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Goulds Pathophysiology
For The Health
Professions 6th Edition
Hubert
Test Bank
Chapter01:IntroductiontoPathophysiologyT
estBank

MULTIPLECHOICE

1. Whichofthefollowingwouldbethe mostlikelycauseofaniatrogenicdisease?
a. Aninheriteddisorder
b. Acombinationofspecificetiologicalfactors
c. Anunwantedeffectofaprescribeddrug
d. Prolongedexposuretotoxicchemicalsintheenvironment
ANS:C REF:6

2. Themanifestations ofadiseasearebestdefined asthe:

a. subjectivefeelings ofdiscomfort duringachronicillness.
b. signsandsymptoms ofadisease.
c. factorsthatprecipitateanacute episodeofachronicillness.
d. earlyindicators oftheprodromal stageof infection.
ANS:B REF:6

3. Thebestdefinition ofthetermprognosis isthe:

a. precipitatingfactorscausinganacute episode.
b. numberof remissions tobeexpected duringthecourseofa chronicillness.
c. predictedoutcomeorlikelihood ofrecoveryfrom aspecificdisease.
d. exacerbationsoccurring duringchronicillness.
ANS:C REF:7

4. Whichofthefollowingisconsidered a systemicsignofdisease?
a. Swellingoftheknee
b. Fever
c. Painintheneck
d. Redrashontheface
ANS:B REF:6

5. Etiologyisdefinedas the studyofthe:

a. causesof adisease.

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b. courseof adisease.
c. expectedcomplicationsofadisease.
d. manifestationsofadisease.
ANS:A REF:5

6. Atypeofcellularadaptation inwhich thereis adecreaseincell sizeis referredto as:

a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS:D REF:8

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7. Achangeinatissuemarked by cellsthat varyin sizeand shapeandshow

increasedmitoticfigureswould becalled:
a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS:C REF: 8

8. Adeficitofoxygen inthecellsusually duetorespiratoryorcirculatoryproblemsiscalled:

a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS:B REF:9

9. Whenagroupofcellsin thebody dies,thechangeiscalled:

a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS:D REF:10

10. Rigorousweightlifting/bodybuildingregimensmayresultintheskeletalmusclecells
undergoing:
a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS:A REF: 8

11. Thetermcancer refersto:

a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignantneoplasm.
ANS:D REF: 9

12. Towhich ofthe followingdoes thetermapoptosis refer?

a. Increasedrateofmitosisbycertaincells
b. Ischemicdamagetocells
c. Liquefactionofnecrotictissue
d. Preprogrammedcellself-destruction
ANS:D REF:9

13. Whichofthefollowing statementsis TRUE?

a. AlterationofDNAdoesnotchangecellfunction.

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b. Damagedcellsmaybeabletorepairthemselves.
c. Alltypes ofcells dieat thesame rate.
d. Mildischemiacausesimmediatecelldeath.
ANS:B REF:10

14. Caseationnecrosisrefers toanareawhere:

a. cellproteinshavebeendenatured.
b. cellareliquefiedby enzymes.
c. deadcellsformathickcheesysubstance.
d. bacterialinvasionhasoccurred.
ANS:C REF:10

15. Routineapplicationofsunblockto skinwouldbe anexampleof:

a. aniatrogenic causeofcancer.
b. apreventivemeasure.
c. aprecipitatingfactor.
d. apredisposingcondition.
ANS:B REF:6

16. Acircumstancethat causesasuddenacute episodeofachronicdiseasetooccur istermed:

a. latentstage.
b. predisposingfactor.
c. incidence.
d. precipitatingfactor.
ANS:D REF:7

17. Thetermhomeostasisrefersto:
a. thecausative factorsina particulardisease.
b. maintenanceof astableinternalenvironment.
c. aconditionthattriggersanacuteepisode.
d. acollectionofsignsandsymptoms.
ANS:B REF:2

18. Whichtermis usedto describeanewand secondaryoradditionalproblemthatarises

aftertheoriginaldiseasehas beenestablished?
a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS:D REF:7

19. Pathophysiologyinvolvesthestudyof:
a. the structureof thehuman body.
b. thefunctionsof variousorgansin thebody.
c. functionalorstructuralchangesresultingfromdiseaseprocesses.
d. variouscellstructuresandrelatedfunctions.

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ANS:C REF:2

20. Whichofthe followingis the bestdefinition ofepidemiology?

a. Thescienceof trackingtheoccurrenceanddistribution ofdiseases
b. Therelative numberofdeathsresulting froma particulardisease
c. Identificationofaspecificdiseasethrough evaluation of signsand symptoms
d. Theglobalsearchforemergingdiseases
ANS:A REF:7

21. Whichofthefollowingcancause cellinjury ordeath?

1. Hypoxia
2. Exposuretoexcessive cold
3. Excessivepressureonatissue
4. Chemicaltoxins
a. 1, 2
b. 2, 4
c. 1, 3, 4
d.1, 2, 3, 4
ANS:D REF:9

22. Allof thefollowing arepart ofthe SevenSteps toHealth EXCEPT:

a. followcancerscreening guidelines.
b. usesun blockagents wheneverexposed.
c. participateinstrenuousexerciseon aregulardailybasis.
d. choosehighfiber, lower fatfoods.
ANS:C REF:2

23. Theterm diseaserefers to:

a. theperiod ofrecovery andreturn toa normal healthystate.
b. adeviation fromthenormalstate ofhealth andfunction.
c. thetreatmentmeasuresusedtopromoterecovery.
d. abasiccollection ofsigns andsymptoms.
ANS:B REF:2

24. Acollectionofsignsandsymptoms,oftenaffectingmorethan oneorganor

system,thatusuallyoccurtogether inresponse toa certainconditionis referredtoas a(an):
a. acutedisease.
b. multiorgandisorder.
c. syndrome.
d. manifestation.
ANS:C REF:7

25. Allofthefollowingstatements arecorrect aboutcell damageEXCEPT:

a. Theinitialstageofcelldamageoftencausesanalterationinmetabolic reactions.
b. Ifthe factorcausing the damageis removedquickly, thecell
maybeabletorecoverand return to its normal state.
c. Ifthe noxious factor remainsforan extended period oftime, thedamagebecomes

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irreversible andthecelldies.
d. Initially,celldamagedoesnotchangecellmetabolism,structure,orfunction.
ANS:D REF:9

26. Whichofthefollowing conditionsdistinguishesdouble blindstudiesused inhealthresearch?

a. Neitherthemembers ofthecontrol grouportheexperimental group
northepersonadministeringthetreatment knowswho isreceiving theexperimental
therapy.
b. Bothgroupsofresearch subjectsandtheperson
administeringthetreatmentknowwhois receiving theexperimental therapy.
c. The research subjects do not know, but the person administering the
treatmentknowswho is receiving placebo orstandard therapy.
d. Onlymembers ofthe controlgroup knowthey are receiving standardtherapy.
ANS:A REF:3 |4

27. Ifthedata collectedfromtheresearchprocess

confirmthatthenewtreatmenthasincreasedeffectivenessand is safe,this is called:
a. theplacebo effect.
b. evidence-basedresearch.
c. blindresearchstudies.
d. approval forimmediatedistribution.
ANS:B REF:4

28. Ashort-termillnessthatdevelopsveryquicklywithperhapsahighfeverorseverepainiscalled:
a. acute.
b. latent.
c. chronic.
d. manifestation.
ANS:A REF:6

29. Thetermprognosisreferstothe:
a. periodofrecovery andreturn toa normalstate.
b. expectedoutcomeofthe disease.
c. mortalityand morbidityrates foragivenpopulation.
d. typicalcollectionofsignsandsymptoms.
ANS:B REF:7

30. Whenprolongedischemiaoccurs toanareaofthe heart,theresultingdamageis referredtoas:

a. atrophy.
b. liquefactivenecrosis.
c. apoptosis.
d. infarction.
ANS:D REF:10

31. Duringtheevaluationprocessfor anewtherapy’s

effectivenessandsafety,adoubleblindstudymay beconductedduring:
a. thefirststage.

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b. thesecondstage.
c. thethirdstage.
d. anyofthesestages.
ANS:C REF:3

32. Whyarethepredisposingfactors foraspecificdiseaseimportanttohealthprofessionals?

a. Topredicttheprognosis
b. Todeterminetreatments
c. Todeveloppreventivemeasures
d. Todevelopmorbiditystatistics
ANS:C REF:3

33. Celldamagemaybecaused byexogenoussourcessuchas:

a. abnormalmetabolicprocesses.
b. certainfood additives.
c. geneticdefects.
d. localizedhypoxia.
ANS:B REF:9 |10

34. Whichofthefollowing is usuallyincluded in amedical history?

1. Pastillnessesorsurgeries
2. Currentillnesses,acuteandchronic
3. Prescribedmedicationorothertreatments
4. Nonprescriptiondrugsandherbal remedies
5. Currentallergies
a. 1, 3
b. 2, 4, 5
c. 1, 3, 4
d.1, 2, 3, 4, 5
ANS:D REF:4|5

35. Asituationwhenthereisahigherthan expectednumberofcases of

aninfectiousdiseasewithinagiven areais called a/an:
a. epidemic.
b. exacerbation.
c. morbidity.
d. pandemic.
ANS:A REF:7

36. Thetermpathogenesis refersto:

a. thedevelopmentof adiseaseorsequenceof events relatedto
tissuechangesinvolvedin thediseaseprocess.
b. thedeterminationofthe cause(s)involvedinthe
developmentofamalignantneoplasm.
c. thespecificsigns andsymptoms involvedinthe
changefromanacutediseasetoachronicdisease.
d. thechangesincells ofaffectedtissuethat resultinnecrosis.

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ANS:A REF:6

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