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  • Draft Kerangka Teori 30 Juli 2018 - Rev2

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    debby nirmasari
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    This document discusses a study on the effects of propolis and vitamin D3 on arterial stiffness and vein distensibility in patients with chronic kidney disease. It notes that chronic inflammation in CKD leads to arterial stiffness and vein distensibility through various pathways, and that propolis and vitamin D3 may help reduce arterial stiffness and improve vein distensibility by combating inflammation and oxidative stress.

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    Draft Kerangka Teori 30 Juli 2018_rev2

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    This document discusses a study on the effects of propolis and vitamin D3 on arterial stiffness and vein distensibility in patients with chronic kidney disease. It notes that chronic inflammation in CKD leads to arterial stiffness and vein distensibility through various pathways, and that propolis and vitamin D3 may help reduce arterial stiffness and improve vein distensibility by combating inflammation and oxidative stress.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    Download as docx, pdf, or txt
    15 views3 pages

    Draft Kerangka Teori 30 Juli 2018 - Rev2

    Uploaded by

    debby nirmasari
    This document discusses a study on the effects of propolis and vitamin D3 on arterial stiffness and vein distensibility in patients with chronic kidney disease. It notes that chronic inflammation in CKD leads to arterial stiffness and vein distensibility through various pathways, and that propolis and vitamin D3 may help reduce arterial stiffness and improve vein distensibility by combating inflammation and oxidative stress.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    of 3

    engaruh Propolis dan Vitamin D3 terhadap Arterial Stiffness

    dan Vein Distensibilitypada Penyakit Ginjal Kronis

    PembimbingAkademik:

    Prof. Dr.Suradi, dr,Sp.P(K)

    RencanaPromotor:

    Prof. Dr. BambangPurwanto, dr, Sp.PD-KGH

    Penyusun:

    Darmawan Ismail, dr, Sp. BTKV


    CKD

    Indoxyl sulfate 1 α OHase Klotho Ekskresi P


    Inflamasi kronis

    IL-1β IL-6 TNFα


    1, 25-dihydroxyvitamin D FGF23
    NAD(P)H oksidase
    Gluthation
    PTH
    P36 ERK 1/2
    P
    Ca

    NF-kβ ROS Erk 1/2 Caspase-3


    MMP 9
    JNK Mitokondria
    Runx2

    TGF β1

    ICAM-1
    VCAM-1
    Mineralisasi ECM

    Sklerosis

    Arterial Stiffness VeinDistansibility


    CKD

    Indoxyl sulfate 1 α OHase Klotho Ekskresi P


    Inflamasi kronis

    IL-1β IL-6 TNFα


    1, 25-dihydroxyvitamin D FGF23
    NAD(P)H oksidase PTH
    P50 OSTEOKLAST
    P65
    Vit D3
    P36 ERK 1/2 DEMINERALISASI TULANG

    Ca

    Ca P
    Propolis
    IKB
    NF-kβ ROS Erk 1/2 Caspase-3
    MMP 9
    JNK Mitokondria
    Runx2

    TGF β1

    VCAM-1 DMC

    ECM

    KOLAG

    Sklerosis

    Arterial Stiffness VeinDistansibility

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