Analytical Chemistry in the Regulatory Science of Medical Devices

Because the need to measure things is fundamental to the regulatory science of

medical devices, analytical chemistry plays an important role, contributing to
medical device technology in two ways: It can be an integral part of an innovative
medical device (e.g., diagnostic devices), and it can be used to support medical
device development throughout the TPLC. In this review, we focus on analytical
chemistry as a tool for the regulatory science of medical devices. We highlight
recent progress in companion diagnostics, medical devices on chips for preclinical
testing, mass spectrometry for postmarket monitoring, and
detection/characterization of bacterial biofilm to prevent infections.

Souce: https://pubmed.ncbi.nlm.nih.gov/29579404/

Role of Analytical Chemistry in Medicine

Analytical chemistry deals with chemical substances. The safety of the food we
eat and the water we drink, in addition to the effectiveness of the
pharmaceuticals we use to cure illnesses, can all be attributed to research and
discoveries by analytical chemists. By definition, analytical chemistry is the
science of obtaining, processing, and communicating information about the
structure of matter. Realistically, the world would be a very different place
without this scientific discipline.
In the field of medicine, analytical chemists help physicians diagnose diseases
through clinical chemistry — analyzing blood gases, enzymes, bacteria, and
other medical samples. Through pathology, analytical chemistry helps us
understand disease through its molecular makeup. The use of instrumentation,
statistics, chemistry, and computers makes analytical chemists essential to
medical research and pharmaceutical development. And, without analytical
chemistry, there would be no forensic science, the sciences used for the
purposes of law.
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Source:https://medium.com/@aveciapharma/role-of-analytical-chemistry-in-
medicine-b3a0870dee0a

Importance of chemistry in the field of medical technology

In chemistry, a medical technologist measures many different proteins and
electrolytes, as well as drug levels used to monitor patient therapy. A medical
technologist working in the chemistry department will tell the doctor many
things. For example, how much sugar is in the patient’s blood, how much protein
is in the patient’s urine, or whether or not the patient has a tumor. Much of the
testing in chemistry is done on automated analyzers. Chemistry is possibly the
largest and most rapidly changing area of the laboratory because of the variety
of automation available. Methods used in chemistry include things like
electrophoresis, spectrophotometry, nephelometry, immunoassays and
electrochemistry. Sound complicated? It’s a mouthful, but that’s why medical
technologists have to be educated!
Source:https://uwosh.edu/medicaltechnology/students/medical-
technologists/#:~:text=urinalysis%20and%20microbiology.-,Chemistry,used%20to
%20monitor%20patient%20therapy.&text=Chemistry%20is%20possibly%20the
%20largest,the%20variety%20of%20automation%20available.

Clinical Chemistry Tests

Clinical chemistry refers to the biochemical analysis of body fluids. It uses
chemical reactions to determine the levels of various chemical compounds in
bodily fluids. Several simple chemical tests are used to detect and quantify
different compounds in blood and urine, the most commonly tested specimens in
clinical chemistry.
Techniques such as spectrophotometry, immunoassays, and electrophoresis are
also used in clinical chemistry to measure the concentration of substances such as
glucose, lipids, enzymes, electrolytes, hormones, proteins, and other metabolic
products present in human blood and urine.
Source:https://www.news-medical.net/life-sciences/Clinical-Chemistry-Tests.aspx