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HANGZHOU ZHONGBAO IMP AND EXP. CORP., LTD.

13F/E 8 BUILDING, WESTPORT NEW TERRITORIES, NO 206 ZHENHUA ROAD,
HANGZHOU, CHINA.
TEL: 86-571-85811826 FAX: 86-571-87357766
WWW.ZHONGBAOCHEMICAL.COM
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Certificate of Analysis Consistent Quality

Product Name CLOMIPRAMINE HYDROCHLORIDE Analysis basis BP

Batch Number 20180111 Date of Mfg. 2018-01-11 Date of Expiry 2021-01-10
Quantity 25 kgs Packages Size 25kg/drum
Keep the container tightly closed in a dry and well-ventilated indoor area, away
Storage condition
from light or heat or moisture
ITEM SPECIFICATION RESULTS
Appearance White or slight yellow, crystalline powder, White crystalline powder
slightly hygroscopic
Solubility Freely soluble in water and in methylene Conforms
chloride, soluble in alcohol
Identification A: Melting point: 191-195℃ 192-193℃
B: Infrared absorption spectrophotometry Conforms
C,D,E: Conforms Conforms
Appearance of solution Solution S is clear and not more intensely Conforms
coloured than reference solution Y5
PH 3.5-5.0 4.1
Related substance
Impurity B Not more than 1.0% 0.25%
Impurity C Not more than 0.2% 0.1%
Impurity D Not more than 0.2% 0.07%
Impurity F Not more than 0.1% 0.07%
Any other impurities Not more than 0.1% Conforms
Total of other impurities Not more than 0.2% 0.12%
Total of impurities Not more than 1.0% 0.61%
Loss on drying Not more than 0.5% 0.3%
Heavy metals Not more than 20ppm <20ppm
Sulphated ash Not more than 0.1% 0.06%
Assay 99.0-101.0% 99.5%

Conclusion: The above results comply with BP.

Analysts: Gezheng Checker Ren Yuehua Supervisor Chen Jinguo

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