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Health Care Epidemiology and Infection Prevention and Control
Health Care Epidemiology and Infection Prevention and Control
Most Common Types of Health care-Associated Infections Increased use of less highly trained health care
workers, who are often unaware of infection
According to the CDC, the five most common types of control procedures
HAIs in U.S. hospitals are the following: Increased use of anti-inflammatory and
1. C. ~associated gastrointestinal disease (antibiotic- immunosuppressant agents such as radiation,
associated diarrhea [AAD]) steroids, anticancer, chemotherapy, and ant
2. UTIs, most of which are catheter related lymphocyte serum
3. Surgical site infec1ions Overuse and improper use of indwelling medical
4. Lower respiratory tract infectious (primarily devices
pneumonia)
5. Bloodstream infections (septicemia)
What Can Be Done to Reduce the Number of Health Care-
Associated infections?
The most common types of HAl in the United States are C.
difficile-associated diarrhea, UTis, surgical site infections, It is critical for all health care workers to be aware of the
lower respiratory 1ract infections, and bloodstream problem of HAis and to take appropriate measures to
infections. minimize the number of such infections that occur within
health care facilities.
C. Difficile is the most common cause of health care-
associated gastrointestinal infections Handwashing is the single most important measure to
reduce the risks of transmitting pathogens from one patient
to another or from one anatomic site to another on the
Patients most likely to develop health care-associated same patient. Because it specifically pertains to health
infections care personnel, handwashing is discussed in the section
Patient whose immune systems have weakened by age, entitled "Standard Precautions."
underlying disease/medical/surgical treatments are most
likely risks to infections. Intensive care unit (ICU) is the The following are commonsense, every day, handwashing
highest infection rate in the hospital area. Moreover, Health guidelines that pertain to everyone:
Associated Infections rates are 3x higher in adult and
pediatric ICU’s than elsewhere in hospital. Wash your hands before you:
Prepare or eat food
These are the most vulnerable patients in the hospital Treat a cut or wound or tend to someone who is
settings: sick.
Insert or remove contact lenses
Elderly patients
Women in labor and delivery Wash your hands after you:
Premature infants and newborns Use the restroom
Surgical and burn patients Handle uncooked foods, particularly raw meat,
Patients with diabetes or cancer poultry, or fish
Patients with cystic fibrosis Change a diaper
Patients having an organ transplant Cough, sneeze, or blow your nose
Patients receiving treatment with steroids, Touch a pet, particularly reptiles and exotic
anticancer, drugs, ant lymphocyte serum, or animals
radiation Handle garbage
Immunosuppressed patients (are specially likely Tend to someone who is sick or injured
to develop HAIs)
Patients who are paralyzed Wash your hands in the following manner:
Patients undergo in renal dialysis or urinal Use warm or hot running water
catheterization Use soap
Patients with indwelling devices such as Wash all surfaces thoroughly, including wrists,
endotracheal tubes, central venous, and arterial palms, back of hands, fingers, and under
catheters and synthetic implants fingernails (preferably with a nail brush)
Rub hands together for at least 10 to 15 seconds
MAJOR FACTORS CONTRIBUTING TO HEALTH CARE- When drying, begin with your forearms and work
ASSOCIATED INFECTIONS toward your hands and fingertips, and pat your
skin rather than rubbing to avoid chapping and
3 MAJOR FACTORS: cracking
1. Increasing number of drug-resistant pathogens
2. Failure of health care personnel to follow infection Handwashing is the single most important measure to
control guidelines reduce risks of transmitting pathogens from one patient to
3. Increased number of immunocompromised another or from one anatomic site to another on the same
patients patient
Disinfection
Categories of Disinfectants
Chemical Sterilant
Kill bacterial spores with prolonged exposure
times 3 - 12 hours
High-Level disinfectant
Kill all microbes, except large number of
bacterial spores
Intermediate-level disinfectant
Might kill mycobacteria, vegetative
bacteria, most viruses, and most fungi, but
do not necessarily kill bacterial spores.
Low-Level disinfectant
Kill most vegetative bacteria, some fungi,
and some viruses within 10 mins of exposure.
Critical Items
Surgical Asepsis
Practiced in operating room, in labor and delivery
area, and during invasive procedure.
Personal Protective Equipment Eye protection and masks are removed after
gloves are removed
Gloves
Protect both patient and health care personnel Patient-care and Environmental control
Must be changed between tasks and procedures
on the same patient whenever there is risk of Patient-care equipment
transferring microorganisms from one body site to Organic material should be removed from
another. medical equipment and Instruments such as
Always remove gloves promptly after use and blood, body fluids, secretions, and excretions.
before going to another patient. Equipment's and devices must be handled in a
Wash hands immediately after removing gloves. manner that will protect health care workers and
the environment from potentially infectious
material.
Isolation Gown Items such as commodes, intravenous pumps,
Worn in conjunction with gloves and with other and ventilators must be thoroughly cleaned and
PPE disinfected before use by or on another patient.
First piece of PPE to be donned
Protect health care worker’s arms and exposed
body areas and prevent contamination with Environmental control
blood, body fluids, and other potentially infectious
material The hospital must have employees that will comply
When applying Standard Precautions, isolation adequate procedures for the routine care, cleaning, and
gown is worn only if contact with blood or body disinfection of environmental surfaces.
fluid
When Contact Precautions are used, donning of Linens
both gown and gloves upon room entry is
indicated Textiles, such as bedding, towels, and patient gowns, that
Isolation gowns should be removed before have become soiled with blood, body fluids, secretions, or
leaving the patient-care area excretions must be handled, transported, and laundered in
It should be removed in a manner that prevents a safe manner.
contamination of clothing or skin and the outer
“contaminated” side of the gown is turned Disposal of sharps
inward and rolled into a bundle and discarded Needle stick injuries and injuries resulting from broken
into a designated container for waste or linen glass and other sharps are the primary manner in
which health care workers become infected with
Mask pathogens. Standard Precautions include guidelines
They are worn by health care personnel: regarding the safe handling of such C items.
Protect them from contact with infectious
material from patients The following are desirable characteristics of needle safety
Engaged in procedures requiring sterile technique features:
to protect patients from exposure to pathogens
that maybe present in a health care worker’s It is as simple to use as possible, requiring little
mouth or nose training to use it effectively.
Placed on coughing patient to limit potential It is an integral part of the device, not an
dissemination of infectious respiratory secretions accessory.
It provides a barrier between the hands of the
health care worker and the needle after its use.
Respiratory Protection It allows the worker's hands to remain behind the
Requires the use of a respirator with N95 or higher needle at all times.
filtration to prevent inhalation of infectious It is in effect before disassembly and remains in
particles effect after disposal to protect users and trash
N95 respirators are tight-fitting, adjustable masks handlers and for environmental safety.
that are designed to protect against small Contaminated needles and other contaminated
droplets of respiratory fluids and other airborne sharps must not be bent, recapped, or removed,
particles and shearing or breaking of needles is prohibited.
It filters at least 95% of airborne particles
Powered air-purifying respirators are Transmission Based Precautions
recommended when working with patients with
tuberculosis, viral hemorrhagic fever infections Used to help stop the spread of germs from one person to
such as Ebola, smallpox, and during the another. The goal is to protect patients, their families, other
performance of aerosol-generating procedures visitors, and healthcare workers—and stop germs from
on patients with avian or pandemic influenza spreading across a healthcare setting.
Precautions are used in addition to Standard Pre Droplets are produced primarily as a result of
caution coughing, sneezing, and talking as well during
hospital procedures such as suctioning and
bronchoscopy
Contact Precautions Droplet Precautions are used for particles that are
larger than 5m in diameter
Used for infections, diseases, or germs that are Droplets do not remain suspend in the air
spread by touching the patient or items in the Droplets Precaution must be used for patients
room. known to be infected with microbes transmitted
Contact Transmission is the most frequent by droplets that can generate in the ways
previously mentioned
transmission of Health care-associated infections
(HAIs). Infectious Disease or Conditions in Droplet Precautions
Contact Precautions are used for the patients
suspected to be infected or colonized with Influenza
epidemiologically important pathogen that can Meningitis (haemophilus influenza type b – children,
be transmitted by direct or indirect contact Neisseria meningitides – adolescence,
Example of infectious agents requiring contact precautions streptococcus pneumoniae –elderly)
include: Mumps
• Multidrug- resistant bacteria Pertussis
• CRE - Carbapenem-resistant Enterobacterales Viral hemorrhagic fevers (Lassa, Ebola, Marburg,
• C. Difficile – associate diarrhea Crimean-Congo fever viruses)
• Respiratory viral infections - Have common features they affect many
organs, they damage the blood vessels,
Infectious Disease or Conditions in Contact Precautions and they affect the body's ability to
regulate itself.
Oozing cellulitis – soaks lines
Open wounds – soaks dressing / not contaminated Droplet precaution signs
Uncontained urine – soil environment Handy hygiene before entering
Uncontained respiratory secretions – soils Mask with eye shield/ mask
environment Hand hygiene upon exiting
Diarrhea and unable to self – toilet
Respiratory syncytial virus / RSV (infants, young
Airborne Precaution
children, and immunocompromised adults)
MDRO/ Multidrug resistant organism (Carbapenem- Used for diseases or very small germs that are
resistant Enterobacterales, Multi drug resistant - spread through the air from one person to
Acinetobacter, Methicillin-resistant Staphylococcus another
aureus, Vancomycin Resistant Enterococci) (Examples: tuberculosis, measles, chickenpox).
Involves either airborne droplet nuclei or dust
Cystic Fibrosis
particles containing a pathogen
They are used when particles are 5 less in
diameter
Infectious Disease or Conditions in Contact Enteric They remain suspended in the air because of their
small size
Clostridium difficile (patient remains in precaution Applied to patients known or infected with
for duration of hospitalization) epidemiologically important pathogens that can
be transmitted by the airborne route such as
Norovirus (can remove from precautions once
tuberculosis or measles
asymptomatic for 2 days)
Infectious Disease or Conditions in Airborne Precaution
Contact Precautions and Contact Enteric Precautions Signs Measles
Hand Hygiene (Before entering room) Tuberculosis (active or rule out)
Gown Chickenpox (Varicella)
Gloves Shingles (Zoster)
Hand Hygiene (Upon exiting room)
Protective Environment (PE) rooms are hospital Transmission of pathogens by fomites can be prevented by
rooms designed to protect a high-risk observing the following rules:
immunocompromised patient from human and
environmental airborne pathogens. These are Use disposable equipment and supplies wherever
positive pressure rooms intended to keep patients possible Disinfect or sterilize equipment as soon as
safe during recovery from cancer treatment or possible after use
stem-cell transplant. The patients who use it most Use individual equipment for each patient
often are those who have received transplant, Use electronic or glass thermometers fitted with
leukemia and immature infants. These patients onetime use. Disposable covers or use disposable,
can be protected in a Protective Environment single-use thermometers; electronic and glass
Certain in patients that are especially vulnerable thermometers must be cleaned or sterilized on a
in infection, particularly to environmental fungal regular basis, following manufacturer's instructions
infections Empty bedpans and urinals, wash them in hot
The protective environment is a single room. water, and store them in a clean cabinet
Appropriate standard and transmission based between uses
precautions are strictly enforced Place bed linen and soiled clothing in bags to be
The vented air entering the room is passed sent to the laundry
through High Efficiency particular air (HEPA) filters.
All sweepings. Solid or liquid wastes, refuse and Role of the Microbiology Laboratory in Health care
garbage shall be removed. Epidemiology
The medical facility's infection control program
must address the handling and disposal of The following are some of the ways in which CML personnel
potentially contaminated items. participate in health care epidemiology and infection
control:
Infection Control in Dental Health Care Setting By monitoring the types and numbers of
pathogens isolated from hospitalized patients. In
Development of a written infection control most hospitals, such monitoring is accomplished
program and training of dental health care using computers and appropriate software
personnel, immunizations, exposure prevention programs called Laboratory Information Systems.
and post exposure management, work restriction By performing antimicrobial susceptibility testing,
caused by medical conditions, and maintenance detecting emerging resistance patterns, and
of records, data management, and preparing
confidentiality
Preventing transmission of blood borne pathogens
Hand hygiene and PPE
Contact dermatitis and latex hypersensitivity
Sterilization and disinfection of patient-care items
Environmental infection control
Special considerations, such as dental hand
pieces, dental radiology, an aseptic technique
for parenteral medications, oral surgical
procedures, handling of biopsy specimens and
extracted teeth, dental laboratory, and patients
with tuberculosis