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Integración Metabólica - Bioquímica
Integración Metabólica - Bioquímica
The glucose generated in the body can only An oxidative process in any tissue where it
enter the cells thanks to glucose transporters produces ATP and NADPH. The ATP, an es-
(GLUT). Organs such as the brain and eryth- sential molecule in the process of energy
rocyte can enter glucose since these trans- generation and other metabolic processes, is
porters do not need insulin as an activator to generated by glycolysis and the Krebs Cycle.
enter it and then, thanks to Hexokinase, they NADPH as an electron donor for the reduc-
fix the glucose for its use. Others, such as the tion process is very important for catabolic
muscles and adipocytes, cannot enter gluco- and anabolic processes.
se since they need insulin as a ligand. A very
important case to mention is that of the liver:
although it is an independent insulin, the A non-oxidative process that occurs in the
coupling of glucose does not occur very well muscles and in the liver to a greater extent.
since the kinase that generates this, Glucoki- This process instead of generating ATP from
nase, is in very low quantity due to lack of glucose, stores it in small capsules called
insulin, so glucose enters and leaves the liver glycogen for future use where food is not
without generating any change. available.
On the other hand, in the postprandial state, All these processes are very important for the
in the state generated after ingesting food, proper functioning of the human body and
the insulin is triggered at the same time that other living beings.
the exit of lipids, proteins and glucose by the
glycogen is closed.
Link to open the diagram :
https://www.goconqr.com/es-ES/flowchart/
25550427/Integraci-n-Metab-lica