Professional Documents
Culture Documents
Lecture - 1 (6 Slides Per Page)
Lecture - 1 (6 Slides Per Page)
Lecture - 1 (6 Slides Per Page)
Staff – Coordinators
Dr Enes Makalic
Biostatistics POPH90013
High Dimensional Analytics (Unit Head)
Enes Makalic Room 309, Level 3, 207 Bouverie Street
Centre for Epidemiology and Biostatistics
Melbourne School of Population and Global Health
emakalic@unimelb.edu.au
1 2
Kirkwood BR, Sterne JAC. • If you are only doing Biostatistics and will NOT be enrolling into other statistics subjects
– Stata/IC 16, 6 Month license (~$82)
2nd Edition, 2003
• Biostatistics subjects in the future
Wiley-Blackwell – Stata/IC 16, Perpetual license (~$382)
3 4
Calculators Sessions (1 – 6)
Teaching
• The only University approved calculator is Week
Lecture Chapter Practicals Date
– Casio FX82 (any suffix) 1 Introduction, datasets & types of variables 2 None March 4th
5 6
1
20/02/2020
Teaching
Lecture Chapter Practicals Date
Week Date & Time Due Content
7 Proportions & confidence intervals 15 & 16 Tutorial April 22nd Assignment 1 Monday 20th April, 1pm All material covered in the
30% of the total mark lectures, tutorials and Stata
8 Measures of association 16 & 37 Tutorial April 29th sessions in weeks 1 to 6.
Controlling for confounding: stratification & Tutorial May 6th
9 18, 19 & 20 Monday 18th May, 1pm All material covered in the
regression Stata Practical* Thu/Fri 7th/8th Assignment 2
40% of the total mark lectures, tutorials and Stata
10 Design, sample size & statistical power 35 Tutorial May 13th
sessions in weeks 7 to 10.
Tutorial May 20th
11 Simple linear regression 10
Stata Practical* Thu/Fri 21st/22nd
Examination June All material covered in
12 Revision Tutorial May 27th (2.0 hours, 15 minutes reading time) 30% of the total mark weeks 1 to 11.
Open book, basic calculator required.
7 8
• Students may apply for an extension if… • Students whose studies are genuinely and significantly
– unforeseen circumstances arise that impair a student’s impacted by:
ability to submit an assessment
– Exceptional or extenuating circumstances outside of
their control
• Extension
– Should be submitted before the assignment due date – Events or circumstances of national or state
– Maximum extension is 10 working days significance
• Policy and how to apply: Canvas, Assessment section • Detailed information: Canvas, Assessment section
9 10
• A reduction of 5% for each day the work is late within the first • Submitting the correct assignment is your responsibility
week
• Eight to fourteen days after the due date, 50% will be • Submission of wrong file:
deducted
• Late assignment penalties apply
• After 14 days no mark will be awarded • Or treated as non-submission (0%) if the error is not found
prior to return of the assignments
• If you have applied for an extension or special consideration
these penalties do not apply
11 12
2
20/02/2020
• Information on definitions, advice & penalties • Statistical methods may seem very difficult
– But only from the first look
https://academichonesty.unimelb.edu.au/
13 14
15 16
• Statistics
Avg. Height = 173cm
– Uses the sample to make inferences about the population
INFERENCE
17 18
3
20/02/2020
Statistical Inference – Example 2 (Mobile phones) Data sets, observations and variables
19 20
• To study the effects of vivax malaria infection during pregnancy ID Maternal age Birthweight Vivax malaria
(years) of baby ever during
(gms) pregnancy
1 17 2900 No
2 16 2600 No
3 19 2950 Yes
4 18 3200 No
5 19 2500 No
6 35 2900 No
Source: Nosten F et al. Lancet 1999; 354:546-549
21 22
• Numerical • Continuous
– Continuous – Can take any value
– Discrete – Measured on a continuous scale
– Examples: Height, body weight, blood pressure,
• Categorical haemoglobin level
– Nominal
– Ordinal
23 24
4
20/02/2020
• Discrete • Nominal
– Can only take certain values – No ‘natural’ ordering
– Binary variable – two values only
– Usually whole numbers
– Examples: male or female; alive or dead;
– Examples: Parity, number of visits to hospital, number experimental groups; blood group O, A, B, or AB;
of people in a household place of birth
25 26
27 28
Outcome and exposure variables Why is it important to know the variable type?
• Outcomes are the variables we want to know more about • Absolutely critical to choosing the appropriate form of
statistical analysis
• Exposures are the variables we think might explain the
variation in outcomes • Type of the outcome variable
– Dictates the chosen statistical model
• Statistics quantifies the association between outcomes
and exposures
29 30
5
20/02/2020
Summary
• Population, sample
• Variables
– Numerical
• Continuous, discrete
– Categorical
• Nominal, ordinal
– Derived
31