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  • Discussion Topics, Chapter 57, Drugs Affecting Gastrointestinal Secretions

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    Lansoprazole decreases gastric acid production by blocking the final step in acid secretion. It differs from ranitidine in that ranitidine competitively inhibits histamine receptors to reduce acid production, while lansoprazole works via a different mechanism. There is a concern about a drug interaction between sucralfate and ciprofloxacin, as sucralfate can bind to other drugs in the gastrointestinal tract and prevent their absorption; key teaching points for patients taking sucralfate and lansoprazole include taking these drugs separately to avoid interactions.

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    Lansoprazole decreases gastric acid production by blocking the final step in acid secretion. It differs from ranitidine in that ranitidine competitively inhibits histamine receptors to reduce acid production, while lansoprazole works via a different mechanism. There is a concern about a drug interaction between sucralfate and ciprofloxacin, as sucralfate can bind to other drugs in the gastrointestinal tract and prevent their absorption; key teaching points for patients taking sucralfate and lansoprazole include taking these drugs separately to avoid interactions.

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    35 views1 page

    Discussion Topics, Chapter 57, Drugs Affecting Gastrointestinal Secretions

    Uploaded by

    clyde i am
    Lansoprazole decreases gastric acid production by blocking the final step in acid secretion. It differs from ranitidine in that ranitidine competitively inhibits histamine receptors to reduce acid production, while lansoprazole works via a different mechanism. There is a concern about a drug interaction between sucralfate and ciprofloxacin, as sucralfate can bind to other drugs in the gastrointestinal tract and prevent their absorption; key teaching points for patients taking sucralfate and lansoprazole include taking these drugs separately to avoid interactions.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
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    Discussion Topics, Chapter 57, Drugs Affecting Gastrointestinal

    Secretions

    Discussion Topics Learning


    Objective(s)
    1. Marcus has Zollinger-Ellison syndrome and will be placed on 2, 3, 4,
    lansoprazole (Prevacid) 30 mg orally daily to decrease the production of
    hydrochloric acid.
    a. How does lansoprazole decrease gastric acid production?
    b. What is the difference between the actions of lansoprazole and
    ranitidine?
    2. Miko has been receiving treatment for an eroded ulcer site from using 2, 3, 4, 5
    aspirin and is being treated with sucralfate (Carafate) and lansoprazole.
    She calls the clinic concerned because her general practitioner has given
    her ciprofloxacin for a urinary tract infection.
    a. What is the concern with a drug–drug interaction between
    sucralfate and ciprofloxacin?
    b. What are the key teaching points for patients taking sucralfate
    and lansoprazole?

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