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VENTILATION

SERVO-i FOR NEONATES


SYNCHRONY FOR THOSE
WHO NEED IT MOST
| 2 | SERVO-i for neonates | Critical Care |
| Critical Care | SERVO-i for neonates | 3 |

SERVO-i FOR NEONATES


IMPROVING CARE FOR OUR MOST VULNERABLE

Respiratory support delivered asynchronous to the That is why the electrical activity of the diaphragm (Edi)
baby’s effort has been shown to increase the length of should be regarded as a vital sign for mechanical
stay in the ICU and to prolong mechanical ventilation. ventilation. Edi provides information on patient effort,
Although fundamental to the baby’s comfort and outcome, degree of assist provided by the ventilator and
the problem of asynchrony usually goes undetected and synchrony between the patient effort and the ventilator
untreated. The opportunity to measure and display assist 1. Neurally Adjusted Ventilatory Assist (NAVA) offers
the electrical activity of the diaphragm (Edi) presents a an extension of the baby’s respiratory vital sign as NAVA
totally new insight into how the baby’s respiratory uses the baby’s own biological signal for the generation of
regulation is affected by the disease, and how the baby is ventilatory assist in proportion to the baby’s own effort.
able to cope with the disease process from a respiratory The assistance provided is in synchrony with the baby, is
perspective. insensitive to leaks and will unload the patient work effec-
tively during both invasive and non-invasive
ventilation.

The efficacy of the main respiratory muscles and the pling) is highly efficient (1). Conversely, a higher deflec-
degree of respiratory demand determine the degree of tion of the Edi signal indicates illness or disease (2). For
respiratory center output. In a healthy baby, the low a seriously ill baby with high deflection of the Edi signal,
amplitude of diaphragm excitation (Edi) reflects the fact tidal volume VT may even decrease due to the bio-feed-
that the main respiratory muscle (neuroventilatory cou- back protection mechanisms (3) 2.

Health Disease

V V V V V V V V V
1 2 3

Edi Edi Edi


ml ml ml ml ml ml ml ml ml

VT VT VT
| 4 | SERVO-i for neonates | Critical Care |

The paradigm shift in mechanical ventilation offered by Asynchrony


NAVA is never so obvious as in small children and neo-
nates. Patient-ventilator synchrony used to be difficult to
obtain, unless the patient was heavily sedated or by
administration of neuro muscular blockers, implying that
synchrony could only be achieved if the baby was inactive.

Today, more than 25,000 patients have experienced the


comfort and safety of NAVA. The experience shows that Asynchrony Synchrony
patients are more comfortable and able to control their
own respiration unless there is a direct impairment of the
respiratory centers. Clinical studies are confirming the
benefits to patients by the improved synchrony of NAVA 3.

Asynchrony during conventional NIV Pressure Control ventilation can be


displayed by the superimposed grey curved Edi signal above the pressure
curve. Note the high Edi and FiO 2. Note the asynchrony in both time and
assist.

Synchrony

Asynchrony Synchrony

NIV NAVA in the same patient. Note the unloading effect by the decrease in
Edi, pressure and FiO 2. Note the synchrony in time and assist.
| Critical Care | SERVO-i for neonates | 5 |

SERVO-i FOR NEONATES


VENTILATING WHAT ISN’T THERE

Respiratory failure in newborns and premature babies Fetal lung development


is a reflection of the lack of preparation for the new environ-
Birth
ment. They lack alveoli, surfactant and a functioning chest
wall. In addition, central respiratory regulation is not fully
developed. Each of these issues creates its own problems.
The surface area for gas exchange is limited due to fewer
and immature alveoli. Airways tend to collapse due to surf-
actant deficiency. The lung itself tends to further collapse
under its own weight due to the lack of a functioning chest
wall. In reality, the baby will struggle during inspiration to
Respiratory Alveolar
fill the stiff, collapsed lung and fight during expiration to Alveolar ducts
bronchioles sacs
prevent the lungs from closing, further decreasing the gas
exchange area. The immature respiratory centre causes
16 18 20 22 24 26 28 30 32 34 36 38 Week
central apneas, and if not managed, may lead to impaired
oxygenation.
NAVA works in synchrony with the biological feedback system in premature
babies from week 22-24 4 .
The baby is never allowed to rest!
Obviously, post-natal development will be impaired if all
energy is consumed by the act of breathing. For the baby to
thrive, the energy balance must be shifted.

If the respiratory muscles are weak or the respiratory load


is too high for the premature baby to cope, the work must
be distributed to or taken over by a mechanical ventilator.
Logic states that to maintain and improve the function of
the respiratory muscles, the load should be reduced to
normal while the ventilator accepts the work induced by
disease.

PRIMARY PROBLEMS IN NEONATAL VENTILATION

• Cardiopulmonary systems are not fully developed

• Chest wall is highly compliant with very stiff lungs

• The respiratory centers are immature


| 6 | SERVO-i for neonates | Critical Care |

SERVO-i FOR NEONATES


SYNCHRONY REDEFINED

The breathing pattern of a newborn is highly irregular, Asynchrony due to missed effort
with periods of apneas, sighs and rapid shallow breathing.
Missed effort Missed effort
This is a direct contradiction to the design of mechanical Assist
ventilators that function by the delivery of fixed tidal Pressure

volumes, pressures and respiratory rates. The collision is


unavoidable. The ventilator will deliver set volumes and
pressures in direct conflict with the baby’s respiratory cen-
Respiratory
ter output, both in terms of timing and size, leading to
drive
unnecessary high pressures with a distribution of high
stress tension directly to the limited amount of healthy
Edi signal
alveoli. The conflict is observed as failing gas exchange
and severe respiratory asynchrony.
Traditional ventilators rely on pneumatic sensors to trigger. This creates
inaccuracies between the request and the delivered assist, which can add
With the information provided by standard ventilation up to missed efforts between the baby and the ventilator.
technology, it is difficult to determine if the ventilator
is synchronized to the patient effort.
Asynchrony due to gas delivery in time and assist

Requested
{ Assist
asynchrony
Delay Delay
Delivered
Assist
Pressure

Respiratory
drive

Edi signal

The asynchrony due to delayed trigger of the breath seen in pneumatic


triggered ventilation is eliminated by neural triggering. The asynchrony
between requested and delivered assist can be eliminated by NAVA con-
trolling the assist.

NAVA – synchrony both in time and assist

Time synchrony Assist synchrony

Assist
Pressure

Respiratory
drive

Edi signal

NAVA provides synchrony in both time and assist, reducing WoB and energy
consumption. Provided by the proportional delivery of assist determined by
the babies efforts breath by breath.
| Critical Care | SERVO-i for neonates | 7 |

In fact, ventilator autocycling is often mistakenly inter-


preted as a fast trigger response (see fig). In contrast, the
display of the Edi curve will give you an objective and
immediately accessible tool to monitor the activity of the
patient and the response of the ventilator.

Circuit leak resulting in autocycling. No patient activity seen in the Edi


tracing, resulting in passive filling of the lung.

NAVA WILL REDEFINE SYNHCRONY BREATH BY BREATH

• Decreases airway pressure by bio-feedback 3

• Allows the baby to rest and save energy for growing

• Improves oxygenation and CO 2 washout 4


| 8 | SERVO-i for neonates | Critical Care |

SERVO-i FOR NEONATES


EDI — THE RESPIRATORY VITAL SIGN

Patient-ventilator asynchrony is unavoidable in small The SERVO-i allows you to display the current output
babies with current standard ventilator technology. However, of the respiratory centers to aid in determining how the
assessing if and when to correct the situation is almost patient is coping with their respiratory load. The clinician
impossible, due to the high number of variables. The elec- can now monitor and set the ventilator to allow unloading
trical activity of the diaphragm (Edi) is the compound repre- of the respiratory work induced by the disease, with the
sentative of the respiratory centers. The reaction to patient- patient assuming the fractional work representative of
ventilator asynchrony can sometimes be dramatic and is health 6.
fully visible by the amplitude and tonic activity replicated
by the Edi signal 5 (see fig).

Neonates do not have a stiff chest wall to protect the


patency of the lung. The preterm conserves (FRC) lung
Unloading with NAVA using the Edi signal
Unloading with NAVA using the Edi signal
volume through changes in RR and tonic activity of laryn-
geal and diaphragm muscles. This will often be reflected by
1 2 3
a deviation of the baseline for the Edi, representing tonic Patient Clinicians Increase NAVA-
activity of the diaphragm. This may sometimes be periodic, status decision level to give

but in some instances stationary. This is a potent sign of


serious collapse of the lungs during expiration. A stepwise Edi 20 µV Unload 50 % Edi 10µV
increase in PEEP will usually improve the situation for the
baby, sparing the work of the loss of lung volume during The Edi signal reflects the muscle strength of the diaphragm, the neuro-
expiration (see fig). ventilatory coupling. By reading the Edi signal and observing the patient, a
decision on the level of unloading can be made and subsequently managed
by adjusting the NAVA level.

Baby in severe distress. Note tonic activity and high Edi peak.
Note response and synchronous unloading. The same baby after 4 hours. Note reduction in FiO 2, RR and Edi.

Tonic activity
| Critical Care | SERVO-i for neonates | 9 |

As the respiratory muscles improve and the disease Selfweaning in NAVA


subsides, the patient will essentially wean himself. This can
Edi signal (µV) Tidal volume (ml)
be observed by the decrease in amplitude of the Edi signal
20
and a maintained tidal volume. Weaning thus can be
observed from the Edi, which replicates the improvement in 15 10
respiratory muscle function and biological feedback control.
10
Extubation

0 0
Time

The Edi signal acts as a clear guide in managing weaning or selfweaning.


It is possible to follow the patient’s progress and see when assist is no
longer necessary.

The origin of Edi. The Edi catheter, a nasogastric ventilator to assist the patient (5), which interprets and
feeding tube with electrodes positioned at the level of responds near-instantly with the proportional level of
the diaphragm, captures the electrical activity (1). The support for that breath (6) 7.
raw signals detected by the electrodes during one single
inspiration (2). Filtered signals without the ECG signal
(3). The signals closest to the diaphragm are selected
for the strongest Edi (4). The final Edi signal used by the

2 8
7
Raw signal

6 1
5
4

2
1
6
5
signal
Edi

3 8
7
4
Disturbance

6
filtered

Diaphragm

5
signal

4
3

2
1
| 10 | SERVO-i for neonates | Critical Care |

SERVO-i FOR NEONATES


NON-INVASIVE VENTILATION IN A NEW WAY

Breathing is a well coordinated activity, which requires Epiglottis. Traditional non-invasive ventilators or CPAP
very little effort in health. devices disrupt the natural synchrony between the epiglottis
and diaphragm, making it difficult to swallow or eat. The
The diaphragm, laryngeal and chest wall muscles work in neural triggering of NIV NAVA allows neonate patients to eat
concert to augment the function of every component, there- and swallow comfortably and safely. Breathing mechanism
by protecting the fragile tissues in the lung from the damage opens the epiglottis during inspiration synchronized with the
of a hostile environment. diaphragm. Observations indicate that the lower esophageal
sphinter muscle closes during inspiration preventing air
Incorporating SERVO-i with NAVA into the same bio- leakage to the stomach, when synchronised with the
logical feedback loop as the one controlling the respiratory diaphragm.
muscles means that coordination is fully controlled by the
patient. The biological feedback is suddenly available to
the clinician, whose primary task becomes to assess the
distribution of respiratory work between the patient and the
ventilator. Any change in this balance will be obvious as it
will affect the feedback from the brain and thus the strength
of the Edi signal8.

The natural respiratory biological feedback loop The coordination between airway opening and
in synchrony with the artificial muscle of the diaphragm electrical activity (Edi). Note how the
ventilator controlled by the Edi signal originating airway is fully dilated only at the beginning of the
from the respiratory center. inspiration (1). The airway is then closing to avoid
over-distension of the lung (2, 3) The airway opening
is not fully dilated during expiration to protect the
end expiratory volume (4, 5).

3
4

2
Laryngeal

5
Chest wall
1

Diaphragm
Edi

Ventilator
Artificial muscle
| Critical Care | SERVO-i for neonates | 11 |
| 12 | SERVO-i for neonates | Critical Care |

SERVO-i FOR NEONATES


SHOULD THE PATIENT BE ALLOWED TO CONTROL VENTILATION?

Intubation is the most significant event related to the The immaturity of the respiratory center is managed
development of bronchopulmonary dysplasia (BPD). Data by the back-up system of the SERVO-i, which will react
support efforts to avoid intubation and mechanical ventila- immediately to apnea by providing controlled breaths, and
tion9. There is a broad consensus that CPAP should be the promptly return to NAVA when triggered by patient efforts.
first line of treatment. However, failure of CPAP is common, The decrease in Edi amplitude with maintained tidal
leaving only the option to resort to some form of mechanical volume will show improved efficacy of the respiratory
ventilation. muscles. Decrease in FiO2 needs will show improved gas
exchange.
SERVO-i with non-invasive NAVA opens a totally new
spectrum of opportunities. Non-invasive NAVA can be
administered with any patient interface best adapted to
the patient. The sensing of the patient effort is no longer
a problem, and inspiratory assist will be synchronized to
the patient effort independently of the size of the leak.
Intubation can, in most cases, be reserved for situations
where there is an urgent need to protect the patient airway
or for copious secretion.

WHY THE PATIENT SHOULD CONTROL THE VENTILATOR

• The patient will only receive the assist required, with


the aim of achieving homeostasis.

Leakage independent Automatic back-up

Excessive air leakage around prongs and masks When the baby is apneic and the Edi signal is un-
challenges the ventilator’s ability to synchronize the detectable, the SERVO-i will automatically provide
assist to the patient’s needs. This is also the case backup breaths until the Edi signal is re-detected
for leakage related to cuffed and un-cuffed tubes. and automatically returns to NAVA.
NAVA is leakage-independent, calculating and
correcting delivery of support instantly to overcome
the leakage loss. NAVA back-up

4
Edi
signal

1 3
NAVA
NAVA back-up

2
Apnea
| Critical Care | SERVO-i for neonates | 13 |

NAVA opportunities. Patient-ventilator synchrony is SERVO-i WITH NAVA OFFERS


mandatory for small babies. This can be reliably achieved
with NAVA. NAVA will also normalize blood gases and • Synchrony independent of leaks
improve oxygenation4. By means of the back-up system
integrated with NAVA, the risk of hypoxia is lowered, • Edi — a vital sign for patient assessment
potentially reducing the need for controlled mechanical
ventilation. • Neural control with automatic apnea backup
| 14 | SERVO-i for neonates | Critical Care |

SERVO-i FOR NEONATES


ADAPTABLE TO YOUR CHANGING NEEDS

For more than 30 years, MAQUET has been a leader The SERVO-i is a modular, ergonomic ventilator that can
in setting mechanical ventilation standards with systems grow as your needs change. Designed for serviceability
such as SERVO-i. Today, NAVA builds on that tradition by and upgradeability, SERVO-i will continue to let you take
making true patient-ventilator synchrony possible, even advantage of all standard ventilation modes, while facilitating
for neonates. changes to your configuration as your needs change or as
innovations become available.

Essential for the non-invasive application in neonatal is the patient interface SERVO-i delivers all standard ventilation modes in one compact, easy to
systems that must be designed for minimal dead space, weight and noise use system with intuitive controls and intelligently-designed monitoring. It
levels. The possibility to change between prongs and mask is of importance also features Y Sensor measuring, continuous nebulization and is available
to avoid injuries. in MR, Transport and Heliox configurations.

NAVA Automode

PS Y Sensor

Nasal
MR
CPAP

SIMV HBO

VC Heliox

PC Transport

PRVC CO2

Bi-Vent Nebulization
| Critical Care | SERVO-i for neonates | 15 |

SERVO-i FOR NEONATES


AN ESTABLISHED TREATMENT WORLDWIDE

NAVA is used in intensive care units in countries all REFERENCES


around the world for neonatal, pediatric and adult patients. Selected publications on the topic of NAVA in neonatal care:
Clinical evidence for NAVA has been documented in multiple
1. A ldrich T, Sinderby C, McKenzie D, Estenne M, Gandevia S. Electrophysio-
clinical studies in scientific peer-reviewed journals, a body
logic techniques for the assessment of respiratory muscle function. In: the
of work that continues to grow exponentially every year. ATS/ERS Statement on Respiratory Muscle Testing. Am J Respir Crit Care
Med 2002; 166:548-558 
2. Leitner JC, Manning HL. The Hering-Breuer reflex, feedback control, and
Most aspects of both SERVO-i and NAVA are well- mechanical ventilation: the promise of neurally adjusted ventilatory assist.
documented in a number of pocket guides, case studies, Crit Care Med 2010;38:1915-1916
3. Breatnach C, Conlon NP, Stack M, Healy M, O´Hare BP. A prospective
e-learning, training and support materials. For more
crossover comparison of neurally adjusted ventilatory assist and pressu-
information, ask your MAQUET representative or visit resupport ventilation in a pediatric and neonatal intensive care population.
www.maquet.com. Pediatr Crit Care Med 2009; Jul 9. PMID 19593246
4. Stein H. NAVA in neonatal intensive care unit. European Academy of Paed-
iatrics. Copenhagen 2010;October 23
Peer-to-peer forum for sharing NAVA experience 5. Allo J, Beck J, Brander L, Brunet F, Slutsky A, Sinderby C. Influence of
neurally adjusted ventilatory assist and positive end-expiratory pressu-
The magazine Critical Care News and its associated web-
re on breathing pattern in rabbits with acute lung injury. Crit Care Med
site, www.criticalcarenews.com is a forum hosted by 2006;December;34(12):2997-3004
MAQUET Critical Care for intensive care clinicians to share 6. Rozé H, A Lafrikh. Daily titration of neurally adjusted ventilatory assist
using the diaphragm electrical activity. Intensive Care Med 2011;March 22
clinical experience of NAVA. The website is a primary source 7. Sinderby C, Beck J, Lindström L, Grassino A. Enhancement of signal
of user information about invasive and non-invasive NAVA, quality in esophageal recordings of diaphragm EMG. J. Appl. Physiol.
1997;82:1370-1377
and contains up-to-date lists of clinical literature reference
8. Campoccia Jalde F, Almadhoob AT, Beck J, Slutsky AS, Dunn MS, Sinder-
lists, patient case reports about the use of NAVA in neo- by C. Neurally adjusted ventilatory assist and pressure support ventilation
natal, pediatric and adult patients, as well as numerous in small species and the impact of instrumental dead space. Neonatology
2009;97(3):279-295
NAVA lectures and interviews with intensive care physicians 9. Ramanathan R, Sardesai S. Lung protective ventilatory strategies in very
about NAVA. low birth weight infants. J Perinatol. 2008:Suppl 1:s41-6

For more comprehensive lists of scientific studies on the topics of NAVA, please
refer to www.criticalcarenews.com and select topic under Reference List.

No. 18

News | 23
Critical Care

m.
on the diaphrag
and put pressure is not
works well but
Theme: BiVent mode
as SIMV Pressure
as user friendly logists
we have 8 neonato
Deepening knowledge Control. Since
the most common
22 | Critical Care
News
and experience of new in our NICU, ).
n is SIMV(PC
mode of ventilatio
ventilation therapies
traditionally
Stein: We have
PAGE 2 Dr Howard n with
limited ventilatio
used pressure al patient
is an occasion
SIMV. There n.
Neonatal and Pediatric Ventilation: limited ventilatio
that needs volume but this was not
Emerging Trends and Challenges PRVC
We have tried airleaks
to the large
A Symposium Summary Report successful due
using uncuffed
from Akron Children’s Hospital associated with a year ago we
heal tubes. About
endotrac been put
PAGE 16 but this has
introduced Bivent learned to use NAVA.
have
on hold as we
Clinical experience of NAVA
process
in 40 neonatal patients the weaning
Can you describe y, for example
Neonatologist Howard Stein MD, Diane you utilize currentl you determine
Howard, RRT, Educational Coordinator and how
with SIMV ion?
and Judith Gresky, RN, NICU Director, time for extubat
appropriate
Toledo Children’s Hospital
: Our usual approach to
PAGE 22 Diane Howard ers is
Judith Gresky,
RN, MSN, CMP ventilator paramet per blood
at Toledo to weaning s
and NICU Director the pressure
RRT, NPS, Education initially decrease because
Diane Howard, Respiratory Therapy Children’s Hospital. x-ray results
Coordinator
for Research and establishing gas and chest tor to chronic
Hospital is a contribu
at Toledo Children’s standards of care and training for barotrauma to minimal
and the (CLD). We wean
neonatal intensive us. Our facilities
care in China lung disease atelectasis
who work with have develope
d
s without creating
the size of Dr Bo Sun, MD,services we provide
PhD, Head of Laboratoryut the years. In pressure
the rate. If the baby
Can you describe ent, average d througho and then decrease in work of
of Pediatric Respiratory
and expandeand Intensive ed an increase
your NICU departm and staff?Care Medicine at Shanghai facility, which we complet does not have have apneic
patients our latest Children’s our space does not
number of quadrupled breathing and removed.
Hospital of Fudan ago, we
University,
1 year China
Most of our heal tube is
have 60 beds,
and
babies and families. spells, the endotrac of endotracheal
We for rooms and a trial
Judith Gresky: as 50PAGE
extra 32 have private Occasionally, ful, the
on staff as well babies now twin rooms. and if success
100 nurses have 700 – 800 also have some CPAP is ordered do not sedate
s. We we d. We
staff member 60 per baby is extubate NICU.
per year or about First impressions of the use of cantly in our
admissions of our babies signifi
an average census aa new ventilation
labor Heliox ventilator solution
patient
NAVA neonatal month, with or modes of
Stein, MD with week. We have Which types the NICU?
gist Howard about 46 per transport ally used in ion
Cindy Zimmel,
RN and neonatolo room here, and aIntensive care physician
are
Dr Ian White
tradition y is your extubat
and delivery
transport of
35-ICU of St. Peter’s Hospital, Surrey,
tothe What generall re-
nting What is the
team that provides in a 27 county United Kingdom : Prior to impleme 2007, success rate?

ce of NAVA
patients Diane Howard the fall of within 48 hours?
39% of our of Ohio ventilators in intubation rate

Clinical experien nts


st corner PAGE our SERVO-i babies with
area in the northwe of Michigan . 36 ventilating our tion rate
st corner we had been r was : Our re-intuba
and southea While this ventilato several Diane Howard on is
the VIP Bird. introduced hours after extubati anytime
Theour
of stay for need for highstate of the art when
ventilatory within 24-48 s

patie
modes of with neonate

in 40 neonatal
length nal newer low, but
The average Gestatio
performance in anesthesia lacked the PAGE 4 generally
22-23 days. years ago, it Regulated an infection
or become
patients is about weeks as Pressure they acquire themselves
about 22-23– perspectives from two n, such
ventilatio BiVent. We they can find
ages range from and we (PRVC) and more apneic,

Institutional experience of NAVA


a week
by The Volume Control
to full term,clinicians in anesthesiology ventilator within
is accredited at the earliest, to of these different back on the considered
s in 2007 and the logists on staff have used several on our babies but are not really
4,400 patient unit (NICU) in have 8 neonato Professor Capdevila, The University
modes of ventilatio
n or two. They but have become
cared for over intensive care provide around
the clock care. ent Mandato
ry
extubation failures, ventilatory support.
in Toledo, Ohio in neuro and cardiovascular intensive care patients
Hospital (CHU) of Montpellier, France
n’s Hospital III newborn s, with over Synchro nized Intermitt Control
largest Level
need
infant and parent and Professor
has Lönnqvist, pediatric with Pressure again and
Toledo Childre ion hosts the needs of the
NICU unit
Stein: This anesthesiologist Ventilation (SIMV) We have
sick
babies, the rate
is low,
ission. The institut modate the Dr Howard and Dr at Astrid Lindgren frequently used. In our older range, 50-70%
n for 32 years, has been most
Joint Comm ual units to accom been in operatio Children´s
startedHospital at Karolinska but have found
it difficult
Jim Kutsogiannis,
while inMD,
23-26 week
Darryl Ewanchuk, RRT, Craig Guenther, MD, Kevin Coghlan, RRT
once, fairly
60 beds in individ Krishnan, our
senior partner,
University
logistsHospital,
used PRVC
Stockholm, Swedenaround the endotrac
heal
and Julie moreofthan
Mitchell,d RRT, the University of Alberta Hospital in Edmonton, Canada
region, with earlier this have 8 neonato
and
due to air leaks mostly
are intubate
gestational age.
per year. – NAVA the unit. We Control is utilized typical for this
700 admissions
24
Ventilatory Assist newborns in-hospital coverage
PAGE 40 tubes. Volume testinal
ly Adjusted al patients and
we provide 4 neonatal gical gastroin
distended
ented Neural There are also on our post-sur
unit implem NAVA in neonat MSN, CMP,
hours a day. s from
babies, as their
bellies become
intensive care experience with Gresky, RN,
ners and resident
The newborn been gaining spoke with Judith
nurse practitio
family practice
programs
members have Care News d Stein, MD pediatrics and
year, and staff ologist Howar
conditions. Critical nator and neonat basis. 09-02-26 13.57.00
of different ional Coordi it on a regular
with a variety d, RRT, Educat logy and using CCnews18_090220.indd 1 09-02-26 13.56.35
r, Diane Howar and Edi techno
NICU Directo enting NAVA
experie nce in implem
regarding their CCnews18_
090220.indd
23

09-02-26 13.56.59

22
090220.indd
CCnews18_
© Maquet Critical Care AB 2013. All rights reserved. • MAQUET reserves the right to modify the design and specifications contained herein without prior notice.
Order No. MX-0897, MCV00029268 REVA • Printed in Sweden • Rev.02 English.
The following are registered or pending
trademarks of Maquet Critical Care AB:
SERVO-i and NAVA

The product NIV NAVA may be pending


regulatory approvals to be marketed in
your country. Contact your local MAQUET
representative for more information.

Maquet Critical Care AB


171 54 Solna, Sweden
Phone: +46 8 730 73 00 GETINGE GROUP is a leading global provider of products and
www.maquet.com systems that contribute to quality enhancement and cost efficien-
cy within healthcare and life sciences. We operate under the three
brands of ArjoHuntleigh, GETINGE and MAQUET. ArjoHuntleigh
focuses on patient mobility and wound management solutions.
Please visit our websites GETINGE provides solutions for infection control within health-
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