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TECHNO BYTES

Accuracy of 3-dimensional printed


dental models reconstructed from
digital intraoral impressions
€ns Currier,a Onur Kadioglu,a and J. Peter Kierlb
Gregory B. Brown,a G. Fra
Oklahoma City, Okla

Introduction: A rapidly advancing digital technology in orthodontics is 3-dimensional (3D) modeling and
printing, prompting a transition from a more traditional clinical workflow toward an almost exclusively digital
format. There is limited literature on the accuracy of the 3D printed dental models. The aim of this study was
to assess the accuracy of 2 types of 3D printing techniques. Methods: Digital and alginate impressions of the
oral environment were collected from 30 patients. Subsequently, digital impressions were used to print 3D
models using digital light processing (DLP) and polyjet printing techniques, and alginate impressions were
poured up in stone. Measurements for the 3 model types (digital, DLP, and polyjet) were compared with the stone
models. Tooth measurements (first molar to first molar) included mesiodistal (crown width) and incisal/occlusal-
gingival (crown height). Arch measurements included arch depth and intercanine and intermolar widths.
Intraobserver reliability of the repeated measurement error was assessed using intraclass correlation
coefficients. Results: The intraclass correlation coefficients were high for all recorded measurements, indicating
that all measurements on all model types were highly reproducible. There were high degrees of agreement be-
tween all sets of models and all measurements, with the exception of the crown height measurements between
the stone and DLP models, where the mean difference was statistically significant. Conclusions: Both the DLP
and polyjet printers produced clinically acceptable models and should be considered viable options for clinical
application. (Am J Orthod Dentofacial Orthop 2018;154:733-9)

T
he evolution of digital technologies in orthodon- However, the current digital workflow in orthodontics
tics has influenced the traditional clinical work- predominantly relies on digital impressions directly
flow toward an almost exclusively digital acquired from the oral environment with an intraoral
format.1,2 One of the most rapidly advancing digital scanner.11,12 This inconsistency between research and
technologies is 3-dimensional (3D) modeling that uses practice demonstrates a need to test the accuracy of
scanned data or digital impressions to create digital the latter, as has been done for the former.
models.3-6 These digital impressions can be acquired The advantages of digital models include no physical
either indirectly from a patient's models or impressions storage requirement; instant accessibility; ability to do
using a desktop or intraoral scanner, or directly from digital diagnostic or treatment simulations; positive pa-
the patient's oral cavity using an intraoral scanner. tient perceptions; ability to immediately send to an
The authors of most previous scanner studies have outside laboratory; no risk of breakage, wear, degrada-
evaluated the accuracy of digital models produced tion, or loss; and an overall improved continuity of
from indirectly acquired digital impressions.1,5,7-10 care; in addition, digital models are less labor inten-
sive.5,13-15 Although the advantages are numerous,
digital models come with at least 1 important
a
disadvantage. Without a physical model, treatment
Department of Orthodontics, College of Dentistry, University of Oklahoma
Health Sciences Center, Oklahoma City. planning for complex cases in a teaching environment
b
Department of Orthodontics, College of Dentistry, University of Oklahoma can be challenging, and a physical model is still
Health Sciences Center, Oklahoma City; private practice, Edmond, Okla. required for appliance fabrication.2,16
All authors have completed and submitted the ICMJE Form for Disclosure of Po-
tential Conflicts of Interest, and none were reported. Rapid prototyping provides a solution to this limita-
Address correspondence to: Onur Kadioglu, 1201 N Stonewall Ave, Room 400, tion by producing a physical replica of a digital model. In
Oklahoma City, OK 73117; e-mail, onur-kadioglu@ouhsc.edu. orthodontics, the most common rapid prototyping tech-
Submitted, September 2017; revised and accepted, June 2018.
0889-5406/$36.00 nique is 3D printing.11,16 Two of the most common 3D
https://doi.org/10.1016/j.ajodo.2018.06.009 techniques in the marketplace today are digital light
733
734 Brown et al

processing (DLP) printing and polyjet printing.17 Both Thirty patients were randomly selected from a pool of
techniques use additive manufacturing to fabricate a retention patients who received treatment at the
3D model, layer by layer, based on a digital model.18-20 University of Oklahoma Graduate Orthodontic Clinic. A
DLP printing uses a conventional light source such as an patient was considered in retention if the appliances
arc lamp, liquid crystal display panel, or projection had been removed 6 to 18 months before records
source to cure the surface layer of a vat of photo- collection for this study. The inclusion criteria were
polymerizing resin in a specific orientation based on a (1) orthodontic treatment at the Graduate Orthodontic
digital model. Polyjet printing uses jet heads that spray Clinic, (2) complete comprehensive treatment, and
or jet the resin in the desired areas. As the jet heads (3) all permanent teeth, first molar to first molar, in
make subsequent passes, each sprayed layer is cured us- both dental arches.
ing an ultraviolet light source. In both printing tech- Both the digital and alginate impressions were taken
niques, the initial layer of resin is cured onto a build at the 1-year retention appointment for all patients. Dig-
platform or a build plate, with each subsequent layer ital impressions were recorded using a chairside intraoral
cured directly to the previous layer of cured resin in scanner (Omnicam; Dentsply Sirona, York, Pa). Jeltrate
the z-axis to create a 3D object. The build plate lowers fast-set alginate (Sirona Dentsply) was used to make im-
at a predetermined increment, which determines the pressions with stock impression trays. The alginate was
thickness of each layer of resin that is cured.20,21 The mixed using Cadco Alginator II electric mixer (Patterson
process of producing a 3D printed model from a Dental, St Paul, Minn). Impressions were poured with
digital impression is summarized in Figure 1. white ISO type 3 orthodontic model stone (Whip Mix,
There is limited literature on the accuracy of 3D Louisville, Ky) and mixed using a Vac-U-Mixer (Whip
printed dental models. Most previous studies have Mix). All aspects of record collection followed the
concluded that 3D printed models are reasonably accu- manufacturers' recommendations. Alginate impressions
rate and may be suitable for clinical use.16,22,23 were poured with dental stone within 24 hours.
However, these studies have had limited sample sizes, All digital models generated with the intraoral scan-
did not measure arch dimensions, and used digital ner were converted to .STL file format using additional
impressions that were not recorded directly from the 3D imaging software (Dolphin Imaging and Manage-
patient. The authors of a recent study investigated ment Solutions, Chatsworth, Calif). The .STL files were
the accuracy of 3D printed models produced from cleaned and prepared for 3D printing using Netfabb ad-
digital models acquired from the oral environment ditive manufacturing and design software (Autodesk,
and measured multiple arch dimensions.11 However, San Rafael, Calif). The prepared .STL file for each patient
they used a limited sample size and did not compare was printed using two 3D printing techniques: DLP
the printed models with stone models, which have (Juell 3D Flash OC; Park Dental Research, New York,
been established as the gold standard in previous NY) and polyjet (Objet Eden 260VS; Statasys, Eden Prai-
studies.16,17,22,23 rie, Minn). Models were printed successively from their
The accuracy of a 3D printer must be confirmed respective printers. The workflow for collecting patient
through research for it to be mainstreamed into the or- records and producing study models is summarized in
thodontic specialty. Therefore, this study was designed Figure 2. All 3D printed models were printed as solid
to assess the accuracy of 3D digital models and printed models with a horseshoe-shaped base and in the hori-
models in the context of a commonly used digital work- zontal position. Figure 3 illustrates both 3D printed
flow in orthodontic practice. model types.
A total of 240 maxillary and mandibular arches were
MATERIAL AND METHODS measured with 60 arches from each of the 4 model
Ethical approval for this study was obtained from the types (stone, digital, DLP, and polyjet). All measure-
Institutional Review Board for the Protection of Human ments of the physical models were obtained using a
Subjects at the University of Oklahoma (Institutional Re- calibrated digital caliper (Orthopli, Philadelphia, Pa)
view Board number 7132; reference number 655134) in and measured to the nearest 0.01 mm directly from
Oklahoma City. the models, with the exception of arch depth, which
A power analysis was done based on a similar precur- was measured using the digital caliper from a 1:1 scale
sor study.16 A total of 22 patients were required for this photocopy of the occlusal view. Measurements of the
study to oftain an 80% probability of generating 95% digital models were all obtained using Dolphin Imaging
confidence intervals with margins of error less than software. For all teeth, first molar to first molar, in both
0.1 mm for tooth measurements and 0.25 mm for arch arches, the tooth measurements included (1) the mesio-
dimension measurements. distal widths from point contact to point contact

November 2018  Vol 154  Issue 5 American Journal of Orthodontics and Dentofacial Orthopedics
Brown et al 735

Fig 1. The process of producing a 3D printed model.

Fig 2. Study flow chart.

(crown width) and (2) the incisal/occlusal-gingival Statistical analysis


heights from gingival zenith to cusp tip or incisal Bland-Altman plots24 were used to evaluate the
edge (crown height). For both arches, arch dimension agreement of the crown width, crown height, interca-
measurements included (1) intercanine width from nine, intermolar, and arch depth measurements between
cusp tip to cusp tip, (2) intermolar width from the stone, digital, DLP, and polyjet models. Table I lists
mesiolingual cusp tip to mesiolingual cusp tip, and the comparisons and what each evaluated. Ten percent
(3) arch depth from the midline of the central incisors of each model type was measured a second time with
to a perpendicular line crossing the mesial contact of a 2-week interval between measurements. Intraclass
the first molars. Crown height measurements for the correlation coefficients (ICC) were used to assess the in-
digital models were not possible because of the traobserver reliability of the repeated measurement
inability of the software to replicate the same measure- errors.
ment technique used on the physical models. All other
digital measurements were collected using the same
measurement technique as on the physical models. RESULTS
Three calibrated researchers measured and recorded A total of 5760 tooth measurements were recorded
the data, with 1 researcher measuring either crown from 240 maxillary and mandibular arches. An addi-
width, crown height, or arch dimensions for all models. tional 720 arch dimension measurements were recorded

American Journal of Orthodontics and Dentofacial Orthopedics November 2018  Vol 154  Issue 5
736 Brown et al

Fig 3. Three-dimensional printed model types: A, polyjet; B, DLP.

Table I. Comparisons of models to evaluate accuracy Table II. Repeated measurement mean errors (mm)

Comparison Evaluation Crown Crown Intercanine Intermolar


Stone and digital Clinical accuracy of digital impression Model width height width width Arch depth
Digital and DLP Accuracy of the DLP printing process Stone 0.03 0.04 0.07 0.08 0.06
Digital and polyjet Accuracy of the polyjet printing process Digital 0.04 NA* 0.07 0.08 0.04
Stone and DLP Clinical accuracy of DLP printer DLP 0.03 0.05 0.07 0.07 0.06
Stone and polyjet Clinical accuracy of polyjet printer Polyjet 0.02 0.07 0.08 0.08 0.06

*NA indicates that repeated measurement mean errors were not


calculated due to the inability to replicate the same measuring tech-
from the same sets of arches, for a total of 6480 mea- nique digitally as was done physically with a digital caliper.
surements. The ICC values were high for all recorded
measurements based on repeated measurement error,
significantly lower than the mean crown height mea-
indicating that all measurements on all model types
were highly reproducible (Table II). surements for stone models by 0.29 mm, suggesting
that the DLP printed models underestimated the true
The Bland-Altman plots24 demonstrated high
crown height dimensions.
agreement between (1) stone and digital models for
crown width, intercanine, intermolar, and arch depth
DISCUSSION
measurements; (2) stone and polyjet models for all
measurements; and (3) digital and polyjet models for The accuracy of two 3D printing techniques
crown width, intercanine, intermolar, and arch depth commonly used in orthodontics was assessed in this
measurements (Table III). The limits of agreement are study. A unique aspect of this research was that the 3D
given in Table III. In addition, the Bland-Altman plots printed models were produced from digital impressions
showed high agreement between stone and DLP acquired directly from the oral environment and then
models and between digital and DLP models for crown compared with stone models. The importance of this
width, intercanine, intermolar, and arch depth mea- comparison was the ability to evaluate the entire digital
surements. However, the mean difference was statisti- workflow from directly acquiring a digital impression
cally significant for crown height measurements from the oral environment to producing a 3D printed
between stone and DLP models. The mean crown model of it. To our knowledge, no previous studies
height measurements of the DLP models were have made such a comparison that would evaluate the

November 2018  Vol 154  Issue 5 American Journal of Orthodontics and Dentofacial Orthopedics
Brown et al 737

variables not otherwise controlled, such as saliva,


Table III. Agreement between the different model
tongue, lips, cheeks, or movement. The authors of the
measurements (mm)
only study that has assessed the accuracy of an intraoral
Mean Limits of scanner under clinical conditions suggested that oral
Measurement difference (mm) agreement (mm) conditions do affect the accuracy.12 In addition to
Stone (1) vs digital (2) comparing 3D printed models produced from two 3D
Crown width 0.06 –0.27 to 0.38
Crown height NA* NA*
printed techniques with stone models, we evaluated
Intercanine 0.03 –0.41 to 0.47 the accuracy between the digital models and the 3D
Intermolar 0.09 –0.54 to 0.71 printed models. This comparison solely assessed how ac-
Arch depth 0.11 –0.41 to 0.63 curate the 3D printing techniques were by eliminating
Digital (1) vs DLP (2) variables introduced during acquisition of the digital im-
Crown width 0.01 –0.30 to 0.32
Crown height NA* NA*
pressions. All previous studies investigating the accuracy
Intercanine –0.09 –0.64 to 0.46 of 3D printed dental models have expressed the need for
Intermolar –0.15 –0.72 to 0.41 studies with larger sample sizes. We used a sample 3
Arch depth 0.02 –0.48 to 0.52 times larger than the next largest study. With the excep-
Digital (1) vs polyjet (2) tion of 2 previous studies, all failed to assess the accuracy
Crown width –0.01 –0.36 to 0.35
Crown height NA* NA*
of arch dimension measurements and focused only on
Intercanine –0.06 –0.55 to 0.42 measurements specifically related to the teeth.11,14
Intermolar –0.10 –0.63 to 0.44 Arch dimension measurements may not be critical if
Arch depth 0.01 –0.49 to 0.50 the sole purpose of a model is to be used for Bolton
Stone (1) vs DLP (2) analysis, as previous studies have done. However, to
Crown width 0.06 –0.20 to 0.43
Crown height –0.29 –1.04 to 0.46
maximize the use of a 3D printed model, arch
Intercanine –0.06 –0.61 to 0.49 dimension measurements must also be evaluated
Intermolar –0.07 –0.61 to 0.47 because these measurements are critical if a 3D printed
Arch depth 0.13 –0.37 to 0.63 model will be used to produce an appliance or aligner,
Stone (1) vs polyjet (2) as many orthodontists are already doing in practice.
Crown width 0.05 –0.33 to 0.43
Crown height 0.08 –0.57 to 0.73
Both 3D printing techniques used in this study, DLP
Intercanine –0.04 –0.48 to 0.41 and polyjet, have been documented to provide excellent
Intermolar –0.01 –0.51 to 0.49 accuracy and surface finish.19-21 A number of previous
Arch depth 0.11 –0.32 to 0.55 studies have shown that the polyjet printing technique
The mean difference equals the (2) measurements minus the (1) has produced more accurate models compared with
measurements where (1) represents the gold standard. Thus, a pos- other printing methods.11,16 In this study, the DLP and
itive value represents on average that the (2) measurements are over- polyjet printed models showed a similar mean
estimated compared with the (1) measurements. Conversely, a
negative mean difference represents on average that the (2) mea-
difference and had similar limits of agreement when
surements are underestimated compared with the (1) measurements. compared with a stone model for all recorded
*NA indicates that agreement between model measurement assess- measurements, with the exception of the crown height
ments were not possible due to the inability to replicate the same measurement (z-axis). The agreement between polyjet
measuring technique digitally as was done physically with a digital and stone models was high for this measurement,
caliper.
whereas the agreement between DLP and stone models
was low, with a mean difference of 0.29 mm and
accuracy of this technology the way it is currently being limits of agreement from –1.04 to 0.46 mm.
clinically implemented. The DLP printer used here prints to a minimum thick-
Only 1 study has evaluated the application of using ness of 50 mm. The polyjet printer used here prints to a
digital impressions to produce 3D printed models that minimum thickness of 16 mm. Both printers were set to
were directly acquired from the patient.11 However, the their most accurate settings. Accuracy and surface finish
method did not include stone models. In our opinion, of a 3D printer are limited by the thickness of the layers
including stone and digital model comparisons provides that are successively added in the z-axis, with thicker
a more complete picture when testing for accuracy. Tak- layers leading to greater inaccuracy.17,19,21 The
ing digital impressions from the oral environment variation in thickness of the layers that build the
without stone models, while lacking data on the accu- model in the z-axis may explain the variations found
racy of the scanner under clinical conditions, would in the crown height measurements in this study. It
make it difficult to evaluate whether any errors in the ac- would be expected that the polyjet printer, which
curacy of the 3D printing technique were due to prints thinner layers in the z-axis, ought to produce

American Journal of Orthodontics and Dentofacial Orthopedics November 2018  Vol 154  Issue 5
738 Brown et al

more accurate models. The variation in the accuracy of Other considerations for future studies could focus
crown height measurements between the DLP and on the accuracy of 3D printing models in vertical orien-
polyjet printed models when compared with stone tations, allowing for additional models to be printed at a
models could also partially be explained by the fact given time, testing hollow formats that require less resin
that the polyjet printing technique does not require in the printing process, and testing in high-speed set-
postcuring once the model is fully printed. This may tings that print with thicker layers in the z-axis.
lead to greater stability during printing.20 DLP printed In this study, we assessed (1) the accuracy of an in-
models require postcuring, which can lead to additional traoral scanner under clinical conditions, (2) the accu-
shrinking of the resin. The shrinkage related to postcur- racy of two 3D printed techniques, and (3) the
ing has the greatest impact on the z-axis.17 accuracy of the combination of (1) and (2), which as-
Few studies have defined or established a range of er- sessed the clinical application of acquiring a digital
ror that is considered to be clinically acceptable. Of impression under clinical conditions and 3D printing a
those, 0.20 to 0.50 mm has been considered an accept- physical model.
able range for clinical accuracy.14,16,25-28 The mean
difference of 0.29 mm between the DLP and stone CONCLUSIONS
models, although statistically significant, is in the
range of clinically acceptable norms for 5 of the 6 1. Both the DLP and polyjet printers produced clini-
studies that have discussed this topic and fell only cally acceptable models with high accuracy that
0.09 mm outside the strictest recommended value to may allow them to serve as a replacement for stone
be considered clinically accurate. Given the models and to be considered viable options for clin-
recommendations of previous studies and the accuracy ical applications.
produced by the 3D printing techniques used here, 2. The polyjet printer produced models with clinically
both the DLP and polyjet printers produced clinically acceptable accuracy for all recorded measurements.
acceptable models and could be considered viable Compared with the DLP printer, the polyjet pro-
options for clinical applications. duced models with closer accuracy to the stone
Crown height measurements for digital models were models.
not possible because of the inability to replicate the 3. The mean difference between crown height mea-
same measuring technique digitally as was done phys- surements for the DLP and stone models was statis-
ically with a digital caliper. In a future study, it would tically significant in this study, but the mean
be ideal to compare the crown height measurements of differences were within a clinically acceptable
the digital model with both stone and printed models. range.
For this study, we assumed that the statistically signif-
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