VANTOCIL™ Antimicrobial TECHNICAL

Intrinsic Activity of VANTOCIL IB BRIEF

VANTOCIL IB is a 20% formulation of the active agent Table 2.

poly(hexamethylenebiguanide) hydrochloride, also known as MIC (Minimum Inhibitory Concentration) against
PHMB. Two other products of similar activity, Gram-Positive Bacteria
VANTOCIL TG and VANTOCIL P are also available.
Micro-organism Strain No. VANTOCIL IB
(ppm product)
Bacillus cereus ATCC 9139 20
Table 1. Bacillus cereus ATCC 10876 160
MIC (Minimum Inhibitory Concentration) against Bacillus megaterium - 10
Gram-Negative Bacteria Bacillus polymyxa - 10
Bacillus subtilis NCIB 3610 1.5
Bacillus subtilis ATCC 6633 5
Micro-organism Strain No. VANTOCIL IB
Clostridium welchii - 60
(ppm product)
Corynebacterium acnes - 15
Acinobacter baumannii ATCC 19606 20
Enterococcus faecium NCIB 11508 10
Aeromonas hydrophila ATCC 7966 40
Enterococcus faecalis NCTC 775 20
Aeromonas hydrophila NCTC 8049 5
Enterococcus faecium NCIB 13192 1
Campylobacter jejuni ATCC 29428 40
Listeria monocytogenes ATCC 15313 30
Citrobacter freundii ATCC 8090 20
Listeria monocytogenes NCTC 11994 20
Edwardsiella tarda NCTC 11934 10
Mycobacterium smegmatis NCIB 8548 10
Enterobacter aerogenes ATCC 13048 10
Staphylococcus albus - 1
Enterobacter cloacae NCIB 8271 40
Staphylococcus aureus ATCC 6538 30
Enterobacter cloacae NCTC 11936 80
Staphylococcus aureus NCTC 6571 5
Escherichia coli NCIB 9132 160
Staphylococcus aureus (MRSA) NCTC 11940 2.5
Escherichia coli ATCC 11775 80
Staphylococcus aureus (MRSA) NCTC 12493 2.5
Escherichia coli NCTC 5934 5
Staphylococcus aureus NCTC 1803 20
Escherichia coli ATCC 9001 5
Staphylococcus epidermis ATCC 14990 10
Escherichia coli 0157:H7 NCTC 12900 80
Streptococcus faecalis - 5
Klebsiella aerogenes NCTC 9528 25
Streptococcus lactis NCTC 7944 20
Klebsiella pneumoniae ATCC 4352 30
Streptococcus pyogenes - 30
Klebsiella pneumoniae NCIB 11467 80
Lactobacillus casei - 30
Legionella pneumophila - 5
Proteus mirablis NCTC 10975 160 Table 3.
Proteus rettegeri NCTC 7475 160 MIC (Minimum Inhibitory Concentration) against Yeasts
Proteus vulgaris NCTC 4175 40
Pseudomonas aeruginosa ATCC 25668 310
Pseudomonas aeruginosa NCTC 10662 40 Micro-organism Strain No. VANTOCIL IB
Pseudomonas aeruginosa NCIB 6750 40 (ppm product)
Pseudomonas aeruginosa ATCC 15442 40 Candida albicans ATCC 10231 300
Pseudomonas aeruginosa ATCC 13388 60 Rhodotorula rubra NCYC 1659 7.5
Pseudomonas cepacia NCTC 10661 160 Saccharomyces cerevisiae ATCC 9763 300
Pseudomonas fluorescens ATCC 13525 40 Saccharomyces cerevisiae NCPF 3178 160
Pseudomonas perolens - 25
Pseudomonas putida - 25
Salmonella choleraesuis ATCC 13311 120 This work was carried out by the Microbiology Department
Salmonella dublin - 60
Salmonella poona NCTC 4840 40 of Arch Biocides.
Salmonella typhimurium ATCC 14028 160
Serratia marcescens NCIB 9523 160
Serratia marcescens NCTC 11935 30
Vibrio cholerae Non 0:1 NCTC 11348 5
Yersinia enterocolitica NCTC 10460 310

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Arch® Biocides
VANTOCIL™ Antimicrobial TECHNICAL
Intrinsic Activity of VANTOCIL IB BRIEF

Use biocides safely. Always read the label and product

information before use.

Some Arch Chemicals, Inc. biocides may not be registered

for certain uses in your country.

Any data relating to test organisms included in this

publication relates to standard laboratory test species and is
provided for information only. No claim of controlling
organisms in public health applications is made by the
inclusion of such data nor should it be implied.

VANTOCIL is a trademark, the property of Arch UK Biocides Ltd., a subsidiary of Arch Chemicals, Inc.

SAFE HANDLING INFORMATION

Refer to the Material Safety Data Sheet (MSDS) available from Arch Chemicals, Inc. for information on the safe use, handling and
disposal of this product.

FOR YOUR PROTECTION

Arch Chemicals, Inc. ("Arch") warrants that this product conforms to the chemical description on the label and that it is reasonably fit for the
purposes stated on the label when used in accordance with Arch’s directions under normal conditions of use. This warranty does not extend to
the use of this product contrary to label instructions, or under abnormal use conditions, or under conditions not reasonably foreseeable to Arch,
and the buyer or user assumes the risk of any such use. ARCH DISCLAIMS ALL OTHER WARRANTIES, EXPRESSED OR IMPLIED,
INCLUDING ANY WARRANTY OF MERCHANTABILITY. Statements herein, therefore, should not be construed as representations or warranties.

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