Cushing’s 

= tooo much Cortisol, or high dose steroids   

~ Steroid Side Effects~  Moon Face,  Buffalo hump,   weight gain,   glaucoma,   diabetes,   osteoporosis,  
impaired healing

Addison’s = not enough cortisol /  steroids stopped abruptly   

Fludrocortisone 
 MOA: mineralcorticoid that mimics aldosterone

Raynaud’s CCB    like ER Nifedipine

Celiac Gluten: Wheat, barley, rye     

 (rice & oats DON’T have gluten!!!)

LUPUS immunosuppressants

+ANA ● Belimumab Benlysta IV MOA: B-cell activator

● Sunscreen
+anti-ssDNA ●  Hydroxychloroquine Plaquenil
● Cyclophosphamide MOA: alkylating agent
+anti-dsDNA ● Azathioprine
● Mycophenolate Mofetil
● Cyclosporine MOA: IL-2

 Drugs  that  CAUSE LUPUS →

Methimazole         
Procainamide       
Isoniazid        
Anti-TNF for RA etanercept (Enbrel),
Terbinafine  infliximab (Remicade), 
adalimumab (Humira), 
Methyldopa certolizumab pegol (Cimzia)
PTU and golimumab (Simponi)         
Hydralazine/BiDil
Minocycline

Myasthenia Gravis = LOW Ach

Cholinesterase inhibitors to Ach
BAD drugs:
Pyridostigmine Mestinon
● Antibiotics: AMG & FQ
● Magnesium salts
● Select anti-arrhythmics
Diarrhea, salivation, urination
● BB’s
● CCB’s
● Select antipsychotics
● Muscle relaxants
● Local anesthetics

Immune Modulator / T-lymphocyte suppressor Activator

MS -
SQ  daily or 3xweek : Glatiramer Acetate Copaxone ****GOOD PREGNANCY**** 
myelin
sheath
PO     Teriflunomide Aubagio
MRI                 Fingolimod Gilenya  MONITOR LOW HEART RATE
& EYES & XXCVD/STROKE

Interferon Beta Formulations  IM/SQ

 Depression/ SUICIDE
 If in FRIDGE, let stand @ROOMT TEMP
 DO NOT DISPELL AIR BUBBLE
INF Beta 1a    Avonex IM weekly      
Rebif SQ 3xWeek
          
INF Beta 1b    Betaseron/Extavia  SQ QOD

PEG-INF         Plegridy  
 titrate to SC Q2weeks  *least amt injections per month**

IV -mab’s
    
Nata-mab   [ Tysabri ]      binds to Integrin   
   Elem-mab  [ Lemtrada ]   humanized  -REMS
  Ocrel-mab  [ Ocrevus ]      humanized  -REMS

Sjodren’s Txt Dry mouth→   sugar-free chewing gum/lozenges w/

xylitol ; antimicrobial mouthwash;

Muscurinic AGONISTS:  Pilocarpine Salagen      

Cevimeline Evoxac    
XXnarrow GlaucomaXXX    
XXuncontrolled AsthmaXXXX

Txt Dry eyes → Cyclosporine [Restasis]

EMULSION   &  OTC artificial tears
 

1) Topical Steroids, Salicylic Acid

Psoriasis 2) Retinoid Tazaroten (Tazarac)
3) Coal Tar
4) Topical Vitamin D :
[Taclonex] = Calcipotriene  [Dovonex]  + Betamethasone
5) Calcineurin Inhibitors
● Topical Tacrolimus (Protopic)
● Topical Primcrolimus (Elidel)
6) Phosphodiesterase-4 Inhibitor
● Apremilast (Otezla)
7) –MABS: Interleukin Receptor Antagonists SQ Screen for TB!!!....cause Diarrhea
● Brodalumab Siliq  Suicide, REMS
● Guselkumab Tremfya
 ● Ixekizumab Taltz
● Secukinumab Cosentyx
● Tildrakizumab llumya
● Ustekinumab Stelara

Psoriatic
arthritis:     →   MTX   
→ Adalimumab Humira 
 
[also txts RA, Crohn’s, UC, ankylosing spondy!!!]

Cuprimine  [Penicillamine]    

Wilson’s Copper  & Lead poisoning empty stomach   

 inhibits IgG rheumatoid factor    
 also txts RA  /   causes rash