PATHOPHYSIOLOGY OF ECTOPIC PREGNANCY

Etiology: Risk factors:

unknown Modifiable Non-modifiable
-smoking -age (35 years)

Smoking Implantation of developing Low β-hCG levels

blastocyst at the fallopian tube

Triggered a reaction Decidual breakdown in

increasing protein Cytotrophoblast is released the uterine cavity
(PROKR1) in the
fallopian tubes
Cytotrophoblast remodels
epithelial cells of fallopian tube Vaginal
PROKR 1 increases bleeding
risk of an egg to be
implanted outside the Growth of zygote
womb

Pressure and strain on the

Positive transvaginal external walls of fallopian tube
ultrasound

Nerve fibres stretch

Pelvic or
abdominal pain