ATLAS OF HUROPATH

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02 Thyroid Papillary carcinoma

04 Thyroid Adenomatous hyperplasia
05 Thyroid Hashimoto’s disease
06 Thyroid Hürthle cell tumor
07 Thyroid Follicular neoplasia
08 Thyroid Cystic change

FNA
FNA

Thyroid Papillary carcinoma

[Cytologic Criteria]
Nuclear grooves and intranuclear cytoplasmic inclusions
Nuclear molding, crowding and overlapping, marked nuclear
enlargement
Coarse chromatin
x40

Cytoplasmic inclusions Cytoplasmic inclusions

2 CelltraZone Co., Ltd.

FNA

Thyroid Papillary carcinoma

[Cytologic Criteria]
Hypercellularity with many cohesive sheets and clusters of
atypical follicular cells
Enlarged follicular cells with irregular nuclear membranes
Small but prominent and often eosinophilic nucleoli
x40

3 CelltraZone Co., Ltd.

FNA

Thyroid Adenomatous hyperplasia

[Cytologic Criteria]
Mild to moderately atypical cells
Pseudopapillae and cellular group may be present
x40 Colloid

4 CelltraZone Co., Ltd.

FNA

Thyroid Hashimoto’s disease

[Cytologic Criteria]
Amphophilic granular cytoplasm and a large vesicular nucleus
Polygonal cells with distinct cell borders
Pseudofiber, Plasma cells, Small lymphocyte and large
lymphocyte
x40

Pseudofiber

Plasma cell

Small lymphocyte Hürthle cell

Large lymphocyte

5 CelltraZone Co., Ltd.

FNA

Thyroid Hürthle cell tumor

[Cytologic Criteria]
Amphophilic granular cytoplasm and a large vesicular nucleus
Polygonal cells with distinct cell borders
The cytoplasm of Hürthle cell tumor is characterized by an
x40 amphophilic granular nature

6 CelltraZone Co., Ltd.

FNA

Thyroid Follicular Neoplasia

[Cytologic Criteria]
x40 Microfolicles with atypical numerous follicular cells

Microfolicles Microfolicles

7 CelltraZone Co., Ltd.

FNA

Thyroid Cystic change

[Cytologic Criteria]
Cystic fluid with colloidophages
x40 Colloidophages including colloid materials and hemosiderin

8 CelltraZone Co., Ltd.

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