Department of Pathology ELM 2

Pathology Tutorial 1 Musculoskeletal Module

Quiz Inflammation & Healing

1. In the battlefield that is acute Inflammation, which of the following cells clear up the
necrotic debris and produce cytokines and growth factors to set the stage for
healing/repair?
a. Macrophages
b. T Lymphocytes
c. Plasma cells
d. Neutrophils
e. B lymphocytes

2. A 7 year old boy developed tonsillitis. On examination, his temperature was 39.5°C,
his tonsils were red, swollen, and covered with pus. Sampling of the pus will lead to
detection of which of the following cells under the microscope?
a. Macrophages
b. T Lymphocytes
c. Plasma cells
d. Neutrophils
e. B lymphocytes

3. A 5 year old child falls from a swing and bumps the back of his head on the ground.
On examination, there were no skin cuts, bruising, or bone fractures. Few hours later,
the area appears swollen. Which of the following contributes most to development of
this swelling?
a. Selectins
b. The complement system
c. Histamine
d. Integrins
e. Cytokines like TNF & IL-1

4. Which of the following is NOT true regarding granulation tissue?

a. It involves budding of new capillaries from pre-existing ones
b. Neutrophils play a central role in its formation
c. It is formed of capillaries, fibroblasts, and extracellular matrix
d. It is driven mainly by TGF-β
e. It is the fore-founder of fibrous tissue

5. What is the mechanical strength of a C-section scar in relation to normal skin?

a. 80%
b. 95%
c. 50%
d. 25%
e. 30%

NG 2021
Department of Pathology ELM 2

Pathology Tutorial 1 Musculoskeletal Module

Quiz Inflammation & Healing

6. A 19 y/o girl complained of nausea, vomiting, and right lower abdominal pain. She
was diagnosed with acute appendicitis and appendicectomy was immediately
performed. The resected appendix was sent to the Pathology lab for examination.
Which of the following cell types would be seen predominantly infiltrating the
appendicular wall under the microscope?
a. Macrophages
b. T Lymphocytes
c. Neutrophils
d. Plasma cells
e. B lymphocytes

7. Which of the following is likely to heal by primary intention?

a. A bone fracture when edges are well approximated
b. A surgical wound
c. A skin wound that requires grafting
d. An infected cut wound
e. Lacerations

8. A 23 year old man fell off his bike and fractured his left clavicle. Which of the
following is expected to be filling the fracture site, two weeks later?
a. Fibrous tissue
b. Granulation tissue
c. A soft callus
d. A hard callus
e. A hematoma

9. If fibrous tissue is seen at the fracture site in the previous case (Q8), two weeks later;
which of the following could be the cause?
a. Poor blood supply
b. Poor alignment
c. Inadequate fixation
d. Infection
e. Any of the above

10. Which of the following is a common systemic effect of inflammation?

a. Decrease in fibrinogen
b. Decrease in erythrocyte sedimentation rate
c. Increase in CRP
d. Hypothermia
e. Decrease in leukocytes

NG 2021