Automated immunoassay system

Specifications
Measurement principle Chemiluminescence enzyme immunoassay (CLEIA)
Parameters simultaneously measured Up to 24 items
Throughput 100 tests/hour
Reaction time Approximately 17 minutes (from sampling to measurement result report)
Number of sample position Up to 30 samples
Number of emergency sample position 1 sample Automated immunoassay system
Sample volume 10 µL to 30 µL
Sample container Test tube (open) Diameter (outer diameter) 13 mm to 16 mm
Height 75 mm to 100 mm
Dead volume Depth of serum or plasma component is 5 mm and more from the liquid level
Sample cup Conical 4 mL
Dead volume 0.15 mL
Reagent management function R1, 2, 3 reagents, luminescent substrate set: RFID
Line washer, wash solution, probe washer: bar code
Data storage Up to 100,000 samples
Quality control Select either L-J management or X-bar management
External output RS232C, LAN
Power supply specifications Measurement part: AC100V to 240V, Compressor: AC100V to 117V, rated frequency: 50Hz/60Hz, maximum
electric power consumption (Main unit, including a sampler): 1200 VA, maximum electric power consumption
(Compressor): 230 VA (50 Hz), 280 VA (60 Hz)
Printing method External printer
Accessory Handheld bar code reader
Options Drain tank, indicator lamp

Specifications
Main unit Dimension Approx. 1018 mm (W) × 1089 mm (D) ×1295 mm (H)
(including a sampler)
Weight Approx. 320 kg
Compressor Dimension Approx. 280 mm (W) × 355 mm (D) × 400 mm (H)
Weight Approx. 17 kg

Quick support of network utilization - SNCS*1

SNCS is a service that enables customers to connect their analytical equipment to the Sysmex Technical
Support Center via the Internet, providing real-time external quality control, online support, Web-based
information delivery, and precision management and automatic monitoring. The real-time support will
contribute to construction of more comfortable and safer use environment for customers.
*1 SNCS: Sysmex Network Communication Systems (A separate [paid] agreement is needed to use this service)

Sysmex Corporation Sysmex (Malaysia) Sdn Bhd Sysmex Vietnam Co., Ltd
1-5-1, Wakinohama-Kaigandori, Chuo-ku, Kobe, 11A & 15, Jalan PJS 7/21, Bdr Sunway, Unit 802, Centre Point Bldg, 106 Nguyen Van Troi St,
Hyogo 651-0073, Japan 47500 Subang Jaya, Selangor, Malaysia Phu Nhuan Dist, Ho Chi Minh City, Vietnam
Tel +81 (78) 265-0500 Fax +81 (78) 265-0524 Tel +60 (3) 5637-1788 Fax +60 (3) 5637-1688 Tel +84 (8) 3997-9400 Fax +84 (8) 3997-9405
www.sysmex.co.jp www.sysmex.com.my www.sysmex.com.vn

Sysmex Asia Pacific Pte Ltd Sysmex (Thailand) Co., Ltd Sysmex Vietnam Co., Ltd (Hanoi Branch)
9, Tampines Grande #06-18, 12th Floor, Tonson Tower, Floor 10, Vinaconex Building, 34 Lang Ha St,
Singapore 528735, Singapore 900 Ploenchit Road, Lumpini, Dong Da Dist, Ha Noi, Vietnam
Tel +65 6221-3629 Fax +65 6221-3687 Pathumwan, Bangkok 10330, Thailand Tel +84 (4) 3776-7020 Fax +84 (4) 3776-7022
www.sysmex-ap.com Tel +66 (2) 635-5777 Fax +66 (2) 257-0530 www.sysmex.com.vn
www.sysmex.co.th
Sysmex India Pvt. Ltd Sysmex Australia Pty Ltd
1002, Damji Shamji Business Galleria, Sysmex Philippines Inc. Level 9, Avaya House, 123 Epping Road
10th Floor, LBS Marg 30th Floor MDC 100 Bldg, E. Rodrigues Jr. Ave, cor North Ryde 2113 NSW, Australia
Kanjurmarg (West), Mumbai 400 078, India Eastwood Ave, Bagumbayan, Tel +61 (2) 8875-7700 Fax +61 (2) 8875-7777
Tel +91 (22) 6112-6666 Fax +91 (22) 2577-6790 Quezon City, Philippines www.sysmex.com.au
www.sysmex.co.in Tel +63 (2) 621-2460 Fax +63 (2) 621-2432
www.sysmex.com.ph
PT Sysmex Indonesia
Cyber 2 Tower, 5th Floor, Unit E, Sysmex New Zealand Ltd
Jl. HR. Rasuna Said, Blok X5 No. 13, 382 - 386 Manukau Rd, PO Box 26-085, Epsom,
Jakarta Selatan 12950, Indonesia Auckland 1344, New Zealand
Tel +62 (21) 3002-6688 Fax +62 (21) 3002-6699 Tel +64 (9) 630-3554 Fax +64 (9) 630-8135
www.sysmex.co.id www.sysmex.co.nz

*Appearance and specifications are subject to change without notice. D14101001I

High specifications & space- saving
Realize flexible response
Rapid High
HISCL-800 measurement sensitivity

Inheriting the concept of HISCL series such as quick measurement,

high sensitivity, minute samples, and excellent usability,

HISCL-800 could realize downsizing.

This led to flexible utilization in accordance with various types

of clinical laboratory test sites

This is a full automated immunoassay system satisfying leading edge laboratory needs such as Minute Excellent
improvement of service for patients and realization of increased efficiency/high value-added test section. sample usability
Meet medical needs for greater sophistication and diversity by excel lent performance and the cutting-edge technology Rapid
measurement
High
sensitivity

[Technical capabilities]
Minute Excellent
sample usability

Rapid
measurement Only 17-minute reaction time for all items High
sensitivity Provide reliable measurement results
Realize pre-medical care test by the Speedup antigen-antibody reaction by Chemiluminescent substrate CDP-Star® Reduction of background by
17-minute reaction system liquid phase-liquid phase reaction is adopted B/F separation
From start of a first-order antigen antibody reaction to output of A liquid phase-liquid phase reaction system is adopted for the By adopting the chemiluminescent substrate CDP-Star®, which In addition to dispersion process during the washing process,
the test results, it takes only 17 minutes for all items. It first-reaction. Although antibodies are connected to a tube or shows strong luminescence intensity by dephosphorylation of separation efficiency of reacted products from unreacted
contributes service improvement for patients by realizing magnetic particles and flexibility is restricted in a liquid the substrate by alkaline phosphatase, sensitive measurement products (B/F separation) is improved and background effect is
pre-medical care test with increased efficiency of testing phase-solid phase reaction, encountering chance with antigens system is realized. reduced.
operation and quicker reporting of results. will increase in a liquid phase, so that antigen antibody
reactants can be efficiently obtained.
CDP-StarⓇ
Rapid reaction in a liquid phase Trap to a magnetic particle

Improvement of reaction efficiency by Antigen

Luminescent substrate A Magnet

the reaction system at 42ºC Antibody

1.0E-16 1.0E-17 1.0E-18 1.0E-19 1.0E-20
Detection Limit (mol/assay) Magnetize Wash Separate Magnetize
By setting the whole reaction system at 42ºC, encounter Magnetic
frequency and enzyme reaction efficiency were increased. particle
Combing with merits of the liquid phase-liquid phase reaction,
more efficient reaction can be realized. Wide-range detection by loading an Carry over measures by
optical filter membrane filters
Strong luminescence from CDP-Star® can be efficiently detected Installing a membrane filter that wipes a nozzle by each
by using an optical filter. It enabled sensitive and wide-range dispensing of a sample, highly reliable measurement system
measurement. without carry over is constructed.

Reaction flow (measurement of HBs antibody)

R1: Biotin-binding anti HBs

monoclonal antibody (mouse)

R2: Streptavidin-binding
R3: ALP-labeled HBs
monoclonal antibody (mouse)
Output of measurement result

Measurement of
Minute
sample 10 μL to 30 μL of minute samples for all items
R4: Buffer luminescence intensity
with magnetic particle
HBs antigens
in a sample Wash solution Wash solution
R5: Chemiluminescent Accurate sampling Highly reliable dispense system
substrate CDP-Star®
using a special tip using a pressure sensor
0min 5min 10min 15min
17min By using a special disposable tip (photo), Sample suction is monitored using a pressure sensor (sample
minute sample volume (10 μL to 30 μL) of suctioning sensor). A highly reliable dispensing system that
sampling without contamination is achieved. detects an error of sample clogging or vacant suction for
Since it is a minute volume, more accurate preventing mismeasurement was constructed.
Avidin-biotin
reaction
measurement can be realized with a little
carried-in waste reaction product.

Disposable tip
First-order reaction First B/F separation Second-order reaction Second B/F separation Enzyme reaction (chemiluminescence)
Being designed from the viewpoint of users, greater efficiency in the field of test is fostered. Rapid
measurement
High
sensitivity

[Usability]
Minute Excellent
sample usability

Excellent
usability Promote business efficiency with excellent
User friendly interface
A 21-inch wide touch panel color display was adopted and
usability was improved with large icons. The software functions
supporting routine works such as display of remaining amount
of reagents or progress status are also satisfied. Since it adopts
the same interface with HISCL-5000, it is easier to use them
together.
usability
RFID is adopted for reagents management Cooling of reagents/24-hour management The STAT port deals with emergent/
Radio Frequency Identification (RFID) is adopted for information and automated wake-up function interrupt measurement
management of reagents. Accurate data reading is possible regardless
The reagent setting part has a 24-hour reagent cooling function. The STAT port located at the center of rack supply/draining part can
of conditions of a reagent storage cabinet.
It also has a wake-up function that enables smooth measurement be loaded at any time during operation. It preferentially measures
at the start of testing work. in emergency without
Reagents information management by RFID complex manipulation.

Cooling tank
for reagents

RFID
antenna

Menu screen

Auto alignment/supply functions of R1 to R3 reagents can be simultaneously High performance in a small footprint 100V power supply is available
special tips and cuvettes installed up to 24 sets. In comparison with HISCL-5000, space-saving was realized by Since versatile 100V electrical supply system is adopted, it can be
reducing width of the device by approximately 60%. It is used in various laboratories without taking time for special
Disposable tips and reaction cuvettes are automatically R1 to R3 reagents can be simultaneously installed up to 24 sets.
compact but useful in various environments with high electric work.
aligned/provided by just being loaded into a supply part. Four sets of reagent bottles can be accessed at once by just simple
performance.
operation of setting.
Also, the automated Common reagents can be replaced
open-close system
of a reagent bottle during measurement operation
cap can prevent
Each wash solution and chemiluminescent substrate can be
deterioration of the
replaced during measurement. It is an easy operation by setting
reagents.
only.
Cuvette supply part Tip supply part

Sample delivery line that enables diverse workflow Examples of usage of HISCL-800
By adopting a side sampling system, it can be connected to the Example of connection to the delivery line (with automated retest)
sample delivery line. It will improve the work flow and increase As a main device In accordance with operational needs
Export
efficiency of the testing operation.
Import

Front Back Front Back

＋ ＋

Delivery line along the side of a device → There is a passing line.

Delivery line between devices  Retest buffer
* Please make inquiries about measurable items separately.