1.

Which of the following is not a key cause of

neutropenia? 7. Nucleus stains deeply; irregular and often
a. Starvation assumes shapes comparable to such letters as E,
b. Marrow failure Z, and S; separate nuclei normally are segments
c. Collagen vascular disorders of nuclear material connected by delicate
d. Any overwhelming allergic reaction filaments.
a. Monocytes
2. Affects all ages but most common form of acute b. Eosinophils
leukemia during first few months of life and c. Basophils
often resembles acute infection at presentation. d. Neutrophils
a. Juvenile chronic myelomonocytic leukemia
b. Chronic lymphocytic leukemia 8. Polyclonal serum IgM is increasedin
c. Acute myeloid leukemia predominantly female smokers in
d. None of the above postsplenectomy state
a. Persistent polyclonal B cell lymphocytosis
3. Lack of TdT and presence of CD19, CD20, CD22. b. Chronic lymphocytosis
a. Burkitt lymphoma c. Acute infectious lymphocytosis
b. Primary effusion lymphoma d. None of the above
c. Mantle cell lymphoma
d. Follicular lymphoma 9. Which of the following is not associated with
Chronic Myelogenous Leukemia?
4. Sore throat, prolonged malaise, atypical a. Young and middle-aged adults
lymphocytosis with the presence of large b. Anemia and weight gain
transformed lymphocytes c. Spleen enlarges progressively
a. Pertussis d. Excessive bleeding or bruising in later stages
b. Chronic lymphocytosis
c. Retrovirus-associated diseases and 10. Chronic progressive clonal panmyelosis
conditions characterized by megakaryocytic and
d. Infectious mononucleosis granulocytic hyperplasia with varying degrees of
reactive fibrosis of the marrow and
5. Extensive deposition of collagen extramedullary hematopoiesis
a. Fibrosis a. Thrombocythemia
b. Scar formation b. Polycythemia vera
c. Regeneration c. Primary myelofibrosis
d. None of the above d. None of the above

6. Decrease in circulating monocytes below the 11. Rare autosomal dominant condition with pale
lower reference value blue cytoplasmic ribosomal inclusions
a. Monocytosis resembling Dohli bodies
b. Monocytopenia a. Alder-Reilly anomaly
c. Lymphocytosis b. May-Hegglin anomaly
d. Eosinophilia c. Pelger-Huet anomaly
 d. None of the above a. Chediak-Higashi syndrome
b. Specific granule deficiency
12. Follicle-like structures with centrocytes and c. Chronic granulomatous disease
varying numbersof centroblasts d. Myeloperoxidase deficiency
a. Follicular lymphoma
b. Mantle cell lymphoma 17. Mast cells filling the papillary dermis and
c. B cell prolymphatic leukemia extending into reticular dermis. Multifocal,
d. None of the above sharply demarcated compact aggregates of
mast cells. Tryptase positive round cell
13. A patient with low serum erythropoietin and infiltrates.
BM biopsy showing panmyelosis with a. Mastocytosis
prominent erythroid and megakaryocytic b. Thrombocythemia
proliferation also has presence of JAK2 B617F. c. Myelofibrosis
a. Polycythemia vera d. Polycythemia vera
b. Thrombocythemia
c. The diagnosis can’t be given 18. Hypercellular marrow with granulocytic
d. None of the above hyperplasia and a myeloid/erythroid ratio up to
20:1
14. Clonal myeloproliferative disorder primarily a. Chronic myelogenous leukemia
affecting the megakaryocytic lineage with b. Chronic neutrophilic leukemia
principal manifestation of sustained c. Polycythemia vera
thrombocytosis d. All of the above
a. Thrombocythemia
b. Polycythemia vera 19. Elevated hemoglobin. Presence of JAK2 B617F
c. Primary myelofibrosis or similar mutation such as JAK2 exon 12
d. None of the above mutation. Low serum erythropoietin.
a. Chronic myelogenous leukemia
15. Which cell morphology is associated with b. Chronic neutrophilic leukemia
acute myelomonocytic leukemia? c. Polycythemia vera
a. Myeloblasts, <3% positive for SBB, MPO, or d. All of the above
ANA
b. Myeloblasts ≥90% of nonerythroids in BM, 20. Pale blue, oval cytoplasmic remnants of
≥3% positive for MPO ribosomes.
c. Monocytic and granulocytic cells, each 20%- a. Pelger-Huet anomaly
80% b. Doyle bodies
d. None of the above c. Cytoplasmic vacuoles
d. May-Hegglin anomaly
16. Partial oculocutaneous albinism, photophobia,
immune deficiency, neurologic defects and 21. CLL/SLL may transform into:
frequent pyogenic infections. Giant granules a. Prolymphocytic leukemia
representing giant fused lysosomes. Mutation in b. Richter’s syndrome
the gene CHS/beige, coding for the CHS1. c. a and b
 d. none of the above

22. Which of the following cannot be a key cause of

basophilia?
a. Chronic hemolytic anemia
b. Ulcerative colitis
c. Varicella infection
d. Recovery from neutropenia

23. Which of the following is a localized variant of

mastocytosis?
a. Diffuse cutaneous mastocytosis
b. Mastocytoma
c. Systemic mastocytosis
d. None of the above

24. Which of the following is not associated with

follicular lymphoma?
a. Low-grade
b. Incurable
c. Transforms to diffuse large B cell lymphoma
d. HIV

25. Diffuse infiltrate with pushing borders of

medium-sized relatively uniform cells with
round to oval nuclei containing 3-5 prominent
nucleoli
a. Burkitt lymphoma
b. Plasmablastic lymphoma
c. Primary effusion lymphoma
d. None of the above