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Altered Repolarization of the Myocardium

Release of Lysosomal Enzymes

Anaerobic Glycolysis Lactic Acid Production

Myocardial Irritability
ANGINA
Decreased Contractility
DYSRHYTHMIA

Ventricular Function

Preload CO

Blood Flow to Brain

LOSS OF CONS-CIOUSNESS

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 Enlargement of Thrombus www.NursesLabs.com

Occlusive Thrombus
WEAKNESS/FATIGUE (JULY 17-19)

Ischemia of Tissue in Region Supplied PALPITATIONS

by Artery

 O2
Coronary Blood Supply Less Than
Demand

 CO2 levels
MYOCARDIAL CELL DEATH (NECROSIS)

 Bld pH

DEEP & LABORED

BREATHING Stimulation of Sympathetic
NS

HR O2 need Afterload

Vasoconstriction
Epinephrine & Norepinephrine Production

HTN
BMR

ARRHYTHMIA Blood Supply to GI Tract

DIAPHORESIS N/V

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 PATHOPHYSIOLOGY OF ACUTE MI (BOOK-BASED)
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ACUTE MYOCARDIAL INFARCTION

.

MODIFIABLE FACTORS: NONMODIFIABLE FACTORS:

 Hypertension  (+) Family Hx of AMI

 Smoking  Aging
  levels of triglyceride, total cholesterol & LDL  Men and
 DM Postmenopausal Women
 Obesity
 Excessive intake of saturated fats, carbohydrates or
salt
 Sedentary lifestyle/physical inactivity
 Stress/Type A personality
 Drug Abuse

Change in the Condition of Plaque in the

Coronary Artery

Activation of Platelets
Rest
Pain
Platelet Aggregation, Adhesion, &
Buildup of Platelet Mass
Claudi-
cation
ATHERO-
SCLEROSIS THROMBOSIS

N/V
Release of Thromboplastin

Fainting
Platelet release Thromboxane A2, Serotonin,
Platelet Factors 3 & 4

Sweating
Coagulation and Vasospasm

Cool
extremities
Enlargement of Thrombus
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