BASIS OF DESIGN SPECIFICATIONS

Micro CLEAN ROOM Technologies M/s. NATCO PHARMA LTD. Pharma Divison
Hyderabad Dehradun. Our Ref 043 R7 Date : 09-10-2017

AHU DETAILS FOR SOLID DOSAGE FORMS PHASE - II

AS PER HEATLOAD SELECTED CAPACITY SUPPLY RETURN / EXHAUST

Selected supply air qty. (Cfm)

Air qty. based on air changes
Diversity factor of Equipment

Actual Equipment Load (KW)

ACH based on selected cfm
Room Dimensions

Room pressure range (Pa)

TERMINAL RAISER

Min No.of Desired ACH

Bleed off air Qty (Cfm)

Equipment Load (KW)

Exhaust air qty. (Cfm)

Relative Humidity (%)
(m) Cooling cap. (TR) SUPPLY / EXHAUST AHU Diffuser Diffuser

Class of Cleanliness

Class of Cleanliness
Return air qty. (Cfm)
Dehumid. air qty. (Cfm)
HEPA WITH 10

Fresh air qty. (Cfm)

Room volume (Ft3)

Selected Reheat KW
Temperature (°C)

EXfitration (Cfm)
Infiltration (Cfm)
Room area (Ft2)
Room area (M2)
FILTER MICRON
AHU TAG NO.

AHU TAG NO.

Room Name

Occupancy
Height (Ft)

As per Bid
False Ceiling Height

Remarks
Reheat KW

CHW manifold size

610x610x150mm -

450x450x150mm -
Cooling cap. (TR)

HW manifold size

450x450mm - 650

275x275mm - 300

750x100mm - 525

750x100mm - 525

450x450mm - 650

450x450mm - 650

275x275mm - 300
(Cfm)
Sl.No

Type

Static pressure
bkw

750 Cfm (FM1)

400 Cfm (FM2)

Reheat (Kw)

(Dia in mm)

(Dia in mm)

Cfm (RD1)
Cfm (SD1)

Cfm (SD2)

Cfm (ED1)

Cfm (ED2)
(mmwgp)

Cfm (R 1)

Cfm (E 1)
Selected
Length

Width

CFM

CFM
Sum

Mon
1 Material Entry 1 3.13 2.20 2.80 6.89 74.09 9.18 680.47 0.54 50 50 1.0 - 567 0.55 1.13 1.13 1.40 1.40 322 567 0 539 28 1 1

(6000 cfm / TSP 160 mm of WC /

(6000 cfm / TSP 160 mm of WC /

40
2 Corridor 11.92 2.20 2.80 26.22 282.17 9.18 2591.45 1.02 30 25 25 1.0 - 2 1080 2.23 3.20 3.20 1.12 1.12 563 1080 378 1113 345 2 2

3 Men Entry 1 2.11 4.82 2.80 10.17 109.43 9.18 1005.02 0.40 20 25 28 1.0 - 419 0.81 1.65 1.65 2.04 2.04 472 472 114 139 447 1 1

16 TR / 17 kW)

15 TR / 5 kW)
Recirculation
AHU-01

AHU-01
22±3°C
4 Quarantine 1 3.88 4.82 2.80 18.70 201.23 9.18 1848.09 0.73 25 28 1.0 - 770 1.49 3.03 3.03 3.75 3.75 867 867 129 0 996 2 2

ISO-8

ISO-8
20

50±5
1483 77

15.64

16.52

50.00

25.00
5364

160
5 Air Lock 1.80 2.20 2.80 3.96 42.61 9.18 391.33 0.55 40 90 90 1.0 - 587 0.32 0.65 0.65 0.80 0.80 185 587 0 539 48 1 1

6 Change Parts 1 4.30 2.55 2.80 10.97 117.98 9.18 1083.56 0.43 20 25 28 1.0 - 451 0.87 1.77 1.77 2.19 2.19 507 507 189 0 696 1 2

7 Cleaned Equipment 1 2.60 5.30 2.80 13.78 148.27 9.18 1361.74 0.54 20 25 28 1.0 - 567 1.10 2.23 2.23 2.77 2.77 640 640 114 0 754 1 2

8 Staging 1 2.30 5.30 2.80 12.19 131.16 9.18 1204.61 0.47 20 25 28 1.0 - 502 0.97 1.98 1.98 2.45 2.45 567 567 0 0 567 1 1
Total 102.88 1106.95 10166.27 4.67 0.00 0.00 2 4943 8.34 15.64 15.64 16.52 16.52 4123 5287 924 2330 3881 1483 0 77 10 0 0 0 12 0 0 0 0

(5000 cfm / TSP

(4000 cfm / TSP

12 TR / 17.5 kW)
210 mm of WC /

210 mm of WC /
12 TR / 12 kW)
Recirculation
1 Granulation 7.60 4.82 4.10 36.63 394.16 13.45 5300.67 2.74 20 25 33 15.00 0.5 7.50 2 2209 5.69 7.69 7.69 4.75 12.25 2954 2954 189 0 3143 5 6
AHU-02

AHU-02
22±3°C
ISO-8

ISO-8
35±5
281 659

10.35

17.02

40.00

25.00
4537

210
2 Blender 3.05 4.82 2.80 14.70 158.18 9.18 1452.75 0.75 20 25 38 5.00 0.7 3.50 1 605 2.12 2.66 2.66 1.27 4.77 924 924 189 0 1113 2 3

Total 51.33 552.34 6753.42 3.49 20.00 11.00 3 2814 7.81 10.35 10.35 6.02 17.02 3878 3878 378 0 4256 281 0 659 7 0 0 0 9 0 0 0 0

210 mm of WC / 8
8.5 TR / 12.5 kW)
(3100 cfm / TSP

(3000 cfm / TSP

210 mm of WC /
Recirculation

TR / 5 kW)
AHU-03

AHU-03
22±3°C
ISO-8

ISO-8
35±5

1 FBC 7.45 5.30 4.50 39.49 424.86 14.76 6270.91 3.24 20 25 25 10.00 0.7 7.00 2 2613 6.04 8.34 8.34 5.37 12.37 2218 2613 189 0 2802 261 450 5 6

12.37

32.00

25.00
3063

8.34
210
Total 39.49 424.86 6270.91 3.24 10.00 7.00 2 2613 6.04 8.34 8.34 5.37 12.37 2218 2613 189 0 2802 261 0 450 5 0 0 0 6 0 0 0 0

1 Material Entry 2 3.10 2.20 2.80 6.82 73.38 9.18 673.95 0.53 40 50 50 1.0 - 562 0.62 1.36 1.36 2.08 2.08 462 562 0 539 23 1 1

(5000 cfm / TSP 160 mm

(5000 cfm / TSP 160 mm

of WC / 14 TR / 17.5 kW)

of WC / 13 TR / 5 kW)
2 Corridor 12.20 2.20 2.80 26.84 288.80 9.18 2652.32 1.04 30 25 29 2.00 1.0 2.00 1105 2.86 4.45 4.45 3.25 5.25 1289 1289 378 810 857 2 2
Recirculation
AHU-04

AHU-04
22±3°C

3 Quarantine 2 2.30 5.25 2.80 12.08 129.93 9.18 1193.25 0.47 20 25 28 1.0 - 497 0.96 1.95 1.95 2.41 2.41 558 558 189 0 747 1 2
ISO-8

ISO-8
50±5

1372 140

13.58

17.07

50.00

25.00
4447

160
4 Air Lock 1.50 2.20 2.80 3.30 35.51 9.18 326.11 0.56 40 110 110 1.0 - 598 0.62 1.29 1.29 1.71 1.71 403 598 0 539 59 1 1

5 Change Parts 2 3.25 4.93 2.80 16.02 172.40 9.18 1583.34 0.62 20 25 28 1.0 - 660 1.28 2.59 2.59 3.21 3.21 743 743 114 0 857 1 2

6 Men Entry 2 2.45 4.93 2.80 12.08 129.96 9.18 1193.60 0.47 20 25 28 1.0 - 497 0.96 1.94 1.94 2.41 2.41 558 558 114 139 533 1 1
Total 77.14 829.98 7622.57 3.70 2.00 2.00 0 3919 7.30 13.58 13.58 15.07 17.07 4013 4307 795 2027 3075 1372 0 140 7 0 0 0 9 0 0 0 0

(6000 cfm / TSP

(4000 cfm / TSP

210 mm of WC /

210 mm of WC /
11 TR / 19 kW)

10 TR / 12 kW)
Recirculation

1 Sieving and Blending 5.35 5.25 2.80 28.09 302.22 9.18 2775.60 1.43 20 25 39 10.00 0.7 7.00 2 1157 3.84 4.53 4.53 1.73 8.73 1822 1822 212 0 2034 3 5
AHU-05

AHU-05
22±3°C
ISO-8

ISO-8
35±5

232 633

17.40

40.00

25.00
4239

8.99
210
2 Roll Compactor 4.30 5.25 3.50 22.58 242.91 11.48 2788.57 1.44 20 25 38 10.00 0.7 7.00 2 1162 3.77 4.46 4.46 1.67 8.67 1784 1784 189 0 1973 3 5

Total 50.66 545.13 5564.17 2.87 20.00 14.00 4 2318 7.61 8.99 8.99 3.40 17.40 3606 3606 401 0 4007 232 0 633 6 0 0 0 10 0 0 0 0

(4000 cfm / TSP

(3000 cfm / TSP

210 mm of WC /

210 mm of WC /
1 Men Entry 3 3.10 2.40 2.80 7.44 80.05 9.18 735.22 0.38 20 25 25 1.0 - 306 0.37 0.72 0.72 1.00 1.00 277 306 0 253 53 1 1

8 TR / 11 kW)
Recirculation

5 TR / 3 kW)
AHU-06

AHU-06
22±3°C
ISO-8

ISO-8
35±5

2 Material Entry 3 3.10 2.42 2.80 7.50 80.72 9.18 741.35 0.38 20 25 25 1.0 - 309 0.37 0.72 0.72 1.00 1.00 277 309 0 253 56 346 68 1 1

10.66

32.00

25.00
3529

7.89
210
3 Spray Dryer 7.85 4.93 5.00 38.70 416.42 16.40 6829.25 3.53 10 25 25 5.00 1.0 5.00 2 2846 4.86 6.45 6.45 3.66 8.66 2435 2846 228 0 3074 5 6

Total 53.64 577.19 8305.81 4.29 5.00 5.00 2 3461 5.60 7.89 7.89 5.66 10.66 2989 3461 228 506 3183 346 0 68 7 0 0 0 8 0 0 0 0

Page 1 of 5
 BASIS OF DESIGN SPECIFICATIONS
Micro CLEAN ROOM Technologies M/s. NATCO PHARMA LTD. Pharma Divison
Hyderabad Dehradun. Our Ref 043 R7 Date : 09-10-2017

AHU DETAILS FOR SOLID DOSAGE FORMS PHASE - II

AS PER HEATLOAD SELECTED CAPACITY SUPPLY RETURN / EXHAUST

Selected supply air qty. (Cfm)

Air qty. based on air changes
Diversity factor of Equipment

Actual Equipment Load (KW)

ACH based on selected cfm
Room Dimensions

Room pressure range (Pa)

TERMINAL RAISER

Min No.of Desired ACH

Bleed off air Qty (Cfm)

Equipment Load (KW)

Exhaust air qty. (Cfm)

Relative Humidity (%)
(m) Cooling cap. (TR) SUPPLY / EXHAUST AHU Diffuser Diffuser

Class of Cleanliness

Class of Cleanliness
Return air qty. (Cfm)
Dehumid. air qty. (Cfm)
HEPA WITH 10

Fresh air qty. (Cfm)

Room volume (Ft3)

Selected Reheat KW
Temperature (°C)

EXfitration (Cfm)
Infiltration (Cfm)
Room area (Ft2)
Room area (M2)
FILTER MICRON
AHU TAG NO.

AHU TAG NO.

Room Name

Occupancy
Height (Ft)

As per Bid
False Ceiling Height

Remarks
Reheat KW

CHW manifold size

610x610x150mm -

450x450x150mm -
Cooling cap. (TR)

HW manifold size

450x450mm - 650

275x275mm - 300

750x100mm - 525

750x100mm - 525

450x450mm - 650

450x450mm - 650

275x275mm - 300
(Cfm)
Sl.No

Type

Static pressure
bkw

750 Cfm (FM1)

400 Cfm (FM2)

Reheat (Kw)

(Dia in mm)

(Dia in mm)

Cfm (RD1)
Cfm (SD1)

Cfm (SD2)

Cfm (ED1)

Cfm (ED2)
(mmwgp)

Cfm (R 1)

Cfm (E 1)
Selected
Length

Width

CFM

CFM
Sum

Mon

(6000 cfm / TSP 160 mm of WC / 15 TR /

(6000 cfm / TSP 160 mm of WC / 15 TR /

1 Material Entry 4 2.25 2.20 2.80 4.95 53.26 9.18 489.16 0.54 40 70 70 1.0 - 571 0.40 0.81 0.81 1.00 1.00 232 571 0 539 32 1 1

2 Corridor 7.00 2.20 2.80 15.40 165.70 9.18 1521.83 0.84 30 35 35 1.0 - 2 888 1.37 1.88 1.88 0.48 0.48 315 888 378 1236 30 2 2

3 IPQA 1.84 2.80 2.80 5.15 55.44 9.18 509.12 0.20 20 25 25 1.0 - 3 212 0.63 0.78 0.78 0.09 0.09 136 212 114 0 326 1 1

Recirculation
4 Change Parts 3 1.98 4.82 2.80 9.54 102.69 9.18 943.10 0.37 20 25 28 1.0 - 393 0.76 1.54 1.54 1.91 1.91 442 442 114 0 556 1 1
AHU-07

AHU-07
22±3°C

13 kW)
ISO-8

ISO-8

5 kW)
50±5
5 Men Entry 4 2.33 4.82 2.80 11.23 120.84 9.18 1109.81 0.44 20 25 28 1.0 - 462 0.89 1.08 1.08 2.45 2.45 520 520 114 139 495 2144 97 1 1

12.91

12.92

50.00

25.00
5167

160
6 Wash 2.88 4.82 2.80 13.88 149.37 9.18 1371.78 0.54 20 25 25 1.0 - 1 572 1.18 1.70 1.70 0.62 0.62 300 572 129 0 701 1 2

7 Air Lock 1.65 2.20 2.80 3.63 39.06 9.18 358.72 0.54 40 95 95 1.0 - 568 0.30 0.60 0.60 0.75 0.75 172 568 0 539 29 1 1

8 Quarantine 3 2.90 5.65 2.80 16.39 176.30 9.18 1619.16 0.64 20 25 28 1.0 - 675 1.31 2.65 2.65 3.30 3.30 760 760 129 0 889 1 2

9 Quarantine 4 2.05 5.65 2.80 11.58 124.63 9.18 1144.58 0.45 20 25 28 1.0 - 477 0.92 1.87 1.87 2.32 2.32 537 537 129 0 666 1 2
Total 91.76 987.29 9067.24 4.55 0.00 0.00 6 4817 7.76 12.91 12.91 12.92 12.92 3414 5069 1107 2453 3023 2144 701 97 10 0 0 0 11 2 0 0 0

(2050 cfm / TSP

(2000 cfm / TSP

160 mm of WC /

160 mm of WC /
Recirculation

5 TR / 6 kW)

5 TR / 6 kW)
4.30 4.82 3.50 20.73 223.01 11.48
AHU-08

AHU-08
22±3°C
ISO-8

ISO-8
50±5
1 Capsule Filling 3022.65 1.56 20 25 35 10.00 0.7 7.00 3 1259 3.72 4.33 4.33 1.33 1.33 1775 1775 129 0 1904 126 255 3 4

2030

4.33

1.33
160

25

20
1.95 1.92 3.50 3.74 40.29 11.48

Total 24.47 263.30 3022.65 1.56 10.00 7.00 3 1259 3.72 4.33 4.33 1.33 1.33 1775 1775 129 0 1904 126 0 255 3 0 0 0 4 0 0 0 0

(3000 cfm / TSP 160

(3000 cfm / TSP 160

mm of WC (FLP) / 5

mm of WC (FLP) / 5
Recirculation

TR / 9 kW)

TR / 6 kW)
AHU-09

AHU-09
22±3°C
ISO-8

ISO-8
50±5

1 Tablet Coating 1 4.25 5.65 2.80 24.01 258.37 9.18 2372.91 0.93 20 25 43 10.00 0.7 7.00 2 989 3.44 4.03 4.03 1.47 8.47 1709 1709 189 0 1898 99 288 3 4

25.00

20.00
1997

4.03

8.47
160
Total 24.01 258.37 2372.91 0.93 10.00 7.00 2 989 3.44 4.03 4.03 1.47 8.47 1709 1709 189 0 1898 99 0 288 3 0 0 0 4 0 0 0 0

(2000 cfm / TSP

(2000 cfm / TSP

210 mm of WC /

210 mm of WC /
Recirculation

5 TR / 7 kW)

4 TR / 3 kW)
AHU-10

AHU-10
22±3°C
ISO-8

ISO-8
35±5

1 Compression 1 4.25 5.65 4.50 24.01 258.37 14.76 3813.61 1.97 20 25 26 5.00 1.0 5.00 2 1589 3.53 4.36 4.36 1.86 6.86 1631 1631 189 0 1820 159 348 3 4

25.00

20.00
1979

4.36

6.86
210
Total 24.01 258.37 3813.61 1.97 5.00 5.00 2 1589 3.53 4.36 4.36 1.86 6.86 1631 1631 189 0 1820 159 0 348 3 0 0 0 4 0 0 0 0

(6000 cfm / TSP 160 mm of WC / 20 TR /

(8000 cfm / TSP 160 mm of WC / 20 TR /

1 Material Entry 5 2.60 2.20 2.80 5.72 61.55 9.18 565.25 0.53 40 60 60 1.0 - 565 0.57 1.09 1.09 1.18 1.18 271 565 0 539 26 1 1

2 Corridor 9.55 2.20 2.80 21.01 226.07 9.18 2076.20 0.98 30 30 30 1.0 - 2 1038 2.22 3.20 3.20 0.98 0.98 475 1038 378 1302 114 2 2

3 Quarantine 5 5.10 4.45 2.80 22.70 244.20 9.18 2242.72 0.88 20 25 27 1.0 - 934 2.24 4.32 4.32 4.63 4.63 1003 1003 189 0 1192 2 3
Recirculation

4 Change Parts 4 2.45 4.45 2.80 10.90 117.31 9.18 1077.38 0.42 20 25 29 1.0 - 449 1.08 2.08 2.08 2.23 2.23 515 515 189 0 704 1 2

16.5 kW)
AHU-11

AHU-11
22±3°C
ISO-8

ISO-8

5 kW)
50±5

5 Wash 2.55 4.45 2.80 11.35 122.10 9.18 1121.36 0.44 20 25 25 1.0 - 1 467 1.19 1.74 1.74 0.56 0.56 260 467 189 0 2298 656 425 1 2

19.27

16.08

50.00

32.00
5987

160
6 Quarantine 6 3.35 4.45 2.80 14.91 160.40 9.18 1473.16 0.58 20 25 27 1.0 - 614 1.47 2.84 2.84 3.04 3.04 659 659 129 0 788 2 2

7 Air Lock 1.50 2.20 2.80 3.30 35.51 9.18 326.11 0.51 40 100 100 1.0 - 544 0.33 0.64 0.64 0.69 0.69 158 544 0 539 5 1 1

8 Men Entry 5 2.45 5.38 2.80 13.18 141.83 9.18 1302.54 0.51 20 25 27 1.0 - 543 1.30 2.50 2.50 2.68 2.68 581 581 114 139 556 1 1

9 IPQC 2.05 2.25 2.80 4.61 49.63 9.18 455.81 0.18 20 25 25 1.0 - 3 190 0.67 0.86 0.86 0.09 0.09 130 190 114 0 304 1 1
Total 107.68 1158.59 10640.53 5.05 0.00 0.00 6 5344 11.07 19.27 19.27 16.08 16.08 4052 5562 1302 2519 3689 2298 656 425 12 0 0 0 13 2 0 0 0

(3000 cfm / TSP

(2000 cfm / TSP

160 mm of WC /

160 mm of WC /
Recirculation

6 TR / 9 kW)

6 TR / 6 kW)
AHU-12

AHU-12
22±3°C
ISO-8

ISO-8
50±5

1 Tablet Coating 2 4.40 5.38 2.80 23.67 254.71 9.18 2339.26 0.92 20 25 44 10.00 0.7 7.00 2 975 3.43 4.01 4.01 1.44 8.44 1704 1704 189 0 1893 97 286 3 4

25.00

20.00
1990

4.01

8.44
160
Total 23.67 254.71 2339.26 0.92 10.00 7.00 2 975 3.43 4.01 4.01 1.44 8.44 1704 1704 189 0 1893 97 0 286 3 0 0 0 4 0 0 0 0

Page 2 of 5
 BASIS OF DESIGN SPECIFICATIONS
Micro CLEAN ROOM Technologies M/s. NATCO PHARMA LTD. Pharma Divison
Hyderabad Dehradun. Our Ref 043 R7 Date : 09-10-2017

AHU DETAILS FOR SOLID DOSAGE FORMS PHASE - II

AS PER HEATLOAD SELECTED CAPACITY SUPPLY RETURN / EXHAUST

Selected supply air qty. (Cfm)

Air qty. based on air changes
Diversity factor of Equipment

Actual Equipment Load (KW)

ACH based on selected cfm
Room Dimensions

Room pressure range (Pa)

TERMINAL RAISER

Min No.of Desired ACH

Bleed off air Qty (Cfm)

Equipment Load (KW)

Exhaust air qty. (Cfm)

Relative Humidity (%)
(m) Cooling cap. (TR) SUPPLY / EXHAUST AHU Diffuser Diffuser

Class of Cleanliness

Class of Cleanliness
Return air qty. (Cfm)
Dehumid. air qty. (Cfm)
HEPA WITH 10

Fresh air qty. (Cfm)

Room volume (Ft3)

Selected Reheat KW
Temperature (°C)

EXfitration (Cfm)
Infiltration (Cfm)
Room area (Ft2)
Room area (M2)
FILTER MICRON
AHU TAG NO.

AHU TAG NO.

Room Name

Occupancy
Height (Ft)

As per Bid
False Ceiling Height

Remarks
Reheat KW

CHW manifold size

610x610x150mm -

450x450x150mm -
Cooling cap. (TR)

HW manifold size

450x450mm - 650

275x275mm - 300

750x100mm - 525

750x100mm - 525

450x450mm - 650

450x450mm - 650

275x275mm - 300
(Cfm)
Sl.No

Type

Static pressure
bkw

750 Cfm (FM1)

400 Cfm (FM2)

Reheat (Kw)

(Dia in mm)

(Dia in mm)

Cfm (RD1)
Cfm (SD1)

Cfm (SD2)

Cfm (ED1)

Cfm (ED2)
(mmwgp)

Cfm (R 1)

Cfm (E 1)
Selected
Length

Width

CFM

CFM
Sum

Mon

(2000 cfm / TSP

(2000 cfm / TSP

210 mm of WC /

210 mm of WC /
Recirculation

6 TR / 7 kW)

6 TR / 3 kW)
AHU-13

AHU-13
22±3°C
ISO-8

ISO-8
35±5
1 Tablet Compression 2 4.45 5.38 4.50 23.94 257.61 14.76 3802.25 1.96 20 25 26 5.00 1.0 5.00 2 1584 3.52 4.35 4.35 1.85 6.85 1629 1629 189 0 1818 158 347 3 4

25.00

20.00
1976

4.35

6.85
210
Total 23.94 257.61 3802.25 1.96 5.00 5.00 2 1584 3.52 4.35 4.35 1.85 6.85 1629 1629 189 0 1818 158 0 347 3 0 0 0 4 0 0 0 0

(4000 cfm / TSP 210 mm of

(5000 cfm / TSP 210 mm of

1 Men Entry 6 2.56 2.50 2.80 6.40 68.86 9.18 632.45 0.33 25 25 25 1.0 - 264 0.32 0.61 0.61 0.85 0.85 236 264 0 253 11 1 1

WC / 9 TR / 12 kW)

WC / 8 TR / 6 kW)
2 Material Entry 6 2.56 3.00 2.80 7.68 82.64 9.18 758.94 0.55 25 35 35 1.0 - 443 0.38 0.72 0.72 1.01 1.01 283 443 0 420 23 1 1

Recirculation
AHU-14

AHU-14
22±3°C
ISO-8

ISO-8
35±5
4.30 0.93 3.20 4.00 43.03 10.50 444 74

11.56

40.00

25.00
3742

8.73
210
3 Primary Packing - Bottle 6.75 4.66 3.20 31.46 338.46 10.50 6499.42 3.36 15 25 27 10.00 0.7 7.00 6 2708 6.29 7.40 7.40 2.70 9.70 2962 2962 303 0 3265 4 6

4.01 5.51 3.20 22.10 237.74 10.50

Total 18.08 194.53 7890.80 4.23 10.00 7.00 6 3414 6.99 8.73 8.73 4.56 11.56 3481 3668 303 673 3298 444 0 74 6 0 0 0 8 0 0 0 0

(3000 cfm / TSP

(3000 cfm / TSP

210 mm of WC /

210 mm of WC /
1 Men Entry 9 2.55 2.45 2.80 6.25 67.22 9.18 617.38 0.32 20 25 25 1.0 - 257 0.31 0.59 0.59 0.83 0.83 232 257 0 253 4 1 1

7 TR / 11 kW)
Recirculation

6 TR / 5 kW)
AHU-15

AHU-15
22±3°C
ISO-8

ISO-8
35±5
2 Material Entry 9 2.50 2.45 2.80 6.13 65.91 9.18 605.27 0.50 20 40 40 1.0 - 404 0.30 0.57 0.57 0.80 0.80 225 404 0 400 4 383 33 1 1

10.53

25.00

25.00
2997

6.64
210
3 Blister Packing 6.77 5.00 3.20 33.85 364.23 10.50 3822.92 1.97 10 25 36 7.50 1.0 7.50 6 1593 4.88 5.48 5.48 1.40 8.90 2303 2303 303 0 2606 4 5

Total 46.22 497.35 5045.56 2.79 7.50 7.50 6 2254 5.49 6.64 6.64 3.03 10.53 2760 2964 303 653 2614 383 0 33 6 0 0 0 7 0 0 0 0

47.32 1.70 2.80 80.44 865.58 9.18

2.32 25.40 2.80 58.93 634.07 9.18

1 Corridor 40.06 1.89 2.80 75.71 814.68 9.18 32248.61 3.17 5 10 10 - 5375 8.67 8.67 0.00 3558 5375 3648 1184 7839 15 16

(14000 cfm / TSP 100 mm of WC / 31 TR / 15 kW)

(14000 cfm / TSP 100 mm of WC / 31 TR / 15 kW)

2.00 25.40 2.80 50.80 546.61 9.18

2.38 25.40 2.80 60.45 650.46 9.18

2 Unscrambler 3.81 3.91 2.80 14.90 160.29 9.18 1472.13 0.36 10 25 25 - 613 0.54 0.54 0.00 169 613 0 81 532 2 2

3 Spare - 1 4.65 7.85 2.80 36.50 392.77 9.18 3607.17 0.53 0 15 15 - 902 1.18 1.18 0.00 470 902 134 0 1036 2 2
Recirculation
Un classified

Un classified
AHU-16

AHU-16
4 Spare - 2 4.65 7.85 2.80 36.50 392.77 9.18 3607.17 0.53 0
22±3°C

15 15 - 902 1.18 1.18 0.00 470 902 134 0 1036 2 2

NA

808 3552

13976

17.55
100

50
5 Wash 4.30 2.65 2.80 11.40 122.61 9.18 1126.05 0.17 0 15 15 - 282 0.30 0.30 0.00 110 282 134 0 416 1 1

6 Cleaned Equipment 2 4.03 2.70 2.80 10.88 117.08 9.18 1075.26 0.16 15 15 15 - 269 0.29 0.29 0.00 105 269 0 189 80 1 1

7 Production Office 4.03 2.45 2.80 9.87 106.24 9.18 975.70 0.10 0 10 10 - 4 163 0.60 0.60 0.00 161 163 134 0 297 1 1

9.42 6.06 2.80 57.09 614.24 9.18

8 Secondary Packing 1 5857.12 0.58 0 10 10 - 10 976 2.42 2.42 0.00 783 976 134 0 1110 3 3
2.35 0.93 2.80 2.19 23.52 9.18

9 Secondary Packing 2 9.45 4.23 2.80 39.97 430.11 9.18 3950.17 0.39 0 10 10 - 10 658 1.94 1.94 0.00 591 658 134 0 792 3 3

10 Punch Room 2.05 3.03 2.80 6.21 66.84 9.18 613.82 0.09 0 15 15 - 153 0.17 0.17 0.00 62 153 81 0 234 1 1

11 Scrap 4.24 1.87 2.80 7.93 85.31 9.18 783.52 0.08 0 10 10 - 131 0.26 0.26 0.00 113 131 81 0 212 1 1

Total 559.77 6023.16 55316.73 6.15 0.00 0.00 24 10423 17.55 0.00 17.55 0.00 0.00 6592 10423 4614 1454 13168 808 416 3552 3 0 29 0 3 0 29 1 0

(2000 cfm / TSP

(2000 cfm / TSP

210 mm of WC /

210 mm of WC /
5 TR / 4.5 kW)
1 Men Entry 7 2.65 2.15 2.80 5.70 61.31 9.18 563.03 0.41 20 35 35 1.0 - 328 0.69 1.10 1.10 0.81 0.81 221 328 0 278 50 1 1
Recirculation

2 TR / 1 kW)
AHU-17

AHU-17
22±3°C
ISO-8

ISO-8
35±5

2 Material Entry 7 1.85 2.15 2.80 3.98 42.80 9.18 393.06 0.37 20 45 45 1.0 - 295 0.48 0.77 0.77 0.56 0.56 153 295 0 278 17 455 38 1 1

25.00

20.00
1433

4.86

4.34
210
3 Sampling 3.05 4.10 2.80 12.51 134.55 9.18 1235.74 0.64 10 25 37 2.00 1.0 2.00 2 515 2.30 2.99 2.99 0.97 2.97 772 772 278 139 911 1 2

Total 22.18 238.66 2191.82 1.41 2.00 2.00 2 1138 3.47 4.86 4.86 2.34 4.34 1146 1395 278 695 978 455 0 38 3 0 0 0 4 0 0 0 0

Page 3 of 5
 BASIS OF DESIGN SPECIFICATIONS
Micro CLEAN ROOM Technologies M/s. NATCO PHARMA LTD. Pharma Divison
Hyderabad Dehradun. Our Ref 043 R7 Date : 09-10-2017

AHU DETAILS FOR SOLID DOSAGE FORMS PHASE - II

AS PER HEATLOAD SELECTED CAPACITY SUPPLY RETURN / EXHAUST

Selected supply air qty. (Cfm)

Air qty. based on air changes
Diversity factor of Equipment

Actual Equipment Load (KW)

ACH based on selected cfm
Room Dimensions

Room pressure range (Pa)

TERMINAL RAISER

Min No.of Desired ACH

Bleed off air Qty (Cfm)

Equipment Load (KW)

Exhaust air qty. (Cfm)

Relative Humidity (%)
(m) Cooling cap. (TR) SUPPLY / EXHAUST AHU Diffuser Diffuser

Class of Cleanliness

Class of Cleanliness
Return air qty. (Cfm)
Dehumid. air qty. (Cfm)
HEPA WITH 10

Fresh air qty. (Cfm)

Room volume (Ft3)

Selected Reheat KW
Temperature (°C)

EXfitration (Cfm)
Infiltration (Cfm)
Room area (Ft2)
Room area (M2)
FILTER MICRON
AHU TAG NO.

AHU TAG NO.

Room Name

Occupancy
Height (Ft)

As per Bid
False Ceiling Height

Remarks
Reheat KW

CHW manifold size

610x610x150mm -

450x450x150mm -
Cooling cap. (TR)

HW manifold size

450x450mm - 650

275x275mm - 300

750x100mm - 525

750x100mm - 525

450x450mm - 650

450x450mm - 650

275x275mm - 300
(Cfm)
Sl.No

Type

Static pressure
bkw

750 Cfm (FM1)

400 Cfm (FM2)

Reheat (Kw)

(Dia in mm)

(Dia in mm)

Cfm (RD1)
Cfm (SD1)

Cfm (SD2)

Cfm (ED1)

Cfm (ED2)
(mmwgp)

Cfm (R 1)

Cfm (E 1)
Selected
Length

Width

CFM

CFM
Sum

Mon

(3000 cfm / TSP 210

(3000 cfm / TSP 210

mm of WC / 2 TR / 2
1 Men Entry 8 2.45 2.15 2.80 5.27 56.68 9.18 520.53 0.38 20 35 35 1.0 - 304 0.76 1.20 1.20 0.76 0.76 206 304 0 278 26 1 1

mm of WC / 10 TR /
Recirculation
2 Material Entry 8 2.65 2.15 2.80 5.70 61.31 9.18 563.03 0.41 20 35 35 1.0 - 328 0.82 1.30 1.30 0.82 0.82 224 328 0 278 50 1 1
AHU-18

AHU-18
7.5 kW)
22±3°C
ISO-8

ISO-8
35±5

kW)
886 106

40.00

20.00
2378

9.59

7.30
210
3 Tool Wash 2.15 4.10 2.80 8.82 94.85 9.18 871.10 0.45 0 25 25 1.0 - 1 363 1.33 1.83 1.83 0.44 0.44 226 363 278 0 641 1 2

4 Dispensing 4.60 4.10 2.80 18.86 202.93 9.18 1863.74 0.96 10 25 41 3.00 1.0 3.00 2 777 3.81 5.26 5.26 2.28 5.28 1277 1277 278 139 1416 2 3

Total 38.64 415.77 3818.40 2.20 3.00 3.00 3 1772 6.72 9.59 9.59 4.30 7.30 1933 2272 556 695 1492 886 641 106 5 0 0 0 5 2 0 0 0

4.42 6.59 4.50 29.13 313.42 14.76

14.60 8.50 4.50 124.10 1335.32 14.76

1 RM Stores 11.19 1.55 4.50 17.34 186.63 14.76 32405.98 3.19 0 10 10 5.00 1.0 5.00 3 5401 7.82 7.82 5.00 3209 5401 584 0 5985 10 10

(10000 cfm / TSP 100 mm of WC / 16 TR / 6 kW)

(10000 cfm / TSP 100 mm of WC / 16 TR / 6 kW)

10.10 2.53 4.50 25.55 274.95 14.76

1.98 4.00 4.50 7.92 85.22 14.76

2 Air Lock 4.39 2.50 2.80 10.98 118.09 9.18 1084.55 0.11 0 10 10 - 181 0.30 0.30 0.00 86 181 0 0 181 1 1

Recirculation
3 Air Lock 4.39 2.65 2.80 11.63 125.18 9.18 1149.62 0.11 0 10 10 - 192 0.41 0.41 0.00 112 192 0 0 192 1 1
Un classified

Un classified
AHU-19

AHU-19
22±3°C

NA
4 Air Lock 2.30 6.39 2.80 14.70 158.14 9.18 1452.36 0.14 0 10 10 - 242 0.43 0.43 0.00 133 242 114 0 356 706 1518 1 1

10.73
8580

100

40
5 Decartoning 2.06 4.10 2.80 8.45 90.88 9.18 834.63 0.08 0 10 10 - 1 139 0.29 0.29 0.00 84 139 0 0 139 1 1

6 Scrap 3.34 1.50 2.80 5.01 53.91 9.18 495.09 0.05 0 10 10 - 83 0.16 0.17 0.00 39 83 0 0 83 1 1

7 Air lock 3.27 3.30 2.80 10.79 116.11 9.18 1066.36 0.10 0 10 10 - 1 178 0.34 0.34 0.00 103 178 0 0 178 1 1

8 Change Room 3.27 3.40 2.80 11.12 119.63 9.18 1098.68 0.11 0 10 10 - 183 0.26 0.26 0.00 86 183 0 0 183 1 1

9 Air Lock 2.25 3.36 2.80 7.56 81.35 9.18 747.08 0.07 0 10 10 - 125 0.24 0.24 0.00 60 125 114 0 239 1 1

10 Air Lock 4.00 2.50 2.80 10.00 107.60 9.18 988.20 0.10 0 10 10 - 165 0.23 0.23 0.00 76 165 0 0 165 1 1

11 Air Lock 4.00 2.65 2.80 10.60 114.06 9.18 1047.49 0.10 0 10 10 - 175 0.24 0.24 0.00 83 175 0 0 175 1 1

Total 304.88 3280.46 42370.04 4.17 5.00 5.00 5 7062 10.72 0.00 10.73 0.00 5.00 4071 7062 812 0 7874 706 0 1518 0 0 20 0 0 0 20 0 0

(6000 cfm / TSP

(8000 cfm / TSP

100 mm of WC /

100 mm of WC /
10 TR / 5 kW)

10 TR / 1 kW)
AHU-20 (First

AHU-20 (First
Recirculation
Un classified

Un classified
22±3°C
Floor)

Floor)
NA

1 Finished Goods stores 20.98 9.77 4.50 204.91 2204.82 14.76 32543.12 5.12 20 10 10 5.00 1.0 5.00 3 5424 8.29 8.29 5.00 3481 5424 5424 542 542 9 9

32.00
5966

8.29
100
Total 204.91 2204.82 32543.12 5.12 5.00 5.00 3 5424 8.29 0.00 8.29 0.00 5.00 3481 5424 0 0 5424 542 0 542 0 0 9 0 0 0 9 0 0

100 mm of WC / 14

100 mm of WC / 14
(10000 cfm / TSP

(12000 cfm / TSP

1 Staging 6.87 6.35 3.00 43.61 469.25 9.84 4617.44 0.45 0 10 10 1.0 - 1 770 1.31 1.31 0.00 526 770 770 2 2
AHU-21 (First

AHU-21 (First
Recirculation
Un classified

Un classified
TR / 5 kW)

TR / 5 kW)
22±3°C

Primary Component
Floor)

Floor)
2 31.06 9.92 4.00 308.12 3315.32 13.12 43496.99 4.28 0 10 10 5.00 1.0 5.00 3 7249 11.10 11.00 5.00 4628 7249 7249 12 12
NA

828 828

12.95

40.00
Stores

9118

210
3 Rejected Material Stores 4.26 3.50 3.00 14.91 160.43 9.84 1578.65 0.16 0 10 10 1.0 - 1 263 0.64 0.64 0.00 271 271 271 1 1

Total 366.64 3945.00 49693.08 4.89 5.00 5.00 5 8282 13.05 0.00 12.95 0.00 5.00 5425 8290 0 0 8290 828 0 828 0 0 15 0 0 0 15 0 0

(10000 cfm / TSP 100 mm of WC / 14.5

(10000 cfm / TSP 100 mm of WC / 16

1 Office 4.65 3.00 2.80 13.94 149.94 9.18 1377.05 0.14 0 10 12 1.0 - 4 230 0.83 0.83 0.00 278 278 278 1 1

2 Change Room 3.00 3.90 2.80 11.70 125.89 9.18 1156.19 0.11 0 10 10 1.0 - 193 0.42 0.42 0.00 191 193 193 1 1
AHU-22 (First Floor)

AHU-22 (First Floor)

Recirculation
Un classified

Un classified
3 Capsule Storage 3.68 9.92 2.80 36.51 392.80 9.18 3607.48 0.71 0 20 20 1.0 - 1202 1.31 1.31 0.00 481 1202 1202 2 2

TR / 5 kW)

TR / 4 kW)
22±3°C

NA

1019 1019

11258

14.24
100
2.49 3.36 2.80 8.37 90.02 9.18

40
4 Corridor 6.37 2.00 2.80 12.74 137.08 9.18 8753.19 0.86 0 10 10 1.0 - 1459 2.28 2.28 0.00 921 1459 1459 4 3

2.48 27.21 2.80 67.47 725.99 9.18

5 Packing Material Stores 9.47 31.92 4.00 302.08 3250.33 13.12 42644.36 4.20 0 10 10 5.00 1.0 5.00 3 7107 9.40 9.40 5.00 3993 7107 7107 12 12

Total 452.79 4872.06 57538.27 6.02 5.00 5.00 7 10191 14.24 0.00 14.24 0.00 5.00 5864 10239 0 0 10239 1019 0 1019 0 0 20 0 0 0 19 0 0

Page 4 of 5
 BASIS OF DESIGN SPECIFICATIONS
Micro CLEAN ROOM Technologies M/s. NATCO PHARMA LTD. Pharma Divison
Hyderabad Dehradun. Our Ref 043 R7 Date : 09-10-2017

AHU DETAILS FOR SOLID DOSAGE FORMS PHASE - II

AS PER HEATLOAD SELECTED CAPACITY SUPPLY RETURN / EXHAUST

Selected supply air qty. (Cfm)

Air qty. based on air changes
Diversity factor of Equipment

Actual Equipment Load (KW)

ACH based on selected cfm
Room Dimensions

Room pressure range (Pa)

TERMINAL RAISER

Min No.of Desired ACH

Bleed off air Qty (Cfm)

Equipment Load (KW)

Exhaust air qty. (Cfm)

Relative Humidity (%)
(m) Cooling cap. (TR) SUPPLY / EXHAUST AHU Diffuser Diffuser

Class of Cleanliness

Class of Cleanliness
Return air qty. (Cfm)
Dehumid. air qty. (Cfm)
HEPA WITH 10

Fresh air qty. (Cfm)

Room volume (Ft3)

Selected Reheat KW
Temperature (°C)

EXfitration (Cfm)
Infiltration (Cfm)
Room area (Ft2)
Room area (M2)
FILTER MICRON
AHU TAG NO.

AHU TAG NO.

Room Name

Occupancy
Height (Ft)

As per Bid
False Ceiling Height

Remarks
Reheat KW

CHW manifold size

610x610x150mm -

450x450x150mm -
Cooling cap. (TR)

HW manifold size

450x450mm - 650

275x275mm - 300

750x100mm - 525

750x100mm - 525

450x450mm - 650

450x450mm - 650

275x275mm - 300
(Cfm)
Sl.No

Type

Static pressure
bkw

750 Cfm (FM1)

400 Cfm (FM2)

Reheat (Kw)

(Dia in mm)

(Dia in mm)

Cfm (RD1)
Cfm (SD1)

Cfm (SD2)

Cfm (ED1)

Cfm (ED2)
(mmwgp)

Cfm (R 1)

Cfm (E 1)
Selected
Length

Width

CFM

CFM
Sum

Mon

(4000 cfm / TSP 100 mm of

(4000 cfm / TSP 100 mm of

1 Garment Wash 3.00 6.63 2.80 19.89 214.02 9.18 1965.53 0.29 0 15 18 2.00 1.0 2.00 1 491 1.25 1.25 2.00 593 593 593 1 1
AHU-23 (Ground Floor)

AHU-23 (First Floor)

2 Visitor Change 3.00 4.80 2.80 14.40 154.94 9.18 1423.01 0.21 0 15 15 1.0 - 2 356 0.54 0.54 0.00 175 356 356 1 1

Recirculation
Un classified

Un classified
WC / 7 TR)

WC / 5 TR)
25±2°C

NA
3 Ladies Change 2.00 4.80 2.80 9.60 103.30 9.18 948.67 0.14 0 15 15 1.0 - 2 237 0.42 0.42 0.00 129 237 237 290 290 1 1

25.00
3902

6.23
100
4 Ladies Change 5.25 4.80 2.80 25.20 271.15 9.18 2490.26 0.37 0 15 30 1.0 - 2 623 2.45 2.45 0.00 1237 1237 1237 2 2

5 Gents Change 6.13 7.85 2.80 48.12 517.78 9.18 4755.26 0.70 0 15 15 1.0 - 4 1189 1.57 1.57 0.00 535 1189 1189 2 2

Total 117.21 1261.18 11582.72 1.71 2.00 2.00 11 2896 6.23 0.00 6.23 0.00 2.00 2669 3612 0 0 3612 290 0 290 0 0 7 0 0 0 7 0 0

1 Air lock Room 4.00 2.40 2.80 9.60 103.30 9.18 948.67 0.19 0 20 20 - 316 0.00 0.00 316 316 1 1

2 Air lock Room 4.00 2.40 2.80 9.60 103.30 9.18 948.67 0.19 0 20 20 - 316 0.00 0.00 316 316 1 1

(4000 cfm / TSP 75 mm of WC / 5 TR)

(4000 cfm / TSP 75 mm of WC)
20.65 1.83 2.80 37.79 406.62 9.18

Once through Ventialtion

SB1/EB1 (Ground Floor)

SB1/EB1 (Ground Floor)

3 Corridor 4808.52 0.95 0 20 20 - 1603 0.00 0.00 1603 1603 3 3

75 (Supply) 75 (Exhaust)
6.80 1.00 2.80 6.80 73.17 9.18
Un classified

Un classified
4.07 1.00 2.80 4.07 43.79 9.18

NA

NA
3670 0

3670

0.00
4 Janitor 2.90 1.00 2.80 2.90 31.20 9.18 286.58 0.06 0 20 20 - 96 0.00 0.00 96 96 1 1

5 Visitor Toilet 1.50 3.15 2.80 4.73 50.84 9.18 466.92 0.09 0 20 20 - 156 0.00 0.00 156 156 1 2

6 Ladies Toilet 1.50 3.15 2.80 4.73 50.84 9.18 466.92 0.09 0 20 20 - 156 0.00 0.00 156 156 1 2

7 Ladies Toilet 3.00 4.80 2.80 14.40 154.94 9.18 1423.01 0.28 0 20 20 - 474 0.00 0.00 474 474 2 4

8 Gents Toilet 3.50 4.80 2.80 16.80 180.77 9.18 1660.17 0.33 0 20 20 - 553 0.00 0.00 553 553 2 4

Total 111.41 1198.77 11009.47 2.17 0.00 0.00 0 3670 0.00 0.00 0.00 0.00 0.00 0 3670 0 0 0 3670 3670 0 0 0 5 7 0 0 0 5 13
EB-AHU-07

EB-AHU-07
(1000 cfm /

(560 cfm /
75mm of

75mm of
WC)

WC)
1 Wash 2.88 4.82 2.80 13.88 149.37 9.18 1371.78 0.00 1.0 - 701 0

701

75
Total 13.88 149.37 1371.78 0.00 0.00 0.00 0 0 0.00 0.00 0.00 0.00 0.00 0 0 0 0 0 0 701 0 0 0 0 0 0 0 0 0 0
EB-AHU-11

EB-AHU-11
(1000 cfm /

(486 cfm /
75mm of

75mm of
WC)

WC)
1 Wash 2.55 4.45 2.80 11.35 122.10 9.18 1121.36 0.00 1.0 - 656 0

656

75
Total 11.35 122.10 1121.36 0.00 0.00 0.00 0 0 0.00 0.00 0.00 0.00 0.00 0 0 0 0 0 0 656 0 0 0 0 0 0 0 0 0 0
EB-AHU-16

EB-AHU-16
(1000 cfm /

(278 cfm /
75mm of

75mm of
WC)

WC)
1 Wash 4.30 2.65 2.80 11.40 122.61 9.18 1126.05 0.00 1.0 - 416 0

416

75
Total 11.40 122.61 1126.05 0.00 0.00 0.00 0 0 0.00 0.00 0.00 0.00 0.00 0 0 0 0 0 0 416 0 0 0 0 0 0 0 0 0 0
EB-AHU-18

EB-AHU-18
(1000 cfm /

(353 cfm /
75mm of

75mm of
WC)

WC)
1 Tool Wash 2.15 4.10 2.80 8.82 94.85 9.18 871.10 0.00 1.0 - 641 0

641

75
Total 8.82 94.85 871.10 0.00 0.00 0.00 0 0 0.00 0.00 0.00 0.00 0.00 0 0 0 0 0 0 641 0 0 0 0 0 0 0 0 0 0

Grand Total 2983 32095 -- 363232 80 -- -- -- -- -- -- -- 142 -- 112 108 -- 172 148 218 103 208 74163 101250 -- -- 94237 19087 8496 12074 0 0 -- 0 0 -- -- 102 0 105 7 125 6 99 6 13

Page 5 of 5