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    Anticoagulants, ACE Inhibitors

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    Gwyneth Cartalla
    This document summarizes potential drug-drug and drug-food interactions for several common anticoagulant and ACE inhibitor medications. It notes that certain drugs may decrease the metabolism or clearance of anticoagulants like apixaban and dabigatran, increasing their anticoagulant effects and bleeding risk. Foods and supplements containing compounds with anticoagulant properties, like garlic and ginger, also carry a risk of increased bleeding when combined with these medications. For ACE inhibitors, interactions with NSAIDs or diuretics can increase risks like renal impairment, hyperkalemia or reduced antihypertensive effects. Potassium-rich foods further elevate hyperkalemia risks with ACE inhibitors. Close monitoring

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    Anticoagulants, ACE Inhibitors

    Uploaded by

    Gwyneth Cartalla
    52 views2 pages
    This document summarizes potential drug-drug and drug-food interactions for several common anticoagulant and ACE inhibitor medications. It notes that certain drugs may decrease the metabolism or clearance of anticoagulants like apixaban and dabigatran, increasing their anticoagulant effects and bleeding risk. Foods and supplements containing compounds with anticoagulant properties, like garlic and ginger, also carry a risk of increased bleeding when combined with these medications. For ACE inhibitors, interactions with NSAIDs or diuretics can increase risks like renal impairment, hyperkalemia or reduced antihypertensive effects. Potassium-rich foods further elevate hyperkalemia risks with ACE inhibitors. Close monitoring

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    This document summarizes potential drug-drug and drug-food interactions for several common anticoagulant and ACE inhibitor medications. It notes that certain drugs may decrease the metabolism or clearance of anticoagulants like apixaban and dabigatran, increasing their anticoagulant effects and bleeding risk. Foods and supplements containing compounds with anticoagulant properties, like garlic and ginger, also carry a risk of increased bleeding when combined with these medications. For ACE inhibitors, interactions with NSAIDs or diuretics can increase risks like renal impairment, hyperkalemia or reduced antihypertensive effects. Potassium-rich foods further elevate hyperkalemia risks with ACE inhibitors. Close monitoring

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    Download as docx, pdf, or txt
    52 views2 pages

    Anticoagulants, ACE Inhibitors

    Uploaded by

    Gwyneth Cartalla
    This document summarizes potential drug-drug and drug-food interactions for several common anticoagulant and ACE inhibitor medications. It notes that certain drugs may decrease the metabolism or clearance of anticoagulants like apixaban and dabigatran, increasing their anticoagulant effects and bleeding risk. Foods and supplements containing compounds with anticoagulant properties, like garlic and ginger, also carry a risk of increased bleeding when combined with these medications. For ACE inhibitors, interactions with NSAIDs or diuretics can increase risks like renal impairment, hyperkalemia or reduced antihypertensive effects. Potassium-rich foods further elevate hyperkalemia risks with ACE inhibitors. Close monitoring

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    Anticoagulants

    Drugs Drug-Drug Interaction Effects Drug-Food Interaction Effects

    Apixaban Abiraterone Decreased metabolism of Grapefruit, Herbs and Increase the risk of bleeding.
    Apixaban. supplements with
    anticoagulant activity (garlic,
    ginger, ginkgo biloba), St.
    John’s Wort.
    Dabigatran Acetylsalicylic acid Increased anticoagulant Herbs and supplements with Increase the risk of bleeding.
    activities of Dabigatran. anticoagulant activity (garlic,
    ginger, bilberry).
    Edoxaban Benmoxin Severity of bleeding and Herbs and supplements with Increase the risk of bleeding.
    haemorrhage. anticoagulant activity (garlic,
    ginger, bilberry).
    Rivaroxaban Cangrelor Increased anticoagulant St, John’s Wort, and Herbs Decreased level of the
    activities of Rivaroxaban. and supplements with medication, and increases the
    anticoagulant activity (garlic, risk of bleeding.
    ginger, bilberry).
    Warfarin Aspirin Excessive blood thinning that Too much consumption of It makes warfarin less
    may lead to serious bleeding. green, leafy vegetables that effective.
    are rich in vitamin K (lettuce,
    spinach, broccoli)

    ACE Inhibitors

    Drugs Drug-Drug Interaction Effects Drug-Food Interaction Effects

    Benazepril Acemetacin Increased risk of renal failure, Potassium-containing Increase the risk of
    hyperkalemia, and products hyperkalemia
    hypertension.
    Captopril Digoxin Decreased clearance of Moderately high or high High levels of potassium in
    digoxin from plasma in potassium dietary intake the blood.
    patients with heart failure. (bananas,
    Enalapril Acipimox Increased risk of myopathy, Hypertensive herbs (bayberry, Additive hypertensive effects
    rhabdomyolysis, and cayenne), and Potassium- may occur, and the risk of
    myoglobinuria. containing products. hyperkalemia is increased.
    Fosinopril Acyclovir Acyclovir may decrease the Hypertensive herbs (bayberry, May attenuate
    excretion rate of Fosinopril, cayenne), potassium- antihypertensive effect and
    resulting in higher serum containing products, and salty the risk of hyperkalemia is
    level. foods. increased.
    Lisinopril Acetylsalicylic acid Decreased effect of Hypertensive herbs (bayberry, May attenuate
    Lisinopril. cayenne), potassium- antihypertensive effect and
    containing products, and salty the risk of hyperkalemia is
    foods. increased.
    Moexipril Acebutolol Risk of QTc prolongation can Hypertensive herbs (bayberry, May attenuate
    be increased. cayenne), potassium- antihypertensive effect and
    containing products, and salty the risk of hyperkalemia is
    foods. increased.
    Perindopril Acetazolamide Increase the excretion rate of Hypertensive herbs (bayberry, May attenuate
    Perindopril which could result cayenne), potassium- antihypertensive effect and
    in lower serum level and a containing products, and salty the risk of hyperkalemia is
    reduction in efficacy. foods. increased.
    Quinapril Aldesleukin Severity of adverse effects Fatty foods, hypertensive Risk of hyperkalemia, and
    can be increased. herbs, potassium-containing may attenuate the
    products, and salty foods. antihypertensive effect.
    Ramipril Alfentanil Decreased antihypertensive Potassium-containing Increased risk of
    activities of Ramipril. products. hyperkalemia.

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