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  • LD 50 For SLS Is 1288 MG / KG: MACO of SLS 128860SF BS / MDD

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    Ali Kureishi
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    This document provides a formula to calculate the maximum allowable concentration (MACO) of sodium lauryl sulfate (SLS) for a product. The MACO of SLS is calculated based on the lethal dose 50% (LD 50), a safety factor, the smallest batch size, and maximum daily dose of the product. This formula allows one to determine the limit for SLS concentration through these parameters.

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    Maco for Sls

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    This document provides a formula to calculate the maximum allowable concentration (MACO) of sodium lauryl sulfate (SLS) for a product. The MACO of SLS is calculated based on the lethal dose 50% (LD 50), a safety factor, the smallest batch size, and maximum daily dose of the product. This formula allows one to determine the limit for SLS concentration through these parameters.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
    14 views1 page

    LD 50 For SLS Is 1288 MG / KG: MACO of SLS 128860SF BS / MDD

    Uploaded by

    Ali Kureishi
    This document provides a formula to calculate the maximum allowable concentration (MACO) of sodium lauryl sulfate (SLS) for a product. The MACO of SLS is calculated based on the lethal dose 50% (LD 50), a safety factor, the smallest batch size, and maximum daily dose of the product. This formula allows one to determine the limit for SLS concentration through these parameters.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 1

    MACO for SLS:

    LD 50 for SLS is 1288 mg / kg

    MACO of SLS = 128860SF*BS / MDD

    Where as, 60 = Normal human body weight


    SF = Safety Factor (for solid orals 1/100 to 1/1000)
    BS = Smallest batch size of Product B
    MDD = Maximum Daily Dose of Product B

    U can calculate the limit for SLS thru this.

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