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Anti-Hypertensive Drugs
Prevention is always better than cure

Classification- KD Tripathi

1 2 3 4 5 6 7 8 9

ACE Angiotensin Calcium Channel Beta+Alfa Alfa Central

Diuretics Blocker Blocker Beta Blocker Blocker Blocker Sympatholytics Vasodilator
Inhibitor

Examples of above listed Class Thiazide Diuretics Channel is closed

Channel is Open
Thiazide- Hydrochlorothiazide, Chlorthiazide, Indapamide Increase Water & Sodium Excretion
High Ceiling- Furosemide
K+ Sparing- Spironelactone, Amiloride

Captopril, Enalapril, Linsopril, Perindopril, Short Term Effect Long Term Effect
Ramipril, Fosinopril etc.

Decrease Blood Volume Channel isDecrease

Open Sodium content in cell
Losartan, Candesartan, Irbesartan, Valsartan, Telmisartan 04

Verapamil, Diltiazem, Nifedipin, Felodipine,

Decrease cardiac output Decrease Calcium channel Blocker
Muscles sensitivity to vasopresser
Amlodipine, Lacidipine

Decrease Peripheral Resistance

Propranolol, Metoprolol, Atenolol Increase
01
Heart rate
Contractility
Labetalol, Carvedilol Conduction
Decrease Blood Pressure

Beta Receptor Blocker 05

Prazocin, Terazocin, Doxazosin, Angiotensinogen
Phentolamine, Phenoxybenzamine
Renin from Kidney Decrease output of Symp. Nervous system
Blood
Clonidine, Methyldopa Angiotensin I Increase vasodilatation of vascular muscle Pressure
(Inactive) Angiotensin II

Arteriolar- Hydralazine, Minoxidil, Diazoxide Decrease sod. And water retention

Arteriolar+ Venous- Sodium Nitropruside ACE Inhibitors Aldosterone Production

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