An Innovative Implant by

P.4-5

P.6-7

P.8

P.9

P.10

P.11

P.12

P.13

P.14-15

P.16-17

P.18-19

P.20-21

MIS Warranty:

MIS exercises great care and effort in maintaining the superior quality of its
products. All MIS products are guaranteed to be free from defects in material
and workmanship. However, should a customer find fault with any MIS product
after using it according to the directions, the defective product will be replaced.
produced, transcribed, stored in an electronic retrieval system, translated into any language or computer language, or
be transmitted in any form whatsoever, without the prior written consent of the publisher.

Warning: Only a licensed dentist should use these products.

Table of contents.

Introduction
Advantages
Implant range
Implants 3.75mm
Implants 4.20mm
Implants 5mm
Implants 6mm
Mountless
Restorative procedure
Success
Analysis reports
Packaging
 4.

At MIS, our scientists and engineers are dedicated to

the development of sophisticated new products and

technologies for the global dental implantation market.

Laboratory and field studies are conducted jointly with

prestigious dental laboratories and university dental

schools. The exhaustive research and development that

went into the SEVEN has created a successful product

whose unique shape gives it many advantages.

© MIS Wszystkie prawa zastrzeżone.

MIS regulatory approvals: MIS

products are cleared for marketing
in the USA .All MIS products and
process comply with ■ ISO 9001:
2000 - quality management
system ■ ISO 13485:2003 quality
management system for medical
devices ■ 93/42/EEC - EC directive
for medical devices.
5.
6.

Screw type implant standard

platform Ø 4.20mm.
new surface morphology

Advantages.
Successful
High success rate, provided by a combination of advanced
geometric design and new surface morphology.

Forgiving
SEVEN is designed for implantation in a wide range of bone
types and bone augmentation procedures.

Simple
A specially designed final drill is supplied with every implant,
allowing a short and safe drilling procedure.

Easy
Increased insertion speed is provided by a dual thread
of 2.4mm, combined with self-drilling capability.

Initial Stability
The thread thickness changes from the apex to the neck with the
same pitch, improving the compression of the bone during insertion.
Micro Rings on the implant neck provide better initial stability by
improving the interfacial shear strength at the crestal zone.

Minimal Bone Resorption

The surface roughness over the entire body, together with the high level
of surface morphology, prevents bone resorption at the implant’s neck.

Self-Tapping
SEVEN cuts its own threads during implantation, minimizing friction-generated
heat. Three spiral channels running the length of the fixture fill with bone chips
during implantation to improve integration.
 8.

Screw type
implant range
Standard and wide platform.

Standard

Length 8mm 10mm 11.50mm 13mm 16mm Implants cover

screws and
Type MF7-08375 MF7-10375 MF7-11375 MF7-13375 MF7-16375 healing caps.
Available in gingival
heights: 3,4,5,6mm
Ø 3.75mm
Screw type
implant standard
platform MC1-00375

 Ø 4mm

MF7-08420 MF7-10420 MF7-11420 MF7-13420 MF7-16420 3/4/5/6mm

MH-03375
MH-04375
MH-05375
MH-06375
Ø 4.20mm
Screw type  Ø 5.5mm
implant standard
platform 3/4/5/6mm
MH-53375
MH-54375
MH-55375
MH-56375

Wide

Implants cover
MF7-08500 MF7-10500 MF7-11500 MF7-13500 MF7-16500 screws and
healing caps.
Ø 5mm Available in gingival
heights: 3,4,5,6mm
Screw type
implant wide
platform
MC1-00470

MF7-08600 MF7-10600 MF7-11600 MF7-13600  Ø 5mm

3/4/5mm MH-W3500
MH-W4500
Ø 6mm MH-W5500

Screw type
implant wide
platform Ø 6.3mm

3/4/5mm MH-W3630
MH-W4630
MH-W5630
 9.

Seven screw type implants

Ø 3.75mm standard platform.

Catalog No. Dimensions Material Description

MF7-08375 Ø 3.75mm Titanium Screw type implant

length 8mm Grade 5 internal hex.
Sand Blasted
Acid-Etched

MF7-10375 Ø 3.75mm 2.45

length 10mm

Ø 3.60 Ø 3.75
MF7-11375 Ø 3.75mm
length 11.50mm

MF7-13375 Ø 3.75mm
length 13mm Ø 2.80 Ø 3.10

Final Drill
A specially designed final drill for
8mm, 10mm, 11.50mm, 13mm and
MF7-16375 Ø 3.75mm 16mm implants is supplied with every
length 16mm implant, allowing a short and safe
drilling procedure.

* all implants include the relevant fixture, cover screw and final drill

Ø 3.75mm Implant Procedure

It is recommended to use the final drill in bone types 1 and 2

1200- 900- 500- 400- 200-

Drill Speed (RPM) 1500 1200 700 700 500 15-25
Diameter  1.90  2  2.80  2.80  3.75  3.75
 3.60
OR

Final drill Countersink

MT-GDN33

Procedure recommended by MIS For bone For bone

cannot replace the judgment and the type 1&2 type 3&4
experience of the surgeon
 10.

Seven screw type implants

Ø 4.20mm standard platform.

Catalog No. Dimensions Material Description

MF7-08420 Ø 4.20mm Titanium Screw type implant

length 8mm Grade 5 internal hex.
Sand Blasted
Acid-Etched

2.45
MF7-10420 Ø 4.20mm
length 10mm

Ø4.10

Ø 3.75
0.4mm
MF7-11420 Ø 4.20mm Ø 4.20
length 11.50mm

MF7-13420 Ø 4.20mm
length 13mm Ø3.30 Ø 3.70

Final Drill
A specially designed final drill for
8mm, 10mm, 11.50mm, 13mm and
MF7-16420 Ø 4.20mm 16mm implants is supplied with every
length 16mm implant, allowing a short and safe
drilling procedure.

* all implants include the relevant fixture, cover screw and final drill

Ø 4.20mm Implant Procedure

It is recommended to use the final drill in bone types 1 and 2

1200- 900- 500- 400- 200- 200-

Drill Speed (RPM) 1500 1200 700 700 400 500 15-20
Diameter 1.90 2 2.80 3.20 3.30  4.20 4.20
4.10

OR

Final drill Countersink

MT-GDN33

Procedure recommended by MIS For bone For bone

cannot replace the judgment and the type 1&2 type 3&4
experience of the surgeon
 11.

21.

Seven screw type implants

Ø 5mm wide platform.

Catalog No. Dimensions Material Description

MF4-08500 Ø 5mm Titanium Screw type implant

length 8mm Grade 5 internal hex.
Sand Blasted
Acid-Etched

2.45
MF4-10500 Ø 5mm
length 10mm
Ø 4.90

Ø 4.50
0.4mm
MF7-11500 Ø 5mm Ø 5
length 11.50mm

MF7-13500 Ø 5mm
length 13mm Ø 4.10 Ø 4.50

Final Drill
A specially designed final drill for
8mm, 10mm, 11.50mm, 13mm and
MF7-16500 Ø 5mm 16mm implants is supplied with every
length 16mm implant, allowing a short and safe
drilling procedure.

* all implants include the relevant, cover screw and final drill

Ø 5mm Implant Procedure

It is recommended to use the final drill in bone types 1 and 2

1200- 900- 500- 400- 400- 200- 200-

Drill Speed (RPM) 1500 1200 700 700 600 400 500 15-20
Diameter  1.90  2  2.80  3.20  3.80  4.10  5  5
 4.90

Final drill Countersink

MT-GDN50

Procedure recommended by MIS For bone For bone

cannot replace the judgment and the type 1&2 type 3&4
experience of the surgeon
 12.

Seven
14. screw type implants
Ø 6mm wide platform.

Catalog No. Dimensions Material Description

MF7-08600 Ø 6mm Titanium Screw type implant

length 8mm Grade 5 internal hex.
Sand Blasted
Acid-Etched

2.45
MF7-10600 Ø 6mm
length 10mm

Ø 5.90

Ø 4.50
0.4mm
MF7-11600 Ø 6mm
length 11.50mm Ø 6

MF7-13600 Ø 6mm
length 13mm
Ø 5.10 Ø 5.50

Final Drill
A specially designed final drill for 8mm,
10mm, 11.50mm and 13mm implants is
supplied with every implant, allowing a
short and safe drilling procedure.

* all implants include the relevant fixture, cover screw and final drill

Ø 6mm Implant Procedure

It is recommended to use the final drill in bone types 1 and 2

1200- 900- 500- 400- 400- 400- 300- 300- 300-

Drill Speed (RPM) 1500 1200 700 700 600 600 500 500 500 15-20
Diameter  1.90  2  2.80  3.20  3.80  4.50  5  5  5.10  6  6
 5.90

OR

Final drill Countersink

MT-GDN50

Procedure recommended by MIS For bone For bone

cannot replace the judgment and the type 1&2 type 3&4
experience of the surgeon
 13.

Mountless.

All MIS BIOCOM and SEVEN implants will now be

supplied without mounts. These successful implants
remain unchanged, but will be supplied without the blue
mounts, and will be packaged in distinctive and easily
recognizable boxes (Page 24). The BIOCOM and SEVEN
mountless implants, have their own tools, available as a
set (MK-0037) or purchased separately.

MountLess Tube.
14. Restorative Procedure
INTERNAL HEXAGON.

Cover Screw Healing Caps Multi units/Ball attachments Impression Coping Analogs Temporary
Cylinders

MC1-00375 MH-03375 MD-I0375 MD-G0213 MD-RSM10 MD-TPH50

MH-04375
MH-05375
MH-06375

Ø3.75
MH-53375 MD-IC200 MD-S0220 MD-TCH13
MF7-08500 MH-54375
MF7-10500 MH-55375
MF7-11500 MH-56375
MF7-13500
MF7-16500

MM-MTP53
Standard Platform

MD-PF375

MB-N1375 MB-RS375
MB-N2375
Ø4.20 MB-N3375
MB-N4375
MF7-08420 MB-N5375
MF7-10420
MF7-11420
MF7-13420 Śruba MM-CT480 MA-RSM10
MF7-16420 zabliźniająca

MA-S1375 MH-00450
MA-S2375 MM-MTP53
MA-S3375
MA-S4375

MC1-00375 MH-W3500 MW-I0375 MD-G0213 MW-RSM10 MW-TPH50

MH-W4500
MH-W5500

MW-IC200
Ø5 MH-W3630
MH-W4630
MF7-08500 MH-W5630
MF7-10500
MF7-11500
MF7-13500 MM-MTP53 MD-S0220
MF7-16500
Wide Platform

MW-PF550

MW-B1500 MB-RS375
MW-B3500
MW-B5500
Ø6
MF7-08600
MF7-10600 Śruba MM-CT480 MA-RSM10
MF7-11600 zabliźniająca
MF7-13600
MA-W1500 MH-00450
MA-W2500
MA-W3500 MM-MTP53
MA-W4500
 Optional screws:

MD-S0200
MD-S0220
MD-G0220
MD-S0222
MD-S0224

Prosthetic Options

ry Plastic Cylinders Gold-Plastic Cylinders Prosthetic Abutments Angulated Abutments

PH50 MD-CP013 MD-GPO10 MD-A0010 MD-P0030 MD-CR010 MD-AN151 MD-P2530

MD-CTP10 MD-MAC10 MD-WMAC1 MD-AN251 MD-P1530

CH13 MD-CPH13 MD-GPC10

MD-CPS01 MM-APC49 MM-CPC49 MD-A1510 MD-A2510

MD-CPS02
MD-CPS03
MD-CPS04

MD-TAD10 ED-CPH80 ED-CP080

MD-TAD20
MD-TAD30
MD-TAD40

MB-SF200 MB-GPS10 MB-TTP10 MB-DMH10

MM-CP045 MM-S0330 MB-MG450 MM-G0330

MM-BGC45

PH50 MW-CP013 MW-GPC10 MW-CTP10 MW-CPS01 MW-TAD10 MW-AN151

MW-CPS02 MW-TAD20
MW-CPS03 MW-TAD30
MW-CPS04 MW-TAD40

MW-CPH13 MW-MAC10 MW-APC49 EW-CPH80 MW-P00N10

MW-CPC49 EW-CP080 MW-P1510

MB-SF200 MB-GPS10 MB-TTP10 MB-DMH10

MM-CP045 MM-S0330 MM-MG450 MM-G0330

MM-BGC45
 16.

Success.

High success rate, provided

by a combination of advanced
geometric design and new
surface morphology.

Micro Structure - Surface Morphology

The surface roughness and microgeometry - High-level of surface morphology.

of titanium is achieved by blasting particles - Increased bone attachment has been
and acid-etching. A larger surface area shown to be optimal with micro-pits
increases bone-to-implant contact, in the 5-10 micron range.
resulting in more area for bone cell
attachment. The micro mechanical fixation
increases the stability of the implants.
 Adsorption of Serum Protein to Modified
Titanium Surfaces
M.N. Sela, L.Badihi, G.Rosen, D.Kohavi and D. Steinberg

The use of Titanium (Ti) implants is a novel clinical procedure in

dentistry. The adsorption of biological molecules to the implant’s
surface triggers a sequence of events that may determine
the outcome of this procedure. Clinical data suggests that
modified Ti surfaces play an important role in the success
or failure of the implant. Objective: the purpose of this study
was to investigate the interaction between Ti implants with
different surface properties and serum proteins, in order to
find the optimal implant surfaces which may improve the
Osseointegration process and implant intake.

Materials & Methods: Six mm in diameter Ti disks with two

types of surface modifications were compared: Machined
and Sandblast plus Acid-Etched. The disks were coated
with mixtures of Human Serum Albumin conjugated with
fluorescein (HAS-FITC).
Following incubation, the coat was removed from the
disks by SDS. A Confocal Scanning Laser Microscope was
used to visualize and measure the HAS-FITC coat and the
degree of protein removal from the Ti surfaces.
Results: The Confocal Microscope images revealed a
significantly higher amount of HAS-FITC coat on the rough
Albumin disks, as compared with the machined disks. Furthermore,
IGG under similar experimental conditions, less HAS-FITC could
Fibronectin
be removed from the rough disks than from the machined
Fibrinogen
disks.
Conclusions: Absorption of albumin to the rough treated
Ti surface is both qualitatively and quantitatively far more
intense, as compared with the machined surfaces. Further
studies of the chemical and physical characterization of the
Mi
modified Ti surfaces are underway. Moreover, additional serum
20
cro proteins, as well as oral microorganisms, are being examined
gra
m for their interactions with the modified Ti surfaces.
15

10

Hebrew University
Jerusalem, Israel, IADR
5 August 03, 2004

Ma
ch
ine

17.
Im SE
VE
pla N
nt
 Micro Structure Micro rings (0.1x0.3) on the
Micro Rings neck provide a better initial
stability by improving the
interfacial shear strength
in the crestal zone.
18.

Surface.
The surface roughness over the entire body, together
with the high level of surface morphology, prevents
bone resorption at the implants’ neck.

Roughness Measurement
The arithmetic average of the deviation Ra is the most commonly used
measurement for surface roughness. The micro geometry of MIS implants
meet the roughness recommended in the international literature.

Instrument:
Parthometer M1
(MAHR)

Ra 2.25micron
Rz 14.65micron
Rmax 15.5micron
R profile 0.25mm
Lt 5.60mm
Lc 0.80mm
Pc (0.5-0.5) 165/c
 19.

Analysis Reports
XPS analysis conditions

Instrument: VG Scientific Sigma Probe

X-Ray Source: Monochromatic Al Kα, 1486.6eV
X-Ray Beam Size: 400 µm

For surface analysis, the samples were irradiated with monochromatic X-rays. Survey spectra were
recorded with a pass energy of 100e V, through which the surface chemical composition was deter-
mined. The atomic concentrations were calculated using elemental sensitivity factors without applying
any standardization procedure. The core level binding energies of the different peaks were normalized
by setting the binding energy for the Cls at 284.5 eV.

For each of the screws, one flat edge area, marked as #1, was analyzed in the as-received state only:

Table 1
XPS Atomic Concentrations (%) for LOT 83

Implants C Ti O N Ca Si S Cl Na Al Cu Mg P V
MF7-13420, thread area 1 25.54 18.19 51.42 0.37 0.92 0.1 - - - 2.91 - 0.27 - 0.28
MF7-13420, thread area 2 28.71 15.99 49.16 0.39 1.00 - - - 0.3 4.04 - - - 0.41
MF7-13375, thread area 1 24.31 19.45 52.71 - - - - 0.12 - 3.08 - - - 0.33
MF7-13375, thread area 2 27.78 16.11 51.31 0.21 0.05 - - 0.78 3.60 - - - 0.16

Table 2
Ti Oxide Thickness (nm) for LOT 83

Samples Oxide Thickness (nm)

MF7-13420, LOT 83 6.5
MF7-13375, LOT 83 6.5

Interpretation of Results:
No strange elements or traces thereof were identified. This means that the surface treatment
(etching) did not leave undesired effects. The C/Ti ratio classified the implants as “normal”. The
ratio admitted is where Ti is 15% and C is 30%.

Solid State Institute

Technion Israel Institute of Technology
Haifa 32000, Israel
 20.

Packaging.
The packaging is designed for ease of use
by the dentist and the distributor.

Implant identification markings

Quick identification of implant size and length.
Upper number represents the implant diameter,
while the lower represents implant length.

Easy pulling tab

The pull tab is easily indentified which
facilitates quick and easy opening.

For the dentist’s use

The implant packaging allows a convenient,
logical arrangement in the drawer and
immediate identification of the parts.
 Implant identification markings
The cap of the outer tube is color-coded
according to the implant diameter.

White
6

New designed molten polystyrene

tubes provide easy use for maximum
convenience. The sterilized tubes are
manufactured in a clean room.

Cover screw

Implant

The packaging is boxed to contain exactly

ten pieces of each item with the same lot
number. It can be used as a stand or in the
drawer, where items can be easily displayed
and readily identified.
All rights reserved. No part of this publication
may be reproduced, transcribed, stored in
an electronic retrieval system, translated into
any language or computer language, or be
transmitted in any form whatsoever, without
the prior written consent of the publisher.
 MC-UNO08 Rev.1
MC-SEVEN Rev.7
0483 ISO 9001:2000
ISO 13485:2003
MIS Implants Technologies Ltd
www.mis-implants.com
MIS Implants Technologies Ltd
0483 ISO 9001:2000
Authorized European Representative:
ISO 13485:2003
M I S I mp l ant s Te c hn o l o gi e s G mb H
P aul i ne n s t r. 12 a , 32427 M ind e n , G E R M A N Y
www.mis-implants.com Tel: +49 571 97 27 69 0 ; Email: service@mis-implants.de
Authorized European Representative:
MIS Germany, Paulinenstraße 12a, 32427 Minden, GERMANY

© MIS Corporation. All Rights Reserved.

© MIS Corporation. All Rights Reserved.