CURRICULUM VITAE

Dr. Muhammad Waseem Khan

Rahat Abad Colony, Bannu Road P.O Sheikh Yousaf
District D.I.khan, KPK, Pakistan.
Phone: 03459146065/03339965074
Email: khanwaseem6065@gmail.com

Place of Birth: Lakki Marwat, Khyber Pakhtunkhwa

Citizenship: Pakistani
Date of Birth: April 01, 1985

OBJECTIVE

To seek a career position in a progressive organization which should be a challenging &

demanding, and where I can practice my repertoire and learn new skills.

EDUCATION

09/2015 - Ph.D. (Pharmaceutics), School of Pharmacy, Tongji Medical college,

05/2019 Huazhong University of Science and Technology, Wuhan, China
Dissertation: Synergism of cisplatin-oleanolic acid co-loaded calcium
carbonate nanoparticles on hepatocellular carcinoma cells for enhanced
apoptosis and reduced hepatotoxicity.

02/2010 - M.Phil. (Pharmaceutics), Faculty of Pharmacy, The Islamia University,

03/2013 Bahawalpur, Pakistan.
Dissertation: Formulation and In vitro Evaluation of Sumatriptane Succinate
transdermal patches.

08/2003 - Pharm.D. (Pharmacy), Faculty of Pharmacy, Gomal University Dera Ismail

06/2008 Khan, Pakistan
Major Subjects: Pharmaceutics, Pharmacology, Pharmaceutical Chemistry,
Microbiology, Organic Chemistry, Industrial Pharmacy.

08/2000 - HSSC (Pre-medical), Qurtuba Public School & College, Dera Ismail Khan,
05/2002 Pakistan

08/1998 - SSC (Science), Qurtuba Public School & College, Dera Ismail Khan,
05/2000 Pakistan
SELECTED PUBLICATIONS

1. Khan, M. W., Zhao, P., Khan, A., Raza, F., Raza, S. M., Sarfraz, M & Xiang, G. (2019).
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on
hepatocellular carcinoma cells for enhanced apoptosis and reduced
hepatotoxicity. International Journal of Nanomedicine, 14, 3753-3771.

2. Li, M., Zhao, P., Fan, T., Chen, Y., Zhang, X., He, C., ... & Ma, X. (2019). Biocompatible
co-loading vehicles for delivering both nanoplatin cores and siRNA to treat
hepatocellular carcinoma. International journal of pharmaceutics, 118769.

3. Chen, Y., Chen, C., Zhang, X., He, C., Zhao, P., Li, M., ... & Khan, M. W. (2019).
Platinum complexes of curcumin delivered by dual-responsive polymeric nanoparticles
improve chemotherapeutic efficacy based on the enhanced anti-metastasis activity and
reduce side effects. Acta Pharmaceutica Sinica B.
4. Weijie Li, Ruicong Yan, Yong Liu, Chuanchuan He, Xiaojuan Zhang, Yao Lu,
Muhammad Waseem Khan, Chuanrui Xu, Tan Yang & Guangya Xiang (2019) Co-
delivery of Bmi1 small interfering RNA with ursolic acid by folate receptor-targeted
cationic liposomes enhances anti-tumor activity of ursolic acid invitro and invivo, Drug
Delivery, 26:1, 794-802.

5. Asifullah, K., Zhou, Z., He, W., Gao, K., Khan, M. W., Faisal, R, & Sun, M. (2019).
CXCR4-Receptor Targeted Liposomes for the Treatment of Peritoneal
Fibrosis. Molecular pharmaceutics.

6. Raza, F., Zhu, Y., Chen, L., You, X., Zhang, J., Khan, A, & Ge, L. (2019). Paclitaxel-
loaded pH responsive hydrogel based on self-assembled peptides for tumor
targeting. Biomaterials science .

7. Sarfraz, M., Afzal, A., Yang, T., Gai, Y., Raza, S., Khan, M, & Xiang, G. (2018).
Development of Dual Drug Loaded Nanosized Liposomal Formulation by A
Reengineered Ethanolic Injection Method and Its Pre-Clinical Pharmacokinetic
Studies. Pharmaceutics, 10(3), 151.

8. Komal Siddiqui, Abdul Waris, Habiba Akber, Kinza Munir, Maria Mir, Muhammad
Waseem Khan, Waqar Aman and Fakhar-ud-Din*, “Physicochemical Modifications and
Nano Particulate Strategies for Improved Bioavailability of Poorly Water Soluble Drugs”,
Pharmaceutical Nanotechnology (2017).

9. Sarfraz, M., Afzal, A., Raza, S. M., Bashir, S., Madni, A., Khan, M. W, & Xiang, G.
(2017). Liposomal co-delivered oleanolic acid attenuates doxorubicin-induced multi-
organ toxicity in hepatocellular carcinoma. Oncotarget, 8(29), 47136.

10. Khan, M. W., Nisar-ur-Rahman, Nawaz, A., & Khan, J. A. (2014). Formulation and In
Vitro Evaluation of Sumatriptane Succinate Transdermal Patches. LATIN AMERICAN
 JOURNAL OF PHARMACY, 33(4), 574-578.

11. A pH-Sensitive drug delivery increases tumor accumulation of synergistic

chemotherapy
Muhammad Waseem Khan. Tan Yang, Chenming Zou, Said Hassan, Asif Nawaz,
Mahaman Yacoubou Abdoul Razak, Yan Chen, Wenwen Zhu, Fakhar-Ud-Dom. Xiang
Maa.*. Guangya Xianga,* (Submitted)

RESEARCH FIELDS EXPERIENCE

 Nano Materials

 Tumor Targeting

 Drug Delivery

 Cancer Therapy

RESEARCH TECHNIQUES EXPERIENCE

 Synthesis and characterization of nanoparticles

 Cell and molecular biology assays

 Tumor models

 HPLC and Flow Cytometry

REFERENCES

Prof. Dr. Xiang Guangya

PhD Advisor, School of Pharmacy, Tongji Medical College, HUST, Wuhan, China.
Email: gyxiang1968@hotmail.com; youjiti@mails.tjmu.edu.cn
Phone: 0086-27-83692793 (Cell), 0086-13437294800

Prof. Dr. Nisar Ur Rahman

M.Phil Advisor,
Dean/ faculty of Pharmacy, Margalla Institute of Health Sciences, Rawalpindi, Pakistan.
Email: nisar60@yahoo.com
Phone: 0092-3007334453