Departemen Akademik 2009 Brilliant PRE MDE - FBS I

1. After helping delivery a baby, a doctor has to 7. 22 years old man was hospitalized with diagnosis
check pathologic condition. The pathologic of acute viral hepatitis due to hepatitis virus A. the
condition is? doctor order ALT test. This test is for…
a. The baby’s shape a. Prognosis
b. The baby’s viability b. Establish
c. The healthy of the baby’s sibling c. Monitoring
d. The mother’s abnormal congenital d. Diagnosis
e. The birth process to mother
8. The doctor usually tackle clinical situation by
2. A six month years old boy was taken to your clinic. taking a history illness. Is called…
His mother complaint that her baby’s didn’t to her a. Diagnose
and to his toys. When delivered, the baby was b. Diagnosis
premature and was given a high concentration of c. Anamnesis
oxygen in the incubator. The appropriate disease d. Prognosis
of the baby is… e. Diagnostic
a. Abnormal pulmonary disease
b. Hyaline membrane disease 9. A … plan is initiated after read / diagnosis.
c. Retrolentol plasia a. Diagnosis
d. Herpes virus b. Diagnostic
e. Anexia c. Prognosis
d. Diagnostic tool
3. A woman 47 years old come to general e. Placebo replacement
practitioner. She told that 8 month after
pregnancy, she didn’t fell anything. Her infant 10. Bond that bind carbohydrate molecule to other
didn’t move. What kind of death is it? molecule…
a. Anterpartum death a. Proteoglycans
b. Intrapartum death b. Dextran
c. Neonatal death c. Glycoprotein
d. Immature d. Glicosidic
e. Post-maturity
11. Which of glucose compound that abundant in
4. A new born baby was died when deliver to extracellular matrix?
emergency room. As the procedure, must be post a. Proteoglycans
moterm examination. What are the important b. Dextran
organ to emphasis the examination of newborn c. Glycoprotein
baby? d. Glicosidic
a. placenta
b. heart & lung 12. Which of the form of carbohydrate compound is
c. umbilical cord & placenta abundant in synovial joint?
a. Chitin
5. Anak lahir dengan bb 980 gr, termasuk… b. dextran
a. Post mature c. Glycogen
b. Immature d. Deoksiglyserad
c. Premature e. Spingomyelin

6. Ricketssiae will be transmitted by… 13. Which one of below is classified as disaccharide…
a. Lice a. Honey
b. Mice b. Corn syrup
c. Hydrolyzed lactose
d. Biscuit

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

14. The lowest glycaemia index food resource…. c. Hydrogen bond

a. White bread d. Non-covalent bond and hydrogen bond
b. Corn flakes
c. Banana 23. Which of the following structures that build from
d. Corn amino acids joint together include disulfide
e. Rice bonds…
a. Primary structure
15. What hormone that regulate blood glucose b. Secondary structure
decrease… c. Tertiary structure
a. Saturated phosposiderin d. Quartenary structure
b. Fatty acid e. Peptide structure
c. Phospoetinol
d. Insulin 24. Which is following region in protein that folding to
become alpha hexa and beta…
16. The role of glucagon in starvation is to… a. Primary structure
a. Decrease glycolisis b. Secondary structure
b. Decrease glucogenesis c. Tertiary structure
c. Increase glycogenolysis d. Quartenary structure
d. Increase proteolysis e. Peptide structure
e. Increase lypolysis
25. Which are the following bonds in protein that are
17. Karakteristik dari fat soluble vitamin? broken by reagen such as urea, sodium …, …,
a. Menggunakan carrier protein sulfat, mild OH- & H+.
b. Tidak menggunakan carrier protein a. Hydrogen bond & disulfide bond
b. Hydrogen bond & peptide bond
18. What part of protein that have protection c. Non-covalent bond & peptide bond
function? d. Non-covalent bond & hydrogen bond
a. Globin e. Disulfide bond & peptide bond
b. Albumin
c. Globulin -----globulin γ(immunoglobulin) 26. Which of the following (in conjugate between) bile
acid and glycine?
19. High quality protein source is … high biological a. Amide bond
value. b. Disulfide bond
a. Complete c. Glycosidic bond
d. Hydrogen bond
20. Which the following structure has two or more e. Peptide bond
than two sub unit of protein ?
a. Primary 27. α helix, β sheet, termasuk?
b. Secondary a. Primary protein
c. Tertiary b. Secondary protein
d. Quartenery c. Tertiary protein

21. Which protein that function is to protect ? 28. Which is the function of chlorine in stomach?
a. Globin a. Support calcium absorption
b. Spectrin b. Support nerve system
c. Globulin -----globulin γ(immunoglobulin)
29. Which is the classic form of dysgenesis?
22. Which type of bond is/are still exist when protein a. Cry du chat
denatured ? b. Down syndrome
a. Disulfide bond c. Edward syndrome
b. Non-covalent bond d. Patau syndrome

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

e. Turner d. Hydroxibutirate to glyceraldehide 3-phosphat

Cry du chat, down, patau, sama2 mengalami e. Fructose 1,6 phosphate to hydroxybutirate
retardasi mental. Jadi masih bingung and glyceraldehid 3 phosphat
jawabannya,
38. Chemiostatic reaction ?
30. Pengikatan enzim dan substrat dimana enzim Reaksi yang membentuk energy dari perbedaan
menyesuaikan bentuk aktif site terhadap bentuk konsentrasi dan perbedaan muatan listrik
substrat?
a. Induced fit
39. Which of the following will be found if cyanide is
31. Which of the following is modified to serve a added to tightly coupled mithocondria that are
cofactor for enzyme? active oxidizing succionate…
a. Cooper Soal ga jelas, yang pasti, cyanide itu mengganggu
b. Biotin complex IV. Tapi kalo di Tanya, DNP merupakan
c. Zinc uncoupler, yang nantinya electron tetap mengalir
d. Panthotenic acid tapi ATP tidak terbentuk.
e. Ascorbatic acid

32. Enzim acetil dehidrogenase tergolong kategori 40. Enzim succinate dehydrogenase masuk ke
apa? kompleks berapa?
a. Oksida-reductase Kompleks II

33. Grafik di berikut ini 41. Glukosa paling disukai oleh organ apa?
merupakan grafik inhibitor … Brain and adrenal glands

a. Kompetitif 42. Rumus BEE?

Male = 1kkal/kg/hours
34. All below are true about enzyms… Female = 0,9 kkal/kg/hours
a. As a biokatalisator
b. To identify organ damage 43. Seorang sekretaris ingin menurunkan 1 kg berat
c. To diagnose disease badannya dalam waktu satu bulan. Berapa kkal
d. Accelertat reaction without reacting yang harus dibuang perminggu?
e. All above true a. 250 b. 375 c. 500 d. 625

35. How is the chemical reaction in complex 1? 44. Seorang wanita ingin menaikan berat badannya
a. NADH2 → NAD+ + 2H+ + 2e- sebesar 1,5 kg dalam waktu 1 minggu. Berapa
b. NADH + H+ → NAD+ + 2H+ + 2e- kandungan zat gizi makanan yang harus
dikonsumsi dalam waktu 1 hari?
36. The mitochondria enzyme that carries out ATP %karbohidrat….,%lemak….,%protein….
synthesis is called….
a. Oxidative phosphorilation 45. Untuk mengukur penyebaran lemak dalam tubuh
b. ATP/ADP translocate harus dilakukan…
c. ATP synthase inhibitor a. Fat fold
d. NADH dehydrogenase b. Circumference
e. ATP Synthase c. Height
d. Weight
37. Reaksi enzim substrat catalytic reaction yang e. Post-maturity
menghasilkan high energy phosphate…
a. Phosporilation of glucose 46. Tekanan darah tinggi =
b. 2-phosphoglycerate to phosphoenol pyruvate a. Diseases
c. 3-phosphoglycerate to 2-phosphoglycerate b. infeksi

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

c. inflamasi 53. Which of the following factor is influenced by the

d. disability activity of enzyme ?
a. Half life reaction
47. Which of the following of the highest contain of b. Mechanism of reaction
potassium? c. Order of reaction
a. Ikan pepes d. Temperature of reaction
b. Jus wortel e. Rate of rection
c. Rendang Jawaban : rate of reaction

48. The cationic concentration of these molecules are 54. What happen to the reaction rate if temperature
abundant in Extracellular fluid? is higher than nedded for enzyme activity ?
Natrium a. Increase
b. Descrease
49. 22 years old man was hospitalized with diagnosis c. Constant
of acute viral hepatitis due to hepatitis virus A. The d. Stopped
doctor order ALT test. Dokter melakukan e. Equilibrium
pemeriksaan enzim ALT. Pemeriksaan tersebut. Jawab : Descrease
Untuk apa ?
a. Prognosis 55. The function of cofactor is
b. Establish a. As primary catalityc center
c. Monitoring b. As electron donor
d. Diagnosis c. Bridging group to bind substrate
Jawab : Confirm diagnosis d. Structure formation of enzyme
e. All of the above
50. Wich of the following is modified to serve as Jawab : As primary catalityc center
cofactor for enzyme ?
a. Cooper 56. The sigmoid phenomena of enzyme is refer to
b. Blutin a. Competitive inhibitor
c. Zinc b. Uncompetitive inhibitor
d. Panthotenic acid c. Noncompetitive inhibitor
e. Ascorbatic acid d. Allosteric site
Jawab : Panthotenic acid e. All enzyme
Jawab :
51. All below are true about enzymes ?
a. As biokatalisator 57. Enzyme activity is important in medical because
b. To indentify organ damage a. To predict prognosis
c. To diagnoses disease b. To monitor of treatment
d. Accelertat reaction without reacting c. To understand pathogenesis of disease
e. All above true d. To support diagnostic
Jawab : All above true e. All the above
Jawab :
52. The mitochondria enzyme that carries out ATP
synthesis is called ? 58. Sellect the following statements that is closely
a. Oxydative phosphorilation associated with zymogen
b. ATP/ADP translocate a. An inactive form of enzyme’
c. ATP synthase inhibator b. An active form of enzyme
d. NADH dehydrogenase c. Is not a group of enzyme
e. ATP synthase d. To catalyze blood clotting
Jawab :ATP syntase e. Is not found in human
Jawab :

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

59. If an inhibitor does not alter teh Km, the inhibition e. Lactate hydrogenase
is probably Jawab :
a. Competitive inhibitor
b. Noncompetitive inhibitor 65. What are the enzyme that specially increased in
c. Uncompetitive inhibitor blood when people suffering from liver disease ?
d. Not an inhibitor a. Lipoprotein lipase
e. None of the above b. Creatinine phosphokinase
Jawab : c. Aspartate transaminase
d. Phosphatise acid
60. What do we call an enzyme active affected with a e. Lactate hydroxylase
molecule bind to a certain site ? Jawab :
a. End product enzyme
b. Coenzyme enzyme 66. Which of the following describes a characteristic
c. Isoenzyme feature of enzymes obeying Michelis-Menten
d. Allosteric enzyme kinetics ?
e. Feedback enzyme a. The enzyme velocity is half the maximal rate
Jawab : when 100% of enzyme molecules contain
bound substrate
61. Which of the following can acetyldehyde b. The enzyme velocity is half the maximal rate
dehydration be classified as ? when 50% of enzyme molecules contain
a. Oxidoreductase bound substrate
b. Isomerise c. The enzyme velocity is its the maximal rate
c. Hydrolases when 100% of enzyme molecules contain
d. Ligase bound substrate
e. Lyases d. The enzyme velocity is its the maximal rate
Jawab : when all the subtraate molecules in a solution
are bound by the enzymes
62. Whch of the following given condition in an e. The enzyme velocity is independent to the
enzymatic reaction may appear irreversible? concentration of enzyme
a. High temperature
b. Under equilibrium condition 67. What is the condition that influence pyranose or
c. If the product is thermodynamically for more furanose?
stable than the reactant a. pH, angle, bond
d. If the product accumulate b. pH, temperature, angle
e. At high enzyme concentration c. Solvent composition, angle bond
Jawab : d. Solvent composition, bond, temperature
e. pH, solvent composition, temperature
63. unction of VB / UB primarily Jawaban E. Ph, solvent compositition, temperature
a. Enzyme Sumber slide 54 function and strucuture carbohydrate
b. Serotonin precursor
c. Coenzyme 68. Which one is gamma globulin?
d. Antagonists a. Lipoprotein
e. Antioxidant b. Nucleoprotein
Jawab : c. Metalloprotein
d. Hemoprotein
64. Which of the following enzymes will specially e. Glycoprotein
increased after a myocardial infarction Jawaban
a. Glucokinase
b. Creatinine phosphokinase 69. How many fatty acids that we can get from break
c. Glycogen phosphokinase down of 1 triglycerides?
d. Pyruvate deehydrogenase a. 1 fatty acid

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

b. 2 fatty acids 75. The true statement about 3D structure of protein:

c. 3 fatty acids a. The 3D structure is determined by sequence of
d. 4 fattyy acids amino acid
e. 5 fatty acids B. The 3D structure has non-covalent bonds
Jawaban C. 3 fatty acids C. The 3D structure only interact with hydrophobic
Sumber slide 16 lipids function and structure interaction
D. The 3D structure is not found in human
70. Lipid is a part of nutrient content in our food. E. The 3D structure is only important in enzyme
Which statement is true? molecule
a. 60% lipid in our food is triglycerol
b. Common foods source of stearic acid is 76. Which statement is associated with three
coconut dimensional
c. Most dangerous cholesterol is form structure?
coconut A. primary structure
d. Vinegar is source of acetic acid B. secondary structure
e. All of animal lipid is dangerous for our C. tertiary structure
health D. primary.secondary,tertiary structure
E. not depending in structure of protein
71. Our body receives most of its vitamin K from ...
BACTERY SYNTHESIS 77. Which of the following statement is true about 3D
Sumber soal Understanding Nutrition hal 388 no. 10 protein structure if it is heated at high
temperature?
72. Recommendation of dietary lipid ... A. amino acids will combined with other amino
a. Increase saturated fatty acid intake to acid
more than 10% of the energy intake B. protein will function at constant rate
b. Reduce cholesterol intake to less than 400 C. will lost it function
mg daily D. not effect at all to the protein structure
c. Reduce unsaturated fat iintake to less than Jawaban C
10% of the energy intake
d. Eat pllenty of poultry & dairy product 78. Protein can be denatured by which of the
e. Reduce total fat intake to 30% or less following?
energy intake A. Concentrated urea solution
B. Oxygen
73. Folding structure of protein exist in which C. Strong acid
structure? D. Concentrated ethanol solution
a. Primary, secondary E. Heat
b. Primary, tertiary Jawaban E
c. Secondary, tertiary
d. Secondary, quartenary 79. Which is isotonic solution?
e. Tertiary, Quartenary A. Glucose 0.9%
Jawaban B. CaCl2 0.9%
C. KCl 0.9%
74. Inefficient digestion or absorpsion in protein D. NaCl 0.9%
energy malnutrition is caused by failure of the Jawaban D
function of protein as ...
a. Peptide hormon 80. The body needs chloride, sodium, potassium, etc.
b. Regulate acid-base balance What
c. Component of muscle contraction are these solution are called?
d. Regulate water and electrolyte balance A. Acid
e. Enzyme is component of receptor in B. Base
enterocyte C. Electrolyte

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

D. Salt
E. Reactant 86. Which of this organic compound can interact with
Jawaban C central
Nervous System?
81. Albumin function is maintain osmotic pressure. A. benzene
What is B. carboxylic acid
the colligative properties that can stop osmotic C. cystein
pressure? D. diethyl ether
A. Boiling point elevation E. paraffin
B. Freezing point depression Jawaban D
C. Osmotic pressure
D. Vapour depression 87. Bovine insulin composed of two polypeptide
E. Vapour depression and osmotic pressure chains. What
Jawaban C kind of bond joined these two polypeptides?
A. Charge bond
82. Free radical can oxidized unsaturated fatty acid. B. Covalent bond
What type of bond & type of reaction occur? C. Disulfide bond
A. Single bond & redox reaction D. Hydrogen bond
B. Double bond & redox reaction E. Peptide bond
C. Triple bond & redox reaction Jawaban C
D. Sigma bond & redox reaction
E. Pi bond & redox reaction 88. Aldehyde and ketone are important groups for
Jawaban B identifiying
monosaccharides.What are the type of reaction
83. Which of the organic compound produce that
substance in occur?
transform with additional reaction? A. Group transfer reaction
A. Alcohol B. Redox reaction
B. Alkene C. Rearrangement reaction
C. Alkyne D. Hydrolysis
D. Ethers E. Elimination
E. Aliphatic Jawaban B
Jawaban B
89. Which of the following antibiotic has many
84. Which of the ketone bodies that has/have volatile member lactones
properties? ring in its structure?
A. Acetoacetic acid and hydroxybutyric acid A. Cannamycine
B. Acetoacetic acid and acetone B. Chloramphenicol
C. Hydroxybutyric acid acetone C. Erythromycine
D. Acetone D. Penicilline
E. Hydroxybutyric acid E. Tetracycline
Jawaban D Jawaban C

85. Which of the following bond can NOT make 90. Which of the following antibiotic has chloride in its
conformation? structure?
A. Sigma bond A. Bacitracin
B. Pi bond B. Chloramphenicol
C. Single bond C. Penicillin
D. Double bond D. Polymyxin
E. Triple bond E. Streptomycin
Jawaban B Jawaban B

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

C. Cellubiose
91. Cell wall of gram-positive bacteria consisting of D. Gentibiose
multiple E. Maltose
layers of these compound Jawaban A
A. Dextrans
B. Peptidoglycan 97. What is glycemic index is related to?
C. Glycosaminoglycan A. High protein level
D. Glycoprotein B. High lipid/fat level
E. Glycogen C. High fiber level
Jawaban B D. High absorption
E. More solid form à NOT SURE
92. Chondroitin Sulphate is an example of this Jawaban E
compound.
A. Dextran 98. All monosaccharides will be converted by the liver
B. Peptidoglycan into
C. Glycosaminoglycan which of the following?
D. Glycoprotein A. Fructose
E. Glycogen B. Galactose
Jawaban C C. Glucose
D. Sucrose
93. This compound is abundant in muscle E. Maltose
tissues;where it is Jawaban C
More immediately available for energy release
A. Dextran 99. Which food contains more lactose?
B. Peptidoglycan A. Malt syrup
C. Glycosaminoglycan B. Corn syrup
D. Glycoprotein C. Honey
E. Glycogen D. Soybean milk
Jawaban E E. Cow milk
Jawaban E
94. The compound that produce in the liver and acts as
100. Example of lecithin.
stored energy organ in an animal A. Prostaglandin
A. Dextrans B. Phospholipid
B. Peptidoglycan C. Cholesterol
C. Glycosaminoglycan D. Bile acid
D. Glycoprotein E. Sphingomyelin
E. Glycogen Jawaban B
Jawaban E
101. Which of the following compound is derived from
95. Dimmer of cellulose polymer. cholesterol?
A. Lactose A. Prostaglandin
B. Sucrose B. Phospholipid
C. Cellobiose C. Cholesterol
D. Gentibiose D. Bile acid
E. Maltose E. Sphingomyelin
Jawaban C Jawaban B

96. It is found in milk 102. Determinant of blood osmotic pressure.

A. Lactose A. Myoglobin
B. Sucrose B. Globulin

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

C. Hemoglobin B. Lipoprotein
D. Albumin C. Blood vessel
E. Water D. Monotriglycerides
Jawaban D E. Polytriglyceride
Jawaban: B. Lipoprotein
103. Which of the following is protein conformation Sumber soal Understanding Nutrition hal 169 no. 6
disease?
A. Albumin 109. Which part of amino acid chemical structure
B. Mad cow disease differentiates one
C. Hemoglobin from another?
E. Myoglobin A. double bonds
Jawaban B B. side groups
C. acid groups
104. Which of the following including essential fatty D. carboxyl group
acid? E. amino group
A. Stearic acid & palmitic acid Jawaban: B. Side Groups
B. Oleic acid & linoleic acid
C. Stearic acid & linoleic acid 110. What is the meaning of essential amino acid?
D. Palmitic acid & linolenic acid A.The body that can synthesize them for itself
E. Linoleic acid & linolenic acid B.The body that can synthesize it from fat
Jawaban C.The body that can synthesize it from
carbohydrate
105. LDL is produced at: D.The body that can’t make in sufficient quantity
A. Liver E.The body can’t synthesize it from vitamins
B. Gall bladder Jawaban: D. The body can’t make a sufficient
C. Small intestine quantity
D. Colon
E. Pancreas 111. Sometimes non-essential amino acid becomes
Jawaban A essential amino acid under special condition,
which is including conditionally essential amino
106. Triglycerides consist of the following acid?
A. 3 phospholipids attached to cholesterol A. Valine
B. 3 glycerol attached to lipid B. Methionine
C. 3 fatty acids attached to glucose C. Glutamine
D. 3 cholesterol attached to glycerol D. Leucine
E. 3 fatty acids attached to glycerol E. Isoleucine
Jawaban: E Jawaban: C. Glutamine

Sumber soal Understanding Nutrition hal 169 no. 2 112. What is the fate of amino acid after enter cell?
A. Oxidise to energy and store as protein
107. Chylomicron are produced by the B. Oxidise to energy and change to protein
A. Liver C. Change to lipid
B. Pancrease D. Store as protein
C. Gallbladder E. Build to enzyme
D. Small intestine Jawaban: B. Oxidise to energy and change to
E. Colon protein
Jawaban D. Small Intestine
Sumber soal Understanding Nutrition hal 169 no. 5 113. What function of protein should be avoided during
starvation?
108. What is the vehicle transport for lipid in blood? A. Protein as a building material
A. Micelle B. Protein as hormone

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

C. Protein as regulator of fluid balance 119. Which of these food contain the highest amount
D. Protein as acid-base balance of nucleic acid?
E. Protein as a source of energy A. chicken skin
Jawaban: E. Protein as a source of energy B. corn
C.
114. What is the meaning of protein turnover? D. red meat
A. The amount of protein on food before eating E. egg
B. The amount of protein absorb from diet Jawaban: D. Red meat
C. The amount of protein used for energy Sumber slide 12 resources and utility protein
D. The amount of protein found in albumin
E. The amount of protein synthesized and 120. What are vitamins?
degraded A. Inorganic molecules
Jawaban: E. The amount of protein stnthesized B. Need in large amount
and degradated C. Required in most catabolism reaction
D. Are soluble in either water or fat
115. Which of the foodstuff has a highest protein E. Performed best when linked in big molecules
quantity? Jawaban: D. Are soluble in either water or fat
A. rice, banana, soy Sumber soal Understanding Nutrition hal 358 no.2
B. rice, apple, milk
C. soy, apple, milk 121. Function of vitamin C?
D. soy, egg, milk A. Intrinsic factor
E. egg, asparagus, milk B. Antagonist
Jawaban: E. Soy, egg, milk C. Coenzyme
Sumber slide 12,14 resources and utility protein D. Antioxidant
E. Energizer
116. What is a pair of food that can provide COMPLETE Jawaban: D. Antioxidant
protein? Sumbersoal Understanding Nutrition hal 358 no.9
A. French fries and fried chicken
B. Rice porridge and chicken 122. What is good source of vitamin A?
C. Chicken and nasi gudeg A. Whole-wheat bread, green peas, tuna
D. Sticky black rice and green bean B. White bread, apples, noodles
E. Porridge rice and asparagus soup C. Oats, pintot beans
Jawaban: C. Chicken and nasi gudeg D. Liver, apricot, turnip
E. Corn, grapefruit juice, sunflower
117. Which of these food contain no protein? Jawaban: D Liver, apricot, turnip
A. rice Sumber soal Understanding Nutrition hal 388 no.4
B. milk
C. oil 123. What is the body precursor to make vitamin D?
D. soy bean A. Cholesterol
E. tofu B. Bilirubine
Jawaban: C. Oil C. B-Carotene
Sumber slide 12,14,15 resouces and utility protein D. Tocophenol
E. Creatinine phosphate
118. What is the effect if person take a lot of protein? A. Cholesterol
A. healthy Sumber soal Understanding Nutrition hal 388 no. 6
B. dehydration
C. obesity 124. What is the characteristic of fat soluble vitamin?
D. edema A. It is easily excreted
E. heart disease B. It is not stored in muscle tissue
Jawaban: E. Heart diseases C. It seldom cause toxicity
D. It is secreted from intestine by lipoprotein

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

E. It is secreted through urine 131. Which of the following groups of protein that
Jawaban B contains D & L term?
a. position of amino group from
125. What is the role of Vitamin C? b. position of carboxyl group from
A. Physiological nerve function c. position of side chain from
B. Required for fat formation d. position of amino group and carboxyl group
C. Required for collagen production e. position of amino acid in peptide chain
D. Coenzyme in lipid and carbohydrate metabolism
E. Promote heme-iron production 132. Mineral are commonly more abundant in man
Jawaban C than woman. Which mineral is more abundant in
woman/
126. Source of vitamin B: a. Calcium
A. Red meat, egg b. Phosphor
B. Banana, pineapple c. Magnesium
C. Fresh fish, milk d. Ferro
D. Pineapple, red meat e. Zinc
E. Milk, leafy vegetables Jawaban A
Jawaban E
133. Food source of iodine with high biovaiability is
127. What is the function of niacin? a. Whole grain
A. A coenzyme in….. b. Vegetables
B. A coenzyme of NAD and NADP c. Seeds
C. A coenzyme of ….. d. Egg
D. Synthesis of myelin e. Fish
E. Immune function Jawaban B
Jawaban B
134. Role of zinc in growth and development
128. What is true about vitamin B12? a. Cell integrity
A. Unstable when heating b. Muscle contraction
B. RDA is 300mg c. Neurotransmitter
C. source from tempe d. Metabolic process
D. deficiency disturb respiration e. Part of genetic material
Jawaban A Jawaban

129. Which of the following nutrients is the source of 135. Salenium acts as part of antioxydant process in ..
energy? a. Katalase
a. fat b. Gluthathion peroxidase
b. vitamin c. Superoxidase dismutase
c. mineral d. Work with vitamin C
d. fiber E. Associated with vitamin A
e. water Jawaban B
Jawaban A
136. The mithocondria enzyme that carries out ATP
130. Amino acid that can change the taste of food? synthesis is called...
a. Aaspargin a. Oxydative phorporilation
b. Aspartic acid b. ATP/ADP translocate
c. Glutamic acid c. ATP syntase inhibitor
d. Methionin d. NADH dehydrogenase
e. Histidin e. ATP synthase
Jawab :
E. ATP synthase

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 Departemen Akademik 2009 Brilliant
137. How is the chemical reaction in complex 1 ?
a. ......
b. NADH2  NAD+ + 2 H+ + 2 e-
c. NADH + H+  NAD+ + 2H+ + 2e-
d. .......
e. .......
Jawab :
C. NADH + H+  NAD+ + 2H+ + 2e-
Sumber : Harper 27th hal 102
138. Enzim substrat catalitik reaction yang
menghasilkan high energy phospat ....
a. Phosporilation of glucose
b. 2-phospoglycerate to phospoenol pyruvate
c. 3-phospoglyserate to 2 –phospoglyserate
d. Hydroxibutirate to glyceraldehide 3-
phospate
e. Fructose 1,6 phospate to hydroxybutirate
Jawab :
b. 2-phospoglycerate to phospoenol pyruvate
Sumber : Harper 27th hal 153
139. Chemiosmotic reaction is ?
Jawab :
Chemiosmotic teory :
ATP is produced by the utilization of energy
held in a gradient of charge and
consentration.
Sumber : slide bioenergenics hal 40
140. Which of the following will be found if cyanide is
added to tightly coupled mithocondria that are
active oxidizing succionate...
a. Subsequent addition of 2,4 dinitrophenol
will rouse ATP hydrolysis
b. Subsequent addition of 2,4 dinitriphenol
will restore succionate oxidation
c. Electron flow will cease but ATP synthase
will continue
d. Electron flow will cease but ATP synthase
can be restored by subsequent addition of
2,4 dinitriphenol
e. Subsequent addition of 2,4 dinitriphenol
and the phosphorilation inhibitor,
oligomycine will cause ATP hydrolase
141. Enzim succinate dehydroginase masuk ke kompleks
berapa?
Complex II
Sumber : Harper 27th hal 102
12
PRE MDE - FBS I
142. Why free energy liberated as heat, which is not
captured as high energy phosphate during ATP
production in respiratory chain, is not considered
as waste products?
d. free energy liberated as heat will maintain
body
143. Complex II in transport electron chain?
Jawab: bernama suksinat-Q-reduktase
dihambat oleh malonate. Substrat yang lebih
positif potensialnya (FAD) dibanding NADH
144. In tissue hypoxia, low ATP menyebabkan tingginya
produksi laktat (lactid acidose). Hal ini karena...
a. Low ATP stimulate conversion
phosphofructokinase to pyruvate
b. High ATP inhibit conversion pyruvate to
lactate with LDH
c. Low ATP stimulate conversion pyruvate to
fosfoenol pyruvate with pyruvate kinase
d. High ATP inhibit activity hexocase
e. High ATP inhibit activity of ??
Jawab: B. High ATP inhibit conversion
pyruvate to lactate with LDH
Sumber Harper Bab 18 resp.chain
145. Decarboxylase is a group of?
a. Oxidase
b. Transferase
c. Hydrolase
d. Lyase
e. Isomerase
146. What is the covalent bond formed between
substrate and glucose-6-phospate anzyme?
a. Phospate-enzyme
b. Acyl-enzyme
c. Schibber’s fact
d. All of the above
e. None of the above
147. True about phosphorylase kinase except...
a. In active form, if bind with ATP
b. In inactive form, if bind with ATP
c. Active when binding with ATP
d. Active when releasing from ATP
e. Bind with phosphate organic
148. The final product of stage III?
a. ATP
b. Glucose
 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

c. ADP 3. Inorganic phosphate

d. Amino acid 4. Pyrophospate
e. AMP
155. In biological system, the energy which is in the
149. The step of the electron transfer chain can be form of chemical energy, used to generate the
summarized as follows? living process such as?
a. NADHNADH2CoQCyt.c 1. Muscular contraction
Cyt.oxidase 2. Nerve impulse conduction
b. NADHNADH2Cyt.cCoQ 3. Active transport
Cyt.oxidase 4. Flagella movement
c. NADHCoQFADH2Cyt.c Jawab :1,2,3,4
Cyt.oxidase
d. FADH2NADHCoQCyt.c 156. The enzyme(s) stated below act(s) on proton
Cyt.oxidase pumps in ETC?
e. All incorrect 1. CoQ : Cyt.c reductase
2. NADH : CoQ reductase
150. By reaction of glycolysis, the TCA and oxidative 3. Cyt.c oxidase
phosporilation, the complete oxidation of one 4. FADH2 : CoQ reductase
molecule of the substrate written below, will yield Jawab : 1,2,3
three molecule of?
a. Ascorbic acid 157. Terms for anabolic reaction is/are?
b. Succinate 1. Lipogenesis
c. Glyseraldehydes-3-phospate 2. Protein synthesis
d. NADH 3. Glycogenesis
e. FADH2 4. Glyconeolysis
Jawab : 1,2,3
151. In glycolysis, ATP synthesis is catalized by?
a. Hexokinase 158. Terms for catabolic reaction is/are?
b. Phosphofructokinase-I 1. Protein synthesis
c. Glyceraldehyde-3-phospate 2. Lipolisis
dehydrogenase 3. Gluconeogenesis
d. Phosphoglycerate kinase 4. Glycolysis
e. Lactate dehydrogenase Jawab : 2,4

152. Several process stated below might play roles in 159. Basic understanding about metabolic is/are?
the catabolism of metabolic organic fuels... 1. Chemical reaction
1. Electron transport 2. Related to energy
2. TCA 3. Building block production
3. Oxidative phosporylation 4. Insufficient to provide substrate
4. Beta Oxidation Jawab : 1,2,3

153. The statements below that fit on NAD+ and 160. Proton gradients are interconvertible currency of
NADP+ coenzymes is/are... force in the biological system. They power a
1. Derivate of niacin variety of energy requiring process such as?
2. NAD+ act on anabolic reactions 1. NADH synthesis
3. Act on redox reactions 2. ATP production
4. NADP+ act on catabolic reactions 3. Heat production
4. Active transport
154. In biological system, ATP can be gained from? Jawab : 2,4
1. Adenosin diphospate
2. Adenylic acid 161. Enzyme function reductase needed?

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

1. Thiamin 2. SO2 + H2O H2SO4

2. Niacin 3. 2K + 2H2O  2 KOH +H2
3. Riboflavin Is a non redox reaction...
4. Ascorbic Acid a. (1)
Jawab : 1,2,3 b. (2)
c. (1) and (2)
162. Enzyme that act to breaking away of a small d. (1) and (3)
molecule such as H2O from substrate? e. (2) and (3)
a. Lyases
b. Hydrolases 167. Oxidation a primary alcohol in deliver, result a....
c. Isomerases a. Carboxylic acid
d. Ligases b. Alcohol
e. Oxidoreductases c. Water
d. Keton
163. The reaction of the glucose with the cupric oxide. e. Aldehide
This is..... reaction Jawab :
a. The group transfer reaction E. aldehide
b. The redox reaction
c. The elimination reaction 168. Balance the following oxidation of methyl alcohol,
d. The isomerisation reaction CH3OH, to formic acid, HCHO2, using the
e. The arrangement reaction dichromate ion, Cr2O72-, in an acidic medium?
Jawab : a. CH3OH+Cr2O72- +H2O  HCHO2 + Cr3+ + 7H2O
b. redox reaction b. 3 CH3OH + Cr2O72- + 14H+  3HCHO3 + Cr3+ +
7H2O
164. In the body the electron transport can be blocked c. CH3OH + Cr2O72- + 14H+ + 7H2O + 6e 
by? HCHO3 + 2Cr+ + 7H2O
a. Rotenone d. 3 CH3OH + 2 Cr2O72- + 16H+  3HCHO2 +
b. Cyanide 4Cr3+ + 11 H2O
c. Carbon monoxide e. 3 CH3OH + Cr2O72- + 14H+  3HCHO2 + 4Cr3+
d. Dinitro phenol + 7H2O
e. All the answer correct
Jawab : 169. The form of tetrahedral intermediate was
E. all the answer correct presentated at...
a. The group transfer electron
165. Cellular respiration is the process of the oxidizing b. The redox reaction
food molecules, like glucose, to carbon dioxide c. The elimination reaction
and water. The process occurs into phase : d. The isomeration reaction
glycolisis and oxidation of pyruvic acid, glycolisis in e. The arrangement reaction
this process is ? Jawab :
a. Breakdown of food to a glucose a. The group transfer electron
b. Breakdown of food to a fructose
c. Breakdown of glucose to a pyruvic acid 170. What is the oxidation number of carbon in ethane,
d. Breakdown of glucose to a carbon dioxide C2H6 and nitrogen in nitrate ion NO3- ....
and water a. C=+3, N=+3
e. Breakdown of food to a carbon dioxide and b. C=-3, N=+3
water c. C=-3, N=+5
Jawab : d. C=+4, N=+3
c. Breakdown of glucose to a pyruvic acid e. C=-4, N=+5
Jawab :
166. Which one among C. C=-3, N=+5
1. N2 + 3H2  2 NH3 171. Consider the following two chemical equations :

14
 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

C(s) + ½ O2 (g)  CO (g) Δr H(1) =-110,5 kJ a. The minimum collision energy of reaction
CO (g) + ½ O2  CO2 (g) Δr H(2) = -283,0 b. The middle collision energy of reaction
kJ c. The maximum collision energy of reaction
How many joule Ar H(3)=..... d. The internal energy for collision of reaction
For below equation e. The potential energy for collision of
a. -393,5 kJ reaction
b. 393,5 kJ
c. -172,5 kJ 177. What is the net energy which resulted of the
d. 172,5 kJ reactants energy minus the products energy
e. -27,8 kJ called?
a. The energy of reaction
172. System change by absorbing the heat as high as b. The energy of production
485 kkal , inner energy system is 310 kkal. Work c. The energy of collision
done by the system is ? d. The energy of activation
a. 175 kkal e. The energy of reacting mixture
b. 795 kkal
c. -175 kkal 178. Which one the compounds below that the
d. -795 kkal element Mn has the highest oxidation number?
e. All wrong Oxidation number of : O=-2, K=+1, S=+6
Jawab : a. MnO2
b. MnSO4
173. Thermodynamic of our body, except c. MnO+2
a. Inside in our body is open system d. KMnO4
b. Our body is open system e. K2MnO4
c. Our body is loose system Jawab : D. KMnO4
d. A and c correct
e. No thermodynamic process 179. D-glucose react with CuSO4 solution produces D-
glukonat and CuO. What is the reaction...
174. .... used in muscle contraction. a. Group transfer reaction
a. AMP b. Redox
b. ADP c. Elimanation reaction
c. ADP + Pi d. Isomerization reaction
d. ATP e. Rearrangement reaction
e. AAP
Jawab : 180. Calculate the oxidation number of carbon in
D. ATP (a)C2H2, (b)C2H4, (c) C2H6
a. (a)1 ; (b)1 ; (c)1
175. A chemical reaction is .... b. (a)1 ; (b)2 ; (c)1
a. A process whereby one or more substance c. (a)1 ; (b)2 ; (c)3
unite temporarily but come away d. (a)1 ; (b)1 ; (c)2
unchanged e. (a)2 ; (b)1 ; (c)2
b. A process whereby one or more Jawab :
substances are prevented from forming a
different substances 181. Does the series from compounds (a) to (c).
c. A process where one or more substance a)C2H2, (b)C2H4, (c) C2H6 which can be carried
react to form a different substance out experimentally, represent:
d. All of the above a. Oxidation
e. None of the above b. Reduction
c. Redox
176. What is define the activation energy of a chemical d. Neutralization
reaction? e. Acid-base

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

c. Radiant energy
182. What is the concept of the thermodynamic II ? d. Potential energy
a. Spontaneous process and entropy e. Thermal energy
b. Irreversible process and enthalpy Jawab :
c. Entropy and enthalpy A. Kinetic energy
d. Spontaneous process and enthalpy
e. Entropy, work and heat 187. What is the concept of the thermodynamic I ?
Jawab : a. Spontaneous process
A. Spontaneous process and entropy b. Work and heat
Sumber : Harper 27th hal 88 c. Irreversible process
d. Entropy
183. What is the define of the endergonic reaction? e. Nonspontaneous process
Endergonic reaction is a reaction that?
a. Produce an energy output 188. What is the thermodynamic law that represent
b. Release heat the change of energy in the redox reaction in the
c. Require an energy input body?
d. Did not transferred energy a. Thermodynamic I
e. Absorb heat b. Thermodynamic II and III
Jawab : c. Thermodynamic I and II
C. require an energy input d. Thermodynamic I and III
Sumber : Harper 27th hal 89 e. Thermodynamic II

184. The reaction of glucose become to glucose 6 189. In thermodynamic I, energy of the system can
phospate as follows: change into two different ways. What are they?
Pi + glucose ↔ glucose-6-P + H2O AG0 = +13,8 a. The changes of spontaneous and
(kJ.mol-1) irreversible process
What is the reaction above called? b. The changes of reactants and products
a. Exergonic reaction c. The changes of reversible and irreversible
b. Endotermic reaction processes
c. Endergonic reaction d. The changes of enthalpy and free energy
d. Kinetic reaction e. Work and heat
e. Eksothermic reaction
Jawab : 190. What process follows spontaneous change?
ΔG positive = endergonic a. Inner energy
Sumber : Harper 27th hal 89 b. Entropy
c. Enthalpy
185. What happen to entropy if spontaneous process d. Product
occur? Entropy of... e. Reaction
a. The universe tends stable Jawab :
b. The universe tends towards a maximum B. entrophy
c. The universe tends unstable Sumber : Harper 27th hal 88
d. The universe tends to disorder
e. The univers tends towards a minimum 191. What is the form of energy that is produced from
Jawab : the process in living organism?
B. the universe tends towards a maximum a. Inner
Sumber : Harper 27th hal 88 b. Gibbs
c. Helmonat
186. What is the energy that was produced by a moving d. Redox
object? e. Glycolysis
a. Kinetic energy Jawab :
b. Chemical energy E. glycolisis

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

Sumber : slide bioenergetics hal 3 b. Mechanical energy

c. Nuclear energy
192. What is bioenergetics? d. Thermal energy
a. Electronic energy e. Electrical energy
b. Rotational energy Jawab :
c. Vibration energy
d. Transduction energy 198. The thermal energy added to the system and the
e. Molecular energy work done on the system is ?
Jawab : a. ΔH
b. ΔG
193. What are types of transduction energy? c. ΔU
a. Movement, release, and the use of energy d. ΔA
b. Movement, release, and storage of energy e. ΔS
c. Release, storage, and use of energy Jawab :
d. Storage, release, use, and movement of A. ΔH
the energy Sumber : Harper 27th hal 88
e. Movement, storage, and use of energy
199. If standart enthalpies of formation are known for
194. What type of chemical energy conversion take each reactant and product, you can determine
place during muscle movement? values based on ?
a. Electrical energy a. The hess law
b. Mechanical energy b. The 1st law of thermodynamic
c. Nuclear energy c. The 2nd law of themodynamic
d. Thermal energy d. The 3rd law of thermodynamic
e. Electromagnetic energy e. The internal energy
Jawab : Jawab :

195. The enzyme which catalize the synthetic joining of 200. A tendency for materials become more physically
two molecules coupled with the breakdown of disorganized is a?
adenosine triphosphate are called? a. Enthalpy change
a. Transferase b. Spontaneous change
b. Oxidoreductase c. Non spontaneous change
c. Ligase d. Free energy gibbs change
d. Isomerise e. Free energy helm holtz
e. Lyases Jawab :
Jawab :
B. Mechanical energy 201. All truly perfect crystals at absolute zero
temperature have zero entrophy is ?
196. Lactate dehydrogenase isoenzymes can be used as a. The 1st law of thermodynamic
diagnostic tools of ? b. The 2nd law of themodynamic
a. Myocardial infraction c. The 3rd law of thermodynamic
b. Bone disease d. The internal energy
c. Liver disease e. The gibbs energy
d. Acute pancreatitis Jawab :
e. Prostate carcinoma
Jawab : 202. G values to be a negative number indicates that
A. Myocardial Infraction reaction?
a. Spontaneously
197. Chemical energy in the body was changed to b. Nonspontaneously
become? c. Reverse change tends to occur
a. Electromagnetic energy d. An equilibrium situation

17
 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

e. Reversible 208. Inhibitor complex IV?

Jawab : Jawaban : cyanide, CO, dan H2S
A. Spontaneously Sumber : Harper edisi 27 hal 107
Sumber : Harper 27th hal 88
Alas an : If ΔG is negative, the reaction Which of the following compound provides energy for
proceeds spontaneously. the formation of ATP?
a. NAD+
203. The reaction that indicates spontancity, if.... b. ADP
a. Enthropy is a positive number and free c. FMN
energy G is a negative number Jawaban : A
b. Enthopy is a negative number and free Sumber : Harper edisi 27 hal 107
negative number
c. Enthropy is a positive number and free 209. These are inhibitor to the respiratory chain,
positive number except...
d. Entalphy positive number and free energy a. Barbiturate
free b. Antymicine A
e. Entalphy negative number and free c. Dimercarpol
positive number. d. Cyanide
Jawab : e. Dinitrophenol
A. Entrophy (+), free energy G (-) Jawaban : E
Sumber : Harper 27th hal. 88 Sumber : Harper edisi 27 hal 107

204. The mitochondria enzyme that carries out ATP 210. Below are biologically important high energy
synthesis is called sources, except...
a. Oxidative phosphorilation a. PEP
b. ATP/ADP translocate b. GTP
c. ATP synthase inhibitor c. AMP
d. NADH dehydrogenase d. Creatin phosphate
e. ATP synthase e. 1,3-Biphosphoglycerate
Jawaban : E Jawaban : E
Sumber: Harper edisi 27 hal 105 Sumber : Harper edisi 27 hal 90

205. Chemiostatic reaction?
Jawaban : reaksi yang membntuk energi dari
perbedaan konsentrasi dan perbedaan muatan lisktrik
Sumber : Harper edisi 27 hal 105
206. Enzim succinate dehydrogenase masuk ke
kompleks berapa?
Jawaban : complex II
Sumber : Harper edisi 27 hal 103
211. The step of the electron transfer chain can be
summarized as follows?
a. NADH-NADH2-CoQ-Cyt.c-Cyt.oxidase
b. NADH-NADH2-Cyt.c-CoQ-Cyt.oxidase
c. NADH-CoQ-FADH2-Cyt.c-Cyt.oxidase
d. FADH2- NADH-CoQ-Cyt.c-Cyt.oxidase
e. All incorrect
Jawaban : E
Sumber : Harper edisi 26 hal 96

207. Condition factor that affect oxidative 212. In the body the electron transport can be blocked
phosphorilation by?
a. The presence of ATP a. Retonone
b. The presence of NAD b. Cyanide
c. The presence of FAD c. Carbon monoxide
d. The presence of NADH d. Dinitro phenol
Jawaban : D e. All the answer correct
Sumber : Harper edisi 27 hal 106 Jawaban : B
Sumber : harper edisi 26 hal 95

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

e. ATP synthase
213. Cyanide (CN-) is/are? Jawab : ATP syntase
1. Deadly poisioning substance
2. Inorganic ion 219. Which of the following factor is influenced by the
3. Exist in water as HCN activity of enzyme ?
4. A weak acid a. Half life reaction
Jawaban : b. Mechanism of reaction
Sumber : c. Order of reaction
d. Temperature of reaction
214. Cyanide is widely used in industry especially for? e. Rate of rection
1. Cosmetic Jawaban : rate of reaction
2. Metal cleaning
3. Poison 220. What happen to the reaction rate if temperature
4. Electroplating is higher than nedded for enzyme activity ?
Jawaban : a. Increase
Sumber : b. Descrease
c. Constant
215. 22 years old man was hospitalized with diagnosis d. Stopped
of acute viral hepatitis due to hepatitis virus A. The e. Equilibrium
doctor order ALT test. Dokter melakukan Jawab : Descrease
pemeriksaan enzim ALT. Pemeriksaan tersebut.
Untuk apa ? 221. The function of cofactor is
a. Prognosis a. As primary catalityc center
b. Establish b. .As electron donor
c. Monitoring c. Bridging group to bind substrate
d. Diagnosis d. Structure formation of enzyme
Jawab : Confirm diagnosis e. All of the above
Jawab : As primary catalityc center
216. Wich of the following is modified to serve as
cofactor for enzyme ? 222. The sigmoid phenomena of enzyme is refer to
a. Cooper a. Competitive inhibitor
b. Blutin b. Uncompetitive inhibitor
c. Zinc c. Noncompetitive inhibitor
d. Panthotenic acid d. Allosteric site
e. Ascorbatic acid e. All enzyme
Jawab : Panthotenic acid Jawab :

217. All below are true about enzymes ? 223. Enzyme activity is important in medical because
a. As biokatalisator a. To predict prognosis
b. To indentify organ damage b. To monitor of treatment
c. To diagnoses disease c. To understand pathogenesis of disease
d. Accelertat reaction without reacting d. To support diagnostic
e. All above true e. All the above
Jawab : All above true Jawab :

218. The mitochondria enzyme that carries out ATP 224. Sellect the following statements that is closely
synthesis is called ? associated with zymogen
a. Oxydative phosphorilation a. An inactive form of enzyme’
b. ATP/ADP translocate b. An active form of enzyme
c. ATP synthase inhibator c. Is not a group of enzyme
d. NADH dehydrogenase d. To catalyze blood clotting

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

e. Is not found in human b. Creatinine phosphokinase

Jawab : c. Glycogen phosphokinase
d. Pyruvate deehydrogenase
225. If an inhibitor does not alter teh Km, the inhibition e. Lactate hydrogenase
is probably Jawab :
a. Competitive inhibitor
b. Noncompetitive inhibitor 231. What are the enzyme that specially increased in
c. Uncompetitive inhibitor blood when people suffering from liver disease ?
d. Not an inhibitor a. Lipoprotein lipase
e. None of the above b. Creatinine phosphokinase
Jaawab : c. Aspartate transaminase
d. Phosphatise acid
226. What do we call an enzyme active affected with a e. Lactate hydroxylase
molecule bind to a certain site ? Jawab :
a. End product enzyme
b. Coenzyme enzyme 232. Which of the following describes a characteristic
c. Isoenzyme feature of enzymes obeying Michelis-Menten
d. Allosteric enzyme kinetics ?
e. Feedback enzyme a. The enzyme velocity is half the maximal
Jawab : rate when 100% of enzyme molecules
contain bound substrate
227. Which of the following can acetyldehyde b. The enzyme velocity is half the maximal
dehydration be classified as ? rate when 50% of enzyme molecules
a. Oxidoreductase contain bound substrate
b. Isomerise c. The enzyme velocity is its the maximal rate
c. Hydrolases when 100% of enzyme molecules contain
d. Ligase bound substrate
e. Lyases d. The enzyme velocity is its the maximal rate
Jawab : when all the subtraate molecules in a
solution are bound by the enzymes
228. Which of the following given condition in an
enzymatic reaction may appear irreversible? 233. Prolonged period, feral distress, heart beat slow,
a. High temperature pallor & weak, skin yellowish…
b. Under equilibrium condition a. Hyaline membrane disease
c. If the product is thermodynamically for b. Retrolental fibroplasias
more stable than the reactant c. Cogenital disease
d. If the product accumulate d. Asphiksia pallid
e. At high enzyme concentration e. Fetal distress
Jawab :
234. 27 years old lady has strength habitat and other
229. Function of VB / UB primarily symptom ?
a. Enzyme a. Inflammation
b. Serotonin precursor b. Malformation
c. Coenzyme c. Disorder
d. Antagonists d. Syndrome
e. Antioxidant e. Pain
Jawab :
235. A 30-years old man come to visit his family doctor
230. Which of the following enzymes will specially with complain a headache, chilled, abnominal
increased after a myocardial infarction disorder, and diarrhea. On physical examination
a. Glucokinase

20
 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

he was liver enlargement. What sign of this c. CH-lipid

disease? d. CH-H2O
a. Abnominal disorder e. CH-lipid & protein
b. Chilled
c. Headache 242. Which one is gamma globulin?
d. Diarrhea a. Lipoprotein
e. Liver enlargement b. Nucleoprotein
c. Metalloprotein
236. Act or process to decide nature of disease by d. Hemoprotein
examination? e. Glycoprotein
a. Diagnose
b. Diagnosis 243. How many fatty acid that we can get from break
c. Diagnostic down of 1 triglycerides?
d. Diagnostic tools a. 1 fatty acid
e. Prognosis b. 2 fatty acids
c. 3 fatty acids
237. If a patient doesn’t need a drug for his illness, the d. 4 fatty acids
treatment is called… e. 5 fatty acids
a. Ex juvantibus
b. Pharmacologic 244. Lipid is a part of nutrient content in our food.
c. Non pharmacologic Which stestment is true?
d. Advice treatment a. 60% lipid in our food is triacyglycerol
e. Placebo b. Common food source of stearic acid is
238. Which of the following is the most structure to coconut
represent enantiomer? c. Most dangerous cholesterol is from
a. Chair coconut
b. Boot d. Vinegar is a source of acetic acid
c. Envelope e. All of animal lipid is dangerous for our
d. Linier health
e. Circle
245. Recommendation of dietary lipid…
239. What is the condition that influence pyranose or a. Increase saturated fatty acid intake to
furanose? more than 10% of the energy intake
a. pH , angle, bond b. Reduce cholesterol intake to less than 400
b. pH, temperature, angle mg daily
c. solvent composition, angle bond c. Reduce unsaturated fat intake to less than
d. solvent composition, bond, temperature 10% of the energy intake
e. pH, solvent composition, temperature d. Eat plenty of poultry & dairy product
e. Reduce total fat intake to 30% or less
240. Which of the following carbon uses for differing energy intake
anomer?
a. C1 246. Inefficient digestion or absorption in protein
b. C2 energy malnutrition is caused by failure of the
c. C3 function of protein as…
d. C4 a. Peptide hormone
e. C5 b. Regulate acid-base balance
c. Component of muscle contraction
241. Which of the following structures of CH has role d. Regulate water and electrolyte balance
in mediating and modulating cell? e. Enzymes is component of receptor in
a. CH-CH enterocyte
b. CH-protein

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

247. Folding structure of protein exist in which a. Whole gain

structure? b. Vegetables
a. Primary, secondary c. Seeds
b. Primary, tertiary d. Egg
c. Secondary, tertiary e. Fish
d. Secondary, quartenary
e. Tertiary, quartenary 254. Role of zinc in growth and development…
a. Cell integrity
248. Which of the following nutrients in the source of b. Muscle contraction
energy… c. Neurotransmitter
a. Fat d. Metabolic process
b. Vitamin e. Part of genetic material
c. Mineral
d. Water 255. Selenium acts as part of antioxidant process in…
e. Fiber a. Katalase
b. Gluthahion peroxidase
249. Amino acid that can change the taste of food? c. Superoxide dismultase
a. Asparagin d. Work with vit. C
b. Aspartic acid e. Associated with vit. A
c. Glutamic acid
d. Methionin 256. Characteristics of water soluble vitamins?
e. Histidin a. Adsoption first into lymph then to blood
b. Require protein carrier in transport
250. Which of the following groups of protein that c. Need in periodic dose
contains D & L term? d. Less readily excreted by kidney
a. Position of amino group from α e. Toxic when uncontrolled consumption with
b. Position of carboxyl group from α supplement
c. Position of side chain from α
d. Position of amino group and carboxyl 257. Rate of vitamin C in macronutrient metabolism is?
group a. A part of coenzyme A in energy
e. Position of amino acid in peptide chain metabolism
b. Helps to convert tryptophan to niacin and
251. Maintenance of balance nitrogen is important to serotonin
support specific condition. Adequate intake and c. Help to breakdown some fatty acid and
positive balance nitrogen occur in this condition… amino acid
a. Child with acute diarrhea d. Collagen synthetis to provide matrix for
b. Pregnant women bone growth
c. 20 years old student e. Part of coenzyme used in glycogen
d. Lactating women with chronic disease
e. Adult with high PA 258. Although enzyme catalization is reversible, which
of the following reaction may appear irreversible?
252. Minerals are commonly more abundant in man a. If the product is more stable than reactant
than woman. Which mineral is more abundant in b. Under equilibrium
woman? c. If a product accumulates
a. Calcium d. High enzyme concentration
b. Phosphor e. High temperature
c. Magnecium
d. Ferro 259. Which of the situation can be best increase rate
e. Zinc reaction in competitive inhibitor on complex
enzyme?
253. Food source of iodine with high bioavailability is… a. Increase enzyme

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

b. Increase coenzyme e.
c. Increase substrat 266. Hydrolytic reaction which drive favorable
d. Increase temperature a. NAD
e. Increase pH b. FAD
c. FMN
260. What are the enzyme that specially increased in d. NADH2
blood when people suffering from liver disease? e. FADH
a. Lipoprotein lipase
b. Creatine phospokinase 267. Which of the following compound provides energy
c. Aspartate transminase for the formation of ATP?
d. Phosphate acid a. NAD+
e. Lactate hydroxylase b. ADP
c. FMN
261. Initial reaction rate depends on? d. FAD
a. Vm e. NADH+
b. Km
c. S 268. Electron derived from many substrate may use the
d. E electron transport cahin because ?
e. All above a. The substrate are oxidized by enzyme
linked to oxidized nicotamide or from
262. Stable form between C & C at temperature are adenine dinucleotide
because? b. Each substrate is oxidized in the
a. The energy of molecule mitochondria
b. Van der walls c. Each substrate is oxidize by the same
c. hydrophobic bonds enzyme
d. hydrogen bonds d. Proton from each substrate are used to
from water
263. Electron FADH move via membrane bont electron e. Electrons from each substrate are
carry inner mitochondria to … transferred to adenosine triposphat
a. Regenerating NAD+
b. Regenerating NADH 269. Which of following characteristic of primary
c. Regenerating FADH cartilage that differ it from another?
d. Regenerating glucose a. Its predominat cell type is a mesenchimal
e. Regenerating piruvate derivative
b. Its secretes ectracellular matrix
264. Non-protein catalytic enzyme is found in … c. Its extracellular matrix is collagen
a. Allosteric enzyme d. It lack of blood vessel
b. Abzymes
c. Ribozymes 270. The chemiosmotic theory propose ATP is formed
d. DNA enzyme because of which one of the following reasons…
e. Ribonuclease a. A change in the permeability of the inner
mitochondrial membrane toward ADP
265. In tissue hypoxia, low ATP menyebabkan b. ATP is pumped out of the matrix into the
tingginya produksi laktat , hal ini karena? inner membrane space
a. Low ATP stimulate conversion c. The formation of high energy bonds in
phosphofruktokinase to pyruvate mitochondrial protein
b. High ATP inhibit conversion pyruvate to d. A protein gradient forms across the inner
lactate with LDH membrane
c. Low ATP stimulate conversion pyruvate to e. Protons are pumped into the
fosfoenol pyruvate with pyruvate kinase mitochondrial matrix
d. High ATP inhibit activity hexocase

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

271. If she succeed gain weight, what is the

compotition of her new weight?
a. Fat
b. Water
c. Protein
d. Mineral
e. Vitamin

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

Teman-teman masih ingat slide yang diberikan mengenai karbohidrat, yang slidenya mencapai 147 slide? Berikut ini
merupakan halaman-halaman slide yang mungkin saja keluar di MDE nanti, karena ini kisi-kisi

Structure and Function;Carbohydrate

13, 14) about enantiomers
23) Ketotretose which is called erythrulose, has only one pair of enantiomers
38) N-linked oligosacharida, o-linked-stabilize proteins
40, 41
47) C-C-C bond angles are about 109 0 and the C-O-C angle is about 1180
The different bond angles are called conformational isomers

50) istilah dalam KH, kofigurasi dan konformasi

58, 60, 63, 65
68) contoh penentuan glukosa pada urin penderita diabetes
69
71) sorbitols, alditols, diabetic’s eye, cataracts
73) glicosamine & galactosamine -> obat encok
78) GlcNAc or NAG
81) cobain & amygdalin -> obat jantung; non reducing sugar
83) contoh adanya ikatan glikosida dalam senyawa yang digunakan sebagai obat
84) contoh senyawa sebagai pengharum pada pembuata kue / roti
85) vanilin β-D-glukosida
86) sucrosa, lactosa, and trehalosa
88, 91
92) glucose residu, reducing, sucrose in nonreducing sugar
93) contoh oligosakarida -> disacharida -> lactose
94) Hydroxyl group on carbon 1, α or β? Jawabanya β
96) honey -> sucrose
100) homopolysaccharides
102, 107
108) amylodextrin, erythrodextrin, achrodextrin
112) glykogen
113) dextran -> hypovdemic shock -> bahan infus
120) heparin anti-koagulan
121)glukosa aminoglycans -> hyluronate, dermatan sulfate
123) skin and connective tissue
125) keratan sulfate
127) synovial fluids of joins
128, 130
131) antibody
138, 141
142) A, B, O blood group; o-linked-stabilize proteins
143, 144, 145

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 Departemen Akademik 2009 Brilliant PRE MDE - FBS I

Untuk protein kisi-kisi yang waktu itu didikte-in

Structure and Function; Protein

Protein -> fungsi regulasi + transfer oksigen
Gambaran 20 asam amino
Tahu simbol-simbol
Struktur protein (NH3-C2)
‘isoelektrikal point’ switterion = 0
Protein yang berifat asam, bersifat basa, bersifa netral.
Kolmposisi protein: Glikoprotein, Lipoprotein, Metaloprotein
Biological Function:Enzim, Hormon, Neurotransmit, Toxin, Contractil Muscle, Storage protein (kasein), Protektif
protein
Insulin memiliki 51 asam amino
Asam amino aromatik
Asam amino yang tidak ada di protein, contoh D-Alanin = ada di dinding bakteri, Tiroksin = hormon tiroid, dsb
Jengkolid acid?
Kolagen, Elastin -> Strukturalnya
N-terminal = a.a + a.a -> ikatan peptida
C-terminal
Vasopresin
Insulin primer & sekunder
Helix; bentuknya termobil

Structure and Function Lipid

2) Role of lipids in the body
4) soluble in non-polar, either, chloroform, benzene
10) melting point
19) 9 kcal/g
22) major lipid, 40% arythrocyte membrane, 95% mithocondrial membrane, cardiolipin, a phosphoglyceride
25, 28
30) CNS white matter, sphingomielin glycosphingolipids, shingosine
32) membranes, sphingolipids no sugar
34, 35
38) gavcer’s disease, niemann- pick disease& tay-sachs
41
54) cholic, chenodeoxycholic, deoxycholic & lithocholic acids

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