Name of drug Mechanism Indication Contraindication Nursing responsibilities

Generic name: SOLU-MEDROL Sterile Powder is Solu Medrol is a prescription medicine in systemic fungal Assessment
Methylprednisolon an anti-inflammatory used to treat the symptoms of Allergic infections and patients History: Infections; kidney
e glucocorticoid, which contains Conditions and Acute Exacerbations with known or liver disease,
Brand name: methylprednisolone sodium of Multiple sclerosis. hypersensitivity to the hypothyroidism,
Solu-Medrol succinate as the active product and its ulcerative colitis,
Functional class: ingredient. Methylprednisolone It can also treat the following: constituents. diverticulitis, active or
Corticosteroid sodium succinate, USP, is the  Allergic States latent peptic ulcer,
Chemical Class sodium succinate ester of  Dermatologic Diseases Serious infections except inflammatory bowel
Anti-inflamatory methylprednisolone, and it  Endocrine Disorders septic shock or disease, CHF,
steroid occurs as a white, or nearly  Gastrointestinal Diseases tuberculous meningitis; hypertension,
white, odorless hygroscopic,  Hematologic Disorders viral, fungal and thromboembolic
Dosage and route amorphous solid.  Miscellaneous tubercular skin lesions; disorders, osteoporosis,
125mg 0D P.O  Neoplastic Diseases admin of live virus seizure disorders,
 Ophthalmic Diseases vaccines. Preparations diabetes mellitus;
 Rheumatic Disorders containing benzyl alcohol pregnancy; lactation
preservative are
contraindicated in Physical: Weight, T,
infants. reflexes and grip
strength, affect and
orientation, P, BP,
peripheral perfusion
prominence of superficial
veins, R and adventitious
sounds, serum
electrolytes, blood
glucose
https://www.drugs.com/cdi/solu-medrol.html
Name of drug Mechanism
Generic name: The precise mechanism by
which hydroxychloroquine
hydroxychloroquine
exhibits activity against
Trade name: Plasmodium is not known.
Hydroxychloroquine is a
Plaquenil
weak base and may exert its
Functional class: effect by concentrating in
the acid vesicles of the
Disease-modifying antirheumatic
parasite and inhibiting
drugs (DMARDs)
polymerization of heme. It
Dosage and route: can also inhibit certain
enzymes by its interaction
200mg O.D P.O with DNA.
Indication
PLAQUENIL is indicated for
the treatment of acute and
chronic rheumatoid arthritis
in adults. It can also treat
Systemic Lupus
Erythematosus and Chronic
Discoid Lupus
Erythematosus
Contraindication Nursing responsibilities
PLAQUENIL is not Assess deep tendon
recommended for: reflexes periodically to
determine muscle
 Treatment of
weakness. Therapy may
malaria by
be discontinued should
chloroquine or
hydroxychloroquine- this occur.
resistant strains of Monitor ECG for
Plasmodium species
cardiomyopathy and
 Prophylaxis of
QT prolongation
malaria in
periodically during
geographic areas
therapy.
where chloroquine
resistance occurs. Monitor for signs and
 Hypersensitivity to symptoms of DRESS
hydroxychloroquine (fever, rash,
or chloroquine.
lymphadenopathy,
and/or facial swelling,
 Previous visual
associated with
damage from
hydroxychloroquine involvement of other
or chloroquine organ systems
(hepatitis, nephritis,
hematologic
abnormalities,
myocarditis, myositis)
during therapy. May
resemble an acute viral
infection. Eosinophilia
is often present.

https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Drug-Guide/51386/all/hydroxychloroquine
Name of drug Mechanism
Generic name: Hypertonic solutions are
those that have an
Lactated Ranger’s in 5% Dextrose
effective osmolarity greater
injection
than the body fluids. This
Trade name pulls the fluid into the
vascular by osmosis
Lactated Ranger’s in 5% Dextrose resulting in an increase
vascular volume. It raises
intravascular osmotic
Dosage and route
pressure and provides fluid,
D5LR 1L @ 20 gtts/min IV electrolytes and calories for
energy.
https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=190da07e-a616-46e6-b4e5-1c0ba39306e5
Indication
The Dextrose 5% in
Lactated Ringers Solution
(D5LRS) is useful for daily
maintenance of body fluids
and nutrition, and for
rehydration. Nonpyrogenic,
parenteral fluid, electrolyte
and nutrient replenisher
Contraindication
This solution is
contraindicated where the
administration of sodium,
potassium, calcium,
chloride or lactate could be
clinically detrimental.
Lactate administration is
contraindicated in severe
metabolic acidosis or
alkalosis, and in severe liver
disease or anoxic states
which affect lactate
metabolism.
Solutions containing
dextrose may be
contraindicated in patients
with hypersensitivity to
corn products.
Discontinue therapy if
signs occur.
Nursing responsibilities
 Do not administer
unless solution is
clear and container
is undamaged.
 Check vital signs
frequently.
 Report adverse
reactions.
 Monitor fluid
intake and output
and weight
carefully.