Hospital & Clinical Pharmacy (0816)

Important questions for Practical Oral and synopsis:

1.Define Hospital Pharmacy.

2.Define Clinical Pharmacy.
3.What is transfusion fluid?
4.Write uses of transfusion fluid.
5.What is isotonicity?
6.Define hypertonic & hypotonic solution.
7.What will happen if tonicity is not adjusted?
8.What are the quality control tests for transfusion fluid?
9.Why do large volume parenteral not contain any
preservatives?
10. Are aseptic technique & sterilization equal?
11. Define aseptic technique.
12. Name the filters used in laminar air flow.
13. Define intravenous infusions.
14. Write components of hot air oven.
15. Write components of autoclave.
16. Write full form of HEPA.
17. Write sterilization Temperature, pressure & time for
autoclave.
18. Write sterilization Temperature, time for hot air oven.
19. Define water for injection.
20. Write applications of flame photometer.
21. What is potable water?
22. What is purified water?
23. What is sterile water for injection?
24. What are different type of glass used as container for
pharmaceutical use?
25. Write the limitation of glass container for transfusion
fluid.
26. Write advantages of plastic as container for parenteral
use.
27. Why should water for injection be used immediately for
preparation of transfusion fluid?
28. Why anhydrous form of dextrose is used in preparation
of transfusion fluid?
29. Define pyrogen?
30. Define sterilization
31. Enlist the different methods of sterilization.
32. Write full form of LAL.
33. What are the importance of pyrogen test?
34. Name three parts of flame photometer.
35. Define achromicity.
36. What is hydrolytic resistance test?
37. Write use of powder glass test.
38. Write characteristics of ideal container.
39. Write two additives of plastic container.
40. What are antioxidants?
41. Write category of dextrose intravenous infusion.
42. Write full form of LVP & SVP.
43. What is caramelization?
44. Write category of sodium chloride intravenous
infusion.
45. Write composition of compound sodium chloride
intravenous infusion.
1. The moist heat sterilization method includes:
a. Hot air oven
b. Autoclave
c. Incubator
d. LAF

2. The dry heat sterilization method includes:

a. Hot air oven
b. Autoclave
c. Incubator
d. LAF

3. Full form LAF

a. Laminar Air flow
b. Lumulous Air Flow
c. Longitudinal Air Flow
d. Laminar Air Filtration

4. Full form of HEPA:

a. High-efficiency particulate air
b. High-efficiency particulate area
c. High-efficiency practice air
d. High-emmergency particulate air

5. Temperature required by autoclave for sterilization:

a. 1310C for 15-25 minutes
b. 1210C for 20-30 minutes
c. 1210C for 15-20 minutes
d. 1300C for 25-35 minutes

6. Temperature required by Hot air oven for sterilization:

a. 1500C for 01 Hr.
b. 1400C for 02 Hr.
c. 1600C for 30 min.
d. 1700C for 01 Hr.

7. The laminar air flow removes particles …… with ….% efficiency.

a. 0.5µ, 99.97%
b. 0.3µ, 99.97%
c. 0.1µ, 96.32%
d. 0.4µ, 90.67%

8. Rubber gloves & Bulk solutions are sterilized by using:

a. Hot air oven
b. Autoclave
c. Incubator
d. LAF
9. Test-tubes, pipettes are sterilized by using:
a. Hot air oven
b. Autoclave
c. Incubator
d. LAF

10. Write full form of SWFI

a. Sterile Water for Inhalation
b. Sterile Water Injection
c. Sterile Water for Ingestion
d. Stable Water Injection

11…….type of glass used for tablets & oral liquids.

a. Type-I
b. Type-II
c. Type-III
d. Type-IV

12. …….Indicator is used for hydrolytic resistance test.

a. Methyl Red
b. Methyl Orange
c. Phenol Red
d. Methyl Blue

13. Type-III type of Glass is composed of:

a. Treated soda lime
b. Borosilicate
c. Soda-lime
d. General Soda-lime

14. Which of the following Full form is correct for SVP:

a. Small Volume Parenterals
b. Single Volume Parenterals
c. Small Volume Products
d. Small Volume Preparations

15. Which of the following Full form is correct for LVP:

a. Large Volume Preparations
b. Large Volume Parenterals
c. Large Volume Products
d. Low Volume Preparations

16. Which of the following test is used for evaluation of Water for Injection
as per I.P.1996:
a. Heavy Metals
b. Fehling’s test
c. Molisch test
d. Benedicts test

17. …….. is the example of polyols.

a. Glycerol
b. Sucrose
c. Dextrose
d. NaCl

18. The containers & closures that are used for packaging of parenteral
products must:
a. Maintain the sterility of packed products
b. Withstand sterilization
c. Be compatible with packed fluids
d. All of the above

19. Large Volume parenterals are packed in:

a. PVC Collapsible bags
b. Glass container
c. Semi-rigid polythene containers
d. All of the above

20. Monesty Electrically Heated Automatic Water Still is also called as:
a. Stokes Still
b. Autoclave
c. Hot Air Oven
d. LAF

21. …. are the products of metabolism of micro-organism.

a. Vaccine
b. Pyrogen
c. Bacteria
d. None of the above

22. …. When entered in human body increases body temperature, chills,

body ache & headache.
a. Micro-organism
b. Bacteria
c. Pyrogen
d. Foreign substance

23. The rabbit which is used for Pyrogen testing having …… weight.
a. 2.5 kg
b. 1.5 kg
c. 1 kg
d. 2 kg

24. Which of the following produces more potent pyrogenic substance as

an endotoxin.
a. Gram negative
b. Gram positive
c. Virus
d. All of the above
25. Which of the following is correct formula for Compound Sodium
Chloride Intravenous Infusion I.P.

a. Sodium Chloride: 0.86 gm

Potassium Chloride: 0.030 gm
Calcium Chloride: 0.030 gm
Water for Injection IP: 100 ml

b. Sodium Chloride: 0.96 gm

Potassium Chloride: 0.030 gm
Calcium Chloride: 0.033 gm
Water for Injection IP: 100 ml

c. Sodium Chloride: 0.86 gm

Potassium Chloride: 0.033 gm
Calcium Chloride: 0.030 gm
Water for Injection IP: 100 ml

d. Sodium Chloride: 0.86 gm

Potassium Chloride: 0.030 gm
Calcium Chloride: 0.033 gm
Water for Injection IP: 100 ml

26. Which of the following is correct category for Compound Sodium

Chloride Intravenous Infusion I.P.
a. Irrigation solution
b. Fluid & electrolyte replenisher
c. Both a & b
d. None of the above

27. The solution which having same osmotic pressure as that of body
fluids is called as:
a. Osmotic solution
b. Isotonic solution
c. Hypertonic solution
d. Hypotonic solution

28. The solution which having high osmotic pressure as that of body
fluids is called as:
a. Osmotic solution
b. Isotonic solution
c. Hypertonic solution
d. Hypotonic solution

29. The solution which having low osmotic pressure as that of body
fluids is called as:
a. Osmotic solution
b. Isotonic solution
c. Hypertonic solution
d. Hypotonic solution

30. When …… is injected in to blood stream water passes outwords

through the cell wall causing shrinkage of cells.
a. Osmotic solution
b. Isotonic solution
c. Hypertonic solution
d. Hypotonic solution

31. When ….. is injected in blood stream, water enters in to RBC’s &
the cells swell rapidly until they burst leading to haemolysis.
a. Osmotic solution
b. Isotonic solution
c. Hypertonic solution
d. Hypotonic solution

32. Which of the following is used as quality control tets for transfusion
fluids?
a. Sterility test
b. Pyrogen test
c. Clarity test
d. All of the above

33. The process of providing aseptic area, i.e. microbes free working
condition during processing, thus it prevents contamination of the
product is known as:
a. Aseptic area
b. Sterilizing area
c. Anti-Microbial area
d. All of the above

34.Which of the following filter is used in laminar air flow bench.

a. Pre-filter
b. HEPA filter
c. Only b
d. Both a & b

35. Flame photometer is capable for estimation of which of the following

ions.
a. Sodium
b. Potassium
c. Calcium
d. All of the above

36. Which of the following type of water is used for drinking purpose?
a. Potable water
b. Sterile water for injection
c. Water for injection
d. Purified water

37. Which of the following type of glass has high hydrolytic resistance
capacity?
a. Type-I
b. Type-II
c. Type-III
d. Type-IV
38. Which of the following formula is correct for 0.9% Sodium Chloride
Intravenous Infusion IP?
a. NaCl: 0.9 gm
Water for Injection: 500 ml

b. NaCl: 0.99 gm
Water for Injection: 100 ml

c. NaCl: 0.9 gm
Water for Injection: 100 ml

d. NaCl: 0.1 gm
Water for Injection: 100 ml