TITLE DATE

Notes
HYPERSENSITIVITY KeAcTIONS
2emekally Sy&lem1S olechive
ult in Seveke
VoBechive mechanisms m a
amaoL ssLes Ond Lad dest
When ?
Sevee cawmos ccw hn J Immu
Sysle A0pondaol

Clasizicho
Losmbs md n e elsipiahaw:
e mmedinde apic0 anaph dathu
2 e Qukhed-dependona
T miua Cor e
el ed
m med iale otafopiu,o OmaphlLacic).
. e1 e l Semsitih anaMegie Neamsn Nakos
b t epocLe o Seci4Lamkigen
mhalian, niechiom
6 diseek Coma
he section u malated b Amiboel tes
nd pkaluceol b Lomedeat DLesR
bislam , 44Pt ase, tachidonat Cmd derivatives
by basepails gMo mst ol. .

Leadleea Jo AM
mglammalot-
L>me.olat
aponsSe
iHJn 'seconds
Second a
hhe
e cacian MaA -e:lke r 0 Sqsem\«

ymp lony fow mild lahiow Sudde -

 DATE
**********************s**

Notes

clea on Amaphylactic smock

hakmel LSal 'miove> epteneph Ad
a d mees od Cofeostetoids
C t h i st

Some Eiamples
as homav

2tlee cor1/aCZrviCis
cve
tleag
PmaphAlaxy

Cmtth
oC dependent
nafes Sensi t i o i , d u anbi beai_p duust
Ponse bind
Pafiént's cunC wrace
eea
s DEco)niz
he mbig/n
Cilles e meins1 i tse
Set amhge mn.aley led
he faliernS Co US) o
Some
eckio

mhae PoSs i bly A ol

a 1gM Onlt boch e s i n o

and
wa
Clanial a wa-
acfrvale hs
Dm Coleies hal elninahng Cells
s Coymple m e n t a c h a h o o t
Omhisens (whicw eue usualy
Piebenking e r n
lho )
meel(atod
ge n ë l i al e Silu one
a mel deaik
Ctlai Com)lex CeumsCS

7oion dako C
 **********"usu TITLE
DATE DATE
Notes

kame
do mmune halmolylie amaenala
_PDNiciow OmaeAla
amApw01 eae Ho
Hemeli,fic_eN's 2m o J mew hotn:
THee ÎMmUNE LOMPLE
In e dei Sen sihvi
olub|e mmmu emplexCAa onA
S OnR
Oniue
M CAmibocties) om
td omd Oka erocited m asio lssLe
eolyho SKm,kidma omd JoisJ.
Th m Om hmmum AOPOnse Qccodi
Qcuodirg
he claxia lemenA
Qhvio
o ke uachonn ros das devede
xames%
Camplex onOelomephsitA

SamtDY m IQ
AoKyLoslhlon
te N deSenáikiit
e hesienisihivi E n Calle dayed
e
deelo
muke ohw
Onhbod
mediateo bud Jalloj C Cu edialid
yesppnse
 DAL
****************

Notes

Comlad eeLmadi tu
empoo0 CVeritis
SPlomd 1u9»ekulosis.
b
HNPER sENSITIVT TH

hesesilyis so knoudn o
Iwmediole
e
omathlache hPeEesi

heFeac hion n a inoly.e Skim Oticala Cmd czema)

eye Conjunciuits) mooPhouy hino4khes

Ahmikis , ,bksnchofulmoncu issuas 081hma
anstoineshimal &od (skoënleai his )
he
Ihe eschio mcu CauR omg Sm{tla
hLoY minot imcomNONiece eatho
a k e ) S - 3 0 minles

amnRN:
ime o
SomeUm e) house
o- la hous)
mmadial esenStivil bmediatrd y
he Colu
eAsesikiv e e b t cau Jabophi
n d o omodited
Ja oghiow Ompluie
o deletu, nokaLil's Ovol e0sinsiils.
ops S sdioru s i demonkalek
A m cells md RoSinophils

.
 TITLE
DATE
Notes
Mechamis m
o Lactio Ivolves P etential
themethamism
PRoductio o in fomse CekainOnhRms hy
allagns)
lgEhas vcuu i ai ko aceplos om m
eus md Jaobily.
Saseqo oSuuhe Sana aleqem Uoss C
Cmks ke Ceu bound LgE amd iasesS e oe lea
atiowsA -phsma Col oqaicallr Gchve Susantes.
CLexS- Linkina o LaE S-Lenlo Tompodad
ih mast cu igeina Mast cCo deakanulation u
Pe.coded b ncecad CoPlasl Ca
P me
epiete CPto plemic Catt SuoS egamuation:
Cols mou iggescd k o s tmuli
Such
zerise
Cmohonal Skhes
chami'al e. pholoztapc dovelsima adium
Cuuum ionophoina ,oodeine ete)
napaulurins Ce5 Cqa , c a CSa te) ,

Deachos CR Mo1 nes8ewsikiv

SALMo alhou Ly d u e Le Sme S n lond
 DATE ITLE
*******************

Notes
TPE I HHPERSENSITLUTTY
Re hyeesentivitis alo knoun as Gtbloxu
hupesitivity mcl m aHteda yakiet 09
Omd issLul
he Qwiepm a e mDknaal endaeTO alkauah eraenous
Chalcols manlens)
Can a aad Ae I esemitivit
exaple
Dua Arduod h o a l i OMomta
-sRanuuoofeNa
hmdaocilapenla
Ho Lacahon kino mikoA ous
o Re 1 hesens tiutu i m a l l y madidad
m t i b o d l e so l
Camblemeril
oPhgpcae ad K_Collso aoblay a ale

a b Dagnosis
ncude deciow CiALlarino.

SuO nvalva Oa
KORntA mibody omd ompleme im Ja
LOMon loiops) nunuluoesCncao
HaPsen SiTINTJ
Hsd kmawn a mmUn Co e 'sea
OCcUS LSan ne Conplex (-Ab) ote

Umove Xon ck kim

Nojous dissu
l r e s ako daposited m
Owd am uch
-umwauummmu= wn ******
- ---*u-~------~**--** . - -
 DATE
TITLE

Notes
Kt dna
3oints
Lungr
SKin
a kes t 0
Immn Comple madion m
uloimune uceacs (eA)
esislence ineechion (Keati y vigs)
Repeated imhodahion ominicmakiek.

MECHAN*SM
Skp l:Lasge uanhities o Sousle Omkgtn-anibody
omplenes otm m J h e slood Omd au
no Cump)ele
amoved hy nnao hag
STEP micen- Omibod omplezes ogc
he pilasàes Jo dothalial A

SiePs:
Lhe c lasÍal Omplewed Vathuua dsading Sa Vaso
dilaation
SteP4 the comlenmerskeimg Od anhaaOwibod
emlex adatt daucot e uk l0a
SteP5i he eukocteA discdahae dto killimg.
lim
aaenb md pmesl masive Inslammakion Jhu Co
d o tissue clsai and hemotnay
Sslemi Lpus Ehmaosuus
oh iseax hatacleaizod he ptesen
cA do.cmtibodies, which o mun comnle ves uT
ukOaookiaems mal deposikek wrfhin dhe kicdm
lomDuli
 DATE T
****************

Notes
he sulim, l huPergewihivif, b sponsible
Jo ke omAulonephitis ( nemmalion l o a d .
CaneLa S s e l si n he glomcoa)..

e IV HPers.ensitivi
tuRe N hesensitiuit u k o ksan a s Ce
medialid 0 dehugd Re Ressensitiit
a heC lasial examle Sensitiit
erelin (MonlouneRoac ia
encion Caks uahouas R e inertium
O tiges e D d o Aules.culinj o esiono
chata cetized imushion Omd Qulhemo
R e N Pekensitivit muolval in tho h o n n
doimmuma. d intechiouddisesa
Tubercudosrs
Leasr
SlastomyLosiS
Hisoplasmssis
Poxoplmosis
LeishmaniaD
Gam ulomas due do ntectiow.s od doteign Gnitigen3
Amoth om delacd hpemGtiu is
Comact
heealk heay medol. etc.) i i uhich the
oa papual,
P VherBemkittviiy cam be clakliia
imdo theeeateati aekemdna_n h im
mdet Ame etical amo hidtologieal PLLR
 TITLE DATE

Notes
Mechami Sm
he mecbemikm imcludeg omphocteg amd
mamocyho
ame/ol macoohaag
Clotot Tcellk (Tc) Cau ieet clamoa9
uwMe.aL hel TCTHI). Cell Le0kake, etokie
tokimg
Which Actiyate ctetovic T celle, Akcsewit and
atiademmanacuk amd machopkaeS uuhieh
Caude he. bulk the damea
h delayeq bLLenkikiui Legiamk mam
Codain mnacHegNand a deu TCallk.

Dia9moCiS
Oamptie test in ila include delayed
Cubeouk enckion lA Momtouy te<tN
mUito keste Ao de.led huhek LeomLitiuft
imcud mita Aemic oponCe. neko uta hity
Acmd L-2 lnddction
kiCoLBeko idL am ahel mumo 6uppZLSSiNC
m am@ru.

-***********

----*----~~-*-----.