz, N., McDonald, S., Metcalfe, A., O’Quinn, C., & Tough, S. (2014). Mental health
outcomes of mothers who conceived using fertility treatment. Reproductive Health 11(1).
http://doi:10.1186/1742-4755-11-19
Rooney, K., & Domar, A. (2018). The relationship between stress and infertility. Dialogues in
https://doi.org/10.31887/DCNS.2018.20.1/klrooney
Wischmann, T., Scherg, H., Strowitzki, T., & Verres, R. (2009). Psychosocial characteristics of
women and men attending infertility counselling. Human Reproduction, 24(2), 378–385.
https://doi.org/10.1093/humrep/den401
sheets/detail/infertility