7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch : B

Pharmacology-II (PR) (Subject Code :

BP507P) Batch : B
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Pharmacology-II (PR) (Subject Code : BP507P)

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch : B

5. If a fibrinolytic drug is used for treatment of acute myocardial infarction, the

adverse drug effect that is most likely to occur is .... *

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Acute renal failure

Development of antiplatelet antibodies

Encephalitis secondary to liver dysfunction

Hemorrhagic stroke

Neutropenia

6. If the patient has a history of gout, which of the following drugs is most likely to
exacerbate this condition? *

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Colestipol

Gemfibrozil

Lovastatin

Niacin

Simvastatin

7. In a patient receiving digoxin for congestive heart failure, condition that may
facilitate the appearance of toxicity include .... *

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Hyperkalemia

Hypernatremia

Hypocalcemia

Hypomagnesemia

All of the above

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch : B

8. A drug lacking vasodilator properties that is useful in angina is *

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Isosorbide dinitrate

Metoprolol

NIfedipine

Nitroglycerin

Verapamil

9. Drugs used in asthma that often cause tachycardia and tremor include *

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Beclomethasone

Cromolyn sodium

Ipratropium

Metaproterenol

10. Which of the following cardiovascular agents is classified chemically as a

glycoside? *

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Nifedipine

Digoxin

Flecainide

Cholestyramine

Warfarin

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11. Low concentrations of heparin selectively interfere with the following coagulation
pathway(s) *

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Intrinsic pathway

Extrinsic pathway

Common pathway

No any pathway

12. Low doses of heparin prolong *

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Bleeding time

Activated partial thromboplastin time

Prothrombin time

Blood pressure

13. Which of the following can be used to antagonize the action of heparin in case of
overdose ? *

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Heparin sulfate

Dextran sulfate

Protamine sulfate

Ancrod

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch : B

14. Blood level of which clotting factor declines most rapidly after the initiation of
warfarin therapy *

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Factor VII

Factor IX

Factor X

Prothrombin

15. The following drug reduces the effect of oral anticoagulants *

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Broad spectrum antibiotic

Cimetidine

Aspirin

Oral contraceptive

16. The most definite beneficial results are obtained in the use of anticoagulants for
the following purpose *

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Prevention of recurrences of myocardial infarction

Prevention of venous thrombosis and pulmonary embolism

Cerebrovascular accident

Retinal artery thrombosis

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7/6/2021 Pharmacology-II (PR) (Subject Code : BP507P) Batch : B

17. Anticoagulants are indicated in

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Immobilized elederly patients

Buerger’s disease

Stroke due to cerebral thrombosis

All of these

18. The most important complication of streptokinase therapy is *

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Hypotension

Bleeding

Fever

Anaphylaxis

19. The preferred route of administration of streptokinase in acute myocardial

infarction is *

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Intravenous

Subcutaneous

Intracoronary

Intracardiac

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20. Aspirin prolongs bleeding time by inhibiting the synthesis of *

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Clotting factors in liver

Prostacyclin in vascular endothelium

Cyclic AMP in platelets

Thromboxane A2 in platelets

21. Route of heparin administration is *

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Oral

Subcutaneous

Intramuscular

Sublingua

22. Severe cases of bleeding due to fibrinolytic agents are treated with *

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Aspirin

Heparin

EACA (Epsilon Amino Caproic Acid)

Vitamin K

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23. Hydroxyethyl starch is a *

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Plasma expander

Haemostatic

Heparin substitute

Bile acid sequestrant

24. All of the following are generalmechanisms of drug permeation Except *

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Aqueous diffusion

Aqueous hydrolysis

Lipid diffusion

Pinocytosis or endocytosis

Special carrier transport

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