The PFT Lexicon

I promised this a long time ago, and I finally have completed it. What you have here is everything most RTs and respiratory
patients need to know about pulmonary function testing (PFT).

Much of the following information was obtained from the asthma guidelines and "Fundamentals of Respiratory Care" and
reorganized so it's easy for us humble RTs and respiratory patients to understand.

Pulmonary Function Test (PFT): Synonym: Spirometry. This is a test where you breath into a mouthpiece to a device called a
spirometer. The Spirometer measures your lung function, determines if you have lung disease and if you do how severe your lung
disease is.

 It's a test that uses a spirometer that measures airflow, usually before and 15 minutes after using rescue medicine. The
test is not used to diagnose but to determine the type of airway disease a patient has (obstructive or restrictive), the
degree or severity of airflow obstruction, and whether it is reversible over the short term.
 It measures the maximal volume of air forcibly exhaled from the point of maximal inhalation (FVC) and the volume of
air exhaled during the first second of this meneuver (FEV1). It is valuable for children greater than 5 years old (some
children cannot do it until they are 7).
 it can help a doctor determine if shortness-of-breath is due to restrictive diseases like obesity, pregnancy, pneumonia,
cancer, pleural effusion, etc., or an obstructive
disorder like COPD and asthma. Also, it can also be used to differentiate COPD from asthma. Thus, if you are
considering Asthma or COPD, this is a great test to rule out other disease processes.
 A test used most often for assessing the risk of future adverse events in asthma and COPD patients. It is the best test for
determining severity of obstruction.
 Patient's perception of airflow obstruction is highly variable, and spirometry sometimes reveals obstruction much more
severe than would have been estimated from the history and physical examination.
 For diagnostic purposes, spirometry is generally recommended over measurement with a peak flow meter, because
values for each brand of peak flow meter can be specific to that particular brand. (peak flow meters should be used for
patient monitoring only, not diagnosing).
 Followup spirometrymeasures are indicated as asthma control improves.

Spirometry frequency: Spirometry is recommended at the following frequencies: (1) at the time of initial assessment, (2) after
treatment is initiated and symptoms and PEF have stabilized, (3) during periods of progressive or prolonged loss of asthma
control, and (4) at least every 1-2 years.

Abnormalities of lung function: Are considered as restrictive or obstructive defects.

Restrictive Diseases:

 Is indicated by proportianately reduced FVC (or FEV6 in adults) with a normal or increased FEV1/FVC (or
FEV1/FEV6) ratio.
 are caused by anything that decreases the lungs ability to expand and properly ventilate the patient by getting rid of
CO2 from the blood and adding O2 to the blood stream. The following are restrictive diseases:Sarcoidosis, pulmonary,
fibrosis, pneumonia, cancer, granulomatous disorder, obesity, pregnancy, pneumothorax, pleural effusion,
kyphoscoliosis, emphysema (loss of lung tissue), Neuromuscular and neurologic (Guillain-Barre Syndrome, polio
myelitis or myasthenia gravis), Pickwickian syndrome, and Pleurisy.

Obstructive Diseases:

 a) Is indicated by a reduced ratio of FEV!/FVC or FEV1/FEV6

 b) Airway obstruction is anything that causes narrowing or blocking of the Air passages that results in a decreased
exhaled airflow. The causes of airway obstruction are as follows:
 Upper Airway obstruction: Rhinitis/ pharyngitis, Diptheria, Croup,
Epiglottitis, Obstructive Sleep Apnea, Laryngeal paralysis, Tracheal
stenosis, Tracheal malacia, Foreign body, Tetanus
  Lower Airway obstruction: Emhysema, Chronic bronchitis, Asthma, Cystic
fibrosis, bronchiectasis, Bronchiolitis, Bronchial cmpression (tumor, lymph
nodes), Endobronchial tumors, Foreign body, and Mucus plugging.

Significant reversibility: Is indicated by an increase in FEV1 of greater than 200 ml and greater than 12% from the baseline
measure of inhalation of rescue medicine (Albuterol breathing treatment or 2 puffs Albuterol MDI).

Severity of abnormality of spirometric values: is evaluated by comparison of the patient's results with reference values based on
age, height, sex and race.

Impairment: An assessment of the frequency of intensity of symptoms and functional limitations that a patient is
experienciencing or has recently experienced.

Risk: is an estimate of the likelihood of either asthma or COPD exacerbations or of progressive loss of pulmonary function over
time. Some degree of the risk of exacerbations can be obtained from the medical history and patient assessment. Patients who
have had exacerbations requiring ER visits, hospitalization, or ICU admissions, especially in the past year, have a great risk of
exacerbations in the future.

Dyspnea tolerance: The inibility of a patient to notice when he or she is dyspneic (feeling like he or she cannot get air in).
Patients who perceive the degree of airflow poorly. Usually they are hardluck asthmatics who are short of breath so often they
lose the objective means of perceiving degree of dyspnea. Or, patients who have unconsciously accomodated to their symptoms.
Spirometry or peak flow monitoring are useful tools in monitoring asthma for these patients.

Percent predicted: This is a formula for determing the predicted normal for a person based on age, height and weight and body
mass index. You can find a calculator for finding your percent predicted by clicking here.

FVC: The maximum volume (in liters) of air that you can exhale after taking in as deep a breath as you can. FEV1 and FEV6 are
both calculated from the FVC. In severe cases where airway obstruction is present (asthma, COPD) the FVC may be reduced due
to air trapping of air in the lungs.

FEV1:

(1)A measurement made during a spirometry test which measures the amount of exhaled air during the first second of FVC. One
is considered to have "airflow obstruction" when this value is low in comparison to patient predicted. This measurement is
considered the best way of diagnosing obstructive disorders
because it cannot be faked.

(2)The post bronchodilator FEV1 can be used to determine lung growth paterns over time.

(3) A low FEV1 indicates current obstruction and risk for future exacerbation.

(4) A baseline FEV1 (before using bronchodilator) that is lower than normal but that increases by at least 12-15% 15 minutes
after inhaling rescue medicine (Albuterol) is indicitive of airflow obstruction that is reversible. This appears to be a useful
measure indicating risk of exacerbations.

(5) Normal FEV1 is 80% of the predicted value. The predicted value is based on a formula using age, weight and height.

FEV1/FEV6: A measurement made during a spirometry test which measures the amount of exhaled air during the first six second
of the meneuver. This test is used as a substitute for FEV1 in adults who have significant air trapping and who get "light headed"
while trying to forcibly do spirometry.

FEV1/FVC: FEV1 expressed as a percent of the predicted value or as a proportion of the forced vital capacity. This appears to be
a more sensitive measure of severity in the impairment domain, especially in children. It may be more reliable in assessing
asthma severity in children as opposed to FEV1 because it is more sensitive.

FEV0.5: Used instead of FEV1 in children because some asthmatic children have a hard time exhaling for a full second.

FEV 0.75: Used instead of FEV1 in children because some asthmatic children have a hard time exhaling for a full second.
Percent change: This is used to determine how much a patient's lungs improve following a bronchodilator. % change =(post-test
FEV1 - Pretest FEV1/ Pretest FEV1 X 100. An increase in expiratory flow greater than 15% indicates beneficial effects of the
medication.

Peak flow meter: This is a device used to determine "how well your lungs are functioning," according to National Jewish Health.
This is recommended as part of the asthma action plan for children and anyone who has difficulty perceiving asthma symptoms.
It should be noted that peak flows are a great tool for monitoring asthma status, but should not be used to diagnose.

Diffusion capacity: The surface area of the lung where oxygen can 'get in' to the body is very limited in people with COPD. For
example, in patients with emphysema, both the small air sacs (alveoli) and the small blood vessels (capillaries) that run past them
are destroyed, leaving a smaller area for oxygen to come in contact with the oxygen-carrying proteins in the blood (hemoglobin).

"Diffusing capacity" refers to the capacity of the lung to release carbon dioxide and take in fresh oxygen. This lung function test
measures the amount of area of the lung where oxygen can move into the blood vessels. It is performed much like the spirometry
test, except that during this test, you breathe in a small amount of carbon monoxide gas. Carbon monoxide is used because it
binds very quickly and well with hemoglobin and the amount is easily measured.

The test is usually performed during a single breath. To measure the diffusing capacity, you have to have certain minimal lung
volumes and be able to hold your breath for a brief period of time. Also since diffusing capacity varies with the concentration of
hemoglobin in the blood, the values obtained need to be revised if your hemoglobin level is not normal. (Definition by
nbcnewyork.com)

Severity of obstruction: How severe is your asthma? How severe is your COPD? This can be determined by your pre-
bronchodilator percent of predicted FEV1. Degree of severity:

 Normal: FEV1 80% of predicted value or greater

 Mild: FEV1 65-79% of predicted value
 Moderate: FEV1 50-64% of predicted value
 Severe: 35-49% of predicted value
 Very severe: FEV1 below 35% of predicted value

Degree of Reversibility: (as determined by pre and post bronchodilator FEV1):

 Slight: 15-25% change

 Moderate: 25-50% change
 Marked: Greater than 50% change