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Technical Training - B.pharm - 3
Technical Training - B.pharm - 3
Industrial Training
Daily Report
Name of Expert, Affiliation: Dr. Ramnath (Associate Research Director) Reliance Life Sciences
and Mr. Sameer Shaikh (Research Leader) Reliance Life Sciences
• Introduction to the
Industry
• Drug Discovery
• Drug Development
• Medical Affairs
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, Mumbai 1
B.Pharm. Industrial Training
Daily Report
talked about the pharmaceutical
industries history.
• Physicians
• Payers
• Corporate account
• Government insurance
program
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, Mumbai 2
B.Pharm. Industrial Training
Daily Report
• Pharmacy benefit
managers
• Exploratory discovery
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, Mumbai 3
B.Pharm. Industrial Training
Daily Report
about the clinical testing phases
i.e., phase 1, 2, 3 etc.
• Clinical research
• Market
• Direct information
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, Mumbai 4
B.Pharm. Industrial Training
Daily Report
• Availability of controls
• Controlled modification
of variables
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, Mumbai 5
B.Pharm. Industrial Training
Daily Report
• Normal animal models
which include healthy
normal animals.
• Spontaneous models
• Induced models. It
includes experimentally
induced models.
• Transgenic models
• Orphan models. It is a
model which contains
diseases not found in
humans.
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, Mumbai 6
B.Pharm. Industrial Training
Daily Report
This session was based on What is the
“PRECLINICAL RESEARCH IN difference between
INDUSTRY.” PK-PD,
Toxicokinetics &
Firstly, we learned about the Toxicodynamics?
Process of drug development
For the approval,
and need of animals testing. What kind of
considerations are
Then we discussed about the
important?
objective of using animals which
included:
➢ To improve understanding
about human biology using
an animal model.
➢ Helps study various
diseases.
➢ To test potentials
treatments.
➢ To ensure safety of the
people & the environment.
Then we discussed about the
various types of animals used.
Then we gained knowledge about
the preclinical research which
included R&D and Toxicology.
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, Mumbai 7
B.Pharm. Industrial Training
Daily Report
➢ Routes of exposure
➢ Frequency of exposure
➢ Duration of exposure
• Activation of Toxicology
pathway: Means to expose any
chemical/drug to the test
system.
1. Exposure
2. Tissue dose
3. Biologic interaction
4. Perturbation
5. Early cellular changes-
depends on the substance
or the lethality of the
substance
6. Cell injury
7. Morbidity
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, Mumbai 8
B.Pharm. Industrial Training
Daily Report
Its vision includes:
• Reaching People and Touching
Lives Globally as A Leading
Provider of Valued Medicines.
• Mission:
• Leverage their people, expertise
and networks to address the
needs of the communities that
they serve and thereby catalyze
overall development.
• Strongly believe that business
and responsibility go hand-in-
hand.
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM’s NMIMS, Mumbai 9